LOCUS BC143325 1610 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 7,
mRNA (cDNA clone MGC:176847 IMAGE:9051830), complete cds.
ACCESSION BC143325
VERSION BC143325.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1610)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1610)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (12-JUN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 15 Row: M Column: 21.
FEATURES Location/Qualifiers
source 1..1610
/db_xref="H-InvDB:HIT000501783"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176847 IMAGE:9051830"
/tissue_type="Liver, PCR rescued clones"
/clone_lib="NIH_MGC_291"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: TACACAAC"
gene 1..1610
/gene="CYP2A7"
/gene_synonym="CPA7"
/gene_synonym="CPAD"
/gene_synonym="CYP2A"
/gene_synonym="CYPIIA7"
/gene_synonym="P450-IIA4"
/db_xref="GeneID:1549"
/db_xref="HGNC:HGNC:2611"
/db_xref="MIM:608054"
CDS 46..1530
/gene="CYP2A7"
/gene_synonym="CPA7"
/gene_synonym="CPAD"
/gene_synonym="CYP2A"
/gene_synonym="CYPIIA7"
/gene_synonym="P450-IIA4"
/codon_start=1
/product="CYP2A7 protein"
/protein_id="AAI43326.1"
/db_xref="GeneID:1549"
/db_xref="HGNC:HGNC:2611"
/db_xref="MIM:608054"
/translation="MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIG
NYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRG
EQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAI
RSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSVMLGIFQFTSTSTGQ
LYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQ
EEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRV
IGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVF
PMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELF
LFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR"
BASE COUNT 348 a 466 c 463 g 333 t
ORIGIN
1 aggcaaacca ccccacccat caccatctgt catctcacta ccaccatgct ggcctcaggg
61 ctgcttctgg tggccttgct ggcctgcctg actgtgatgg tcttgatgtc tgtctggcag
121 cagaggaaga gcagggggaa gctgcctccg ggacccaccc cactgccctt cattggaaac
181 tacctccagc tgaacacaga gcacatatgt gactccatca tgaagttcag tgagtgctat
241 ggccccgtgt tcaccattca cttggggccc cggcgggtcg tggtgctgtg tggacatgat
301 gccgtcaggg aggctctggt ggaccaggct gaggagttca gcgggcgagg cgagcaagcc
361 accttcgact gggtcttcaa aggctatggc gtggcgttca gcaacgggga gcgcgccaag
421 cagctcctgc gctttgccat cgccaccctg agggacttcg gggtgggcaa gcgaggcatc
481 gaggagcgca tccaggagga gtcgggcttc ctcatcgagg ccatccggag cacgcacggc
541 gccaatatcg atcccacctt cttcctgagc cgcacagtct ccaatgtcat cagctccatt
601 gtctttgggg accgctttga ctatgaggac aaagagttcc tgtcactgct gagcgtgatg
661 ctaggaatct tccagttcac gtcaacctcc acggggcagc tctatgagat gttctcttcg
721 gtgatgaaac acctgccagg accacagcaa caggccttta agttgctgca agggctggag
781 gacttcatag ccaagaaggt ggagcacaac cagcgcacgc tggatcccaa ttccccacgg
841 gacttcatcg actcctttct catccgcatg caggaggagg agaagaaccc caacacggag
901 ttctacttga agaacctgat gatgagcacg ttgaacctct tcattgcagg caccgagacg
961 gtcagcacca ccctgcgcta tggcttcttg ctgctcatga agcacccaga ggtggaggcc
1021 aaggtccatg aggagattga cagagtgatc ggcaagaacc ggcagcccaa gtttgaggac
1081 cgggccaaga tgccctacat ggaggcagtg atccacgaga tccaaagatt tggagacgtg
1141 atccccatga gtttggcccg cagggttaaa aaggacacca agtttcggga ttttttcctc
1201 cctaagggca ccgaagtgtt ccctatgctg ggctccgtgc tgagagaccc cagcttcttc
1261 tccaaccctc aggacttcaa tccccagcat ttcctggatg acaaggggca gtttaagaag
1321 agtgatgctt ttgtgccctt ttccatcgga aagcggtact gtttcggaga aggcctggcc
1381 agaatggagc tctttctctt cttcaccacc gtcatgcaga acttccgcct caagtcctcc
1441 cagtcaccta aggacattga cgtgtccccc aaacacgtgg gctttgccac gatcccacga
1501 aactacacca tgagcttcct gccccgctga gcgagggctg tgccggtgca ggtctggtgg
1561 gcggggccag ggaaaggcgg ggtcagggcg gggttcgcgg aagaggcggg
//