LOCUS BC140856 3146 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH
domain 1, mRNA (cDNA clone MGC:176533 IMAGE:9021724), complete cds.
ACCESSION BC140856
VERSION BC140856.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3146)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3146)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAY-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 673 Row: o Column: 2.
FEATURES Location/Qualifiers
source 1..3146
/db_xref="H-InvDB:HIT000501601"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176533 IMAGE:9021724"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_361"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: GGGTATTA"
gene 1..3146
/gene="AGAP1"
/gene_synonym="GGAP1"
/db_xref="GeneID:116987"
/db_xref="HGNC:HGNC:16922"
/db_xref="MIM:608651"
CDS 216..2789
/gene="AGAP1"
/gene_synonym="GGAP1"
/codon_start=1
/product="AGAP1 protein"
/protein_id="AAI40857.1"
/db_xref="GeneID:116987"
/db_xref="HGNC:HGNC:16922"
/db_xref="MIM:608651"
/translation="MNYQQQLANSAAIRAEIQRFESVHPNIYSIYELLERVEEPVLQN
QIREHVIAIEDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESP
EGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYS
RMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNV
ERVFQDVAQKIVATRKKQQLSIGPCKSLPNSPSHSSVCSAQVSAVHISQTSNGGGSLS
DYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLE
SRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVH
GKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGNVTSASGS
QMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSAISSDTGLGDSVCSSPSI
SSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTW
HFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHC
VDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGN
ELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRAT
ADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTAR
DAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTI
I"
BASE COUNT 714 a 988 c 913 g 531 t
ORIGIN
1 aagtcacccg agcaagcctc cttcggggcc ggccgcaccc gccgcggcgc gctccatggg
61 ggcgcgctcc ccccgggcgg cccgctgacc cgggacgccg gggcccgctc gctcgccggc
121 cgcgcgtccc ggccatgaac tgagcccgcg ggccagcccc gcgcctgctc cgcccgcgcc
181 tttcttctcg cgcctccggg cgcggcgcct gcaccatgaa ctaccagcag cagctggcca
241 actcggctgc catccgggcc gagatccagc gcttcgagtc ggtccacccc aacatctact
301 ccatctacga gctgctggag cgcgtggagg agccggtgct gcagaaccag atccgggagc
361 acgtcatcgc catcgaagat gccttcgtga acagccagga atggacgctg agtcgatctg
421 tcccggagct caaagtggga attgtgggta acttggccag cggcaagtct gccctggtgc
481 accggtacct gacgggcaca tatgtccagg aggagtctcc ggaaggtggc aggttcaaga
541 aagagattgt cgttgatgga cagagctatc tgctgctgat cagagatgaa gggggccccc
601 cggaggcgca gtttgccatg tgggtggacg ctgttatatt tgtcttcagc ttggaggatg
661 aaataagttt ccagaccgtt taccactact acagtcgaat ggccaactat cggaacacga
721 gcgagattcc tctggttctg gtgggaaccc aggatgccat aagttctgct aacccgaggg
781 tcatcgatga cgccagggcg aggaagctct ccaacgacct gaaacggtgc acgtactacg
841 agacgtgtgc tacatacggg ctgaatgtgg agagggtctt ccaggacgtt gcccagaaga
901 ttgttgccac aaggaagaag cagcagctgt ccataggacc ctgcaagtcg ctacctaatt
961 ctcccagcca ttcctccgtc tgttccgcgc aggtgtctgc cgtgcacatc agccagacaa
1021 gtaatggagg tgggagttta agcgactatt cctcctccgt tccatcgact cccagcacca
1081 gccagaagga acttcggatc gatgttcctc ccactgccaa cacgcccacg cccgttcgca
1141 agcagtctaa gcgccggtcc aacctgttca cctctcggaa agggagcgac ccagacaaag
1201 agaagaaagg cctggagagt cgtgcggaca gcattgggag cggccgagcc atcccaatta
1261 aacagggcat gctgttgaag cgaagtggca aatcgttgaa taaagagtgg aaaaagaaat
1321 atgtcaccct gtgtgacaat ggcgtgctga cctatcatcc cagtttacat gattacatgc
1381 agaatgttca tggtaaggag attgaccttc tgagaaccac tgtgaaagtc ccagggaaga
1441 ggccaccccg agccacgtca gcctgcgcac ccatctccag ccctaaaacc aatggcctat
1501 ccaaggacat gagcagttta cacatctcac ccaattcagg gaatgtcact agtgcatctg
1561 ggtctcagat ggcaagcggc atcagcctgg tctccttcaa cagccgaccc gacggcatgc
1621 accagcgctc ctactcagtc tccagtgccg accagtggag tgaggctacg gtcattgcaa
1681 actcggccat cagcagtgac acagggctgg gtgactccgt atgctccagc cccagtatct
1741 ccagcaccac cagccccaag ctcgacccgc ccccctcccc tcacgccaac agaaagaagc
1801 accgaaggaa gaaaagcact agcaacttca aagccgacgg cctgtccggc actgctgaag
1861 aacaagaaga aaattttgag tttatcattg tgtccctcac tggccaaaca tggcactttg
1921 aagccacgac gtatgaggag cgggacgcct gggtccaagc catcgagagc cagatcctgg
1981 ccagcctgca gtcgtgcgag agcagcaaga acaagtcccg gctgacgagc cagagcgagg
2041 ccatggccct gcagtcgatc cggaacatgc gcgggaactc ccactgtgtg gactgcgaga
2101 cccagaatcc caactgggcc agtttgaact tgggagccct catgtgcatc gaatgctcag
2161 ggatccaccg gaatcttggc acccaccttt cccgagtccg atctctggac ctggatgact
2221 ggccagtcga gctcatcaag gtgatgtcat ccatcgggaa cgagctagcc aacagcgtct
2281 gggaagagag cagccagggg cggacgaaac catcggtaga ctccacaagg gaagagaagg
2341 aacggtggat ccgtgccaag tacgagcaga agctcttcct ggccccgctg ccctgcacgg
2401 agctgtccct gggccagcac ctgctgcggg ccaccgccga cgaggacctg cggacggcca
2461 tcctgctgct ggcacacggc tcccgggacg aggtgaacga gacctgcggg gagggagacg
2521 gccgcacggc gctgcatctg gcctgccgca aggggaatgt ggtcctggcg cagctcctga
2581 tctggtacgg agtggacgtc acggcccgag atgcccacgg gaacacagct ctggcctacg
2641 cccggcaggc ctccagccag gagtgcatcg acgtgctgct gcagtacggc tgccccgacg
2701 agcgcttcgt gctcatggcc acccctaacc tgtccaggag aaacaataac cggaacaaca
2761 gcagtgggag ggtgcccacc atcatctgag gaacagccgt gcccgcctgc tcgccgcacc
2821 tgggacgcgg cagcctcgcc gcattctcgc tcagaagtcg cagcacgtga gtcccgtcgc
2881 atcccctccc tcttcctggt ggccacctcc ctcccgccca cccactctca ccccaaacaa
2941 aatcacaaaa cctggacatc cctcaagggg cgaagaggcg gccgggagac tgcagaagtg
3001 gctccttttc ataaactccc ctaaaccaca cacaggagag agcgacgggc ctcggccctt
3061 tgatgatagc acatggcgca ggacccttgt cctggtggca caagggatgg ggacgcgagg
3121 gggaggggag gcgaggaaca aggaga
//