LOCUS BC140802 7186 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens desmoplakin, mRNA (cDNA clone MGC:176479
IMAGE:9021670), complete cds.
ACCESSION BC140802
VERSION BC140802.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 7186)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 7186)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAY-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 673 Row: l Column: 20.
FEATURES Location/Qualifiers
source 1..7186
/db_xref="H-InvDB:HIT000501553"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:176479 IMAGE:9021670"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_363"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: GGTGAGAG"
gene 1..7186
/gene="DSP"
/gene_synonym="DPI"
/gene_synonym="DPII"
/db_xref="GeneID:1832"
/db_xref="HGNC:HGNC:3052"
/db_xref="MIM:125647"
CDS 275..7093
/gene="DSP"
/gene_synonym="DPI"
/gene_synonym="DPII"
/codon_start=1
/product="desmoplakin"
/protein_id="AAI40803.1"
/db_xref="GeneID:1832"
/db_xref="HGNC:HGNC:3052"
/db_xref="MIM:125647"
/translation="MSCNGGSHPRINTLGRMIRAESGPDLRYEVTSGGGGTSRMYYSR
RGVITDQNSDGYCQTGTMSRHQNQNTIQELLQNCSDCLMRAELIVQPELKYGDGIQLT
RSRELDECFAQANDQMEILDSLIREMRQMGQPCDAYQKRLLQLQEQMRALYKAISVPR
VRRASSKGGGGYTCQSGSGWDEFTKHVTSECLGWMRQQRAEMDMVAWGVDLASVEQHI
NSHRGIHNSIGDYRWQLDKIKADLREKSAIYQLEEEYENLLKASFERMDHLRQLQNII
QATSREIMWINDCEEEELLYDWSDKNTNIAQKQEAFSIRMSQLEVKEKELNKLKQESD
QLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAYFQFFEEAQSTEAYL
KGLQDSIRKKYPCDKNMPLQHLLEQIKELEKEREKILEYKRQVQNLVNKSKKIVQLKP
RNPDYRSNKPIILRALCDYKQDQKIVHKGDECILKDNNERSKWYVTGPGGVDMLVPSV
GLIIPPPNPLAVDLSCKIEQYYEAILALWNQLYINMKSLVSWHYCMIDIEKIRAMTIA
KLKTMRQEDYMKTIADLELHYQEFIRNSQGSEMFGDDDKRKIQSQFTDAQKHYQTLVI
QLPGYPQHQTVTTTEITHHGTCQDVNHNKVIETNRENDKQETWMLMELQKIRRQIEHC
EGRMTLKNLPLADQGSSHHITVKINELKSVQNDSQAIAEVLNQLKDMLANFRGSEKYC
YLQNEVFGLFQKLENINGVTDGYLNSLCTVRALLQAILQTEDMLKVYEARLTEEETVC
LDLDKVEAYRCGLKKIKNDLNLKKSLLATMKTELQKAQQIHSQTSQQYPLYDLDLGKF
GEKVTQLTDRWQRIDKQIDFRLWDLEKQIKQLRNYRDNYQAFCKWLYDAKRRQDSLES
MKFGDSNTVMRFLNEQKNLHSEISGKRDKSEEVQKIAELCANSIKDYELQLASYTSGL
ETLLNIPIKRTMIQSPSGVILQEAADVHARYIELLTRSGDYYRFLSEMLKSLEDLKLK
NTKIEVLEEELRLARDANSENCNKNKFLDQNLQKYQAECSQFKAKLASLEELKRQAEL
DGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQLQKAR
QCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKASNRIQESKN
QCTQVVQERESLLVKIKVLEQDKARLQRLEDELNRAKSTLEAETRVKQRLECEKQQIQ
NDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERLQAEIKRIEERCRRKLED
STRETQSQLETERSRYQREIDKLRQRPYGSHRETQTECEWTVDTSKLVFDGLRKKVTA
MQLYECQLIDKTTLDKLLKGKKSVEEVASEIQPFLRGAGSIAGASASPKEKYSLVEAK
RKKLISPESTVMLLEAQAATGGIIDPHRNEKLTVDSAIARDLIDFDDRQQIYAAEKAI
TGFDDPFSGKTVSVSEAIKKNLIDRETGMRLLEAQIASGGVVDPVNSVFLPKDVALAR
GLIDRDLYRSLNDPRDSQKNFVDPVTKKKVSYVQLKERCRIEPHTGLLLLSVQKRSMS
FQGIRQPVTVTELVDSGILRPSTVNELESGQISYDEVGERIKDFLQGSSCIAGIYNET
TKQKLGIYEAMKIGLVRPGTALELLEAQAATGFIVDPVSNLRLPVEEAYKRGLVGIEF
KEKLLSAERAVTGYNDPETGNIISLFQAMNKELIEKGHGIRLLEAQIATGGIIDPKES
HRLPVDIAYKRGYFNEELSEILSDPSDDTKGFFDPNTEENLTYLQLKERCIKDEETGL
CLLPLKEKKKQVQTSQKNTLRKRRVVIVDPETNKEMSVQEAYKKGLIDYETFKELCEQ
ECEWEEITITGSDGSTRVVLVDRKTGSQYDIQDAIDKGLVDRKFFDQYRSGSLSLTQF
ADMISLKNGVGTSSSMGSGVSDDVFSSSRHESVSKISTISSVRNLTIRSSSFSDTLEE
SSPIAAIFDTENLEKISITEGIERGIVDSITGQRLLEAQACTGGIIHPTTGQKLSLQD
AVSQGVIDQDMATRLKPAQKAFIGFEGVKGKKKMSAAEAVKEKWLPYEAGQRFLEFQY
LTGGLVDPEVHGRISTEEAIRKGFIDGRAAQRLQDTSSYAKILTCPKTKLKISYKDAI
NRSMVEDITGLRLLEAASVSSKGLPSPYNMSSAPGSRSGSRSGSRSGSRSGSRSGSRR
GSFDATGNSSYSYSYSFSSSSIGH"
BASE COUNT 2152 a 1667 c 1870 g 1497 t
ORIGIN
1 caacaccaac acccagctcc gacgcagctc ctctgcgccc ttgccgccct ccgagccaca
61 gctttcctcc cgctcctgcc cccggcccgt cgccgtctcc gcgctcgcag cggcctcggg
121 agggcccagg tagcgagcag cgacctcgcg agccttccgc actcccgccc ggttccccgg
181 ccgtccgcct atccttggcc ccctccgctt tctccgcgcc ggcccgcctc gcttatgcct
241 cggcgctgag ccgctctccc gattgcccgc cgacatgagc tgcaacggag gctcccaccc
301 gcggatcaac actctgggcc gcatgatccg cgccgagtct ggcccggacc tgcgctacga
361 ggtgaccagc ggcggcgggg gcaccagcag gatgtactat tctcggcgcg gcgtgatcac
421 cgaccagaac tcggacggct actgtcaaac cggcacgatg tccaggcacc agaaccagaa
481 caccatccag gagctgctgc agaactgctc cgactgcttg atgcgagcag agctcatcgt
541 gcagcctgaa ttgaagtatg gagatggaat acaactgact cggagtcgag aattggatga
601 gtgttttgcc caggccaatg accaaatgga aatcctcgac agcttgatca gagagatgcg
661 gcagatgggc cagccctgtg atgcttacca gaaaaggctt cttcagctcc aagagcaaat
721 gcgagccctt tataaagcca tcagtgtccc tcgagtccgc agggccagct ccaagggtgg
781 tggaggctac acttgtcaga gtggctctgg ctgggatgag ttcaccaaac atgtcaccag
841 tgaatgtttg gggtggatga ggcagcaaag ggcggagatg gacatggtgg cctggggtgt
901 ggacctggcc tcagtggagc agcacattaa cagccaccgg ggcatccaca actccatcgg
961 cgactatcgc tggcagctgg acaaaatcaa agccgacctg cgcgagaaat ctgcgatcta
1021 ccagttggag gaggagtatg aaaacctgct gaaagcgtcc tttgagagga tggatcacct
1081 gcgacagctg cagaacatca ttcaggccac gtccagggag atcatgtgga tcaatgactg
1141 cgaggaggag gagctgctgt acgactggag cgacaagaac accaacatcg ctcagaaaca
1201 ggaggccttc tccatacgca tgagtcaact ggaagttaaa gaaaaagagc tcaataagct
1261 gaaacaagaa agtgaccaac ttgtcctcaa tcagcatcca gcttcagaca aaattgaggc
1321 ctatatggac actctgcaga cgcagtggag ttggattctt cagatcacca agtgcattga
1381 tgttcatctg aaagaaaatg ctgcctactt tcagtttttt gaagaggcgc agtctactga
1441 agcatacctg aaggggctcc aggactccat caggaagaag tacccctgcg acaagaacat
1501 gcccctgcag cacctgctgg aacagatcaa ggagctggag aaagaacgag agaaaatcct
1561 tgaatacaag cgtcaggtgc agaacttggt aaacaagtct aagaagattg tacagctgaa
1621 gcctcgtaac ccagactaca gaagcaataa acccattatt ctcagagctc tctgtgacta
1681 caaacaagat cagaaaatcg tgcataaggg ggatgagtgt atcctgaagg acaacaacga
1741 gcgcagcaag tggtacgtga cgggcccggg aggcgttgac atgcttgttc cctctgtggg
1801 gctgatcatc cctcctccga acccactggc cgtggacctc tcttgcaaga ttgagcagta
1861 ctacgaagcc atcttggctc tgtggaacca gctctacatc aacatgaaga gcctggtgtc
1921 ctggcactac tgcatgattg acatagagaa gatcagggcc atgacaatcg ccaagctgaa
1981 aacaatgcgg caggaagatt acatgaagac gatagccgac cttgagttac attaccaaga
2041 gttcatcaga aatagccaag gctcagagat gtttggagat gatgacaagc ggaaaataca
2101 gtctcagttc accgatgccc agaagcatta ccagaccctg gtcattcagc tccctggcta
2161 tccccagcac cagacagtga ccacaactga aatcactcat catggaacct gccaagatgt
2221 caaccataat aaagtaattg aaaccaacag agaaaatgac aagcaagaaa catggatgct
2281 gatggagctg cagaagattc gcaggcagat agagcactgc gagggcagga tgactctcaa
2341 aaacctccct ctagcagacc aggggtcttc tcaccacatc acagtgaaaa ttaacgagct
2401 taagagtgtg cagaatgatt cacaagcaat tgctgaggtt ctcaaccagc ttaaagatat
2461 gcttgccaac ttcagaggtt ctgaaaagta ctgctattta cagaatgaag tatttggact
2521 atttcagaaa ctggaaaata tcaatggtgt tacagatggc tacttaaata gcttatgcac
2581 agtaagggca ctgctccagg ctattctcca aacagaagac atgttaaagg tttatgaagc
2641 caggctcact gaggaggaaa ctgtctgcct ggacctggat aaagtggaag cttaccgctg
2701 tggactgaag aaaataaaaa atgacttgaa cttgaagaag tcgttgttgg ccactatgaa
2761 gacagaacta cagaaagccc agcagatcca ctctcagact tcacagcagt atccacttta
2821 tgatctggac ttgggcaagt tcggtgaaaa agtcacacag ctgacagacc gctggcaaag
2881 gatagataaa cagatcgact ttagattatg ggacctggag aaacaaatca agcaattgag
2941 gaattatcgt gataactatc aggctttctg caagtggctc tatgatgcta aacgccgcca
3001 ggattcctta gaatccatga aatttggaga ttccaacaca gtcatgcggt ttttgaatga
3061 gcagaagaac ttgcacagtg aaatatctgg caaacgagac aaatcagagg aagtacaaaa
3121 aattgctgaa ctttgtgcca attcaattaa ggattatgag ctccagctgg cctcatacac
3181 ctcaggactg gaaactctgc tgaacatacc tatcaagagg accatgattc agtccccttc
3241 tggggtgatt ctgcaagagg ctgcagatgt tcatgctcgg tacattgaac tacttacaag
3301 atctggagac tattacaggt tcttaagtga gatgctgaag agtttggaag atctgaagct
3361 gaaaaatacc aagatcgaag ttttggaaga ggagctcaga ctggcccgag atgccaactc
3421 ggaaaactgt aataagaaca aattcctgga tcagaacctg cagaaatacc aggcagagtg
3481 ttcccagttc aaagcgaagc ttgcgagcct ggaggagctg aagagacagg ctgagctgga
3541 tgggaagtcg gctaagcaaa atctagacaa gtgctacggc caaataaaag aactcaatga
3601 gaagatcacc cgactgactt atgagattga agatgaaaag agaagaagaa aatctgtgga
3661 agacagattt gaccaacaga agaatgacta tgaccaactg cagaaagcaa ggcaatgtga
3721 aaaggagaac cttggttggc agaaattaga gtctgagaaa gccatcaagg agaaggagta
3781 cgagattgaa aggttgaggg ttctactgca ggaagaaggc acccggaaga gagaatatga
3841 aaatgagctg gcaaaggcat ctaataggat tcaggaatca aagaatcagt gtactcaggt
3901 ggtacaggaa agagagagcc ttctggtgaa aatcaaagtc ctggagcaag acaaggcaag
3961 gctgcagagg ctggaggatg agctgaatcg tgcaaaatca actctagagg cagaaaccag
4021 ggtgaaacag cgcctggagt gtgagaaaca gcaaattcag aatgacctga atcagtggaa
4081 gactcaatat tcccgcaagg aggaggctat taggaagata gaatcggaaa gagaaaagag
4141 tgagagagag aagaacagtc ttaggagtga gatcgaaaga ctccaagcag agatcaagag
4201 aattgaagag aggtgcaggc gtaagctgga ggattctacc agggagacac agtcacagtt
4261 agaaacagaa cgctcccgat atcagaggga gattgataaa ctcagacagc gcccatatgg
4321 gtcccatcga gagacccaga ctgagtgtga gtggaccgtt gacacctcca agctggtgtt
4381 tgatgggctg aggaagaagg tgacagcaat gcagctctat gagtgtcagc tgatcgacaa
4441 aacaaccttg gacaaactat tgaaggggaa gaagtcagtg gaagaagttg cttctgaaat
4501 ccagccattc cttcggggtg caggatctat cgctggagca tctgcttctc ctaaggaaaa
4561 atactctttg gtagaggcca agagaaagaa attaatcagc ccagaatcca cagtcatgct
4621 tctggaggcc caggcagcta caggtggtat aattgatccc catcggaatg agaagctgac
4681 tgtcgacagt gccatagctc gggacctcat tgacttcgat gaccgtcagc agatatatgc
4741 agcagaaaaa gctatcactg gttttgatga tccattttca ggcaagacag tatctgtttc
4801 agaagccatc aagaaaaatt tgattgatag agaaaccgga atgcgcctgc tggaagccca
4861 gattgcttca gggggtgtag tagaccctgt gaacagtgtc tttttgccaa aagatgtcgc
4921 cttggcccgg gggctgattg atagagattt gtatcgatcc ctgaatgatc cccgagatag
4981 tcagaaaaac tttgtggatc cagtcaccaa aaagaaggtc agttacgtgc agctgaagga
5041 acggtgcaga atcgaaccac atactggtct gctcttgctt tcagtacaga agagaagcat
5101 gtccttccaa ggaatcagac aacctgtgac cgtcactgag ctagtagatt ctggtatatt
5161 gagaccgtcc actgtcaatg aactggaatc tggtcagatt tcttatgacg aggttggtga
5221 gagaattaag gacttcctcc agggttcaag ctgcatagca ggcatataca atgagaccac
5281 aaaacagaag cttggcattt atgaggccat gaaaattggc ttagtccgac ctggtactgc
5341 tctggagttg ctggaagccc aagcagctac tggctttata gtggatcctg ttagcaactt
5401 gaggttacca gtggaggaag cctacaagag aggtctggtg ggcattgagt tcaaagagaa
5461 gctcctgtct gcagaacgag ctgtcactgg gtataatgat cctgaaacag gaaacatcat
5521 ctctttgttc caagccatga ataaggaact catcgaaaag ggccacggta ttcgcttatt
5581 agaagcacag atcgcaaccg gggggatcat tgacccaaag gagagccatc gtttaccagt
5641 tgacatagca tataagaggg gctatttcaa tgaggaactc agtgagattc tctcagatcc
5701 aagtgatgat accaaaggat tttttgaccc caacactgaa gaaaatctta cctatctgca
5761 actaaaagaa agatgcatta aggatgagga aacagggctc tgtcttctgc ctctgaaaga
5821 aaagaagaaa caggtgcaga catcacaaaa gaataccctc aggaagcgta gagtggtcat
5881 agttgaccca gaaaccaata aagaaatgtc tgttcaggag gcctacaaga agggcctaat
5941 tgattatgaa accttcaaag aactgtgtga gcaggaatgt gaatgggaag aaataaccat
6001 cacgggatca gatggctcca ccagggtggt cctggtagat agaaagacag gcagtcagta
6061 tgatattcaa gatgctattg acaagggcct tgttgacagg aagttctttg atcagtaccg
6121 atccggcagc ctcagcctca ctcaatttgc tgacatgatc tccttgaaaa atggtgtcgg
6181 caccagcagc agcatgggca gtggtgtcag cgatgatgtt tttagcagct cccgacatga
6241 atcagtaagt aagatttcca ccatatccag cgtcaggaat ttaaccataa ggagcagctc
6301 tttttcagac accctggaag aatcgagccc cattgcagcc atctttgaca cagaaaacct
6361 ggagaaaatc tccattacag aaggtataga gcggggcatc gttgacagca tcacgggtca
6421 gaggcttctg gaggctcagg cctgcacagg tggcatcatc cacccaacca cgggccagaa
6481 gctgtcactt caggacgcag tctcccaggg tgtgattgac caagacatgg ccaccaggct
6541 gaagcctgct cagaaagcct tcataggctt cgagggtgtg aagggaaaga agaagatgtc
6601 agcagcagag gcagtgaaag aaaaatggct cccgtatgag gctggccagc gcttcctgga
6661 gttccagtac ctcacgggag gtcttgttga cccggaagtg catgggagga taagcaccga
6721 agaagccatc cggaaggggt tcatagatgg ccgcgccgca cagaggctgc aagacaccag
6781 cagctatgcc aaaatcctga cctgccccaa aaccaaatta aaaatatcct ataaggatgc
6841 cataaatcgc tccatggtag aagatatcac tgggctgcgc cttctggaag ccgcctccgt
6901 gtcgtccaag ggcttaccca gcccttacaa catgtcttcg gctccggggt cccgctccgg
6961 ctcccgctcg ggatctcgct ccggatctcg ctccgggtcc cgcagtgggt cccggagagg
7021 aagctttgac gccacaggga attcttccta ctcttattcc tactcattta gcagtagttc
7081 tattgggcac tagtagtcag ttgggagtgg ttgctatacc ttgacttcat ttatatgaat
7141 ttccacttta ttaaataata gaaaagaaaa tcccggtgct tgcagt
//