LOCUS BC139742 1639 bp mRNA linear HUM 05-APR-2007
DEFINITION Homo sapiens Rho guanine nucleotide exchange factor (GEF) 4, mRNA
(cDNA clone IMAGE:40035399), complete cds.
ACCESSION BC139742
VERSION BC139742.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1639)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1639)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-APR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCG Plate: 16 Row: d Column: 12
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1639
/db_xref="H-InvDB:HIT000391173"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40035399"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: TGTTTCAA sequenced from
the forward primer"
gene 1..1639
/gene="ARHGEF4"
/gene_synonym="ASEF"
/gene_synonym="GEF4"
/gene_synonym="STM6"
/db_xref="GeneID:50649"
/db_xref="HGNC:HGNC:684"
/db_xref="MIM:605216"
CDS 542..1120
/gene="ARHGEF4"
/gene_synonym="ASEF"
/gene_synonym="GEF4"
/gene_synonym="STM6"
/codon_start=1
/product="ARHGEF4 protein"
/protein_id="AAI39743.1"
/db_xref="GeneID:50649"
/db_xref="HGNC:HGNC:684"
/db_xref="MIM:605216"
/translation="MPWEEPAGEKPSCSHSQKAFHMEPAQKPCFTTDMVTWALLCISA
ETVRGEAPSQPRGIPHRSPVSVDDLWLEKTQRKKLQKQAHVERRLHIGAVHKDGVKCW
RKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTAVGRPCYLTRQKHPALPS
NRPQQQVLVLAEPRRKPSTFWHSISRLAPFRK"
BASE COUNT 334 a 544 c 462 g 299 t
ORIGIN
1 gccacttgcc tccacacctt tgtcctccag tttagtttct ccagaacaca ggaggaaaag
61 tgaaccgacc atcaagtgca cagccaccca ggaaggcggt aggtacctac cttcaggtat
121 ctttccggaa aagtcctggc tggcgtcccc cggcagccct cgggcccagc aggctggaat
181 cgcacacacc ctgccttcca gctctgcctg ctgcctggca tatgaaaacc ccgggacgcc
241 ctgcagaccc acgagcccca agcccctgag tcccaggcct agtgctcagc ggatgggtct
301 ccactacccc gggaggggta gcgccatctc catggtttct cttggaagct acagctacgt
361 ggacagcagt tcaggggacc ctgaaagacc caagattccc aagggccaga ccagtttcct
421 gctttctctg cagacgctaa accaagatga gcagaaggaa gagagcaggg aaggaggcca
481 gggtccgcgc ggcttgggca cagtgccctg gctcagggac cttcctggga gtgagaacca
541 catgccctgg gaagaaccag caggtgagaa gcccagttgc tctcacagtc agaaggcgtt
601 ccacatggag cctgcccaga agccctgctt caccactgac atggtgacat gggccctcct
661 ctgcatctct gcagagactg tgcgtgggga ggctccttca cagcctaggg gcatccctca
721 ccgctcgccc gtcagtgtgg atgacctgtg gctggagaag acacagagaa agaagttgca
781 gaagcaggcc cacgtcgaaa ggaggctgca cataggggca gtgcacaaag atggagtcaa
841 gtgctggaga aagacgatca ttacctctcc agagtctttg aatctcccta gaagaagcca
901 tccactctcc cagagtgctc caacgggact gaaccacatg ggctggccag agcacacacc
961 aggcactgct gttggccggc cctgctacct gacgcgccag aagcacccag ccctgcccag
1021 caaccggccc cagcagcagg tcctggtgct ggcggagccc aggcgcaagc catctacctt
1081 ctggcacagc atcagccggc tggcaccctt ccgcaagtga actggtccct gcctgacagc
1141 acctgctggg ccttcctgcc agtggccccc agtttttctt ccccgaggcc cactcggcct
1201 ggccttcctc tgcctgcaag tgagcaggga tgggctgggg agttgcttgt gccaccaaga
1261 cgtgccaggt ctgtactcct gttgtctttt tccctgctcc tggtgccctg aagagaccag
1321 caagggggca gaccccgcac tcgccacacc gccgctgcag cttgggcccc atccgccctc
1381 tggacctgtg tagggcctca ctgctggagc ggggaaaccg cagctcagcc caggcccagc
1441 tggggagaag gcgctacctg cgtgggaccc tcttctctgg aaacctaatc ctcctttcat
1501 ttcctctggg caggactctc tggccttctg tggcctgcaa tgccaggcca tgtgcccctc
1561 tgccctctag ttctccaagt ccccagcccg gccagtggtg ccaggcagct tgccacttgg
1621 gagggcagaa gccaggaat
//