LOCUS BC137283 6947 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens spectrin, beta, non-erythrocytic 1, mRNA (cDNA clone
MGC:168903 IMAGE:9021280), complete cds.
ACCESSION BC137283
VERSION BC137283.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6947)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6947)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 672 Row: l Column: 14.
FEATURES Location/Qualifiers
source 1..6947
/db_xref="H-InvDB:HIT000501227"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168903 IMAGE:9021280"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_364"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: TTCCTCTC"
gene 1..6947
/gene="SPTBN1"
/gene_synonym="betaSpII"
/gene_synonym="ELF"
/gene_synonym="SPTB2"
/db_xref="GeneID:6711"
/db_xref="HGNC:HGNC:11275"
/db_xref="MIM:182790"
CDS 296..6763
/gene="SPTBN1"
/gene_synonym="betaSpII"
/gene_synonym="ELF"
/gene_synonym="SPTB2"
/codon_start=1
/product="spectrin, beta, non-erythrocytic 1"
/protein_id="AAI37284.1"
/db_xref="GeneID:6711"
/db_xref="HGNC:HGNC:11275"
/db_xref="MIM:182790"
/translation="MELQRTSSISGPLSPAYTGQVPYNYNQLEGRFKQLQDEREAVQK
KTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLEN
VDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKK
SAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAH
YNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKR
IGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTY
RTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHE
RELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKK
HEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARR
QRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGI
QAERVRGVNASAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEES
RRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFE
QAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADA
DDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQASALP
QEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKE
QWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIK
AQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLG
NDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDV
WEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLL
TQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWE
NRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTT
MDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNR
DLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKI
EKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCAD
LDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQE
GKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPL
ATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQ
RLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEEKAKD
EQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYA
GLKDLAEERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQER
FREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTR
TQILAASYELHKFYHDAKEIFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQA
LGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDK
FRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCI
ELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVA
EAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEV
RRQQEEEERKRRPPSPEPSTKVSEEAESQQQWDTSKGEQVSQNGLPAEQGSPRVSYRS
QTYQNYKNFNSRRTASDQPWSGL"
BASE COUNT 1938 a 1720 c 1996 g 1293 t
ORIGIN
1 cgcctcctct ctgcttctcc ctcctcctca gtaatttatt tcgagcttcc aggcaagggc
61 cacggaagaa gggaaagcaa gaaattagat gcctgtgtgg taactcctcg cggagctaag
121 gtggactctc ttgcagccaa cttcccatca gatcaccctg ctggacttgc agaccggaat
181 ggggctcgcc taaggagccg agcgctgcgg aggctgctgc gtgttggatg ggagtgggag
241 ggggctggag cgagatttcc agggcgcagt cctccggggc gttacgccgg gcataatgga
301 attgcagagg acgtctagta tctccgggcc gctgtcgccg gcgtacacgg ggcaggtgcc
361 ttacaactac aaccagctgg aaggcagatt caagcagctg caagatgagc gtgaagccgt
421 gcagaagaag accttcacca agtgggtcaa ttcccacctt gcccgtgtgt cctgccggat
481 cacagacctg tacactgacc ttcgagatgg acggatgctc atcaagctgc tggaggtcct
541 ctctggagag aggctgccta aacccaccaa gggacgaatg cgcatccact gcttagagaa
601 tgtggacaag gcccttcagt tcctgaagga gcagagagtc catcttgaga acatggggtc
661 ccatgacatc gtggatggaa accaccggct gacccttggc ctcatctgga ccatcatcct
721 gcgcttccag atccaggata tcagtgtgga aactgaagac aacaaagaga agaaatctgc
781 caaggatgca ttgctgttgt ggtgccagat gaagacagct gggtacccca atgtcaacat
841 tcacaatttc accactagct ggagggacgg catggccttc aatgcactga tacacaaaca
901 ccggcctgac ctgatagatt ttgacaaact aaagaaatct aacgcacact acaacctgca
961 gaatgcattt aatctggcag aacagcacct cggcctcact aaactgttgg accccgaaga
1021 catcagcgtg gaccatcctg atgagaagtc cataatcact tatgtggtga cttattacca
1081 ctacttctct aagatgaagg ccttagctgt tgaaggaaaa cgaattggaa aggtgcttga
1141 caatgctatt gaaacagaaa aaatgattga aaagtatgaa tcacttgcct ctgaccttct
1201 ggaatggatt gaacaaacca tcatcattct gaacaatcgc aaatttgcca attcactggt
1261 cggggttcaa cagcagcttc aggcattcaa cacttaccgc actgtggaga aaccacccaa
1321 atttactgag aaggggaact tggaagtgct gctcttcacc attcagagca agatgagggc
1381 caacaaccag aaggtctaca tgccccggga ggggaagctc atctctgaca tcaacaaggc
1441 ctgggaaaga ctggaaaaag cggaacacga aagagaactg gctttgcgga atgagctcat
1501 aagacaggag aaactggaac agctcgcccg cagatttgat cgcaaggcag ctatgaggga
1561 gacttggctg agcgaaaacc agcgtctggt gtctcaggac aactttgggt ttgaccttcc
1621 tgcagttgag gccgccacaa aaaagcacga ggccattgag acagacattg ccgcatacga
1681 ggagcgtgtg caggctgtgg tagccgtggc cagggagctc gaggccgaga attaccacga
1741 catcaagcgc atcacagcga ggaaggacaa tgtcatccgg ctctgggaat acctactgga
1801 actgctcagg gcccggagac agcggctcga gatgaacctg gggctgcaga agatattcca
1861 ggaaatgctc tacattatgg actggatgga tgaaatgaag gtgctagtat tgtctcaaga
1921 ctatggcaaa cacttacttg gtgtggaaga cctgttacag aagcacaccc tggttgaagc
1981 agacattggc atccaggcag agcgggtgag aggtgtcaat gcctccgccc agaagttcgc
2041 aacagacggg gaaggttaca agccctgtga cccccaggtg atccgagacc gcgtggccca
2101 catggagttc tgttatcaag agctttgcca gctggcggct gagcgcaggg cccgtctgga
2161 agagtcccgc cgcctctgga agttcttctg ggagatggca gaagaggaag gctggatacg
2221 ggagaaggag aagatcctgt cctcggacga ttacgggaaa gacctgacca gcgtcatgcg
2281 cctgctcagc aagcaccggg cgttcgagga cgagatgagc ggccgcagtg gccactttga
2341 gcaggccatc aaggaaggcg aagacatgat cgcggaggag cacttcgggt cggagaagat
2401 ccgtgagagg atcatttaca tccgggagca gtgggccaac ctagagcagc tctcggccat
2461 tcggaagaag cgcctggagg aggcctccct gctgcaccag ttccaggcag atgctgatga
2521 cattgatgcc tggatgctgg acatcctcaa gattgtctcc agcagcgacg tgggccacga
2581 tgagtattcc acacagtctc tggtcaagaa acacaaggac gtggcggaag agatcgccaa
2641 ttacaggccc acccttgaca cgctgcacga acaagccagc gccctccccc aggagcatgc
2701 cgagtctcca gacgtgaggg gcaggctgtc gggcatcgag gagcggtata aggaggtggc
2761 agagctgacg cggctgcgga agcaggcact ccaggacact ctggccctgt acaagatgtt
2821 cagcgaggct gatgcctgtg agctctggat cgacgagaag gagcagtggc tcaacaacat
2881 gcagatccca gagaagctgg aggatctgga ggtcatccag cacagatttg agagcctaga
2941 accagaaatg aacaaccagg cttcccgggt tgcagtggtg aaccagattg cacgccagct
3001 gatgcacagc ggccacccaa gtgagaagga aatcaaagcc cagcaggaca aactcaacac
3061 aaggtggagc cagttcagag aactggttga caggaagaag gatgccctcc tgtctgccct
3121 gagcatccag aactaccacc tcgagtgcaa tgaaaccaaa tcctggattc gggaaaagac
3181 caaggtcatc gagtccaccc aggacctggg caatgacctg gctggcgtca tggccctgca
3241 gcgcaagctg accggcatgg agcgggactt ggtggccatt gaggcaaagc tgagtgacct
3301 gcagaaggag gcggagaagc tggagtccga gcaccccgac caggcccagg ccatcctgtc
3361 tcggctggcc gagatcagcg acgtgtggga ggagatgaag accaccctga aaaaccgaga
3421 ggcctccctg ggagaggcca gcaagctgca gcagttccta cgggacttgg acgacttcca
3481 gtcctggctc tctaggaccc agacagcgat cgcctcggag gacatgccaa acaccctgac
3541 cgaggctgag aagctgctca cgcagcacga gaacatcaag aacgagatcg acaactacga
3601 ggaggactac cagaagatga gggacatggg cgagatggtc acccaggggc agaccgatgc
3661 ccagtacatg tttctgcggc agcggctgca ggccctggac actggatgga acgagctcca
3721 caagatgtgg gagaatagac aaaatctcct atcccagtca catgcctacc agcagttcct
3781 cagagacacg aagcaagccg aagcctttct taacaaccag gagtatgttc tggctcacac
3841 tgaaatgcct accaccttgg aaggagctga agcagcaatt aaaaagcaag aggacttcat
3901 gaccaccatg gacgccaatg aggagaagat caatgctgtg gtggagactg gccggaggct
3961 ggtgagcgat gggaacatca actcagatcg catccaggag aaggtggact ctattgatga
4021 cagacatagg aagaatcgtg agacagccag tgaacttttg atgaggttga aggacaacag
4081 ggatctacag aaattcctgc aagattgtca agagctgtct ctctggatca atgagaagat
4141 gctcacagcc caggacatgt cttacgatga agccagaaat ctgcacagta aatggttgaa
4201 gcatcaagca tttatggcag aacttgcatc caacaaagaa tggcttgaca aaatcgagaa
4261 ggaaggaatg cagctcattt cagaaaagcc tgagacggaa gctgtggtga aggagaaact
4321 cactggttta cataaaatgt gggaagtcct tgaatccact acccagacaa aggcccagcg
4381 gctctttgat gcaaacaagg ccgaactttt cacccagagc tgtgcagatc tagacaaatg
4441 gctgcacggc ctggagagtc agattcagtc tgatgactat ggcaaagacc tgaccagtgt
4501 caatatcctg ctgaaaaagc aacagatgct ggagaatcag atggaagtgc ggaagaagga
4561 gatcgaagag ctccaaagcc aagcccaggc cctgagtcag gaagggaaga gcaccgacga
4621 ggtagacagc aagcgcctca ccgtgcagac caagttcatg gagttgctgg agcccttgaa
4681 cgagaggaag cataacctgc tggcctccaa agagatccat cagttcaaca gggatgtgga
4741 ggacgagatc ttgtgggttg gagagaggat gcctttggca acttccacgg atcatggcca
4801 caacctccag actgtgcagc tgttaataaa gaaaaatcag accctccaga aagaaatcca
4861 ggggcaccag cctcgcattg acgacatctt tgagaggagc caaaacatcg tcactgacag
4921 cagcagcctc agcgctgagg ccatcagaca gaggcttgcc gacctgaagc agctgtgggg
4981 tctcctcatt gaggagacag agaaacgcca caggcggctg gaggaggcgc acagggccca
5041 gcagtactac tttgacgctg ctgaggccga agcctggatg agcgagcagg agctgtacat
5101 gatgtcagag gagaaggcca aggatgagca gagtgctgtc tccatgttga agaagcacca
5161 gatcttagaa caagctgtgg aggactatgc agagaccgtg catcagctct ccaagaccag
5221 ccgggccctg gtggccgaca gccatcctga aagtgagcgc attagcatgc ggcagtccaa
5281 agtggataaa ctgtacgctg gtctgaaaga ccttgctgaa gagagaagag gcaagctgga
5341 tgagagacac aggttattcc agctcaaccg ggaggtggac gacctggagc agtggatcgc
5401 tgagagggag gtggtcgcag ggtcccatga actgggacag gactatgagc atgtcacgat
5461 gttacaagaa cgattccggg agtttgcccg agacaccggg aacattgggc aggagcgcgt
5521 ggacacggtc aatcacctgg cagatgagct catcaactct ggacattcag atgccgccac
5581 catcgctgaa tggaaggatg gcctcaatga agcctgggcc gacctcctgg agctcattga
5641 cacaagaaca cagattcttg ccgcttccta tgaactgcac aagttttacc acgatgccaa
5701 ggagatcttt gggcgtatac aggacaaaca caagaaactc cctgaggagc ttgggagaga
5761 tcagaacaca gtggagacct tacagagaat gcacactaca tttgagcatg acatccaggc
5821 tctgggcaca caggtgaggc agctgcagga ggatgcagcc cgcctccagg cggcctatgc
5881 gggtgacaag gccgacgata tccagaagcg cgagaacgag gtcctggaag cctggaagtc
5941 cctcctggac gcctgtgaga gccgcagggt gcggctggtg gacacagggg acaagttccg
6001 cttcttcagc atggtgcgcg acctcatgct ctggatggag gatgtcatcc ggcagatcga
6061 ggcccaggag aagccaaggg atgtatcatc tgttgaactc ttaatgaata atcatcaagg
6121 catcaaagct gaaattgatg cacgtaatga cagtttcaca acctgcattg aacttgggaa
6181 atccctgttg gcgagaaaac actatgcatc tgaggagatc aaggaaaaat tactgcagtt
6241 gacggaaaag aggaaagaaa tgatcgacaa gtgggaagac cgatgggaat ggttaagact
6301 gattctggag gtccatcagt tctcaagaga cgccagtgtg gccgaggcct ggctgcttgg
6361 acaggagccg tacctatcca gccgagagat aggccagagc gtggacgagg tggagaagct
6421 catcaagcgc cacgaggcat ttgaaaagtc tgcagcaacc tgggatgaga ggttctctgc
6481 cctggaaagg ctgactacat tggagttact ggaagtgcgc agacagcaag aggaagagga
6541 gaggaagagg cggccgcctt ctcccgagcc gagcacgaag gtttcagagg aagccgagtc
6601 ccagcagcag tgggatactt caaaaggaga acaagtttcc caaaacggtt tgccagctga
6661 acagggatct ccacgggtta gttaccgctc tcaaacctac caaaactaca aaaactttaa
6721 tagcagacgg acagccagtg accagccatg gtctggactg tgaagttcac taccatttgt
6781 caagaatcac cctttccaaa tcctctgggt tttgactttt tggcttccac ttcacccaaa
6841 atgttaaaat ttttacttaa ttcatagcct tccttggttt catatttgtt tgcatttaat
6901 tcatgtttga gtctcttaac tgatggatgc ccacttgcct taaagca
//