LOCUS BC137270 1634 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens autoimmune regulator, mRNA (cDNA clone MGC:168890
IMAGE:9021267), complete cds.
ACCESSION BC137270
VERSION BC137270.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1634)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1634)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 672 Row: l Column: 1.
FEATURES Location/Qualifiers
source 1..1634
/db_xref="H-InvDB:HIT000501214"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168890 IMAGE:9021267"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: ATCATTAC"
gene 1..1634
/gene="AIRE"
/gene_synonym="AIRE1"
/gene_synonym="APS1"
/gene_synonym="APSI"
/gene_synonym="PGA1"
/db_xref="GeneID:326"
/db_xref="HGNC:HGNC:360"
/db_xref="MIM:607358"
CDS 417..1463
/gene="AIRE"
/gene_synonym="AIRE1"
/gene_synonym="APS1"
/gene_synonym="APSI"
/gene_synonym="PGA1"
/codon_start=1
/product="AIRE protein"
/protein_id="AAI37271.1"
/db_xref="GeneID:326"
/db_xref="HGNC:HGNC:360"
/db_xref="MIM:607358"
/translation="MWLVYSSGAPGTQQPARNRVFFPIGMAPGGVCWRPDGWGTGGQG
RISGPGSMGAGQRLGSSGTQRCCWGSCFGKEVALRRVLHPSPVCMGVSCLCQKNEDEC
AVCRDGGELICCDGCPRAFHLACLSPPLREIPSGTWRCSSCLQATVQEVQPRAEEPRP
QEPPVETPLPPGLRSAGEEVRGPPGEPLAGMDTTLVYKHLPAPPSAAPLPGLDSSALH
PLLCVGPEGQQNLAPGARCGVCGDGTDVLRCTHCAAAFHWRCHFPAGTSRPGTGLRCR
SCSGDVTPAPVEGVLAPSPARLAPGPAKDDTASHEPALHRDDLESLLSEHTFDGILQW
AIQSMARPAAPFPS"
BASE COUNT 268 a 498 c 572 g 296 t
ORIGIN
1 tgggaatgcc atgctcatct ttcgtcccca gcatggtttc ttaatggggt agaagcagtg
61 tggggggtgc ctgccgtggt gggttacaga tcttgaccac ttggcaccag gggctctgtg
121 gggccctggc acttagcagt gacaggagcc agtcctgccc tgcaggagca cccgggctgg
181 tgggcgtctg ggggattgtt agaatgagtg aggtcattgc cgtgcaggac cagcctagcc
241 tggctgtctg gggggattct ggaggaagtg gtacctggga gacccctgaa ggcacagcag
301 gcaccatcca ggcagggcac aaggacggtg ggggctgcag gtggaggatt cagcaggcgc
361 tgaggtcggg agagacctcc ctgggcctgg ccccactgcc ctgtgaggaa gggttcatgt
421 ggttggtgta cagttccggg gcccctggaa cgcagcagcc tgcaagaaac cgggttttct
481 tcccaatagg gatggccccg gggggtgtct gttggagacc agatggatgg ggaacaggtg
541 gtcagggcag aatttcaggc cctggcagca tgggagcagg gcagagactg gggagttcag
601 gtacccagag atgctgctgg gggagctgtt ttgggaagga ggtggctctc aggagggtgc
661 tgcaccccag cccagtctgc atgggcgtct cttgcctgtg ccagaagaat gaggacgagt
721 gtgccgtgtg tcgggacggc ggggagctca tctgctgtga cggctgccct cgggccttcc
781 acctggcctg cctgtcccct ccgctccggg agatccccag tgggacctgg aggtgctcca
841 gctgcctgca ggcaacagtc caggaggtgc agccccgggc agaggagccc cggccccagg
901 agccacccgt ggagaccccg ctccccccgg ggcttaggtc ggcgggagag gaggtaagag
961 gtccacctgg ggaaccccta gccggcatgg acacgactct tgtctacaag cacctgccgg
1021 ccccgccttc tgcagccccg ctgccagggc tggactcctc ggccctgcac cccctactgt
1081 gtgtgggtcc tgagggtcag cagaacctgg ctcctggtgc gcgttgcggg gtgtgcggag
1141 atggtacgga cgtgctgcgg tgtactcact gcgccgctgc cttccactgg cgctgccact
1201 tcccagccgg cacctcccgg cccgggacgg gcctgcgctg cagatcctgc tcaggagacg
1261 tgaccccagc ccctgtggag ggggtgctgg cccccagccc cgcccgcctg gcccctgggc
1321 ctgccaagga tgacactgcc agtcacgagc ccgctctgca cagggatgac ctggagtccc
1381 ttctgagcga gcacaccttc gacggcatcc tgcagtgggc catccagagc atggcccgtc
1441 cggcggcccc cttcccctcc tgaccccaga tggccgggac atgcagctct gatgagagag
1501 tgctgagaag gacacctcct tcctcagtcc tggaagccgg ccggctggga tcaagaaggg
1561 gacagcgcca cctcttgtca gtgctcggct gtaaacagct ctgtgtttct ggggacacca
1621 gccatcatgt gcct
//