LOCUS BC137128 4522 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens solute carrier family 6 (neurotransmitter transporter,
taurine), member 6, mRNA (cDNA clone MGC:168748 IMAGE:9021125),
complete cds.
ACCESSION BC137128
VERSION BC137128.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4522)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4522)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 672 Row: f Column: 3.
FEATURES Location/Qualifiers
source 1..4522
/db_xref="H-InvDB:HIT000501094"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168748 IMAGE:9021125"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_313"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: GGGGGAAT"
gene 1..4522
/gene="SLC6A6"
/gene_synonym="TAUT"
/db_xref="GeneID:6533"
/db_xref="HGNC:HGNC:11052"
/db_xref="MIM:186854"
CDS 273..2135
/gene="SLC6A6"
/gene_synonym="TAUT"
/codon_start=1
/product="solute carrier family 6 (neurotransmitter
transporter, taurine), member 6"
/protein_id="AAI37129.1"
/db_xref="GeneID:6533"
/db_xref="HGNC:HGNC:11052"
/db_xref="MIM:186854"
/translation="MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKW
SSKIDFVLSVAGGFVGLGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIG
QYTSEGGITCWEKICPLFSGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWA
HCNHSWNTPHCMEDTMRKNKSVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKW
DLALCLLLVWLVCFFCIWKGVRSTGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKF
YLYPDITRLEDPQVWIDAGTQIFFSYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNS
GTSFVSGFAIFSILGFMAQEQGVDIADVAESGPGLAFIAYPKAVTMMPLPTFWSILFF
IMLLLLGLDSQFVEVEGQITSLVDLYPSFLRKGYRREIFIAFVCSISYLLGLTMVTEG
GMYVFQLFDYYAASGVCLLWVAFFECFVIAWIYGGDNLYDGIEDMIGYRPGPWMKYSW
AVITPVLCVGCFIFSLVKYVPLTYNKTYVYPNWAIGLGWSLALSSMLCVPLVIVIRLC
QTEGPFLVRVKYLLTPREPNRWAVEREGATPYNSRTVMNGALVKPTHIIVETMM"
BASE COUNT 1033 a 1148 c 1195 g 1146 t
ORIGIN
1 gacacgcgag gtcaggaaga agccgcttat aaattaccgc ttccttcgcg ccgccgccaa
61 cgccgagccc cgaggaccgc aagcccagag gacaagctgc gccaagaggg agtgcggagc
121 gttcacccag cgggtcagag agcgagcggg caggcagccc ccggccggcg gaacccggca
181 cagccgagca gagcgcgggc ggcgccgcag ccaccccaga tccagaacca gaaccacagc
241 ccttctgagg agctcccaaa caaagcaagg agatggccac caaggagaag ctgcagtgtc
301 tgaaagattt ccacaaggac atcctgaagc cctcaccagg gaagagccca ggcacgcggc
361 ctgaggacga ggctgaggga aaacctccgc agagggagaa gtggtctagc aagatcgact
421 ttgtgctctc tgtggctggc ggcttcgtgg gcttgggcaa cgtctggcgc ttcccgtacc
481 tctgctacaa gaatggtgga ggtgcgtttc tcataccgta ttttattttc ctgtttggga
541 gcggcctgcc tgtgtttttc ttggagatca tcataggcca gtacacctct gaagggggca
601 tcacctgctg ggaaaagatc tgccccttgt tctctggtat cggctatgcc tccgttgtaa
661 ttgtgtccct cctgaatgtc tactacatcg tcatcctggc ctgggccaca tactacctgt
721 tccagtcctt ccagaaggag ctgccctggg cacactgcaa ccacagctgg aacacacctc
781 actgcatgga ggacaccatg cgcaagaaca agagtgtctg gatcaccatc agctccacca
841 acttcacctc ccctgtcatc gagttctggg agcgcaacgt gctgagcttg tcccctggaa
901 tcgaccaccc aggctctctg aaatgggacc tcgctctctg ccttctttta gtctggctag
961 tgtgtttctt ctgcatctgg aagggcgtca ggtccactgg gaaggtcgtc tacttcacag
1021 ccacttttcc attcgccatg ctcctggtgc tgctggtccg agggctgacg ctgccgggcg
1081 cgggcgcagg catcaagttc tatctgtatc ctgacatcac ccgccttgag gacccacagg
1141 tgtggattga cgctgggact cagatattct tctcttatgc catctgcctg ggggctatga
1201 cctcgctggg gagctacaac aagtacaagt ataactcgta cagggactgt atgctgctgg
1261 gatgcctgaa cagtggtacc agttttgtgt ctggcttcgc aattttttcc atcctgggct
1321 tcatggcaca agagcaaggg gtggacattg ctgatgtggc tgagtcaggt cctggcctgg
1381 ccttcattgc ctacccaaaa gctgtgacaa tgatgccgct gcccacattt tggtccattc
1441 ttttttttat tatgcttctc ttgcttggac tggatagcca gtttgttgaa gttgaaggac
1501 agatcacatc cttggttgat ctttacccat ccttcctaag gaagggttat cgtcgggaaa
1561 tcttcatcgc cttcgtgtgt agcatcagct acctgctggg gctgacgatg gtgacggagg
1621 gtggcatgta tgtgtttcag ctctttgact actatgcagc tagcggtgta tgccttttgt
1681 gggttgcatt ctttgaatgt tttgttattg cctggatata tggaggtgat aacctttatg
1741 atggtattga ggacatgatt ggctatcggc ccgggccctg gatgaagtac agctgggctg
1801 tgatcactcc agttctctgt gttggatgtt tcatcttctc gctcgtcaag tacgtacccc
1861 tgacctacaa caaaacatac gtgtacccca actgggccat tgggctgggc tggagcctgg
1921 ccctttcctc catgctctgc gttcccttgg tcatcgtcat ccgcctctgc cagactgagg
1981 ggccgttcct tgtgagagtc aagtacctgc tgaccccaag ggaacccaac cgctgggctg
2041 tggagcgcga gggagccaca ccttacaact ctcgcaccgt catgaacggc gctctcgtga
2101 aaccgaccca catcattgtg gagaccatga tgtgagctct ctcgggtcga cggggccggc
2161 ggctttcctg ctgtttacta acattagatt ctcataggac caggtttaca gagctttata
2221 tttgcactag gatttttttt tttttgtaat tgtcacagaa aatgtaattg tgggtatgtg
2281 tgcgtgcgtg tgtgtgtgtg tgtgtgtatc gtgtgtgtgt gttttgtttt gatttggggg
2341 atattttgta caaaaagaaa acccacggga agatgtccgt ggagaggcag agctttcata
2401 ctgaattaga tgtattttat gggaatttgg taaatttttc tttgtatttt tttttttaca
2461 tataagtata tatacactta gagattgtca tatactttta ccacttgaat tgatcttctt
2521 gccagcaata gatctcattt tcaaaagcaa ttcttcggtg ctgtgtagct ggcagaaagt
2581 tctgtccagt aaacgcagga tggaattttc ctgggactct acacccatct taaggtggta
2641 taccttccaa atcctggttc agatggaaga aatagcagga gagaggaccc attagctggc
2701 agacccaggg ggaagaaagg agggctgtga ggagatacct cattaaactt ggcttagtga
2761 agaagagaga tgccaaagga atgaaccaac ccttcacata aaggagactg gctgaagctg
2821 aatgaggagg ccctatagca gaagtctgat tctaagagca gtagaaactt gtaccagaag
2881 caaaatccca cttttaattt tgagatggtg agtggatagt cagtagaccg tcagaaccac
2941 tggccagaga gggagctgct agagatccaa gaaggctggc aggaatgagg ctcacaactc
3001 agcctcgcaa gaggtggcag aggcacagga ggccacagtc cttcctgggg cattccaggc
3061 agagaaggag cagaggctct cccggcagga gctggggtct cagggctcag atgagtctgt
3121 tgcatttgaa tggggtcata gcaggttctg gtcattcccc aagcaacatc tcagcatctc
3181 ttaaagttgc ctgcaggaat gaagcatgac atacctgttg agggactagg ggagtggtgg
3241 ggaggtgagt ggaccaaagg atataggccc caggcatgca gatgggcccg gtgtcgggga
3301 ggggtgcttt ctttcctcat ctccccactc cccactctca gcctgggaga ctcctgccaa
3361 gccctcatta aagatgccac cctgggctgc cctggcacct agcaaggcac accaagaaca
3421 gcttttgagt ctgtatcctc cactggggga agtgctccca gttcagaaca agggcagccc
3481 gtggtgctga cctaggatat aacaaagctc ttcacttcaa aacccctgca atagctgggt
3541 ttacagacat ttaccacctg cggacccaaa agagaaggcc taggagagtt ttctagaagg
3601 ttgggattgt cagggtcctg gcccctcaga actggcttga tcaagggcct tatgtggagc
3661 agaggttgtc tctgaaccag gagagaaggt actatacctt tcaaatcccc agggcagaca
3721 cacccccacc cagcccctat ttggacctaa actgtgccat ttgaacagtc acttccaagc
3781 tcagtctaaa tgaaaccgaa acgtgaccac gcacaaaggc agtcactgcc tcgaggggtg
3841 cagaccgcag aattttcaca gcaggggctc ttggaaccct ggaaaccccc ttcttaaatt
3901 tgggaggagg agtatgcctt tggtgtcccc ctcccaaggg gcaattctga accccatctt
3961 tggcaggcat acatatttca ctgtttccaa agctatctac tctgccaaac aacacccagt
4021 cctattccaa actctcaaca attctatctt gttcctgttt ttctatgtat ttatggttgc
4081 catttgtgtc tgatttgatt ttactgtttt ttccctgatt ttatggagta gcattgtgac
4141 ctgttttcct ttgtcttata taactttagt aaactaacca ctgtcaatga ttgagggcag
4201 gtggcacgtg gggaagaggg gacttggcac gcagtggcta cctgggcatt tgtggtcatt
4261 tcagtttcca tctccccagc gggggctccc tgggtgaaag gccacagtat tttgggttgg
4321 taggcaaatt gcaacattct ggacatggcc tgaggaaggc ctcttcttat aagattctca
4381 gaccaaattc tagaccaaag acacatgcag accaagtccc caggccccgc ctggaaggaa
4441 gtcgttcctc aactctcccc aaggcacctg tctccaatca gagccctctc gcccagccag
4501 ccctggctct gtgtgcagag ca
//