LOCUS BC137117 4072 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens kelch domain containing 5, mRNA (cDNA clone MGC:168737
IMAGE:9021114), complete cds.
ACCESSION BC137117
VERSION BC137117.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4072)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4072)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 672 Row: e Column: 16.
FEATURES Location/Qualifiers
source 1..4072
/db_xref="H-InvDB:HIT000501085"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168737 IMAGE:9021114"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_313"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: AGATGGCG"
gene 1..4072
/gene="KLHDC5"
/db_xref="GeneID:57542"
/db_xref="HGNC:HGNC:29252"
CDS 44..1561
/gene="KLHDC5"
/codon_start=1
/product="kelch domain containing 5"
/protein_id="AAI37118.1"
/db_xref="GeneID:57542"
/db_xref="HGNC:HGNC:29252"
/translation="MSAEEMVQIRLEDRCYPVSKRKLIEQSDYFRALYRSGMREALSQ
EAGGPEVQQLRGLSAPGLRLVLDFINAGGAREGWLLGPRGEKGGGVDEDEEMDEVSLL
SELVEAASFLQVTSLLQLLLSQVRLNNCLEMYRLAQVYGLPDLQEACLRFMVVHFHEV
LCKPQFHLLGSPPQAPGDVSLKQRLREARMTGTPVLVALGDFLGGPLAPHPYQGEPPS
MLRYEEMTERWFPLANNLPPDLVNVRGYGSAILDNYLFIVGGYRITSQEISAAHSYNP
STNEWLQVASMNQKRSNFKLVAVNSKLYAIGGQAVSNVECYNPEQDAWNFVAPLPNPL
AEFSACECKGKIYVIGGYTTRDRNMNILQYCPSSDMWTLFETCDVHIRKQQMVSVEET
IYIVGGCLHELGPNRRSSQSEDMLTVQSYNTVTRQWLYLKENTSKSGLNLTCALHNDG
IYIMSRDVTLSTSLEHRVFLKYNIFSDSWEAFRRFPAFGHNLLVSSLYLPNKAET"
BASE COUNT 1069 a 867 c 956 g 1180 t
ORIGIN
1 cgcagatctg gcggtgagcg ctgccgcccc ggggccccca gccatgtcgg ccgaggagat
61 ggtgcagatc cgcctggagg accgctgcta cccggtgagc aagaggaagc tcatcgagca
121 gagcgactac ttccgcgccc tctaccgctc cggcatgcgc gaggccctga gccaggaggc
181 cggcggcccg gaggtgcagc agctgcgcgg cctcagcgcg ccgggcctgc ggctggtgct
241 ggacttcatc aacgccggcg gggcccgcga aggctggctc ctgggcccgc gcggggaaaa
301 gggcggcggg gtggacgagg acgaggagat ggatgaggtg agcctgctgt ccgagctggt
361 ggaggcggcc tccttcctgc aggtcacgtc cctgctgcag ctgctgctgt cccaggtgcg
421 gctcaataac tgcctggaga tgtaccgcct ggcgcaggtg tacgggctgc ccgacctgca
481 ggaggcctgc ctgcgcttca tggtcgtcca cttccacgag gtgctgtgca agccccagtt
541 ccacctcctg gggtctcctc cccaagctcc aggggatgtc agcctgaagc agaggctgag
601 ggaggcccgg atgactggga ctcctgtcct cgtggccctc ggggacttcc tggggggacc
661 cctggcccct cacccctacc agggggagcc cccgtccatg ctcaggtacg aggagatgac
721 tgagcgttgg ttcccgctgg ccaacaacct tcctcccgac ctggtcaatg tcaggggcta
781 tgggtctgcc atcctggaca actacctctt catagtgggc gggtacagga tcactagcca
841 ggagatctcc gctgcgcatt cctacaaccc cagcaccaac gagtggctcc aggtggcctc
901 catgaaccag aagaggtcta acttcaaact tgtggctgtt aattcaaaac tctatgccat
961 cggagggcag gccgtttcta acgttgagtg ttacaacccc gagcaggatg cgtggaattt
1021 tgtggcgccc ttacccaatc ctctggctga gttctctgcc tgtgagtgta agggaaaaat
1081 ttatgtcatt ggaggataca ctaccagaga ccggaacatg aacattttgc agtactgccc
1141 ctcttccgac atgtggacgc tctttgaaac atgtgacgtc cacattcgca agcagcagat
1201 ggtgtctgtg gaagagacca tctacatcgt gggggggtgt ctccacgagc tggggcccaa
1261 ccgcaggagc agccagagcg aggacatgct caccgtgcag tcctacaaca ccgtcacccg
1321 ccagtggctc tacctcaagg agaacacgtc caaatcgggt cttaacttga cttgtgcgct
1381 ccataacgac ggcatctaca tcatgagcag agacgtcacc ctgtcgacca gcttggaaca
1441 ccgagtgttc ctcaagtaca acatcttttc agatagttgg gaagcatttc ggcgttttcc
1501 agcttttgga cataacttgc tggtttcttc tctttatctg cccaataaag cagaaacatg
1561 actgaattga attggtagat gaaaaaaacc tggttcaagt tttttttaaa atgtggtgtc
1621 ccattccaag ggagaccaat tcctaaaggg taaagaaggg ttaaagtagg tcacatatat
1681 acagtagcag ctgtaaataa gcttacttga actaattact tgaaaactgg tggaaaaaag
1741 agaccaactt tgttattttt taaattattg atttttaaat tatgggagca aatccatctc
1801 caaacatgat actcttgggc caatgacgga tcatcaaaat gtagattcat tgtgtctgtg
1861 tggtaaaggg ccaaagtcaa taattgggac aaatggtaaa gatgatttta aaatctgttg
1921 tatttaggtc ccttgacata tcattagcac cttaagtgag aggttttctt tttcttatca
1981 gtgtccttga caagcattca tattaacata ttcattctct cttctccatc acccataccc
2041 acacatacat ctagtatgtt tagggttctg tgttcagata ttttgtttgc acactacttt
2101 ttaggaaact tataatgatg gagccctaca gtgaatcctt accagtgttc agtcctcccc
2161 aaaacttgca taaaaatatt cttagctatt tttccagcct tttttgcagt tacaaatgct
2221 ggataaatag actgataaaa cctcttattt tatttatgtg gcaggttgca tatttatgtg
2281 gacacatagg ttgcactgct aggcattctg tattgtttta aagaggatat attatttaga
2341 aaaatggaca tatgaatatt attaaaaatt gagtcttaaa tttaaatggg aagggaagaa
2401 aacaccaaat aagaaaaaaa tttgccttta agagttactt ttgttgaatg tatttgactt
2461 agttcttatt ttaaggctaa aaaaactttg tcatatttaa gtcggcagct ttctaattta
2521 atcttagctt tgtaattcat gttttgcttt tgtggactaa ggtaaggaca gcatttaaat
2581 atttgtgctg gagtgagggg aagaagctgt tacagaagtg gaatggtttc tggtggtatt
2641 tctgaagtta ggtaaagtgc tttacttgcc ttggttgtta attgaaatag aattcagctc
2701 aagcagttgt tttcagtgag tgagttaaca ataaaagctt ctgccaatca tagatcaaca
2761 ttcctcaaaa atacatacac tcatacttat ggaaatttta ttttgattga aaacactctg
2821 aaattatctg atattttgta atggcatcag ttaaactgtg agctggattc catctttctg
2881 cagtaacagc gggcagaacc atttcagtta gcatgtgcct cactttaaga aagtcctgta
2941 ggggaaaaaa aaaactgtca gagcgaattc atgcattcaa caaacactta tgagtgcctg
3001 gagtatgccg tccactgtgc agatgtagga caggggctaa tcacttagag ttcttcagtt
3061 tattagagga gtgactacag ggtttcttta caactatggc ctctagtata cttaaaataa
3121 gcgtccagtt ataaaaagcc tatttgcaca actttttggg aatacttcta ttaactaaaa
3181 tgaggtaagc cattattttg gacatagaaa cagatctttg tatcttgtca ccaaataatc
3241 ttacctctag tctacttaca actttgtaag ggtttctaag ctatgcccat ttattcccaa
3301 atattaagcc cttaaaaaaa taaaacctct gaaccaaaat cttcccagga atagtactta
3361 atagatttta atgttaattt atattcattg tagaattgaa tttccagtga cctgtaattt
3421 cattacatat attttaaaat ctatttattt tagatggtgt taacttttcg ttgctgaaga
3481 gcttaacttt ttaaaggctt tgtcctatac atttagaaga tgagtcagtt gaattagtac
3541 tggacaaaca gttggagatt agtttgcaaa taagcatatc atatcaaata caatattcca
3601 gccaaccagt taattctctt cctggttaca ttcattgggt ctatttgcct aatgttgaca
3661 attagattct tggaccaagt gagggtgtac tctgatccac aaagctcttt tataaaccag
3721 gtttgaggtt gtgtgtgtgt gtgtgtgtgg gtgtgtgtgt gtgtgtgtgt gtgtatgttt
3781 gcatattata gctctcttta agacagacat ctaaaaagat tttggttatt ctgggctgcc
3841 agcagtacgt gggaaaggtg gaatgtgcaa taggaacaga tctgtgcatt ttgtgacatc
3901 gtccttcctg ctgtgcacat cagctgtgat gacattttga gggtagtttt aatttagctc
3961 ggttctcttg ttggtgccag tattacattg aagactacct atgatagagg caatgttgct
4021 ttgaaaatct cccttcaggc ggaggttgca gtgagccgag attgtgccat tg
//