LOCUS BC137091 1499 bp mRNA linear HUM 30-JUN-2008
DEFINITION Homo sapiens fat mass and obesity associated, mRNA (cDNA clone
IMAGE:9021088), complete cds.
ACCESSION BC137091
VERSION BC137091.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1499)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1499)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 672 Row: d Column: 14
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1499
/db_xref="H-InvDB:HIT000501059"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:9021088"
/tissue_type="Lung, PCR rescued clones"
/clone_lib="NIH_MGC_298"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: TCACCTCT"
gene 1..1499
/gene="FTO"
/db_xref="GeneID:79068"
/db_xref="HGNC:HGNC:24678"
/db_xref="MIM:610966"
CDS 103..423
/gene="FTO"
/codon_start=1
/product="FTO protein"
/protein_id="AAI37092.1"
/db_xref="GeneID:79068"
/db_xref="HGNC:HGNC:24678"
/db_xref="MIM:610966"
/translation="MAQLEALWKKMEGVTNAVLHEVKREGLPVEQRNEILTAILASLT
ARQNLRREWHARCQSRIARTLPADQKPECRPYWEKDDASMPLPFDLTDIVSELRGQLL
EAKP"
BASE COUNT 424 a 338 c 345 g 392 t
ORIGIN
1 tccacgtttc tttagcgggc agtggtcgag tttgagtggc tgaggcagtt ttggtttcaa
61 ggcaatcgat acagaaagtg cactgactgg tggtgtcaac ccatggctca actggaagca
121 ctgtggaaga agatggaggg tgtgacaaat gctgtgcttc atgaagttaa aagagagggg
181 ctccccgtgg aacaaaggaa tgaaatcttg actgccatcc ttgcctcgct cactgcacgc
241 cagaacctga ggagagaatg gcatgccagg tgccagtcac gaattgcccg aacattacct
301 gctgatcaga agccagaatg tcggccatac tgggaaaagg atgatgcttc gatgcctctg
361 ccgtttgacc tcacagacat cgtttcagaa ctcagaggtc agcttctgga agcaaaaccc
421 tagaaggagc acaagtctca ggcggaggag aaaaagagat cggcttttct cctccaacgt
481 tgtcatgggc ttaagcaaga gcagtggaga cttctcttgg cccctagatt gtagcacccg
541 ggtcccaatc caaaacagct aggaaatggt gcccatgaag ttttaaatgt tttaaaatga
601 ccctgtgtta tagtctgatt tggtgttaaa caggaccttc ttcccccaaa attgttcaga
661 ttataaaatg tgagccattc agcccccaag gtccagggca ggcgacagga acgagcccag
721 cgtgtgacaa agcctaacct actttcctct ttcccaagct ttttcagaga ctctggagtg
781 gacccagccc tctggggaaa gacagaactt agagacatcc cagttactca ccacacccat
841 agtgctgtcc aatatggtag ccactagcta gctgtggcta cttcaattta aattcagttt
901 taattttaat taaaaatgca gctcttcagt cgccctggcc acatttcaag tgcttaacag
961 cctcatgtgg ctagtgactg ctgtattgga cggtacagat atggaacatt ttcatcatcg
1021 aagaaagtcc tattggacaa cacttctata aaaagtttga gagcaggaat tctcatttcc
1081 attcgtctgt agcttctatc cccaaaggca aagaaactaa aagagaaatg actcattgaa
1141 gattggcctc tttcctttct ctaagacaaa cctaagtaaa agcctgagct ttgagtccta
1201 tgctcagcac acgggaagga gatgttaata attaaaataa agttgatatc ctgtctttag
1261 ggagttccct tgatctcttg aaagagacac agccccattt acattatttc gtggatttca
1321 ccagcatagt atagtttttt tctgtaagtc cctcattctt atgtaataac aggtggaact
1381 gaggtttgaa gaacctcagt ggcccatcct gatgacattg gagactcaaa gagacaagag
1441 agagtagggt ttaaaacctg agctttaaga ctcccactag cttcgtgtcc tttggcatg
//