LOCUS BC136766 2506 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens methyltransferase like 4, mRNA (cDNA clone MGC:168379
IMAGE:9020756), complete cds.
ACCESSION BC136766
VERSION BC136766.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2506)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2506)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 671 Row: f Column: 18.
FEATURES Location/Qualifiers
source 1..2506
/db_xref="H-InvDB:HIT000500757"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168379 IMAGE:9020756"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_310"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: CATTCACG"
gene 1..2506
/gene="METTL4"
/gene_synonym="HsT661"
/db_xref="GeneID:64863"
/db_xref="HGNC:HGNC:24726"
CDS 540..1958
/gene="METTL4"
/gene_synonym="HsT661"
/codon_start=1
/product="methyltransferase like 4"
/protein_id="AAI36767.1"
/db_xref="GeneID:64863"
/db_xref="HGNC:HGNC:24726"
/translation="MSVVHQLSAGWLLDHLSFINKINYQLHQHHEPCCRKKEFTTSVH
FESLQMDSVSSSGVCAAFIASDSSTKPENDDGGNYEMFTRKFVFRPELFDVTKPYITP
AVHKECQQSNEKEDLMNGVKKEISISIIGKKRKRCVVFNQGELDAMEYHTKIRELILD
GSLQLIQEGLKSGFLYPLFEKQDKGSKPITLPLDACSLSELCEMAKHLPSLNEMEHQT
LQLVEEDTSVTEQDLFLRVVENNSSFTKVITLMGQKYLLPPKSSFLLSDISCMQPLLN
YRKTFDVIVIDPPWQNKSVKRSNRYSYLSPLQIKQIPIPKLAAPNCLLVTWVTNRQKH
LRFIKEELYPSWSVEVVAEWHWVKITNSGEFVFPLDSPHKKPYEGLILGRVQEKTALP
LRNADVNVLPIPDHKLIVSVPCTLHSHKPPLAEVLKDYIKPDGEYLELFARNLQPGWT
SWGNEVLKFQHVDYFIALESGS"
BASE COUNT 744 a 460 c 514 g 788 t
ORIGIN
1 tggactgaaa ggggcgtttt tcatgatcac tatttagatg ggtgctgttt tcctgaggag
61 agtctgggaa ggcggcgtcc gcttttctga caagggaaga ggctactttg tccttttaag
121 gattcaatga cttcctgact tggaggatgt ggacctagtg gctagaccca aggaccaaag
181 caagaagtcg tggggggccc aggaagacag gaggatcaca ttgggattcc agacataaga
241 tcaggtttta accccctttg gccaaatttt ggctgaaaat gttgaattat caactctgaa
301 attaaaaaga aagtttatat taaaacattg caattttcct tagaatttct gtatatatta
361 acatcatgaa tgataaattc tcttcaatgt gcatgtcagg tttttgtact tgtatatcaa
421 atctatctgt gtgtatgaag tgtatgttta ttgaaataca agatatttaa gaagctgatc
481 tggaaagttg gattttcatt ctagttccta attcccagag gcttttttaa aggaagggaa
541 tgtctgtggt acaccagttg tcagctgggt ggttactgga tcatctttct tttatcaaca
601 agataaacta tcaacttcac cagcatcatg aaccttgttg ccgtaaaaag gagttcacta
661 cttctgttca ctttgagtct cttcaaatgg attctgtgtc ctcctctgga gtctgtgctg
721 catttattgc ttctgactct tccactaagc cagagaatga tgatggagga aattatgaaa
781 tgttcacacg aaaatttgtt tttcgacctg aactgtttga tgtcaccaaa ccttatataa
841 ctccagctgt tcataaagaa tgccagcaaa gtaatgaaaa ggaagatctg atgaatggtg
901 ttaaaaaaga aatctccatt tctattattg ggaagaagcg taaaagatgt gttgttttca
961 atcaaggtga attggatgct atggaatacc atacaaagat cagggagctg attttggatg
1021 gatctttaca gttgatccag gaaggtctca aaagtggttt tctttatcca ctttttgaaa
1081 aacaggacaa gggtagtaag cccattactt taccacttga cgcctgcagt ttgtcagaat
1141 tatgtgaaat ggcaaagcat ttgccttctc tgaatgaaat ggaacatcag acattacaat
1201 tggtggaaga ggatacatct gttacagaac aggatttatt tttgcgagtt gttgaaaaca
1261 actctagctt tacaaaagtg attactttaa tgggacagaa atacctgcta ccaccgaaaa
1321 gcagttttct tttatctgac atttcttgta tgcaaccact tctaaactat aggaaaacat
1381 ttgatgtaat tgtgatagat ccaccatggc agaacaaatc agttaaaaga agtaataggt
1441 acagttattt gtcacccctg caaataaagc aaatacctat ccctaaattg gctgctccaa
1501 actgtcttct tgttacttgg gtgaccaata gacagaagca cctacgtttt ataaaggaag
1561 aactttatcc ctcttggtct gtggaggtag ttgctgagtg gcactgggta aaaataacca
1621 attcaggaga atttgtgttc ccattagatt ctccacacaa aaagccctac gaaggtctta
1681 tactggggag ggttcaagaa aaaactgctc taccattgag gaatgcagat gtaaacgtgc
1741 tccccattcc agaccacaaa ttaattgtca gcgtgccctg tactcttcac tcacataagc
1801 caccgcttgc tgaggtttta aaagactaca tcaagccaga tggggaatat ttggagttgt
1861 ttgctcgaaa tttacagcca ggttggacta gttggggcaa tgaagttctc aaatttcagc
1921 atgtggatta ttttattgct ctggagtctg gaagctgact atgatcttga ttaaagtagt
1981 ggtttcttca ttgtttcctc accacttttc ccttaattct aagtcatttt tttattttgt
2041 taccaaccca tattcttaga atataaacag gacttgtttt tttcagtaag ggaccagaag
2101 tgactagcct tcatgtaatt ttaagatgaa ttttacttga gttgcactaa cattctatgt
2161 tattctagac tatacaaatt aagtggtaag cagttataaa gacggcaaga ccatgctatt
2221 gaaaaagttc agaaaacata caccgtggac cagaggtctt aatcctatct atggatgtgt
2281 tttgtgtgac ccatacagtg ttgtaaaaaa cacttagaac cattattcta aaaaatgggg
2341 ctatttcaca ttaaagtcca gatttctgct tctttttaaa catcagaggc tctggctaca
2401 cagaggcctt tttttctttc ctggcatcag tctgcaggac caagcggtgg tggctcactt
2461 gggaagagcc ttgtgctctc cactttgcca cagtaccact gccacc
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