LOCUS BC136566 3819 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens phosphodiesterase 3B, cGMP-inhibited, mRNA (cDNA clone
MGC:168179 IMAGE:9020556), complete cds.
ACCESSION BC136566
VERSION BC136566.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3819)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3819)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 670 Row: n Column: 10.
FEATURES Location/Qualifiers
source 1..3819
/db_xref="H-InvDB:HIT000500579"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168179 IMAGE:9020556"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: AGTGCACT"
gene 1..3819
/gene="PDE3B"
/gene_synonym="cGIPDE1"
/gene_synonym="HcGIP1"
/db_xref="GeneID:5140"
/db_xref="HGNC:HGNC:8779"
/db_xref="MIM:602047"
CDS 247..3585
/gene="PDE3B"
/gene_synonym="cGIPDE1"
/gene_synonym="HcGIP1"
/codon_start=1
/product="phosphodiesterase 3B, cGMP-inhibited"
/protein_id="AAI36567.1"
/db_xref="GeneID:5140"
/db_xref="HGNC:HGNC:8779"
/db_xref="MIM:602047"
/translation="MRRDERDAKAMRSLQPPDGAGSPPESLRNGYVKSCVSPLRQDPP
RGFFFHLCRFCNVELRPPPASPQQPRRCSPFCRARLSLGALAAFVLALLLGAEPESWA
AGAAWLRTLLSVCSHSLSPLFSIACAFFFLTCFLTRTKRGPGPGRSCGSWWLLALPAC
CYLGDFLVWQWWSWPWGDGDAGSAAPHTPPEAAAGRLLLVLSCVGLLLTLAHPLRLRH
CVLVLLLASFVWWVSFTSLGSLPSALRPLLSGLVGGAGCLLALGLDHFFQIREAPLHP
RLSSAAEEKVPVIRPRRRSSCVSLGETAASYYGSCKIFRRPSLPCISREQMILWDWDL
KQWYKPHYQNSGGGNGVDLSVLNEARNMVSDLLTDPSLPPQVISSLRSISSLMGAFSG
SCRPKINPLTPFPGFYPCSEIEDPAEKGDRKLNKGLNRNSLPTPQLRRSSGTSGLLPV
EQSSRWDRNNGKRPHQEFGISSQGCYLNGPFNSNLLTIPKQRSSSVSLTHHVGLRRAG
VLSSLSPVNSSNHGPVSTGSLTNRSPIEFPDTADFLNKPSVILQRSLGNAPNTPDFYQ
QLRNSDSNLCNSCGHQMLKYVSTSESDGTDCCSGKSGEEENIFSKESFKLMETQQEEE
TEKKDSRKLFQEGDKWLTEEAQSEQQTNIEQEVSLDLILVEEYDSLIEKMSNWNFPIF
ELVEKMGEKSGRILSQVMYTLFQDTGLLEIFKIPTQQFMNYFRALENGYRDIPYHNRI
HATDVLHAVWYLTTRPVPGLQQIHNGCGTGNETDSDGRINHGRIAYISSKSCSNPDES
YGCLSSNIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAA
SAWNLYLSRPEYNFLLHLDHVEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNS
NGIEWSNENDRLLVCQVCIKLADINGPAKVRDLHLKWTEGIVNEFYEQGDEEANLGLP
ISPFMDRSSPQLAKLQESFITHIVGPLCNSYDAAGLLPGQWLEAEEDNDTESGDDEDG
EELDTEDEEMENNLNPKPPRRKSRRRIFCQLMHHLTENHKIWKEIVEEEEKCKADGNK
LQVENSSLPQADEIQVIEEADEEE"
BASE COUNT 979 a 933 c 980 g 927 t
ORIGIN
1 agaggcggca gctaaactgg tcctggagag aagccccttc cgcccctctc ctcagccagc
61 atgtcccgga ctccgccgct cctcagtccg cgcggtgggg accccgggcc gtggcggccg
121 gcgcagccct gacgggttgc gaaccagggg gcgccccgaa cgcgggggtt ggggtctggg
181 agcgcgagcg gccgctacgg tacgagcggg gtgtgctgag tcccgtggcc acccccggcc
241 ccagccatga ggagggacga gcgagacgcc aaagccatgc ggtccctgca gccgccggat
301 ggggccggct cgccccccga gagtctgagg aacggctacg tgaagagctg cgtgagcccc
361 ttgcggcagg accctccgcg cggcttcttc ttccacctct gccgcttctg caacgtggag
421 ctgcggccgc cgccggcctc tccccagcag ccgcggcgct gctccccctt ctgccgggcg
481 cgcctctcgc tgggcgccct ggctgccttt gtcctcgccc tgctgctggg cgcggaaccc
541 gagagctggg ctgccggggc cgcctggctg cggacgctgc tgagcgtgtg ttcgcacagc
601 ttgagccccc tcttcagcat cgcctgtgcc ttcttcttcc tcacctgctt cctcacccgg
661 accaagcggg gacccggccc gggccggagc tgcggctcct ggtggctgct ggcgctgccc
721 gcctgctgtt acctggggga cttcttggtg tggcagtggt ggtcttggcc ttggggggat
781 ggcgacgcag ggtccgcggc cccgcacacg cccccggagg cggcagcggg caggttgctg
841 ctggtgctga gctgcgtagg gctgctgctg acgctcgcgc acccgctgcg gctccggcac
901 tgcgttctgg tgctgctcct ggccagcttc gtctggtggg tctccttcac cagcctcggg
961 tcgctgccct ccgccctcag gccgctgctc tccggcctgg tggggggcgc tggctgcctg
1021 ctggccctgg ggttggatca cttctttcaa atcagggaag cgcctcttca tcctcgactg
1081 tccagtgccg ccgaagaaaa agtgcctgtg atccgacccc ggaggaggtc cagctgcgtg
1141 tcgttaggag aaactgcagc cagttactat ggcagttgca aaatattcag gagaccgtcg
1201 ttgccttgta tttccagaga acagatgatt ctttgggatt gggacttaaa acaatggtat
1261 aagcctcatt atcaaaattc tggaggtgga aatggagttg atctttcagt gctaaatgag
1321 gctcgcaata tggtgtcaga tcttctgact gatccaagcc ttccaccaca agtcatttcc
1381 tctctacgga gtattagtag cttaatgggt gctttctcag gttcctgtag gccaaagatt
1441 aatcctctca caccatttcc tggattttac ccctgttctg aaatagagga cccagctgag
1501 aaaggggata gaaaacttaa caagggacta aataggaata gtttgccaac tccacagctg
1561 aggagaagct caggaacttc aggattgcta cctgttgaac agtcttcaag gtgggatcgt
1621 aataatggca aaagacctca ccaagaattt ggcatttcaa gtcaaggatg ctatctaaat
1681 gggcctttta attcaaatct actgactatc ccgaagcaaa ggtcatcttc tgtatcactg
1741 actcaccatg taggtctcag aagagctggt gttttgtcca gtctgagtcc tgtgaattct
1801 tccaaccatg gaccagtgtc tactggctct ctaactaatc gatcacccat agaatttcct
1861 gatactgctg attttcttaa taagccaagc gttatcttgc agagatctct gggcaatgca
1921 cctaatactc cagattttta tcagcaactt agaaattctg atagcaatct gtgtaacagc
1981 tgtggacatc aaatgctgaa atatgtttca acatctgaat cagatggtac agattgctgc
2041 agtggaaaat caggtgaaga agaaaacatt ttctcgaaag aatcattcaa acttatggaa
2101 actcaacaag aagaggaaac agagaagaaa gacagcagaa aattatttca ggaaggtgat
2161 aagtggctaa cagaagaggc acagagtgaa cagcaaacaa atattgaaca ggaagtatca
2221 ctggacctga ttttagtaga agagtatgac tcattaatag aaaagatgag caactggaat
2281 tttccaattt ttgaacttgt agaaaagatg ggagagaaat caggaaggat tctcagtcag
2341 gttatgtata ccttatttca agacactggt ttattggaaa tatttaaaat tcccactcaa
2401 caatttatga actattttcg tgcattagaa aatggctatc gagacattcc ttatcacaat
2461 cgtatacatg ccacagatgt gctacatgca gtttggtatc tgacaacacg gccagttcct
2521 ggcttacagc agatccacaa tggttgtgga acaggaaatg aaacagattc tgatggtaga
2581 attaaccatg ggcgaattgc ttatatttct tcgaagagct gctctaatcc tgatgagagt
2641 tatggctgcc tgtcttcaaa cattcctgca ttagaattga tggctctata cgtggcagct
2701 gccatgcatg attatgatca cccagggagg acaaatgcat ttctagtggc tacaaatgcc
2761 cctcaggcag ttttatacaa tgacagatct gttctggaaa atcatcatgc tgcgtcagct
2821 tggaatctat atctttctcg cccagaatac aacttccttc ttcatcttga tcatgtggaa
2881 ttcaagcgct ttcgtttttt agtcattgaa gcaatccttg ctacggatct taaaaagcat
2941 tttgattttc tcgcagaatt caatgccaag gcaaatgatg taaatagtaa tggcatagaa
3001 tggagtaatg aaaatgatcg cctcttggta tgccaggtgt gcatcaaact ggcagatata
3061 aatggcccag caaaagttcg agacttgcat ttgaaatgga cagaaggcat tgtcaatgaa
3121 ttttatgagc agggagatga agaagcaaat cttggtctgc ccatcagtcc attcatggat
3181 cgttcttctc ctcaactagc aaaactccaa gaatctttta tcacccacat agtgggtccc
3241 ctgtgtaact cctatgatgc tgctggtttg ctaccaggtc agtggttaga agcagaagag
3301 gataatgata ctgaaagtgg tgatgatgaa gacggtgaag aattagatac agaagatgaa
3361 gaaatggaaa acaatctaaa tccaaaacca ccaagaagga aaagcagacg gcgaatattt
3421 tgtcagctaa tgcaccacct cactgaaaac cacaagatat ggaaggaaat cgtagaggaa
3481 gaagaaaaat gtaaagctga tgggaataaa ctgcaggtgg agaattcctc cttacctcaa
3541 gcagatgaga ttcaggtaat tgaagaggca gatgaagagg aatagcgaca gtttgagtaa
3601 aagaaaagtc atattgaaga agcccagagg gttgtgccca ggggcagaaa tcattgccta
3661 gtgttcaccg gctgactctc aactgaccat tcccatgtgg acaggcctta atactgtgag
3721 aggatccttg ctctgctggc agtttcccac tcctatgcac tttcacagga actagaaaac
3781 tattcttaaa ccaaaaatac catccgtgtt gacccatgt
//