LOCUS BC136516 2759 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens taste receptor, type 1, member 1, mRNA (cDNA clone
MGC:168129 IMAGE:9020506), complete cds.
ACCESSION BC136516
VERSION BC136516.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2759)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2759)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 670 Row: l Column: 8.
FEATURES Location/Qualifiers
source 1..2759
/db_xref="H-InvDB:HIT000500531"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168129 IMAGE:9020506"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: CCCTCGGT"
gene 1..2759
/gene="TAS1R1"
/gene_synonym="gm148"
/gene_synonym="T1R1"
/gene_synonym="TR1"
/db_xref="GeneID:80835"
/db_xref="HGNC:HGNC:14448"
/db_xref="MIM:606225"
CDS 96..2621
/gene="TAS1R1"
/gene_synonym="gm148"
/gene_synonym="T1R1"
/gene_synonym="TR1"
/codon_start=1
/product="taste receptor, type 1, member 1"
/protein_id="AAI36517.1"
/db_xref="GeneID:80835"
/db_xref="HGNC:HGNC:14448"
/db_xref="MIM:606225"
/translation="MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLF
PLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQL
YDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLS
PFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSD
DYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERMQCLMRHLAQAGATVVVVFSS
RQLARVFFESVVLTNLTGKVWVASEAWALSRHITGVPGIQRIGMVLGVAIQKRAVPGL
KAFEEAYARADKEAPRPCHKGSWCSSNQLCRECQAFMAHTMPKLKAFSMSSAYNAYRA
VYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRV
VTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHT
SWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFG
EPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLF
VMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSI
SAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLS
SLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST"
BASE COUNT 508 a 836 c 782 g 633 t
ORIGIN
1 aagttaggaa gcatccggca gctgccttct atttaagcaa ctggcctcct tagaggccac
61 tccttggcca tgccaggcgc gggcatctgg ccagcatgct gctctgcacg gctcgcctgg
121 tcggcctgca gcttctcatt tcctgctgct gggcctttgc ctgccatagc acggagtctt
181 ctcctgactt caccctcccc ggagattacc tcctggcagg cctgttccct ctccattctg
241 gctgtctgca ggtgaggcac agacccgagg tgaccctgtg tgacaggtct tgtagcttca
301 atgagcatgg ctaccacctc ttccaggcta tgcggcttgg ggttgaggag ataaacaact
361 ccacggccct gctgcccaac atcaccctgg ggtaccagct gtatgatgtg tgttctgact
421 ctgccaatgt gtatgccacg ctgagagtgc tctccctgcc agggcaacac cacatagagc
481 tccaaggaga ccttctccac tattccccta cggtgctggc agtgattggg cctgacagca
541 ccaaccgtgc tgccaccaca gccgccctgc tgagcccttt cctggtgccc atgattagct
601 atgcggccag cagcgagacg ctcagcgtga agcggcagta tccctctttc ctgcgcacca
661 tccccaatga caagtaccag gtggagacca tggtgctgct gctgcagaag ttcgggtgga
721 cctggatctc tctggttggc agcagtgacg actatgggca gctaggggtg caggcactgg
781 agaaccaggc cactggtcag gggatctgca ttgctttcaa ggacatcatg cccttctctg
841 cccaggtggg cgatgagagg atgcagtgcc tcatgcgcca cctggcccag gccggggcca
901 ccgtcgtggt tgttttttcc agccggcagt tggccagggt gtttttcgag tccgtggtgc
961 tgaccaacct gactggcaag gtgtgggtcg cctcagaagc ctgggccctc tccaggcaca
1021 tcactggggt gcccgggatc cagcgcattg ggatggtgct gggcgtggcc atccagaaga
1081 gggctgtccc tggcctgaag gcgtttgaag aagcctatgc ccgggcagac aaggaggccc
1141 ctaggccttg ccacaagggc tcctggtgca gcagcaatca gctctgcaga gaatgccaag
1201 ctttcatggc acacacgatg cccaagctca aagccttctc catgagttct gcctacaacg
1261 cataccgggc tgtgtatgcg gtggcccatg gcctccacca gctcctgggc tgtgcctctg
1321 gagcttgttc caggggccga gtctacccct ggcagctttt ggagcagatc cacaaggtgc
1381 atttccttct acacaaggac actgtggcgt ttaatgacaa cagagatccc ctcagtagct
1441 ataacataat tgcctgggac tggaatggac ccaagtggac cttcacggtc ctcggttcct
1501 ccacatggtc tccagttcag ctaaacataa atgagaccaa aatccagtgg cacggaaagg
1561 acaaccaggt gcctaagtct gtgtgttcca gcgactgtct tgaagggcac cagcgagtgg
1621 ttacgggttt ccatcactgc tgctttgagt gtgtgccctg tggggctggg accttcctca
1681 acaagagtga cctctacaga tgccagcctt gtgggaaaga agagtgggca cctgagggaa
1741 gccagacctg cttcccgcgc actgtggtgt ttttggcttt gcgtgagcac acctcttggg
1801 tgctgctggc agctaacacg ctgctgctgc tgctgctgct tgggactgct ggcctgtttg
1861 cctggcacct agacacccct gtggtgaggt cagcaggggg ccgcctgtgc tttcttatgc
1921 tgggctccct ggcagcaggt agtggcagcc tctatggctt ctttggggaa cccacaaggc
1981 ctgcgtgctt gctacgccag gccctctttg cccttggttt caccatcttc ctgtcctgcc
2041 tgacagttcg ctcattccaa ctaatcatca tcttcaagtt ttccaccaag gtacctacat
2101 tctaccacgc ctgggtccaa aaccacggtg ctggcctgtt tgtgatgatc agctcagcgg
2161 cccagctgct tatctgtcta acttggctgg tggtgtggac cccactgcct gctagggaat
2221 accagcgctt cccccatctg gtgatgcttg agtgcacaga gaccaactcc ctgggcttca
2281 tactggcctt cctctacaat ggcctcctct ccatcagtgc ctttgcctgc agctacctgg
2341 gtaaggactt gccagagaac tacaacgagg ccaaatgtgt caccttcagc ctgctcttca
2401 acttcgtgtc ctggatcgcc ttcttcacca cggccagcgt ctacgacggc aagtacctgc
2461 ctgcggccaa catgatggct gggctgagca gcctgagcag cggcttcggt gggtattttc
2521 tgcctaagtg ctacgtgatc ctctgccgcc cagacctcaa cagcacagag cacttccagg
2581 cctccattca ggactacacg aggcgctgcg gctccacctg accagtgggt cagcaggcac
2641 ggctggcagc cttctctgcc ctgagggtcg aaggtcgagc aggccggggg tgtccgggag
2701 gtctttgggc atcgcggtct ggggttggga cgtgtaagcg cctgggagag cctagacca
//