LOCUS BC136515 2760 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens taste receptor, type 1, member 1, mRNA (cDNA clone
MGC:168128 IMAGE:9020505), complete cds.
ACCESSION BC136515
VERSION BC136515.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2760)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2760)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 670 Row: l Column: 7.
FEATURES Location/Qualifiers
source 1..2760
/db_xref="H-InvDB:HIT000500530"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168128 IMAGE:9020505"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: AACAGGCA"
gene 1..2760
/gene="TAS1R1"
/gene_synonym="gm148"
/gene_synonym="T1R1"
/gene_synonym="TR1"
/db_xref="GeneID:80835"
/db_xref="HGNC:HGNC:14448"
/db_xref="MIM:606225"
CDS 97..2622
/gene="TAS1R1"
/gene_synonym="gm148"
/gene_synonym="T1R1"
/gene_synonym="TR1"
/codon_start=1
/product="taste receptor, type 1, member 1"
/protein_id="AAI36516.1"
/db_xref="GeneID:80835"
/db_xref="HGNC:HGNC:14448"
/db_xref="MIM:606225"
/translation="MLLCTARLVGLQLLISCCWAFACHSTESSPDFTLPGDYLLAGLF
PLHSGCLQVRHRPEVTLCDRSCSFNEHGYHLFQAMRLGVEEINNSTALLPNITLGYQL
YDVCSDSANVYATLRVLSLPGQHHIELQGDLLHYSPTVLAVIGPDSTNRAATTAALLS
PFLVPMISYAASSETLSVKRQYPSFLRTIPNDKYQVETMVLLLQKFGWTWISLVGSSD
DYGQLGVQALENQATGQGICIAFKDIMPFSAQVGDERMQCLMRHLAQAGATVVVVFSS
RQLARVFFESVVLTNLTGKVWVASEAWALSRHITGVPGIQRIGMVLGVAIQKRAVPGL
KAFEEAYARADKEAPRPCHKGSWCSSNQLCRECQAFMAHTMPKLKAFSMSSAYNAYRA
VYAVAHGLHQLLGCASGACSRGRVYPWQLLEQIHKVHFLLHKDTVAFNDNRDPLSSYN
IIAWDWNGPKWTFTVLGSSTWSPVQLNINETKIQWHGKDNQVPKSVCSSDCLEGHQRV
VTGFHHCCFECVPCGAGTFLNKSDLYRCQPCGKEEWAPEGSQTCFPRTVVFLALREHT
SWVLLAANTLLLLLLLGTAGLFAWHLDTPVVRSAGGRLCFLMLGSLAAGSGSLYGFFG
EPTRPACLLRQALFALGFTIFLSCLTVRSFQLIIIFKFSTKVPTFYHAWVQNHGAGLF
VMISSAAQLLICLTWLVVWTPLPAREYQRFPHLVMLECTETNSLGFILAFLYNGLLSI
SAFACSYLGKDLPENYNEAKCVTFSLLFNFVSWIAFFTTASVYDGKYLPAANMMAGLS
SLSSGFGGYFLPKCYVILCRPDLNSTEHFQASIQDYTRRCGST"
BASE COUNT 508 a 835 c 783 g 634 t
ORIGIN
1 gaagttagga agcatccggc agctgccttc tatttaagca actggcctcc ttagaggcca
61 ctccttggcc atgccaggcg cgggcatctg gccagcatgc tgctctgcac ggctcgtctg
121 gtcggcctgc agcttctcat ttcctgctgc tgggcctttg cctgccatag cacggagtct
181 tctcctgact tcaccctccc cggagattac ctcctggcag gcctgttccc tctccattct
241 ggctgtctgc aggtgaggca cagacccgag gtgaccctgt gtgacaggtc ttgtagcttc
301 aatgagcatg gctaccacct cttccaggct atgcggcttg gggttgagga gataaacaac
361 tccacggccc tgctgcccaa catcaccctg gggtaccagc tgtatgatgt gtgttctgac
421 tctgccaatg tgtatgccac gctgagagtg ctctccctgc cagggcaaca ccacatagag
481 ctccaaggag accttctcca ctattcccct acggtgctgg cagtgattgg gcctgacagc
541 accaaccgtg ctgccaccac agccgccctg ctgagccctt tcctggtgcc catgattagc
601 tatgcggcca gcagcgagac gctcagcgtg aagcggcagt atccctcttt cctgcgcacc
661 atccccaatg acaagtacca ggtggagacc atggtgctgc tgctgcagaa gttcgggtgg
721 acctggatct ctctggttgg cagcagtgac gactatgggc agctaggggt gcaggcactg
781 gagaaccagg ccactggtca ggggatctgc attgctttca aggacatcat gcccttctct
841 gcccaggtgg gcgatgagag gatgcagtgc ctcatgcgcc acctggccca ggccggggcc
901 accgtcgtgg ttgttttttc cagccggcag ttggccaggg tgtttttcga gtccgtggtg
961 ctgaccaacc tgactggcaa ggtgtgggtc gcctcagaag cctgggccct ctccaggcac
1021 atcactgggg tgcccgggat ccagcgcatt gggatggtgc tgggcgtggc catccagaag
1081 agggctgtcc ctggcctgaa ggcgtttgaa gaagcctatg cccgggcaga caaggaggcc
1141 cctaggcctt gccacaaggg ctcctggtgc agcagcaatc agctctgcag agaatgccaa
1201 gctttcatgg cacacacgat gcccaagctc aaagccttct ccatgagttc tgcctacaac
1261 gcataccggg ctgtgtatgc ggtggcccat ggcctccacc agctcctggg ctgtgcctct
1321 ggagcttgtt ccaggggccg agtctacccc tggcagcttt tggagcagat ccacaaggtg
1381 catttccttc tacacaagga cactgtggcg tttaatgaca acagagatcc cctcagtagc
1441 tataacataa ttgcctggga ctggaatgga cccaagtgga ccttcacggt cctcggttcc
1501 tccacatggt ctccagttca gctaaacata aatgagacca aaatccagtg gcacggaaag
1561 gacaaccagg tgcctaagtc tgtgtgttcc agcgactgtc ttgaagggca ccagcgagtg
1621 gttacgggtt tccatcactg ctgctttgag tgtgtgccct gtggggctgg gaccttcctc
1681 aacaagagtg acctctacag atgccagcct tgtgggaaag aagagtgggc acctgaggga
1741 agccagacct gcttcccgcg cactgtggtg tttttggctt tgcgtgagca cacctcttgg
1801 gtgctgctgg cagctaacac gctgctgctg ctgctgctgc ttgggactgc tggcctgttt
1861 gcctggcacc tagacacccc tgtggtgagg tcagcagggg gccgcctgtg ctttcttatg
1921 ctgggctccc tggcagcagg tagtggcagc ctctatggct tctttgggga acccacaagg
1981 cctgcgtgct tgctacgcca ggccctcttt gcccttggtt tcaccatctt cctgtcctgc
2041 ctgacagttc gctcattcca actaatcatc atcttcaagt tttccaccaa ggtacctaca
2101 ttctaccacg cctgggtcca aaaccacggt gctggcctgt ttgtgatgat cagctcagcg
2161 gcccagctgc ttatctgtct aacttggctg gtggtgtgga ccccactgcc tgctagggaa
2221 taccagcgct tcccccatct ggtgatgctt gagtgcacag agaccaactc cctgggcttc
2281 atactggcct tcctctacaa tggcctcctc tccatcagtg cctttgcctg cagctacctg
2341 ggtaaggact tgccagagaa ctacaacgag gccaaatgtg tcaccttcag cctgctcttc
2401 aacttcgtgt cctggatcgc cttcttcacc acggccagcg tctacgacgg caagtacctg
2461 cctgcggcca acatgatggc tgggctgagc agcctgagca gcggcttcgg tgggtatttt
2521 ctgcctaagt gctacgtgat cctctgccgc ccagacctca acagcacaga gcacttccag
2581 gcctccattc aggactacac gaggcgctgc ggctccacct gaccagtggg tcagcaggca
2641 cggctggcag ccttctctgc cctgagggtc gaaggtcgag caggccgggg gtgtccggga
2701 ggtctttggg catcgcggtc tggggttggg acgtgtaagc gcctgggaga gcctagacca
//