LOCUS BC136474 4029 bp mRNA linear HUM 12-MAY-2008
DEFINITION Homo sapiens kinesin family member 11, mRNA (cDNA clone MGC:168086
IMAGE:9020463), complete cds.
ACCESSION BC136474
VERSION BC136474.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4029)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4029)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 670 Row: j Column: 13.
FEATURES Location/Qualifiers
source 1..4029
/db_xref="H-InvDB:HIT000500491"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:168086 IMAGE:9020463"
/tissue_type="Lung, PCR rescued clones"
/clone_lib="NIH_MGC_300"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: TTTCTCCC"
gene 1..4029
/gene="KIF11"
/gene_synonym="EG5"
/gene_synonym="HKSP"
/gene_synonym="TRIP5"
/db_xref="GeneID:3832"
/db_xref="HGNC:HGNC:6388"
/db_xref="MIM:148760"
CDS 108..3278
/gene="KIF11"
/gene_synonym="EG5"
/gene_synonym="HKSP"
/gene_synonym="TRIP5"
/codon_start=1
/product="kinesin family member 11"
/protein_id="AAI36475.1"
/db_xref="GeneID:3832"
/db_xref="HGNC:HGNC:6388"
/db_xref="MIM:148760"
/translation="MASQPNSSAKKKEEKGKNIQVVVRCRPFNLAERKASAHSIVECD
PVRKEVSVRTGGLADKSSRKTYTFDMVFGASTKQIDVYRSVVCPILDEVIMGYNCTIF
AYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIPRTLHQIFEKLTDNGTEFSVKVSL
LEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVIIKGLEEITVHNKDEVYQILEKGA
AKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEELVKIGKLNLVDLAGSENIGRSG
AVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESKLTRILQDSLGGRTRTSIIA
TISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAA
REKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEELNRVTELFMDNKNELDQC
KSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTK
DVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTL
FGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQEL
INVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVADKIEDQKKELDGFLSIL
CNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMNLWTERFCALEEKC
ENIQKPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRNFNQEGTKLVEESV
KHSDKLNGNLEKISQETEQRCESLNTRTVYFSEQWVSSLNEREQELHNLLEVVSQCCE
ASSSDITEKSDGRKAAHEKQHNIFLDQMTIDEDKLIAQNLELNETIKIGLTKLNCFLE
QDLKLDIPTGTTPQRKSYLYPSTLVRTEPREHLLDQLKRKQPELLMMLNCSENNKEET
IPDVDVEEAVLGQYTEEPLSQEPSVDAGVDCSSIGGVPFFQHKKSHGKDKENRGINTL
ERSKVEETTEHLVTKSRLPLRAQINL"
BASE COUNT 1350 a 737 c 857 g 1085 t
ORIGIN
1 gcccgagagt accagggaga ctccggcccc tgtcggccgc caagcccctc cgcccctcac
61 agcgcccagg tccgcggccg ggccttgatt ttttggcggg gaccgtcatg gcgtcgcagc
121 caaattcgtc tgcgaagaag aaagaggaga aggggaagaa catccaggtg gtggtgagat
181 gcagaccatt taatttggca gagcggaaag ctagcgccca ttcaatagta gaatgtgatc
241 ctgtacgaaa agaagttagt gtacgaactg gaggattggc tgacaagagc tcaaggaaaa
301 catacacttt tgatatggtg tttggagcat ctactaaaca gattgatgtt taccgaagtg
361 ttgtttgtcc aattctggat gaagttatta tgggctataa ttgcactatc tttgcgtatg
421 gccaaactgg cactggaaaa acttttacaa tggaaggtga aaggtcacct aatgaagagt
481 atacctggga agaggatccc ttggctggta taattccacg tacccttcat caaatttttg
541 agaaacttac tgataatggt actgaatttt cagtcaaagt gtctctgttg gagatctata
601 atgaagagct ttttgatctt cttaatccat catctgatgt ttctgagaga ctacagatgt
661 ttgatgatcc ccgtaacaag agaggagtga taattaaagg tttagaagaa attacagtac
721 acaacaagga tgaagtctat caaattttag aaaagggggc agcaaaaagg acaactgcag
781 ctactctgat gaatgcatac tctagtcgtt cccactcagt tttctctgtt acaatacata
841 tgaaagaaac tacgattgat ggagaagagc ttgttaaaat cggaaagttg aacttggttg
901 atcttgcagg aagtgaaaac attggccgtt ctggagctgt tgataagaga gctcgggaag
961 ctggaaatat aaatcaatcc ctgttgactt tgggaagggt cattactgcc cttgtagaaa
1021 gaacacctca tgttccttat cgagaatcta aactaactag aatcctccag gattctcttg
1081 gagggcgtac aagaacatct ataattgcaa caatttctcc tgcatctctc aatcttgagg
1141 aaactctgag tacattggaa tatgctcata gagcaaagaa catattgaat aagcctgaag
1201 tgaatcagaa actcaccaaa aaagctctta ttaaggagta tacggaggag atagaacgtt
1261 taaaacgaga tcttgctgca gcccgtgaga aaaatggagt gtatatttct gaagaaaatt
1321 ttagagtcat gagtggaaaa ttaactgttc aagaagagca gattgtagaa ttgattgaaa
1381 aaattggtgc tgttgaggag gagctgaata gggttacaga gttgtttatg gataataaaa
1441 atgaacttga ccagtgtaaa tctgacctgc aaaataaaac acaagaactt gaaaccactc
1501 aaaaacattt gcaagaaact aaattacaac ttgttaaaga agaatatatc acatcagctt
1561 tggaaagtac tgaggagaaa cttcatgatg ctgccagcaa gctgcttaac acagttgaag
1621 aaactacaaa agatgtatct ggtctccatt ccaaactgga tcgtaagaag gcagttgacc
1681 aacacaatgc agaagctcag gatatttttg gcaaaaacct gaatagtctg tttaataata
1741 tggaagaatt aattaaggat ggcagctcaa agcaaaaggc catgctagaa gtacataaga
1801 ccttatttgg taatctgctg tcttccagtg tctctgcatt agataccatt actacagtag
1861 cacttggatc tctcacatct attccagaaa atgtgtctac tcatgtttct cagattttta
1921 atatgatact aaaagaacaa tcattagcag cagaaagtaa aactgtacta caggaattga
1981 ttaatgtact caagactgat cttctaagtt cactggaaat gattttatcc ccaactgtgg
2041 tgtctatact gaaaatcaat agtcaactaa agcatatttt caagacttca ttgacagtgg
2101 ccgataagat agaagatcaa aaaaaggaac tagatggctt tctcagtata ctgtgtaaca
2161 atctacatga actacaagaa aataccattt gttccttggt tgagtcacaa aagcaatgtg
2221 gaaacctaac tgaagacctg aagacaataa agcagaccca ttcccaggaa ctttgcaagt
2281 taatgaatct ttggacagag agattctgtg ctttggagga aaagtgtgaa aatatacaga
2341 aaccacttag tagtgtccag gaaaatatac agcagaaatc taaggatata gtcaacaaaa
2401 tgacttttca cagtcaaaaa ttttgtgctg attctgatgg cttctcacag gaactcagaa
2461 attttaacca agaaggtaca aaattggttg aagaatctgt gaaacactct gataaactca
2521 atggcaacct ggaaaaaata tctcaagaga ctgaacagag atgtgaatct ctgaacacaa
2581 gaacagttta tttttctgaa cagtgggtat cttccttaaa tgaaagggaa caggaacttc
2641 acaacttatt ggaggttgta agccaatgtt gtgaggcttc aagttcagac atcactgaga
2701 aatcagatgg acgtaaggca gctcatgaga aacagcataa catttttctt gatcagatga
2761 ctattgatga agataaattg atagcacaaa atctagaact taatgaaacc ataaaaattg
2821 gtttgactaa gcttaattgc tttctggaac aggatctgaa actggatatc ccaacaggta
2881 cgacaccaca gaggaaaagt tatttatacc catcaacact ggtaagaact gaaccacgtg
2941 aacatctcct tgatcagctg aaaaggaaac agcctgagct gttaatgatg ctaaactgtt
3001 cagaaaacaa caaagaagag acaattccgg atgtggatgt agaagaggca gttctggggc
3061 agtatactga agaacctcta agtcaagagc catctgtaga tgctggtgtg gattgttcat
3121 caattggcgg ggttccattt ttccagcata aaaaatcaca tggaaaagac aaagaaaaca
3181 gaggcattaa cacactggag aggtctaaag tggaagaaac tacagagcac ttggttacaa
3241 agagcagatt acctctgcga gcccagatca acctttaatt cacttggggg ttggcaattt
3301 tatttttaaa gaaaacttaa aaataaaacc tgaaacccca gaacttgagc cttgtgtata
3361 gattttaaaa gaatatatat atcagccggg cgcggtggct catgcctgta atcccagcac
3421 tttgggaggc tgaggcgggt ggattgcttg agcccaggag tttgagacca gcctggccaa
3481 cgtggcaaaa cctcgtctct gttaaaaatt agccgggcgt ggtggcacac tcctgtaatc
3541 ccagctactg gggaggctga ggcacgagaa tcacttgaac ccaggaagcg gggttgcagt
3601 gagccaaagg tacaccacta cactccagcc tgggcaacag agcaagactc ggtctcaaaa
3661 acaaaattta aaaaagatat aaggcagtac tgtaaattca gttgaatttt gatatctacc
3721 catttttctg tcatccctat agttcacttt gtattaaatt gggtttcatt tgggatttgc
3781 aatgtaaata cgtatttcta gttttcatat aaagtagttc ttttataaca aatgaaaagt
3841 atttttcttg tatattatta agtaatgaat atataagaac tgtactcttc tcagcttgag
3901 cttacatagg taaatatcac caacatctgt ccttagaaag gaccatctca tgtttttttt
3961 cttgctatga cttgtgtatt ttcttgcctc ctccctagac ttccctattt cgctttctcc
4021 tcggctcac
//