LOCUS BC136333 5158 bp mRNA linear HUM 18-MAR-2009
DEFINITION Homo sapiens CDC42 binding protein kinase alpha (DMPK-like), mRNA
(cDNA clone MGC:167943 IMAGE:9020320), complete cds.
ACCESSION BC136333
VERSION BC136333.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5158)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5158)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Ambion
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: LLDM Plate: 670 Row: d Column: 14
single stranded.
FEATURES Location/Qualifiers
source 1..5158
/db_xref="H-InvDB:HIT000500360"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:167943 IMAGE:9020320"
/tissue_type="Testicle, PCR rescued clones"
/clone_lib="NIH_MGC_382"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GAGGGAGC"
gene 1..5158
/gene="CDC42BPA"
/gene_synonym="MRCK"
/gene_synonym="MRCKA"
/gene_synonym="PK428"
/db_xref="GeneID:8476"
/db_xref="HGNC:HGNC:1737"
/db_xref="MIM:603412"
CDS 28..5127
/gene="CDC42BPA"
/gene_synonym="MRCK"
/gene_synonym="MRCKA"
/gene_synonym="PK428"
/codon_start=1
/product="CDC42BPA protein"
/protein_id="AAI36334.1"
/db_xref="GeneID:8476"
/db_xref="HGNC:HGNC:1737"
/db_xref="MIM:603412"
/translation="MSGEVRLRQLEQFILDGPAQTNGQCFSVETLLDILICLYDECNN
SPLRREKNILEYLEWAKPFTSKVKQMRLHREDFEILKVIGRGAFGEVAVVKLKNADKV
FAMKILNKWEMLKRAETACFREERDVLVNGDNKWITTLHYAFQDDNNLYLVMDYYVGG
DLLTLLSKFEDRLPEDMARFYLAEMVIAIDSVHQLHYVHRDIKPDNILMDMNGHIRLA
DFGSCLKLMEDGTVQSSVAVGTPDYISPEILQAMEDGKGRYGPECDWWSLGVCMYEML
YGETPFYAESLVETYGKIMNHKERFQFPAQVTDVSENAKDLIRRLICSREHRLGQNGI
EDFKKHPFFSGIDWDNIRNCEAPYIPEVSSPTDTSNFDVDDDCLKNSETMPPPTHTAF
SGHHLPFVGFTYTSSCVLSDRSCLRVTAGPTSLDLDVNVQRTLDNNLATEAYERRIKR
LEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTESSH
LEQQLEEANAVRQELDDAFRQIKAYEKQIKTLQQEREDLNKELVQASERLKNQSKELK
DAHCQRKLAMQEFMEINERLTELHTQKQKLARHVRDKEEEVDLVMQKVESLRQELRRT
ERAKKELEVHTEALAAEASKDRKLREQSEHYSKQLENELEGLKQKQISYSPGVCSIEH
QQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHDSEGQQLALNKEIMILK
DKLEKTRRESQSEREEFESEFKQQYEREKVLLTEENKKLTSELDKLTTLYENLSIHNQ
QLEEEVKDLADKKESVAHWEAQITEIIQWVSDEKDARGYLQALASKMTEELEALRNSS
LGTRATDMPWKMRRFAKLDMSARLELQSALDAEIRAKQAIQEELNKVKASNIITECKL
KDSEKKNLELLSEIEQLIKDTEELRSEKASKGRRTVDSTPLSVHTPTLRKKGCPGSTG
FPPKRKTHQFFVKSFTTPTKCHQCTSLMVGLIRQGCSCEVCGFSCHITCVNKAPTTCP
VPPEQTKGPLGIDPQKGIGTAYEGHVRIPKPAGVKKGWQRALAIVCDFKLFLYDIAEG
KASQPSVVISQVIDMRDEEFSVSSVLASDVIHASRKDIPCIFRVTASQLSASNNKCSI
LMLADTENEKNKWVGVLSELHKILKKNKFRDRSVYVPKEAYDSTLPLIKTTQAAAIID
HERIALGNEEGLFVVHVTKDEIIRVGDNKKIHQIELIPNDQLVAVISGRNRHVRLFPM
SALDGRETDFYKLSETKGCQTVTSGKVRHGALTCLCVAMKRQVLCYELFQSKTRHRKF
KEIQVPYNVQWMAIFSEQLCVGFQSGFLRYPLNGEGNPYSMLHSNDHTLSFIAHQPMD
AICAVEISSKEYLLCFNSIGIYTDCQGRRSRQQELMWPANPSSCCYNAPYLSVYSENA
VDIFDVNSMEWIQTLPLKKVRPLNNEGSLNLLGLETIRLIYFKNKMAEGDELVVPETS
DNSRKQMVRNINNKRRYSFRVPEEERMQQRREMLRDPEMRNKLISNPTNFNHIAHMGP
GDGIQILKDLPMNPRPQESRTVFSGSVSIPSITKSRPEPGRSMSASSGLSARSSAQNG
SALKREFSGGSYSAKRQPMPSPSEGSLSSGGMDQGSDAPARDFDGEDSDSPRHSTASN
SSNLSSPPSPVSPRKTKSLSLESTDRGSWDP"
BASE COUNT 1753 a 975 c 1175 g 1255 t
ORIGIN
1 ggaaaaccag cagaaatcga agcaaacatg tctggagaag tgcgtttgag gcagttggag
61 cagtttattt tggacgggcc cgctcagacc aatgggcagt gcttcagtgt ggagacatta
121 ctggatatac tcatctgcct ttatgatgaa tgcaataatt ctccattgag aagagagaag
181 aacattctcg aatacctaga atgggctaaa ccatttactt ctaaagtgaa acaaatgcga
241 ttacatagag aagactttga aatattaaag gtgattggtc gaggagcttt tggggaggtt
301 gctgtagtaa aactaaaaaa tgcagataaa gtgtttgcca tgaaaatatt gaataaatgg
361 gaaatgctga aaagagctga gacagcatgt tttcgtgaag aaagggatgt attagtgaat
421 ggagacaata aatggattac aaccttgcac tatgctttcc aggatgacaa taacttatac
481 ctggttatgg attattatgt tggtggggat ttgcttactc tactcagcaa atttgaagat
541 agattgcctg aagatatggc tagattttac ttggctgaga tggtgatagc aattgactca
601 gttcatcagc tacattatgt acacagagac attaaacctg acaatatact gatggatatg
661 aatggacata ttcggttagc agattttggt tcttgtctga agctgatgga agatggaacg
721 gttcagtcct cagtggctgt aggaactcca gattatatct ctcctgaaat ccttcaagcc
781 atggaagatg gaaaagggag atatggacct gaatgtgact ggtggtcttt gggggtctgt
841 atgtatgaaa tgctttacgg agaaacacca ttttatgcag aatcgctggt ggagacatac
901 ggaaaaatca tgaaccacaa agagaggttt cagtttccag cccaagtgac tgatgtgtct
961 gaaaatgcta aggatcttat tcgaaggctc atttgtagca gagaacatcg acttggtcaa
1021 aatggaatag aagactttaa gaaacaccca tttttcagtg gaattgattg ggataatatt
1081 cggaactgtg aagcacctta tattccagaa gttagtagcc caacagatac atcgaatttt
1141 gatgtagatg atgattgttt aaaaaattct gaaacgatgc ccccaccaac acatactgca
1201 ttttctggcc accatctgcc atttgttggt tttacatata ctagtagctg tgtactttct
1261 gatcggagct gtttaagagt tacggctggt cccacctcac tggatcttga tgttaatgtt
1321 cagaggactc tagacaacaa cttagcaact gaagcttatg aaagaagaat taagcgcctt
1381 gagcaagaaa aacttgaact cagtagaaaa cttcaagagt caacacagac tgtccaagct
1441 ctgcagtatt caactgttga tggtccacta acagcaagca aagatttaga aataaaaaac
1501 ttaaaagaag aaattgaaaa actaagaaaa caagtaacag aatcaagtca tttggaacag
1561 caacttgaag aagctaatgc tgtgaggcaa gaactagatg atgcttttag acaaatcaag
1621 gcttatgaaa aacaaatcaa aacgttacaa caagaaagag aagatctaaa taaggaacta
1681 gtccaggcta gtgagcgatt aaaaaaccaa tccaaagagc tgaaagacgc acactgtcag
1741 aggaaactgg ccatgcagga attcatggag atcaatgagc ggctaacaga attgcacacc
1801 caaaaacaga aacttgctcg ccatgtccga gataaggaag aagaggtgga cctggtgatg
1861 caaaaagttg aaagcttaag gcaagaactg cgcagaacag aaagagccaa aaaagagctg
1921 gaagttcata cagaagctct agctgctgaa gcatctaaag acaggaagct acgtgaacag
1981 agtgagcact attctaagca actggaaaat gaattggagg gactgaagca aaaacaaatt
2041 agttactcac caggagtatg cagcatagaa catcagcaag agataaccaa actaaagact
2101 gatttggaaa agaaaagtat cttttatgaa gaagaattat ctaaaagaga aggaatacat
2161 gcaaatgaaa taaaaaatct taagaaagaa ctgcatgatt cagaaggtca gcaacttgct
2221 ctcaacaaag aaattatgat tttaaaagac aaattggaaa aaaccagaag agaaagtcaa
2281 agtgaaaggg aggaatttga aagtgagttc aaacaacaat atgaacgaga aaaagtgttg
2341 ttaactgaag aaaataaaaa gctgacgagt gaacttgata agcttactac tttgtatgag
2401 aacttaagta tacacaacca gcagttagaa gaagaggtta aagatctagc agacaagaaa
2461 gaatcagttg cacattggga agcccaaatc acagaaataa ttcagtgggt cagcgatgaa
2521 aaggatgcac gagggtatct tcaggcctta gcttctaaaa tgactgaaga attggaggca
2581 ttaagaaatt ccagcttggg tacacgagca acagatatgc cctggaaaat gcgtcgtttt
2641 gcgaaactgg atatgtcagc tagactggag ttgcagtcgg ctctggatgc agaaataaga
2701 gccaaacagg ccatccaaga agagttgaat aaagttaaag catctaatat cataacagaa
2761 tgtaaactaa aagattcaga gaagaagaac ttggaactac tctcagaaat cgaacagctg
2821 ataaaggaca ctgaagagct tagatctgaa aaggctagca aaggcagacg tactgtagac
2881 tccactccac tttcagttca cacaccaacc ttaaggaaaa aaggatgtcc tggttcaact
2941 ggctttccac ctaagcgcaa gactcaccag ttttttgtaa aatcttttac tactcctacc
3001 aagtgtcatc agtgtacctc cttgatggtg ggtttaataa gacagggctg ttcatgtgaa
3061 gtgtgtggat tctcatgcca tataacttgt gtaaacaaag ctccaaccac ttgtccagtt
3121 cctcctgaac agacaaaagg tcccctgggt atagatcctc agaaaggaat aggaacagca
3181 tatgaaggtc atgtcaggat tcctaagcca gctggagtga agaaagggtg gcagagagca
3241 ctggctatag tgtgtgactt caaactcttt ctgtacgata ttgctgaagg aaaagcatct
3301 cagcccagtg ttgtcattag tcaagtgatt gacatgaggg atgaagaatt ttctgtgagt
3361 tcagtcttgg cttctgatgt tatccatgca agtcggaaag atataccctg tatatttagg
3421 gtcacagctt cccagctctc agcatctaat aacaaatgtt caatcctgat gctagcagac
3481 actgagaatg agaagaataa gtgggtggga gtgctgagtg aattgcacaa gattttgaag
3541 aaaaacaaat tcagagaccg ctcagtctat gttcccaaag aggcttatga cagcactcta
3601 cccctcatta aaacaaccca ggcagccgca atcatagatc atgaaagaat tgctttggga
3661 aacgaagaag ggttatttgt tgtacatgtc accaaagatg aaattattag agttggtgac
3721 aataagaaga ttcatcagat tgaactcatt ccaaatgatc agcttgttgc tgtgatctca
3781 ggacgaaatc gtcatgtacg actttttcct atgtcagcat tggatgggcg agagaccgat
3841 ttttacaagc tgtcagaaac taaagggtgt caaaccgtaa cttctggaaa ggtgcgccat
3901 ggagctctca catgcctgtg tgtggctatg aaaaggcagg tcctctgtta tgaactattt
3961 cagagcaaga cccgtcacag aaaatttaaa gaaattcaag tcccatataa tgtccagtgg
4021 atggcaatct tcagtgaaca actctgtgtg ggattccagt caggatttct aagatacccc
4081 ttgaatggag aaggaaatcc atacagtatg ctccattcaa atgaccatac actatcattt
4141 attgcacatc aaccaatgga tgctatctgc gcagttgaga tctccagtaa agaatatctg
4201 ctgtgtttta acagcattgg gatatacact gactgccagg gccgaagatc tagacaacag
4261 gaattgatgt ggccagcaaa tccttcctct tgttgttaca atgcaccata tctctcggtg
4321 tacagtgaaa atgcagttga tatctttgat gtgaactcca tggaatggat tcagactctt
4381 cctctcaaaa aggttcgacc cttaaacaat gaaggatcat taaatctttt agggttggag
4441 accattagat taatatattt caaaaataag atggcagaag gggacgaact ggtagtacct
4501 gaaacatcag ataatagtcg gaaacaaatg gttagaaaca ttaacaataa gcggcgttat
4561 tccttcagag tcccagaaga ggaaaggatg cagcagagga gggaaatgct acgagatcca
4621 gaaatgagaa ataaattaat ttctaatcca actaatttta atcacatagc acacatgggt
4681 cctggagatg gaatacagat cctgaaagat ctgcccatga accctcggcc tcaggaaagt
4741 cggacagtat tcagtggctc agtcagtatt ccatctatca ccaaatcccg ccctgagcca
4801 ggccgctcca tgagtgctag cagtggcttg tcagcaaggt catccgcaca gaatggcagc
4861 gcattaaaga gggaattctc tggaggaagc tacagtgcca agcggcagcc catgccctcc
4921 ccgtcagagg gctctttgtc ctctggaggc atggaccaag gaagtgatgc cccagcgagg
4981 gactttgacg gagaggactc tgactctccg aggcattcca cagcttccaa cagttccaac
5041 ctaagcagcc ccccaagccc agtttcaccc cgaaaaacca agagcctctc cctggagagc
5101 actgaccgcg ggagctggga cccgtgagct gcctcagcac tgggacctct cgctctcc
//