LOCUS BC136290 3425 bp mRNA linear HUM 11-FEB-2009
DEFINITION Homo sapiens protein phosphatase 1E (PP2C domain containing), mRNA
(cDNA clone MGC:167900 IMAGE:9020277), complete cds.
ACCESSION BC136290
VERSION BC136290.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3425)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3425)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 13 Row: G Column: 3
single stranded.
FEATURES Location/Qualifiers
source 1..3425
/db_xref="H-InvDB:HIT000500321"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:167900 IMAGE:9020277"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: ATTTCTCC"
gene 1..3425
/gene="PPM1E"
/gene_synonym="POPX1"
/gene_synonym="PP2CH"
/db_xref="GeneID:22843"
/db_xref="HGNC:HGNC:19322"
CDS 70..2343
/gene="PPM1E"
/gene_synonym="POPX1"
/gene_synonym="PP2CH"
/codon_start=1
/product="protein phosphatase 1E (PP2C domain containing)"
/protein_id="AAI36291.1"
/db_xref="GeneID:22843"
/db_xref="HGNC:HGNC:19322"
/translation="MAGCIPEEKTYRRFLELFLGEFRGPCGGGEPEPEPEPEPEPEPE
PESEPEPEPELVEAEAAEASVEEPGEEAATVAATEEGDQEQDPEPEEEAAVEGEEEEE
GAATAAAAPGHSAVPPPPPQLPPLPPLPRPLSERITREEVEGESLDLCLQQLYKYNCP
SFLAAALARATSDEVLQSDLSAHYIPKETDGTEGTVEIETVKLARSVFSKLHEICCSW
VKDFPLRRRPQLYYETSIHAIKNMRRKMEDKHVCIPDFNMLFNLEDQEEQAYFAVFDG
HGGVDAAIYASIHLHVNLVRQEMFPHDPAEALCRAFRVTDERFVQKAARESLRCGTTG
VVTFIRGNMLHVAWVGDSQVMLVRKGQAVELMKPHKPDREDEKQRIEALGGCVVWFGA
WRVNGSLSVSRAIGDAEHKPYICGDADSASTVLDGTEDYLILACDGFYDTVNPDEAVK
VVSDHLKENNGDSSMVAHKLVASARDAGSSDNITVIVVFLRDMNKAVNVSEESDWTEN
SFQGGQEDGGDDKENHGECKRPWPQHQCSAPADLGYDGRVDSFTDRTSLSPGSQINVL
EDPGYLDLTQIEASKPHSAQFLLPVEMFGPGAPKKANLINELMMEKKSVQSSLPEWSG
AGEFPTAFNLGSTGEQIYRMQSLSPVCSGLENEQFKSPGNRVSRLSHLRHHYSKKWHR
FRFNPKFYSFLSAQEPSHKIGTSLSSLTGSGKRNRIRSSLPWRQNSWKGYSENMRKLR
KTHDIPCPDLPWSYKIE"
BASE COUNT 951 a 768 c 857 g 849 t
ORIGIN
1 aagcagcccc ttacccttcc tgggcttccc ccaacccctt tcccggtctg ccctggggca
61 tgagcagcga tggccggctg catccctgag gagaaaactt accggcgctt cctggagcta
121 ttcctgggcg agtttcgcgg accgtgcggc ggcggcgagc cggagccgga acccgaaccc
181 gaacccgaac ccgaacccga acccgagtcc gagcccgagc ccgaacctga actggtagaa
241 gctgaggcgg ccgaggcttc ggtagaggaa cccggggagg aggcggccac ggtagccgcg
301 acggaggagg gggaccagga gcaagacccg gagcccgagg aggaggcggc ggttgagggt
361 gaggaggagg aggagggcgc ggcgacggcg gcggcagccc cggggcactc ggccgtgccg
421 ccgccgccgc cccagctgcc gcctttgccc ccgctcccgc gaccgctgtc agagcgcatc
481 acccgcgagg aggtggaggg cgaaagcctg gacctgtgcc tgcagcagct ctacaaatat
541 aattgccctt cctttttggc tgctgcttta gccagagcca catcagatga agtccttcag
601 agtgatcttt ctgcacatta tatcccaaag gaaacggatg gcacagaagg gactgtggag
661 attgagacag tgaaattggc ccgttctgtc ttcagcaaac tacacgagat ttgctgcagc
721 tgggtgaaag acttccccct ccgcaggaga ccccagcttt attatgagac atcaatccat
781 gccatcaaaa acatgcgcag gaaaatggag gacaaacatg tctgcattcc tgactttaat
841 atgctcttca acctagagga ccaggaagaa caagcttact ttgcagtgtt tgatggccat
901 gggggagtag atgctgctat ttatgcctcc attcacctcc acgttaactt agtccgccag
961 gagatgttcc cccatgatcc tgctgaggcc ctgtgcaggg ccttccgggt cactgatgag
1021 cggtttgtgc agaaagcagc cagggagagc ttaagatgtg ggaccacagg agtggtgact
1081 ttcatcagag gcaacatgct acatgtggcc tgggtgggtg attcccaggt tatgcttgtg
1141 agaaagggcc aagctgttga actaatgaag ccacacaaac cagacagaga ggatgaaaag
1201 cagagaattg aggcccttgg aggttgcgta gtctggtttg gtgcctggag ggtgaatgga
1261 agtctgtcgg tttccagagc tattggagat gctgaacata agccatatat ctgtggggat
1321 gcagattctg cctccactgt tctggatggg accgaagact acctcattct ggcctgtgat
1381 ggcttctatg acaccgtgaa ccctgatgag gcagtgaaag ttgtgtccga ccacctgaaa
1441 gagaataatg gagacagcag catggttgcc cacaaattag tggcatcagc tcgtgatgct
1501 gggtcaagtg ataacatcac ggttattgtg gtattcctga gggacatgaa caaagctgta
1561 aatgttagtg aggaatcaga ttggacagag aactcttttc aaggagggca agaagatggt
1621 ggggatgata aggagaatca tggagagtgc aaacgccctt ggcctcagca ccagtgctca
1681 gcaccagccg acctaggcta tgatgggcgt gtggattcat tcactgatag aactagcctg
1741 agcccagggt cccaaatcaa cgtgctggaa gacccaggct acctagatct cacacaaata
1801 gaagcaagca aacctcacag tgcccagttt ttgctaccag ttgagatgtt tggtcctggt
1861 gcaccaaaga aagcaaatct tattaatgag ttaatgatgg agaaaaaatc agttcagtca
1921 tcattgcctg aatggagtgg tgctggagag tttcccactg ctttcaattt gggttcaaca
1981 ggggagcaga tatacagaat gcagagcttg tctcctgtct gttcagggtt ggaaaatgaa
2041 cagttcaaat ccccgggaaa cagagtttct agattgtctc atttacgcca ccactactca
2101 aagaagtggc acagattcag gtttaatcca aagttttatt catttctctc tgctcaagag
2161 ccttcccaca aaataggcac tagcctgtcc tcacttactg gaagtgggaa gagaaatagg
2221 ataagaagtt ctctgccatg gaggcaaaat agttggaaag ggtacagtga aaacatgagg
2281 aagctcagaa agactcatga tattccatgc ccagatcttc cttggagcta taaaatagaa
2341 taatttttct ttcaagtagg ttagctagct ctcccccaat aaaaatacca ctatcagagt
2401 agaaacaagg tagacatttc taaaacatat gtgcttcatt atgaatccat ggatggctca
2461 attcttaaat gtaaatagat ctctaggaaa ctcaaagtac agtgttttca atctaaaaag
2521 aagtattggc agtttcactt gcaaaattac acagctggtc cctgtgatgt gtctcgacac
2581 caatacacaa cccccttccc accatccttc atgtcactag atacacaacc cccttcccac
2641 catcccttca gtcactagtg aaagctttca agttagttat ttcagtcagg atatacagtg
2701 ttgaaatctc aatgcagttg aaatctggtc tgatgtgcct aatttatctg tggaaaattt
2761 aatgctgaat tacatttggt tgggaaatgt ccctcaaaat cctgggcact atgaaggaac
2821 cccctgcccc ctcacctttt tgggtaggta aaagactaaa agccatatgg attttaactg
2881 ataacaatga aagtggtaaa tcagtgtaaa agtgtcatat tctcagactt gtgaggcggt
2941 ttatagtcag aaagatttac ggattttttt cctgtaacat aaaagattgt gaactttttt
3001 taattaaaaa atatttccta gggctgtagt tatttgggag tttcataacc tgttatggtg
3061 cttttggtgg aatttttatt atttagcatt ttaggagacc gctgtcaact ggttttaatc
3121 tatgatgcta atgtgttttc cactgtaccc tcatctcagg aataaaactg ctttaacgga
3181 gatgatgtca ggtacaaata cactatagag tcaaaatacc atttacaaag aaaatcaaaa
3241 gcatttctat attttgtctt tttttagttc agacagcaaa ggcatgtact actataaaat
3301 acaaagtgat tttagagaat gaaaaatgct acttttatct tctctaaaat tatttccccc
3361 aaggtagtga agtaattgga atgaaggagg ctgaaagtat tgtctaaagt gagcccagag
3421 gccac
//