LOCUS BC133707 3061 bp mRNA linear HUM 06-MAR-2007
DEFINITION Homo sapiens amiloride-sensitive cation channel 2, neuronal, mRNA
(cDNA clone MGC:158889 IMAGE:40008524), complete cds.
ACCESSION BC133707
VERSION BC133707.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3061)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3061)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-MAR-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCG Plate: 14 Row: b Column: 7.
FEATURES Location/Qualifiers
source 1..3061
/db_xref="H-InvDB:HIT000391131"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:158889 IMAGE:40008524"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: AGCTTTTC sequenced from
the forward primer"
gene 1..3061
/gene="ACCN2"
/gene_synonym="ASIC"
/gene_synonym="ASIC1A"
/gene_synonym="BNaC2"
/gene_synonym="hBNaC2"
/db_xref="GeneID:41"
/db_xref="HGNC:HGNC:100"
/db_xref="MIM:602866"
CDS 25..1611
/gene="ACCN2"
/gene_synonym="ASIC"
/gene_synonym="ASIC1A"
/gene_synonym="BNaC2"
/gene_synonym="hBNaC2"
/codon_start=1
/product="amiloride-sensitive cation channel 2, neuronal"
/protein_id="AAI33708.1"
/db_xref="GeneID:41"
/db_xref="HGNC:HGNC:100"
/db_xref="MIM:602866"
/translation="MELKAEEEEVGGVQPVSIQAFASSSTLHGLAHIFSYERLSLKRA
LWALCFLGSLAVLLCVCTERVQYYFHYHHVTKLDEVAASQLTFPAVTLCNLNEFRFSQ
VSKNDLYHAGELLALLNNRYEIPDTQMADEKQLEILQDKANFRSFKPKPFNMREFYDR
AGHDIRDMLLSCHFRGEVCSAEDFKVVFTRYGKCYTFNSGRDGRPRLKTMKGGTGNGL
EIMLDIQQDEYLPVWGETDETSFEAGIKVQIHSQDEPPFIDQLGFGVAPGFQTFVACQ
EQRLIYLPPPWGTCKAVTMDSDLDFFDSYSITACRIDCETRYLVENCNCRMVHMPGDA
PYCTPEQYKECADPALDFLVEKDQEYCVCEMPCNLTRYGKELSMVKIPSKASAKYLAK
KFNKSEQYIGENILVLDIFFEVLNYETIEQKKAYEIAGLLGDIGGQMGLFIGASILTV
LELFDYAYEVIKHKLCRRGKCQKEAKRSSADKGVALSLDDVKRHNPCESLRGHPAGMT
YAANILPHHPARGTFEDFTC"
BASE COUNT 679 a 928 c 796 g 658 t
ORIGIN
1 cccctcagga tcccctcaac aaggatggaa ctgaaggccg aggaggagga ggtgggtggc
61 gtccagccgg tgagcatcca ggccttcgcc agcagctcca cactgcacgg cctggcccac
121 atcttctcct acgagcggct gtctctgaag cgggcactgt gggccctgtg cttcctgggc
181 tcgctggctg tgctgctgtg tgtgtgcacg gagcgtgtgc agtactactt ccactaccac
241 catgtcacca agctcgacga ggtggctgcc tctcagctta ccttccctgc tgtcacgctg
301 tgcaacctca acgagttccg ctttagccaa gtctccaaga atgacctgta tcatgctggg
361 gagctgctgg ccctgctcaa caacaggtat gagataccag acacacagat ggcagatgaa
421 aagcagctgg agatactgca ggacaaagcc aacttccgca gcttcaaacc caaacccttc
481 aacatgcgtg agttctacga ccgagctggg cacgacattc gagacatgct gctctcctgc
541 cacttccggg gggaggtctg cagcgctgaa gacttcaagg tggtcttcac acgctatgga
601 aagtgctaca cgttcaactc gggccgagat gggcggccgc ggctgaagac catgaagggt
661 gggacgggca atgggctgga aatcatgctg gacatccagc aggacgagta cctgcctgtg
721 tggggggaga ctgacgagac gtccttcgaa gcaggcatca aagtgcagat ccatagtcag
781 gatgaacctc ctttcatcga ccagctgggc tttggcgtgg ccccaggctt ccagaccttt
841 gtggcctgcc aggagcagcg gctcatctac ctgcccccac cctggggcac ctgcaaagct
901 gttaccatgg actcggattt ggatttcttc gactcctaca gcatcactgc ctgccgcatc
961 gactgtgaga cgcgctacct ggtggagaac tgcaactgcc gcatggtgca catgccaggg
1021 gatgccccat actgtactcc agagcagtac aaggagtgtg cagatcctgc tctggacttc
1081 ctggtggaga aggaccagga gtactgcgtg tgtgaaatgc cttgcaacct gacccgctat
1141 ggcaaagagc tgtccatggt caagatcccc agcaaagcct cagccaagta cctggccaag
1201 aagttcaaca aatctgagca atacataggg gagaacatcc tggtgctgga cattttcttt
1261 gaagtcctca actatgagac cattgaacag aagaaggcct atgagattgc agggctcctg
1321 ggtgacatcg ggggccagat ggggctgttc atcggggcca gcatcctcac ggtgctggag
1381 ctctttgact acgcctacga ggtcattaag cacaagctgt gccgacgagg aaaatgccag
1441 aaggaggcca aaaggagcag tgcggacaag ggcgtggccc tcagcctgga cgacgtcaaa
1501 agacacaacc cgtgcgagag ccttcggggc caccctgccg ggatgacata cgctgccaac
1561 atcctacctc accatccggc ccgaggcacg ttcgaggact ttacctgctg agccccgcag
1621 gccgctgaac caaaggccta gatggggagg actaggagag cgagggggcc cccagctgcc
1681 tcctcacatc tgccctgggg actccccaca ctccggggca gatctttcct cttgtctgtg
1741 gtaaggaagg agtcttgacc atagagtcct ctctctgcct ctatcccatt ctttttacat
1801 ttaacaaaac taatctaaaa aagaactaaa aagggagaac ggggcaaggg acctcaggct
1861 gcccctctct cctccatgct gcctccccta gctcccagcc tgaattctgt ctatctagct
1921 gtctgccatc tgagtgtcca tctacattct gctgccacca gtcaccaaag gcccttccca
1981 gtgaggggtg gaagggatct ctggggtctg gaatttggcc ccaaaccaga gaatgtacct
2041 taagggggag ggctagtgtg ggggagggag gcttccccag ccttaagaga ccctctcagc
2101 ccagtgactg tccccaaacc caagtctcct ggcaggaact aaaacctcag ccccactctc
2161 tcacaccatg tggaatctcg tgggggtcgg ggatcccctt aagaagtggt aatggggaca
2221 agatgcggcc ctggtgctgt aggctacatc ctgataccta taagttcacc cccaccccac
2281 agctgctgga gagaaatccc aagaggcagc ccttcctcac catcccatta aagacctggc
2341 tggttagcgt ccagctcagg gagaagggcg ctagtgccta acctcactgg tccctctccc
2401 ggaggccctt gtagagggcc acgtccataa attttcttat ggaactctcc cacatcctct
2461 tccccaactt catttgcttc tctcaacaac ctcatctgca ttttctattt ctatatgata
2521 cagactctat attgctatat ctctgtatat actttcccag ccctgtctgt ctccacccca
2581 tcccctcttg tctctgagaa ccattctccc accccaagtt ccaccttcta tgtttctact
2641 ccctccctgg tctctgaatg ccttcgcctg tataaagagt tggactctct cccctggtgt
2701 ctgtactgtg tacacacatc cctctgagaa gcacaaggag acgacacgcg cattgtaacc
2761 tttgcactgt ctcagtggcg acaaaggaag ctgtgaatca caagctctgc ctctttctgg
2821 cctcaccctc tcccccaacc cgggcaccct cggccctccc tgcagcctta acattctctt
2881 cccctgctcc tcctatccca ttgccctctg cccagctgac agtggcatcc ccagggaagg
2941 ggttgctgta gagatagccc ccacccaggg gatggaggtc taccctggac actaagccaa
3001 gtgtgtcaga gacagaaggg agctggggat tggcgactcc tgaagttggg gcagtgggat
3061 g
//