LOCUS BC132874 4710 bp mRNA linear HUM 06-DEC-2007
DEFINITION Homo sapiens SLIT-ROBO Rho GTPase activating protein 2, mRNA (cDNA
clone MGC:164505 IMAGE:40146896), complete cds.
ACCESSION BC132874
VERSION BC132874.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4710)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4710)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 9 Row: I Column: 16.
FEATURES Location/Qualifiers
source 1..4710
/db_xref="H-InvDB:HIT000390927"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:164505 IMAGE:40146896"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_363"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: CTGTATTA"
gene 1..4710
/gene="SRGAP2"
/gene_synonym="srGAP3"
/db_xref="GeneID:23380"
/db_xref="HGNC:HGNC:19751"
/db_xref="MIM:606524"
CDS 71..3286
/gene="SRGAP2"
/gene_synonym="srGAP3"
/codon_start=1
/product="SLIT-ROBO Rho GTPase activating protein 2"
/protein_id="AAI32875.1"
/db_xref="GeneID:23380"
/db_xref="HGNC:HGNC:19751"
/db_xref="MIM:606524"
/translation="MTSPAKFKKDKEIIAEYDTQVKEIRAQLTEQMKCLDQQCELRVQ
LLQDLQDFFRKKAEIEMDYSRNLEKLAERFLAKTRSTKDQQFKKDQNVLSPVNCWNLL
LNQVKRESRDHTTLSDIYLNNIIPRFVQVSEDSGRLFKKSKEVGQQLQDDLMKVLNEL
YSVMKTYHMYNADSISAQSKLKEAEKQEEKQIGKSVKQEDRQTPRSPDSTANVRIEEK
HVRRSSVKKIEKMKEKRQAKYTENKLKAIKARNEYLLALEATNASVFKYYIHDLSDLI
DQCCDLGYHASLNRALRTFLSAELNLEQSKHEGLDAIENAVENLDATSDKQRLMEMYN
NVFCPPMKFEFQPHMGDMASQLCAQQPVQSELVQRCQQLQSRLSTLKIENEEVKKTME
ATLQTIQDIVTVEDFDVSDCFQYSNSMESVKSTVSETFMSKPSIAKRRANQQETEQFY
FTKMKEYLEGRNLITKLQAKHDLLQKTLGESQRTDCSLARRSSTVRKQDSSQAIPLVV
ESCIRFISRHGLQHEGIFRVSGSQVEVNDIKNAFERGEDPLAGDQNDHDMDSIAGVLK
LYFRGLEHPLFPKDIFHDLMACVTMDNLQERALHIRKVLLVLPKTTLIIMRYLFAFLN
HLSQFSEENMMDPYNLAICFGPSLMSVPEGHDQVSCQAHVNELIKTIIIQHENIFPSP
RELEGPVYSRGGSMEDYCDSPHGETTSVEDSTQDVTAEHHTSDDECEPIEAIAKFDYV
GRTARELSFKKGASLLLYQRASDDWWEGRHNGIDGLIPHQYIVVQDTEDGVVERSSPK
SEIEVISEPPEEKVTARAGASCPSGGHVADIYLANINKQRKRPESGSIRKTFRSDSHG
LSSSLTDSSSPGVGASCRPSSQPIMSQSLPKEGPDKCSISGHGSLNSISRHSSLKNRL
DSPQIRKTATAGRSKSFNNHRPMDPEVIAQDIEATMNSALNELRELERQSSVKHTPDV
VLDTLEPLKTSPVVAPTSEPSSPLHTQLLKDPEPAFQRSASTAGDIACAFRPVKSVKM
AAPVKPPATRPKPTVFPKTNATSPGVNSSTSPQSTDKSCTV"
BASE COUNT 1271 a 1236 c 1110 g 1093 t
ORIGIN
1 gacgcgtggg ttggattttt tccgtggatc tatcaattca caattcgaat ttggaagaaa
61 gaaggaaaac atgacgtctc cagccaaatt caaaaaggat aaggagatca tagcagagta
121 cgatactcag gtcaaagaga tccgtgctca gctcacagag cagatgaaat gcctggacca
181 gcagtgtgag cttcgggtgc aactgttgca ggacctccag gacttcttcc gaaagaaggc
241 agagattgag atggactact cccgcaacct ggagaagctg gcagaacgct tcctggccaa
301 gacacgcagc accaaggacc agcaattcaa gaaggatcag aatgttctct ctccagtcaa
361 ctgctggaat ctcctcttaa accaggtgaa gcgggaaagc agggaccata ccaccctgag
421 tgacatctac ctgaataata tcattcctcg atttgtacaa gtcagcgagg actcaggaag
481 actctttaaa aagagtaaag aagtcggcca gcagctccaa gatgatttga tgaaggtcct
541 gaacgagctc tactcggtga tgaagacata tcacatgtac aatgccgaca gcatcagtgc
601 tcagagcaaa ctaaaggagg cggagaagca ggaggagaag caaattggta aatcggtaaa
661 gcaggaggac cggcagaccc cacgctcccc tgactccacg gccaacgttc gcattgagga
721 gaaacatgtc cggaggagct cagtgaagaa gattgagaag atgaaggaga agcgtcaagc
781 caagtacacg gagaataagc tgaaggccat caaagcccgg aatgagtact tgctggcttt
841 ggaggcaacc aatgcatctg tcttcaagta ctacatccat gacctatctg accttattga
901 tcagtgttgt gacttaggct accatgcaag tctgaaccgg gctctacgca ccttcctctc
961 tgctgagtta aacctggaac agtcgaagca tgagggtctg gatgccatcg agaatgcagt
1021 agaaaacctg gatgccacca gtgacaagca gcgcctcatg gagatgtaca acaacgtctt
1081 ctgcccccct atgaagtttg agtttcagcc ccacatgggg gatatggctt cccagctctg
1141 tgcccagcag cctgtccaga gtgagctggt acagagatgc caacaactgc agtctcgctt
1201 atccactcta aagattgaaa acgaagaggt aaagaagaca atggaggcca ccctgcaaac
1261 catccaggac attgtgactg tcgaggactt tgatgtgtct gactgcttcc agtacagcaa
1321 ctccatggag tccgtcaagt ccacggtctc tgaaaccttc atgagcaagc ccagcattgc
1381 taagaggaga gccaaccagc aagagacaga gcagttttat ttcacaaaaa tgaaagagta
1441 cctggagggc aggaacctca tcaccaagtt acaagccaag catgaccttc tgcagaaaac
1501 cctgggagaa agtcagcgga cagattgcag tctagccagg cgcagctcaa ctgtgaggaa
1561 acaggactcc agccaggcaa ttcctctagt ggtggaaagc tgtatccggt ttatcagcag
1621 acacggacta cagcatgaag gaattttccg ggtgtcagga tcccaggtgg aagtgaatga
1681 catcaaaaat gcctttgaga gaggagagga ccccctggct ggggaccaga acgaccatga
1741 catggattcc atagctggtg tcctgaagct ttacttccgg gggctggaac accctctctt
1801 ccccaaggac atctttcatg acctgatggc ctgcgtcaca atggacaacc tgcaggagag
1861 agctctgcac atccggaaag tcctcctagt cctgcccaaa accactctga ttatcatgag
1921 atacctcttt gccttcctca atcatttatc acagttcagt gaagagaaca tgatggaccc
1981 ctacaacctc gccatctgct tcgggccctc gctaatgtca gtgccagagg gccacgacca
2041 ggtgtcctgc caagcccacg tgaatgagct gatcaaaacc atcatcatcc agcatgagaa
2101 catcttccca agccccaggg agctggaggg ccctgtctac agcagaggag gaagcatgga
2161 ggattactgt gatagccctc atggagagac tacctcggtt gaagactcaa cccaggatgt
2221 gaccgcagag caccacacga gcgatgacga atgtgagccc atcgaggcca ttgccaagtt
2281 tgactacgtg ggccggacag cccgagagct gtcctttaag aagggagcat ccctgctgct
2341 ttaccagcgg gcttccgacg actggtggga aggccggcac aatggcatcg acggactcat
2401 cccccatcag tacatcgtgg tccaagacac cgaggacggt gtcgtggaga ggtccagccc
2461 caagtctgag attgaggtca tttctgagcc acctgaagaa aaggtgacag ccagagcggg
2521 ggccagctgt cccagtgggg gtcatgtagc cgatatttat cttgcaaaca tcaacaagca
2581 aaggaagcgt ccagaatctg ggagcatccg gaaaactttt cggagtgaca gccatgggct
2641 gagcagttcc ctgactgact cctcctcccc aggggtgggg gctagctgcc gcccatcctc
2701 ccagcccatc atgagccaga gcctccccaa agaagggcca gataagtgtt ccatcagtgg
2761 gcacgggagc ctcaactcca tcagccgcca ctcatccctg aagaatcggc tggatagtcc
2821 acagatccgg aagactgcca cagcgggaag gtcaaaaagc ttcaataacc atcggcccat
2881 ggaccctgag gtcattgctc aggatattga ggcaacaatg aactcggccc tgaatgagct
2941 acgggaacta gaacggcaga gcagtgtcaa acacacccct gacgtggttc tggacacctt
3001 ggagcccctc aaaacctccc cagtggtggc ccccacgtca gagccctcca gccctctgca
3061 cacccagctc ctcaaggacc ccgagcccgc cttccagcgc agcgccagta ctgctgggga
3121 catcgcctgc gccttccggc ctgtcaagtc tgtcaagatg gctgccccgg tcaaaccacc
3181 agccacacgg cccaagccca ctgtcttccc caaaacaaat gccactagcc ctggtgtcaa
3241 ctcatcaact tccccacagt ctactgacaa gtcttgtact gtctgaggga taataattta
3301 attgttctag acaaggggac tatagggact gactgttatt aaaatcttcc tatttaacta
3361 gcttggggac ttcagttgaa aattaggttc taagttgttc ttgcaggaat tagcctcccc
3421 gtctcccaaa accttgagaa tgaagccctt ggtatcgcct ctcccttccc actgccctct
3481 gcttccccca gtcgtcgtaa ttcagccagc tgcagtccgt accgttctta ggttagccag
3541 agacaggttt tcattatcag gtcactgtga aatctggtaa ggcagtcctg aggacatggg
3601 ctcaagtctc agtcccctca gaccacggtg atgccttgac cagatggttg gctactgcca
3661 tccagctttc agtggcatct tgttttggga actgattata gagaatcata tatagtccag
3721 tcttcatttt acatacacac acatatttta cacacacaca cattttacac acacacacac
3781 acacacacat atgtttttct agtctctggc atgtgtagcc tctcctggtc atagaccagt
3841 ctctttgtaa gttattgtgg cagttcacac agtagccacc aggggtctct gtttccatta
3901 caaactttgt tctgtctggg ccagagaacc tagcctttga aatctctcca tcatatgaaa
3961 cataacggga tgggacaatc ccgtaacctg tttggggttg ggggctttct ctctgtgttc
4021 tttccattga tgtgaattgg tcattggtgt ttgctcttgc ctctcctcca tcccctagaa
4081 gtacaccccc gtcttattaa ggagctttta aagtttttct gaatgtatag acatttctcg
4141 ggttcctacc tttgtctctg atggaccatt ttccatttaa gacattttcc tgtataagac
4201 agttttatag ctggttcctt ttagggtaaa gagtcttaag agagttttat tgtgtctatg
4261 gcaggtttgg gaaaggtaag aaatgggtcc tttttcctcc taatgttttt ggcacttaaa
4321 acataaaatt cattatccta ttaaaaaatt aaattcagct ttgctaatcc agaaatattc
4381 cccaaatgaa aacttgtttt aagtccaccc cttagtttcc ttattttaca aggtctctct
4441 tcagggacca acaggggctt agagagcctt agttagatta aagggagacc ctacctctta
4501 aaaccagttt tcatttatgc aaacaaggac aattaaggga accctgaccc cacaggctct
4561 caagtcttcc caaggccaga atcgaaagaa aattaaaatt tgaatgctga atattctggc
4621 tctactctgg ccttttttct ggttcccttc caaaatgcac aaatcatacc cttgtctgct
4681 ccaattcagt ctccaaacct ggtgcctgtg
//