LOCUS BC132765 2742 bp mRNA linear HUM 06-DEC-2007
DEFINITION Homo sapiens ADAM metallopeptidase domain 23, mRNA (cDNA clone
MGC:164396 IMAGE:40146787), complete cds.
ACCESSION BC132765
VERSION BC132765.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2742)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2742)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 9 Row: E Column: 3.
FEATURES Location/Qualifiers
source 1..2742
/db_xref="H-InvDB:HIT000390818"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:164396 IMAGE:40146787"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: TCGGGTCA"
gene 1..2742
/gene="ADAM23"
/gene_synonym="MDC3"
/db_xref="GeneID:8745"
/db_xref="HGNC:HGNC:202"
/db_xref="MIM:603710"
CDS 204..2702
/gene="ADAM23"
/gene_synonym="MDC3"
/codon_start=1
/product="ADAM metallopeptidase domain 23"
/protein_id="AAI32766.1"
/db_xref="GeneID:8745"
/db_xref="HGNC:HGNC:202"
/db_xref="MIM:603710"
/translation="MKPPGSSSRQPPLAGCSLAGASCGPQRGPAGSVPASAPARTPPC
RLLLVLLLLPPLAASSRPRAWGAAAPSAPHWNETAEKNLGVLADEDNTLQQNSSSNIS
YSNAMQKEITLPSRLIYYINQDSESPYHVLDTKARHQQKHNKAVHLAQASFQIEAFGS
KFILDLILNNGLLSSDYVEIHYENGKPQYSKGGEHCYYHGSIRGVKDSKVALSTCNGL
HGMFEDDTFVYMIEPLELVHDEKSTGRPHIIQKTLAGQYSKQMKNLTMERGDQWPFLS
ELQWLKRRKRAVNPSRGIFEEMKYLELMIVNDHKTYKKHRSSHAHTNNFAKSVVNLVD
SIYKEQLNTRVVLVAVETWTEKDQIDITTNPVQMLHEFSKYRQRIKQHADAVHLISRV
TFHYKRSSLSYFGGVCSRTRGVGVNEYGLPMAVAQVLSQSLAQNLGIQWEPSSRKPKC
DCTESWGGCIMEETGVSHSRKFSKCSILEYRDFLQRGGGACLFNRPTKLFEPTECGNG
YVEAGEECDCGFHVECYGLCCKKCSLSNGAHCSDGPCCNNTSCLFQPRGYECRDAVNE
CDITEYCTGDSGQCPPNLHKQDGYACNQNQGRCYNGECKTRDNQCQYIWGTKAAGSDK
FCYEKLNTEGTEKGNCGKDGDRWIQCSKHDVFCGFLLCTNLTRAPRIGQLQGEIIPTS
FYHQGRVIDCSGAHVVLDDDTDVGYVEDGTPCGPSMMCLDRKCLQIQALNMSSCPLDS
KGKVCSGHGVCSNEATCICDFTWAGTDCSIRDPVRNLHPPKDEGPKGPSATNLIIGSI
AGAILVAAIVLGGTGWGFKNVKKRRFDPTQQGPI"
BASE COUNT 707 a 695 c 733 g 607 t
ORIGIN
1 gagtggctgc gaggctaggc gagccgggaa agggggcgcc gcccagcccc gagccccgcg
61 ccccgtgccc cgagcccgga gccccctgcc cgccgcggca ccatgcgcgc cgagccggcg
121 tgaccggctc cgcccgcggc cgccccgcag ctagcccggc gctctcgccg gccacacgga
181 gcggcgcccg ggagctatga gccatgaagc cgcccggcag cagctcgcgg cagccgcccc
241 tggcgggctg cagccttgcc ggcgcttcct gcggccccca acgcggcccc gccggctcgg
301 tgcctgccag cgccccggcc cgcacgccgc cctgccgcct gcttctcgtc cttctcctgc
361 tgcctccgct cgccgcctcg tcccggcccc gcgcctgggg ggctgctgcg cccagcgctc
421 cgcattggaa tgaaactgca gaaaaaaatt tgggagtcct ggcagatgaa gacaatacat
481 tgcaacagaa tagcagcagt aatatcagtt acagcaatgc aatgcagaaa gaaatcacac
541 tgccttcaag actcatatat tacatcaacc aagactcgga aagcccttat cacgttcttg
601 acacaaaggc aagacaccag caaaaacata ataaggctgt ccatctggcc caggcaagct
661 tccagattga agccttcggc tccaaattca ttcttgacct catactgaac aatggtttgt
721 tgtcttctga ttatgtggag attcactacg aaaatgggaa accacagtac tctaagggtg
781 gagagcactg ttactaccat ggaagcatca gaggcgtcaa agactccaag gtggctctgt
841 caacctgcaa tggacttcat ggcatgtttg aagatgatac cttcgtgtat atgatagagc
901 cactagagct ggttcatgat gagaaaagca caggtcgacc acatataatc cagaaaacct
961 tggcaggaca gtattctaag caaatgaaga atctcactat ggaaagaggt gaccagtggc
1021 cctttctctc tgaattacag tggttgaaaa gaaggaagag agcagtgaat ccatcacgtg
1081 gtatatttga agaaatgaaa tatttggaac ttatgattgt taatgatcac aaaacgtata
1141 agaagcatcg ctcttctcat gcacatacca acaactttgc aaagtccgtg gtcaaccttg
1201 tggattctat ttacaaggag cagctcaaca ccagggttgt cctggtggct gtagagacct
1261 ggactgagaa ggatcagatt gacatcacca ccaaccctgt gcagatgctc catgagttct
1321 caaaataccg gcagcgcatt aagcagcatg ctgatgctgt gcacctcatc tcgcgggtga
1381 catttcacta taagagaagc agtctgagtt actttggagg tgtctgttct cgcacaagag
1441 gagttggtgt gaatgagtat ggtcttccaa tggcagtggc acaagtatta tcgcagagcc
1501 tggctcaaaa ccttggaatc caatgggaac cttctagcag aaagccaaaa tgtgactgca
1561 cagaatcctg gggtggctgc atcatggagg aaacaggggt gtcccattct cgaaaatttt
1621 caaagtgcag cattttggag tatagagact ttttacagag aggaggtgga gcctgccttt
1681 tcaacaggcc aacaaagcta tttgagccca cggaatgtgg aaatggatac gtggaagctg
1741 gggaggagtg tgattgtggt tttcatgtgg aatgctatgg attatgctgt aagaaatgtt
1801 ccctctccaa cggggctcac tgcagcgacg ggccctgctg taacaatacc tcatgtcttt
1861 ttcagccacg agggtatgaa tgccgggatg ctgtgaacga gtgtgatatt actgaatatt
1921 gtactggaga ctctggtcag tgcccaccaa atcttcataa gcaagacgga tatgcatgca
1981 atcaaaatca gggccgctgc tacaatggcg agtgcaagac cagagacaac cagtgtcagt
2041 acatctgggg aacaaaggct gcagggtctg acaagttctg ctatgaaaag ctgaatacag
2101 aaggcactga gaagggaaac tgcgggaagg atggagaccg gtggattcag tgcagcaaac
2161 atgatgtgtt ctgtggattc ttactctgta ccaatcttac tcgagctcca cgtattggtc
2221 aacttcaggg tgagatcatt ccaacttcct tctaccatca aggccgggtg attgactgca
2281 gtggtgccca tgtagtttta gatgatgata cggatgtggg ctatgtagaa gatggaacgc
2341 catgtggccc gtctatgatg tgtttagatc ggaagtgcct acaaattcaa gccctaaata
2401 tgagcagctg tccactcgat tccaagggta aagtctgttc gggccatggg gtgtgtagta
2461 atgaagccac ctgcatttgt gatttcacct gggcagggac agattgcagt atccgggatc
2521 cagttaggaa ccttcacccc cccaaggatg aaggacccaa gggtcctagt gccaccaatc
2581 tcataatagg ctccatcgct ggtgccatcc tggtagcagc tattgtcctt gggggcacag
2641 gctggggatt taaaaatgtc aagaagagaa ggttcgatcc tactcagcaa ggccccatct
2701 gaatcagctg cgctggatgg acaccgcctt gcactgttgg at
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