LOCUS BC132683 4027 bp mRNA linear HUM 06-DEC-2007
DEFINITION Homo sapiens AF4/FMR2 family, member 2, mRNA (cDNA clone MGC:164314
IMAGE:40146705), complete cds.
ACCESSION BC132683
VERSION BC132683.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4027)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4027)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (31-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 9 Row: A Column: 17.
FEATURES Location/Qualifiers
source 1..4027
/db_xref="H-InvDB:HIT000390738"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:164314 IMAGE:40146705"
/tissue_type="Cerebellum, Lung, PCR rescued clones"
/clone_lib="NIH_MGC_347"
/lab_host="DH10B"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: GGCCAACA"
gene 1..4027
/gene="AFF2"
/gene_synonym="FRAXE"
/gene_synonym="MRX2"
/gene_synonym="OX19"
/db_xref="GeneID:2334"
/db_xref="HGNC:HGNC:3776"
/db_xref="MIM:309548"
CDS 52..3957
/gene="AFF2"
/gene_synonym="FRAXE"
/gene_synonym="MRX2"
/gene_synonym="OX19"
/codon_start=1
/product="AFF2 protein"
/protein_id="AAI32684.1"
/db_xref="GeneID:2334"
/db_xref="HGNC:HGNC:3776"
/db_xref="MIM:309548"
/translation="MDLFDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEDDLF
SSGFDLFGEPYKTNKGDALANRVQNTLGNYDEMKNLLTNHSNQNHLVGIPKNSVPQNP
NNKNEPSFFPEQKNRIIPPHQDNTHPSAPMPPPSVVILNSTLIHSNRKSKPEWSRDSH
NPSTVLASQASGQPNKMQTLTQDQSQAKLEDFFVYPAEQPQIGEVEESNPSAKEDSNP
NSSGEDAFKEIFQSNSPEESEFAVQAPGSPLVASSLLAPSSGLSVQNFPPGLYCKTSM
GQQKPTAYVRPMDGQDQAPDISPTLKPSIEFENSFGNLSFGTLLDGKPSAASSKTKLP
KFTILQTSEVSLPSDPSCVEEILREMTHSWPTPLTSMHTAGHSEQSTFSIPGQESQHL
TPGFTLQKWNDPTTRASTKMLEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKP
RNNPVNPPLATPQPPPAVQASGGSGSSSESESSSESDSDTESSTTDSESNEAPRVATP
EPEPPSTNKWQLDKWLNKVTSQNKSFICGQNETPMETISLPPPIIQPMEVQMKVKTNA
SQVPAEPKERPLLSLIREKARPRPTQKIPETKALKHKLSTTSETVSQRTIGKKQPKKV
EKNTSTDEFTWPKPNITSSTPKEKESVELHDPPRGRNKATAHKPAPRKEPRPNIPLAP
EKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEETLQIKVLPPCIISGGNTAKSKEIC
GASLTLSTLMSSSGSNNNLSISNEEPTFSPIPVMQTEILSPLRDHENLKNLWVKIDLD
LLSRVPGHSSLHAAPAKPDHKETATKPKRQTAVTAVEKPAPKGKRKHKPIEVAEKIPE
KKQRLEEATTICLLPPCISPAPPHKPPNTRENNSSRRANRRKEEKLFPPPLSPLPEDP
PRRRNVSGNNGPFGQDKNIAMTGQITSTKPKRTEGKFCATFKGISVNEGDTPKKASSA
TITVTNTAIATATVTATAIVTTTVTATATATATTTTTTTTISTITSTITTGLMDSSHL
EMMSWAALPLLSSSSTNVRRPKLTFDDSVHNADYYMQEAKKLKHKADALFEKFGKAVN
YADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRLKNFASPLASDGDKKLA
VLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIPSPWVSNGKNTPSPV
SLNNVSPINAMGNCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRENKE
FFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL"
BASE COUNT 1227 a 1126 c 843 g 831 t
ORIGIN
1 acccgctgcg atcagggaca ggcgcccgcc cgccgccgcc gcctggccgc tatggatcta
61 ttcgactttt tcagagactg ggacttggag cagcagtgtc actatgaaca agaccgtagt
121 gcacttaaaa aaagggaatg ggagcggagg aatcaagaag tccagcaaga agacgatctc
181 ttttcttcag gctttgatct ttttggggag ccatacaaga caaacaaagg tgatgcactt
241 gccaaccgag tccagaacac gcttggaaac tatgatgaaa tgaagaattt gctaactaac
301 cattctaatc agaatcacct agtgggaatt ccaaagaatt ctgtgcccca gaatcccaac
361 aacaaaaatg aaccaagctt ttttccagaa caaaagaaca gaataattcc acctcaccag
421 gataataccc atccttcagc accaatgcct ccaccttctg ttgtgatact gaattcaact
481 ctaatacaca gcaacagaaa atcaaaacct gagtggtcac gtgatagtca taaccctagc
541 actgtactgg caagccaggc cagtggtcag ccaaacaaga tgcagacttt gacacaggac
601 cagtctcaag ccaaactgga agacttcttt gtctacccag ctgaacagcc ccagattgga
661 gaagttgaag agtcaaaccc atctgcaaag gaagacagta accctaattc tagtggagaa
721 gatgctttca aagaaatctt tcaatccaat tcaccggaag aatctgaatt cgccgtgcaa
781 gcgcctgggt ctcccctagt ggcttcctct ttattagctc ctagcagtgg cctttcagtt
841 caaaacttcc caccagggct ttactgcaaa acaagcatgg ggcagcaaaa gccaactgca
901 tacgtcagac ccatggatgg ccaggaccag gcaccggaca tctcaccaac actgaaacct
961 tcaattgaat ttgagaacag ctttgggaat ctgtcatttg gaacactctt ggatggaaaa
1021 cccagtgcag ccagttcaaa gactaaactg ccaaagttca ccatcctcca aacaagtgaa
1081 gtaagccttc ccagtgatcc aagctgtgtt gaagaaatct tgcgggagat gacccattcc
1141 tggcctactc ctctcacttc catgcatact gctggacact ctgagcagag caccttttcc
1201 atcccaggac aggaatcgca gcatctgacc ccaggattca ccttacaaaa gtggaatgac
1261 ccaaccacca gagcttctac aaagatgctt gaggatgacc tgaagctgag cagtgatgaa
1321 gatgaccttg agcctgtgaa gaccttgacc actcagtgca ctgccactga gctctaccag
1381 gctgttgaaa aggcaaaacc taggaataat cctgtgaacc cacccttggc cactccccag
1441 cccccacctg cagtgcaagc cagcgggggt tctggcagct ccagcgaatc ggagagcagc
1501 tctgagtcgg attcagacac tgaaagtagc accactgaca gcgaatctaa tgaggcacct
1561 cgtgtggcaa ctccagagcc tgagccaccc tcaaccaaca agtggcaact ggataaatgg
1621 cttaacaaag tgacatccca gaacaagtct tttatttgtg gccaaaatga aacacccatg
1681 gagactattt ctctgcctcc tccaatcatc caaccaatgg aagtccagat gaaagtgaag
1741 acgaatgcca gtcaggtccc agctgaaccc aaagaaaggc ctctcctcag tctcattagg
1801 gagaaagccc gtccacggcc cactcagaaa attccagaaa caaaggcttt gaagcataag
1861 ttgtcaacaa ctagtgagac agtgtctcaa aggacaattg ggaaaaaaca gcccaaaaaa
1921 gttgagaaga acaccagcac tgacgagttt acctggccca aaccaaatat taccagcagc
1981 actcccaaag aaaaagaaag tgtggagctt catgacccac caagaggccg caacaaagcc
2041 actgcccaca aaccagcccc taggaaagaa ccaagaccta acatcccttt ggctcccgag
2101 aagaagaagt acagagggcc tggcaagatt gtgccaaagt ctcgggaatt cattgaaaca
2161 gattcatcta catctgactc caacacagat caggaagaga ccctgcaaat caaagtcctg
2221 cctccgtgca ttatttctgg aggtaatact gccaaatcca aggaaatctg tggtgccagc
2281 ctgaccctca gcaccttaat gagtagcagt ggcagcaaca acaacttatc catcagtaat
2341 gaagagccaa cattttcacc tattcctgtc atgcaaactg aaatcctgtc ccctctgcga
2401 gatcatgaga acctgaaaaa cctctgggtg aagattgacc ttgacttact ctctagagta
2461 cctggccaca gctcactcca tgcagcacct gccaagccag accacaagga gactgccaca
2521 aaacccaagc gtcagacagc tgtcacagct gtggagaaac cagcccctaa gggcaaacgt
2581 aagcacaagc caatagaagt tgcagagaag atccctgaga agaagcagcg cctggaggag
2641 gccacaacta tctgcttgct ccctccttgc atctcaccag ccccacccca caagcctccc
2701 aacactagag aaaataattc atccaggaga gcaaatagaa gaaaggaaga aaaactattt
2761 cctcctccac tttccccact gccagaggac cctccacgcc gcagaaatgt cagtggcaat
2821 aatggtccct ttggtcaaga caaaaacatc gccatgactg gacaaatcac atctaccaaa
2881 cctaagagaa ctgaaggcaa attctgtgct actttcaaag ggatatcggt aaatgaggga
2941 gacactccaa aaaaggcatc ctctgccacc atcactgtca ccaatactgc tattgccact
3001 gctactgtca ctgctactgc cattgtcacc accactgtca cagctactgc caccgccacg
3061 gccaccacca caactactac cactaccatt tccaccatca cctctaccat cactactggc
3121 ctcatggata gcagtcacct ggagatgatg tcctgggcgg ctctgcccct tctatccagc
3181 agcagcacta atgtccggag acccaagctc acttttgatg actcggttca caatgctgat
3241 tattacatgc aagaagctaa gaagctgaag cacaaagctg atgcactgtt cgagaaattt
3301 ggcaaagctg tgaattatgc tgatgccgcc ctctccttca ctgaatgtgg caatgccatg
3361 gaacgcgacc ctctggaagc aaagtcccca tacaccatgt actctgagac tgtggagctc
3421 ctcaggtatg caatgaggct gaagaacttt gcaagtccct tggcttcgga tggggacaaa
3481 aagctagcag tactatgcta ccgatgttta tcactcctct atttgagaat gtttaagctg
3541 aagaaggacc atgctatgaa gtactccaga tcactgatgg aatattttaa gcaaaatgct
3601 tcaaaagtcg cacagatacc ctctccatgg gtaagcaatg gaaagaacac tccatcccca
3661 gtgtctctca acaacgtctc ccccatcaac gcaatgggga actgtaacaa tggcccagtc
3721 accattcccc agcgcattca ccacatggct gccagccacg tcaacatcac tagcaatgtg
3781 ttacggggct atgaacactg ggatatggcc gacaaactga caagagaaaa caaagaattc
3841 tttggtgatc tggacacgct gatggggcct ctgacccagc acagcagcat gaccaatctt
3901 gtccgctacg ttcgccaagg actgtgttgg ctgcgcatcg atgcccactt gttgtagtgg
3961 gtgttctcag atctctagca tcacgaccca tcactctacc tctaccagcg cactgatggt
4021 cactggt
//