LOCUS BC131820 6732 bp mRNA linear HUM 30-JAN-2007
DEFINITION Homo sapiens Fraser syndrome 1, mRNA (cDNA clone IMAGE:40126796),
complete cds.
ACCESSION BC131820
VERSION BC131820.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 6732)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 6732)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 30 Row: p Column: 23
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..6732
/db_xref="H-InvDB:HIT000390712"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40126796"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: TGCATCAC sequenced from the reverse primer"
gene 1..6732
/gene="FRAS1"
/db_xref="GeneID:80144"
/db_xref="HGNC:HGNC:19185"
/db_xref="MIM:607830"
CDS 31..5961
/gene="FRAS1"
/codon_start=1
/product="FRAS1 protein"
/protein_id="AAI31821.1"
/db_xref="GeneID:80144"
/db_xref="HGNC:HGNC:19185"
/db_xref="MIM:607830"
/translation="MGVLKVWLGLALALAEFAVLPHHSEGACVYQDSLLADATIWKPD
SCQSCRCHGDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIH
EHGTEWASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCS
YEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQCSA
RSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQACLPLRCGKGQSRARRHGQCCE
ECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQTGECAKVECARDEELIHL
DGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQVTCY
EPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWC
VHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTCGDGFYQDRH
SCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNRQGTCSACDQSCD
SCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADATGRCKVCHNSCASCSGPTPSHCT
ACSPPKALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQV
EQLSDVGIPSGECLAQCRAHFYLESTGICEACHQSCFRCAGKSPHNCTDCGPSHVLLD
GQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQ
FLNLVGYCADCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYYAERGA
CKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHVCQPCNTHCG
SCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKTD
CLQCMDGYVLQDGACVEQCLSSFYQDSGLCKNCDSYCLQCQGPHECTRCKGPFLLLEA
QCVQECGKGYFADHAKHKCTACPQGCLQCSHRDRCHLCDHGFFLKSGLCVYNCVPGFS
VHTSNETCSGKIHTPSLHVNGSLILPIGSIKPLDFSLLNVQDQEGRVEDLLFHVVSTP
TNGQLVLSRNGKEVQLDKAGRFSWKDVNEKKVRFVHSKEKLRKGYLFLKISDQQFFSE
PQLINIQAFSTQAPYVLRNEVLHISRGERATITTQMLDIRDDDNPQDVVIEIIDPPLH
GQLLQTLQSPATPIYQFQLDELSRGLLHYAHDGSDSTSDVAVLQANDGHSFHNILFQV
KTVPQNDRGLQLVANSMVWVPEGGMLQITNRILQAEAPGASAEEIIYKITQDYPQFGE
VVLLVNMPADSPADEGQHLPDGRTATPTSTFTQQDINEGIVWYRHSGAPAQSDSFRFE
VSSASNAQTRLESHMFNIAILPQTPEAPKVSLEASLHMTAREDGLTVIQPHSLSFINS
EKPSGKIVYNITLPLHPNQGIIEHRDHPHSPIRYFTQEDINQGKVMYRPPPAAPHLQE
LMAFSFAGLPESVKFHFTVSDGEHTSPEMVLTIHLLPSDQQLPVFQVTAPRLAVSPGG
STSVGLQVVVRDAETAPKELFFELRRPPQHGVLLKHTAEFRRPMATGDTFTYEDVEKN
ALQYIHDGSSTREDSMEISVTDGLTVTMLEVRVEVSLSEDRGPRLAAGSSLSITVASK
STAIITRSHLAYVDDSSPDPEIWIQLNYLPSYGTLLRISGSEVEELSEVSNFTMEDIN
NKKIRYSAVFETDGHLVTDSFYFSVSDMDHNHLDNQIFTIMITPAENPPPVIAFADLI
TVDEGGRAPLSFHHFFATDDDDNLQRDAIIKLSALPKYGCIENTGTGDRFGPETASDL
EASFPIQDVLENYIYYFQSVHESIEPTHDIFSFYVSDGTSRSEIHSINITIEVKTLEV
GKVEPLTTIFHTIRELSL"
BASE COUNT 1647 a 1684 c 1689 g 1712 t
ORIGIN
1 ggctcctcca tcgtgggtgc cgaggcggcg atgggtgtcc tcaaagtgtg gctcgggctg
61 gccctagcgt tggcggaatt tgcagtattg cctcatcatt ccgaaggtgc ttgtgtctat
121 caggattcct tgttggcgga tgccacaatt tggaagcccg attcatgcca gagctgccgt
181 tgccatggtg atattgttat ctgcaaacct gctgtttgca gaaaccctca atgtgccttt
241 gagaagggag aagtgcttca aatagctgcc aaccaatgct gtcctgagtg tgttttgagg
301 actccaggat cttgccatca tgaaaagaaa atccatgagc atgggacaga atgggcctct
361 tctccatgta gtgtgtgctc ttgcaatcat ggggaagtcc gatgtacccc ccaaccatgc
421 ccaccgctgt catgtggaca ccaggagctg gcattcatcc ctgaaggaag ctgctgccca
481 gtttgtgtgg gccttgggaa accctgttcc tatgaaggcc atgtgtttca ggatggggag
541 gactggcggc tgagccggtg tgccaaatgt ctgtgtagaa atggggttgc ccagtgcttc
601 acagctcagt gtcagcctct attttgtaac caggatgaga ctgtagtccg agtccctgga
661 aaatgttgcc cgcagtgctc tgcaagatcc tgctctgcag ctggccaagt atacgagcat
721 ggtgagcagt ggagcgaaaa tgcctgcacc acgtgtatat gtgaccgggg tgaggtcagg
781 tgtcacaagc aggcctgcct gcccctgaga tgcggaaagg gtcagagcag ggctcggcgt
841 catgggcaat gctgtgagga atgtgtgtct cctgccggga gctgctccta tgatggagtt
901 gtgcggtacc aggacgaaat gtggaagggc tcggcctgtg agttctgcat gtgtgatcat
961 ggccaagtga cctgccagac tggagagtgt gccaaagtgg agtgtgcccg ggatgaagaa
1021 ttaattcact tagatggaaa gtgttgtcct gaatgcattt caaggaatgg ttattgtgtt
1081 tatgaagaaa ctggagaatt tatgtcatca aatgctagtg aagttaaacg tattccagag
1141 ggagagaagt gggaagatgg cccttgcaag gtgtgtgagt gccgaggggc tcaggtaact
1201 tgctacgagc cctcttgccc accatgtcca gtgggcacac tggccttaga ggtgaaggga
1261 cagtgctgtc cagactgcac atcagttcat tgccatccag attgtttgac atgctctcag
1321 tctccagacc actgtgacct ctgccaagat cctaccaagt tactgcagaa tggatggtgt
1381 gtgcacagct gtggactggg tttttaccaa gctggcagtc tctgtttagc ctgccagccc
1441 cagtgctcca cgtgtaccag tgggctggag tgctcatcct gccagcctcc cctgctgatg
1501 cggcacgggc agtgtgtgcc tacctgtggg gacggcttct accaagatcg ccattcctgt
1561 gcagtctgcc atgagtcctg tgcaggttgc tggggcccaa cggagaagca ctgcttggcc
1621 tgcagagatc ccctccacgt gctgagagat ggcggctgtg agagcagctg tggaaaaggc
1681 ttctacaaca ggcagggcac ctgtagcgct tgtgaccaat cctgtgacag ttgtggcccc
1741 agtagcccca ggtgtcttac ctgtactgag aagacagtgc tgcatgatgg gaaatgcatg
1801 tctgaatgcc ctggcgggta ctatgctgat gccactggca ggtgcaaagt ttgtcataac
1861 tcatgtgcca gctgctctgg gcccacaccc tctcactgta cagcctgcag cccccccaag
1921 gctctgcgtc aaggccactg tctgccccgc tgtggagagg gtttctactc tgaccatgga
1981 gtctgcaaag cctgtcactc ctcctgcctg gcttgtatgg gtcccgcacc ctctcactgt
2041 actgggtgta agaagccaga ggaaggactg caagtggagc agctgtctga cgtgggcatc
2101 ccctctggcg agtgtctagc ccagtgtaga gcccattttt acttggagag cactggcata
2161 tgtgaagctt gccaccagtc ctgtttcaga tgtgcaggga aaagcccaca taactgcaca
2221 gactgtgggc cttcccatgt gctgttggat gggcagtgcc tctcccagtg cccagatggc
2281 tactttcacc aggaaggtag ttgcacagag tgtcacccaa cctgcaggca gtgtcatggg
2341 ccgttggagt ctgactgcat ctcctgttac cctcacatct ctcttaccaa tggtaactgc
2401 aggaccagct gcagggaaga gcagttcctc aacctcgtgg gatactgtgc tgactgccat
2461 cacctgtgcc agcactgtgc agctgatctc cacaacactg ggagcatctg cctcaggtgc
2521 cagaatgccc actacctgct gctcggggac cactgtgttc ctgactgccc ttcaggatac
2581 tatgcagaga gaggagcttg taaaaaatgc cactcctcct gcagaacctg ccagggcaga
2641 ggacctttct cctgctcctc atgtgacacc aacctcgtgc tgtcccacac tggcacctgc
2701 agcaccacct gcttccctgg gcactatctt gatgacaatc atgtttgcca gccatgcaac
2761 acacactgtg gaagctgtga ttcacaggcc agctgtacct cctgccgaga tccaaacaag
2821 gttctgctct ttggggaatg tcaatacgag agctgcgccc cacagtacta tcttgacttc
2881 tccaccaaca cgtgcaaaga gtgtgattgg agctgcagtg catgcagtgg gcccctgaaa
2941 acagactgcc tgcagtgcat ggatggctat gttctccagg atggggcctg cgtggagcag
3001 tgcttgtcat cattttacca ggactcgggc ctctgtaaga actgtgacag ctactgtctc
3061 cagtgccaag gtccccatga gtgtacccgc tgcaaagggc catttctcct cttggaagcc
3121 cagtgtgtcc aggaatgtgg gaaggggtac tttgcagatc atgcaaagca caaatgcaca
3181 gcctgccctc aggggtgctt gcagtgcagc cacagggacc gttgtcacct ctgtgaccat
3241 gggttctttc tgaagagtgg cctctgtgtt tacaactgtg ttcctggctt ttctgtccac
3301 acctctaatg aaacatgttc tggcaaaata cacaccccta gtcttcatgt gaatggttcc
3361 ctgatcctcc caattggttc aataaagcca ctggattttt ccctcctgaa tgtccaagac
3421 caggagggta gggtcgaaga tctcctattt catgttgtga gcactcccac caatggtcag
3481 ctagtgctct caagaaatgg aaaagaggtt cagctggaca aggctggccg ttttagctgg
3541 aaagatgtga acgagaagaa agtgcgtttt gtgcacagca aagaaaaact caggaaaggt
3601 taccttttcc tgaaaattag tgaccagcag ttcttctctg agccacagct gatcaacata
3661 caagcatttt caacacaggc cccctatgtg ctgagaaatg aagttctcca cattagcaga
3721 ggagagaggg caaccatcac cacccagatg cttgacatcc gagatgatga caacccacag
3781 gatgtggtca ttgaaataat cgatcctcca cttcatggcc aattgcttca gacacttcag
3841 tccccggcaa cccctatcta tcaattccag ctggatgaac tctctagagg ccttctccac
3901 tatgctcatg atggttcaga cagcacatcc gatgttgcag tcttgcaggc caatgatgga
3961 cactccttcc ataatatact gttccaagtg aagaccgtgc ctcagaatga caggggtctt
4021 cagcttgtgg ctaattcgat ggtgtgggtt ccagaagggg ggatgctgca gatcaccaac
4081 agaatcttac aggccgaggc tcctggtgcc agtgctgaag aaattatcta caagattaca
4141 caagactacc cccagtttgg ggaggtggtc cttctagtga atatgcctgc agacagccct
4201 gcagatgaag ggcagcacct gcctgatggg aggacagcta cccccaccag caccttcacc
4261 cagcaggaca tcaatgaagg catcgtatgg tacaggcact caggagcccc agcccagagc
4321 gactccttcc gcttcgaggt gtccagtgcc tccaatgccc agacccgcct ggagagccac
4381 atgttcaaca tcgcgatctt accacagaca cctgaagcac ctaaagtgtc tctggaagca
4441 tctctccata tgactgctag agaagatggc ctgactgtta ttcagcctca ttccctctcc
4501 ttcataaact ctgagaagcc aagtggaaag attgtctaca acatcactct acctctgcat
4561 ccaaatcaag gtatcatcga gcaccgggac caccctcact ctcctatccg gtatttcacg
4621 caagaggata ttaaccaggg caaagtcatg taccgccctc ccccggcagc accccacctc
4681 caggagctca tggccttctc gttcgctggt ctcccagaat cagtgaaatt ccacttcaca
4741 gtttcagatg gagaacacac aagtccggag atggtcctca ccattcactt acttcccagt
4801 gatcagcaac tgccagtgtt ccaggtcaca gctccacggc tggcggtcag cccaggaggc
4861 agcacttctg taggacttca ggtggtagta agagatgctg agacagcgcc caaagaactc
4921 ttctttgagc ttcggagacc tccacagcat ggtgtgcttc ttaagcatac agctgagttc
4981 cgaaggccga tggccacagg tgacactttc acctatgagg atgttgagaa aaatgctcta
5041 cagtatatac atgatggttc ctctacccgg gaagacagca tggagatctc agtcacagat
5101 ggcctcacag tgacaatgct ggaggtgaga gtagaggtgt ccctgtcaga agaccgaggg
5161 cctcgactgg ctgctggctc ctctctgagc attactgttg ccagtaaaag cacagccata
5221 atcactaggt cacaccttgc ttacgtggat gattcttccc ccgacccaga gatctggatt
5281 cagttaaatt atctgccctc atatggtact ctcttaagaa tctcaggatc tgaggtggaa
5341 gagctctcag aagtttccaa tttcacaatg gaagacatca ataacaagaa aatcagatac
5401 tcagctgtgt ttgaaactga tggtcatctg gttactgata gcttctattt ctctgtctct
5461 gacatggacc acaaccatct ggataatcag atatttacca tcatgatcac tcctgctgaa
5521 aatccacctc cagtcattgc ttttgctgac cttatcacgg ttgatgaggg agggagagca
5581 ccactctcat ttcaccattt ttttgctact gatgatgatg acaacctcca gagagatgcc
5641 atcattaaac taagtgctct gcccaaatat ggctgcattg agaacacagg aacaggtgat
5701 cgttttggcc ctgaaactgc cagtgaccta gaggcatcat ttcctattca agacgtcctg
5761 gaaaactaca tttactactt tcagagtgtt catgaaagca ttgagccaac ccatgatatt
5821 tttagttttt atgtgagtga tggaaccagt cgttcagaaa ttcacagcat caatatcacc
5881 attgaggtaa agactttgga agttggaaag gttgagccct tgaccacaat atttcacacc
5941 attagagagc tttctttata gggactcaaa agcaaagaag attggatttg accttcaaaa
6001 ttgaaggtcg ttcttaaaat atagccttca ggaatcttgt agaattaagg ttggcatttg
6061 gggaaggctt gagttagaaa tctaaatttc catttcagga ttgaatttat ttgttcggtg
6121 tgaaaaacag tttgtgaagg tcagagatgc tttgccagtc tcatatataa atgaaaactt
6181 acatatgtct atgtttctct gaaattgtgt ttggttctat atgcatattt gccttttctt
6241 attttactgc atttatttat ttaattgtaa catcaaagaa atgtgttcct tgatgctgta
6301 tttattctca tttgagcaac tacacaggct tgctctaccg agagagagac acaggggagg
6361 ggaaagataa atctcagaat gaaataccct ctgccttggg aaaataaaat gtaaagaacc
6421 ctctgcactc ttaagggtca gtggtggaaa ggggctggca ccagggcagg gagacagctt
6481 tagagaccca cactttcaaa tatagtgtcc ttctacaggt actgtggtat gcttagcatt
6541 ttctaagaga gttctgagtt atattagtat ggtcttttat cttcaaagta tgttaatact
6601 tgtacttgtc aaagcacata tccatatttt tggtctagaa aatatggtca ttgtacttac
6661 ggaagatatc tgagaaaact tttatgaaat gtccatcagc ttcttttgaa gggggcattt
6721 tgttgcctgg ac
//