LOCUS BC131779 1523 bp mRNA linear HUM 30-JAN-2007
DEFINITION Homo sapiens leptin receptor, mRNA (cDNA clone IMAGE:40124032),
complete cds.
ACCESSION BC131779
VERSION BC131779.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1523)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1523)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 31 Row: o Column: 18
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1523
/db_xref="H-InvDB:HIT000390680"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40124032"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: CTTTTATT sequenced from
the forward primer"
gene 1..1523
/gene="LEPR"
/gene_synonym="CD295"
/gene_synonym="OBR"
/db_xref="GeneID:3953"
/db_xref="HGNC:HGNC:6554"
/db_xref="MIM:601007"
CDS 738..1436
/gene="LEPR"
/gene_synonym="CD295"
/gene_synonym="OBR"
/codon_start=1
/product="LEPR protein"
/protein_id="AAI31780.1"
/db_xref="GeneID:3953"
/db_xref="HGNC:HGNC:6554"
/db_xref="MIM:601007"
/translation="MMPTTVVSLLSTTDLEKGSVCISDQFNSVNFSEAEGTEVTYEDE
SQRQPFVKYATLISNSKPSETGEEQGLINSSVTKCFSSKNSPLKDSFSNSSWEIEAQA
FFILSDQHPNIISPHLTFSEGLDELLKLEGNFPEENNDKKSIYYLGVTSIKKRESGVL
LTDKSRVSCPFPAPCLFTDIRVLQDSCSHFVENNINLGTSSKKTFASYMPQFQTCSTQ
THKIMENKMCDLTV"
BASE COUNT 471 a 277 c 302 g 473 t
ORIGIN
1 gagacatggc gggcgttaaa gctctcgtgg cattatcctt cagtggggct attggactga
61 cttttcttat gctgggatgt gccttagagg attatgggtg tacttctctg aagtaagatg
121 atttgtcaaa aattctgtgt ggttttgtta cattgggaat ttatttatgt gataactgcg
181 tttaacttgt catatccaat tactccttgg agatttaagt tgtcttgcat gccaccaaat
241 tcaacctatg actacttcct tttgcctgct ggactctcaa agaatacttc aaattcgaat
301 ggacattatg agacagctgt tgaacctaag tttaattcaa gtggtactca cttttctaac
361 ttatccaaaa caactttcca ctgttgcttt cggagtgagc aagatagaaa ctgctcctta
421 tgtgcagaca acattgaagg aaagacattt gtttcaacag taaattcttt agtttttcaa
481 caaatagatg caaactggaa catacagtgc tggctaaaag gagacttaaa attattcatc
541 tgttatgtgg agtcattatt taagaatcta ttcaggaatt ataactataa ggtccatctt
601 ttatatgttc tccagaaacg tttgagcatc tttttgtcaa gcatacagca tcagtgacat
661 gtggtcctct tcttttggag cctgaaacaa tttcagaaga tatcagtgtt gatacatcat
721 ggaaaaataa agatgagatg atgccaacaa ctgtggtctc tctactttca acaacagatc
781 ttgaaaaggg ttctgtttgt attagtgacc agttcaacag tgttaacttc tctgaggctg
841 agggtactga ggtaacctat gaggacgaaa gccagagaca accctttgtt aaatacgcca
901 cgctgatcag caactctaaa ccaagtgaaa ctggtgaaga acaagggctt ataaatagtt
961 cagtcaccaa gtgcttctct agcaaaaatt ctccattgaa ggattctttc tctaatagct
1021 catgggagat agaggcccag gcatttttta tattatcaga tcagcatccc aacataattt
1081 caccacacct cacattctca gaaggattgg atgaactttt gaaattggag ggaaatttcc
1141 ctgaagaaaa taatgataaa aagtctatct attatttagg ggtcacctca atcaaaaaga
1201 gagagagtgg tgtgcttttg actgacaagt caagggtatc gtgcccattc ccagccccct
1261 gtttattcac ggacatcaga gttctccagg acagttgctc acactttgta gaaaataata
1321 tcaacttagg aacttctagt aagaagactt ttgcatctta catgcctcaa ttccaaactt
1381 gttctactca gactcataag atcatggaaa acaagatgtg tgacctaact gtgtaatttc
1441 actgaagaaa ccttcagatt tgtgttataa tgggtaatat aaagtgtaat agattatagt
1501 tgtgggtggg agagagaaaa gaa
//