LOCUS BC131536 5259 bp mRNA linear HUM 30-JAN-2007
DEFINITION Homo sapiens IQ motif containing GTPase activating protein 3, mRNA
(cDNA clone MGC:141847 IMAGE:40082932), complete cds.
ACCESSION BC131536
VERSION BC131536.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5259)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5259)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (29-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 31 Row: d Column: 1.
FEATURES Location/Qualifiers
source 1..5259
/db_xref="H-InvDB:HIT000390499"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:141847 IMAGE:40082932"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: TTTAATCC sequenced from the reverse primer"
gene 1..5259
/gene="IQGAP3"
/db_xref="GeneID:128239"
/db_xref="HGNC:HGNC:20669"
CDS 34..4929
/gene="IQGAP3"
/codon_start=1
/product="IQ motif containing GTPase activating protein 3"
/protein_id="AAI31537.1"
/db_xref="GeneID:128239"
/db_xref="HGNC:HGNC:20669"
/translation="MERRAAGPGWAAYERLTAEEMDEQRRQNVAYQYLCRLEEAKRWM
EACLKEELPSPVELEESLRNGVLLAKLGHCFAPSVVPLKKIYDVEQLRYQATGLHFRH
TDNINFWLSAIAHIGLPSTFFPETTDIYDKKNMPRVVYCIHALSLFLFRLGLAPQIHD
LYGKVKFTAEELSNMASELAKYGLQLPAFSKIGGILANELSVDEAAVHAAVLAINEAV
ERGVVEDTLAALQNPSALLENLREPLAAVYQEMLAQAKMEKAANARNHDDRESQDIYD
HYLTQAEIQGNINHVNAHGALEVVDDALERQSPEALLKALQDPALALRGVRRDFADWY
LEQLNSDREQKAQELGLVELLEKEEVQAGVAAANTKGDQEQAMLHAVQRINKAIRRGV
AADTVKELMCPEAQLPPVYPVASSMYQLELAVLQQQQGELGQEELFVAVEMLSAVVLI
NRALEARDASGFWSSLVNPATGLAEVEGENAQRYFDALLKLRQERGMGEDFLSWNDLQ
ATVSQVNAQTQEETDRVLAVSLINEALDKGSPEKTLSALLLPAAGLDDVSLPVAPRYH
LLLVAAKRQKAQVTGDPGAVLWLEEIRQGVVRANQDTNTAQRMALGVAAINQAIKEGK
AAQTERVLRNPAVALRGVVPDCANGYQRALESAMAKKQCPADTAFWVQHDMKDGTAYY
FHLQTFQGIWEQPPGCPLNTSHLTREEIQSAVTKVTAAYDRQQLWKANVGFVIQLQAR
LRGFLVRQKFAEHSHFLRTWLPAVIKIQAHWRGYRQRKIYLEWLQYFKANLDAIIKIQ
AWARMWAARRQYLRRLHYFQKNVNSIVKIQAFFRARKAQDDYRILVHAPHPPLSVVRR
FAHLLNQSQQDFLAEAELLKLQEEVVRKIRSNQQLEQDLNIMDIKIGLLVKNRITLQE
VVSHCKKLTKRNKEQLSDMMVLDKQKGLKSLSKEKRQKLEAYQHLFYLLQTQPIYLAK
LIFQMPQNKTTKFMEAVIFSLYNYASSRREAYLLLQLFKTALQEEIKSKVEQPQDVVT
GNPTVVRLVVRFYRNGRGQSALQEILGKVIQDVLEDKVLSVHTDPVHLYKNWINQTEA
QTGQRSHLPYDVTPEQALSHPEVQRRLDIALRNLLAMTDKFLLAITSSVDQIPYGMRY
VAKVLKATLAEKFPDATDSEVYKVVGNLLYYRFLNPAVVAPDAFDIVAMAAGGALAAP
QRHALGAVAQLLQHAAAGKAFSGQSQHLRVLNDYLEETHLKFRKFIHRACQVPEPEER
FAVDEYSDMVAVAKPMVYITVGELVNTHRLLLEHQDCIAPDHQDPLHELLEDLGELPT
IPDLIGESIAADGHTDLSKLEVSLTLTNKFEGLEADADDSNTRSLLLSTKQLLADIIQ
FHPGDTLKEILSLSASREQEAAHKQLMSRRQACTAQTPEPLRRHRSLTAHSLLPLAEK
QRRVLRNLRRLEALGLVSARNGYQGLVDELAKDIRNQHRHRHRRKAELVKLQATLQGL
STKTTFYEEQGDYYSQYIRACLDHLAPDSKSSGKGKKQPSLHYTAAQLLEKGVLVEIE
DLPASHFRNVIFDITPGDEAGKFEVNAKFLGVDMERFQLHYQDLLQLQYEGVAVMKLF
NKAKVNVNLLIFLLNKKFLRK"
BASE COUNT 1257 a 1481 c 1489 g 1032 t
ORIGIN
1 ggcgggagat tcaaacctgg aagaaggagg aacatggaga ggagagcagc gggcccaggc
61 tgggcagcct atgaacgcct cacagctgag gagatggatg agcagaggcg gcagaatgtt
121 gcctatcagt acctgtgccg gctggaggag gccaagcgct ggatggaggc ctgcctgaag
181 gaggagcttc cttccccggt ggagctggag gagagccttc ggaatggagt gctgctggcc
241 aagctgggcc actgttttgc accctccgtg gttccgttga agaagatcta cgatgtggag
301 cagctgcggt accaggcaac tggcttacat ttccgtcaca cagacaacat caacttttgg
361 ctatctgcaa tagcccacat cggtctgcct tcgaccttct tcccagagac cacggacatc
421 tatgacaaaa agaacatgcc ccgggtagtc tactgcatcc atgctctcag tctcttcctc
481 ttccggctgg gattggcccc tcagatacat gatctatacg ggaaagtgaa attcacagct
541 gaggaactca gcaacatggc gtccgaactg gccaaatatg gcctccagct gcctgccttc
601 agcaagatcg ggggcatctt ggccaatgag ctctcggtgg atgaggctgc agtccatgca
661 gctgttcttg ccatcaatga agcagtggag cgaggggtgg tggaggacac cctggctgcc
721 ttgcagaatc ccagtgctct tctggagaat ctccgagagc ctctggcagc cgtctaccag
781 gagatgctgg cccaggccaa gatggagaag gcagccaatg ccaggaacca tgatgacaga
841 gaaagccagg acatctatga ccactaccta actcaggctg aaatccaggg caatatcaac
901 catgtcaacg cccatggggc tctagaagtt gttgatgatg ccctggaaag acagagccct
961 gaagccttgc tcaaggccct tcaagaccct gccctggccc tgcgaggggt gaggagagac
1021 tttgctgact ggtacctgga gcagctgaac tcagacagag agcagaaggc acaggagctg
1081 ggcctggtgg agcttctgga aaaggaggaa gtccaggctg gtgtggctgc agccaacaca
1141 aagggtgatc aggaacaagc catgctccac gctgtgcagc ggatcaacaa agccatccgg
1201 aggggagtgg cggctgacac tgtgaaggag ctgatgtgcc ctgaggccca gctgcctcca
1261 gtgtaccctg ttgcatcgtc tatgtaccag ctggagctgg cagtgctcca gcagcagcag
1321 ggggagcttg gccaggagga gctcttcgtg gctgtggaga tgctctcagc tgtggtcctg
1381 attaaccggg ccctggaggc ccgggatgcc agtggcttct ggagcagcct ggtgaaccct
1441 gccacaggcc tggctgaggt ggaaggagaa aatgcccagc gttacttcga tgccctgctg
1501 aaattgcgac aggagcgtgg gatgggtgag gacttcctga gctggaatga cctgcaggcc
1561 accgtgagcc aggtcaatgc acagacccag gaagagactg accgggtcct tgcagtcagc
1621 ctcatcaatg aggctctgga caaaggcagc cctgagaaga ctctgtctgc cctactgctt
1681 cctgcagctg gcctagatga tgtcagcctc cctgtcgccc ctcggtacca tctcctcctt
1741 gtggcagcca aaaggcagaa ggcccaggtg acaggggatc ctggagctgt gctgtggctt
1801 gaggagatcc gccagggagt ggtcagagcc aaccaggaca ctaatacagc tcagagaatg
1861 gctcttggtg tggctgccat caatcaagcc atcaaggagg gcaaggcagc ccagactgag
1921 cgggtgttga ggaaccccgc agtggccctt cgaggggtag ttcccgactg tgccaacggc
1981 taccagcgag ccctggaaag tgccatggca aagaaacagt gtccagcaga cacagctttc
2041 tgggttcaac atgacatgaa ggatggcact gcctactact tccatctgca gaccttccag
2101 gggatctggg agcaacctcc tggctgcccc ctcaacacct ctcacctgac ccgggaggag
2161 atccagtcag ctgtcaccaa ggtcactgct gcctatgacc gccaacagct ctggaaagcc
2221 aacgtcggct ttgttatcca gctccaggcc cgcctccgtg gcttcctagt tcggcagaag
2281 tttgctgagc attcccactt tctgaggacc tggctcccag cagtcatcaa gatccaggct
2341 cattggcggg gttataggca gcggaagatt tacctggagt ggttgcagta ttttaaagca
2401 aacctggatg ccataatcaa gatccaggcc tgggcccgga tgtgggcagc tcggaggcaa
2461 tacctgaggc gtctgcacta cttccagaag aatgttaact ccattgtgaa gatccaggca
2521 tttttccgag ccaggaaagc ccaagatgac tacaggatat tagtgcatgc accccaccct
2581 cctctcagtg tggtacgcag atttgcccat ctcttgaatc aaagccagca agacttcttg
2641 gctgaggcag agctgctgaa gctccaggaa gaggtagtta ggaagatccg atccaatcag
2701 cagctggagc aggacctcaa catcatggac atcaagattg gcctgctggt gaagaaccgg
2761 atcactctgc aggaagtggt ctcccactgc aagaagctga ccaagaggaa taaggaacag
2821 ctgtcagata tgatggttct ggacaagcag aagggtttaa agtcgctgag caaagagaaa
2881 cggcagaaac tagaagcata ccaacacctc ttctacctgc tccagactca gcccatctac
2941 ctggccaagc tgatctttca gatgccacag aacaaaacca ccaagttcat ggaggcagtg
3001 attttcagcc tgtacaacta tgcctccagc cgccgagagg cctatctcct gctccagctg
3061 ttcaagacag cactccagga ggaaatcaag tcaaaggtgg agcagcccca ggacgtggtg
3121 acaggcaacc caacagtggt gaggctggtg gtgagattct accgtaatgg gcggggacag
3181 agtgccctgc aggagattct gggcaaggtt atccaggatg tgctagaaga caaagtgctc
3241 agcgtccaca cagaccctgt ccacctctat aagaactgga tcaaccagac tgaggcccag
3301 acagggcagc gcagccatct cccatatgat gtcaccccgg agcaggcctt gagccacccc
3361 gaggtccaga gacgactgga catcgcccta cgcaacctcc tcgccatgac tgataagttc
3421 cttttagcca tcacctcatc tgtggaccaa attccgtatg ggatgcgata tgtggccaaa
3481 gtcctgaagg caactctggc agagaaattc cctgacgcca cagacagcga ggtctataag
3541 gtggtcggga acctcctgta ctaccgcttc ctgaacccag ctgtggtggc tcctgacgcc
3601 ttcgacattg tggccatggc agctggtgga gccctggctg ccccccagcg ccatgccctg
3661 ggggctgtgg ctcagctcct acagcacgct gcggctggca aggccttctc tgggcagagc
3721 cagcacctac gggtcctgaa tgactatctg gaggaaacac acctcaagtt caggaagttc
3781 atccatagag cctgccaggt gccagagcca gaggagcgtt ttgcagtgga cgagtactca
3841 gacatggtgg ctgtggccaa acccatggtg tacatcaccg tgggggagct ggtcaacacg
3901 cacaggctgt tgctggagca ccaggactgc attgcccctg atcaccaaga ccccctgcat
3961 gagctcctgg aggatcttgg ggagctgccc accatccctg accttattgg tgagagcatc
4021 gctgcagatg ggcacacgga cctgagcaag ctagaagtgt ccctgacgct gaccaacaag
4081 tttgaaggac tagaggcaga tgctgatgac tccaacaccc gtagcctgct tctgagcacc
4141 aagcagctgt tggccgatat catacagttc catcctgggg acaccctcaa ggagatcctg
4201 tccctctcgg cttccagaga gcaagaagca gcccacaagc agctgatgag ccgacgccag
4261 gcctgtacag cccagacacc ggagccactg cgacgacacc gctcactgac agctcactcc
4321 ctcctgccac tggcagagaa gcagcggcgc gtcctgcgga acctgcgccg acttgaagcc
4381 ctggggttgg tcagcgccag aaatggctac caggggctag tggacgagct ggccaaggac
4441 atccgcaacc agcacagaca caggcacagg cggaaggcag agctggtgaa gctgcaggcc
4501 acattacagg gcctgagcac taagaccacc ttctatgagg agcagggtga ctactacagc
4561 cagtacatcc gggcctgcct ggaccacctg gcccccgact ccaagagttc tgggaagggg
4621 aagaagcagc cttctcttca ttacactgct gctcagctcc tggaaaaggg tgtcttggtg
4681 gaaattgaag atcttcccgc ctctcacttc agaaacgtca tctttgacat cacgccggga
4741 gatgaggcag gaaagtttga agtaaatgcc aagttcctgg gtgtggacat ggagcgattt
4801 cagcttcact atcaggatct cctgcagctc cagtatgagg gtgtggctgt catgaaactc
4861 ttcaacaagg ccaaagtcaa tgtcaacctt ctcatcttcc tcctcaacaa gaagtttttg
4921 cggaagtgac agaggcaaag ggtgctaccc aagcccctct tacctctctg gatgctttct
4981 ttaacactaa ctcaccactg tgcttccctg cagacaccca gagctcagga ctgggcaagg
5041 cccagggatt ctcacccctt ccccagctgg gaggagcttg cctgcctggc cacagacagt
5101 gtatcttcta attggctaaa gtgggccttg cccagagtcc agctgtgtgg cttttatcat
5161 gcatgacaaa cccctggctt tcctgccaga tggtaggaca tggaccttga cctgggaaag
5221 ccattactct tgtgtctgct actgccctcc caagtcacc
//