LOCUS BC130522 3310 bp mRNA linear HUM 04-JAN-2007
DEFINITION Homo sapiens receptor tyrosine kinase-like orphan receptor 2, mRNA
(cDNA clone MGC:163394 IMAGE:40146553), complete cds.
ACCESSION BC130522
VERSION BC130522.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3310)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3310)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 8 Row: K Column: 9.
FEATURES Location/Qualifiers
source 1..3310
/db_xref="H-InvDB:HIT000390312"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:163394 IMAGE:40146553"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: TCCCGCCG"
gene 1..3310
/gene="ROR2"
/db_xref="GeneID:4920"
/db_xref="HGNC:HGNC:10257"
/db_xref="MIM:602337"
CDS 88..2919
/gene="ROR2"
/codon_start=1
/product="receptor tyrosine kinase-like orphan receptor 2"
/protein_id="AAI30523.1"
/db_xref="GeneID:4920"
/db_xref="HGNC:HGNC:10257"
/db_xref="MIM:602337"
/translation="MARGSALPRRPLLCIPAVWAAAALLLSVSRTSGEVEVLDPNDPL
GPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLKNDAPV
VQEPRRIIIRKTEYGSRLRIQDLDTTDTGYYQCVATNGMKTITATGVLFVRLGPTHSP
NHNFQDDYHEDGFCQPYRGIACARFIGNRTIYVDSLQMQGEIENRITAAFTMIGTSTH
LSDQCSQFAIPSFCHFVFPLCDARSRAPKPRELCRDECEVLESDLCRQEYTIARSNPL
ILMRLQLPKCEALPMPESPDAANCMRIGIPAERLGRYHQCYNGSGMDYRGTASTTKSG
HQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGPWCFTQNKNVRMELCDVP
SCSPRDSSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQ
DMEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQAVAIKT
LKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLV
MRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVY
DKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVL
WEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFK
DIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQKAPPFPQ
PQFIPMKGQIRPMVPPPQLYIPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQVPPQMV
PKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTVQEAEE
EEEGSVPETELLGDCDTLQVDEAQVQLEA"
BASE COUNT 701 a 1059 c 966 g 584 t
ORIGIN
1 ggacgcatcg tagaaagggg tggtggcgcc cgaccccgcg ccccggcccg aagctctgag
61 ggcttcccgg cccccactgc ctgcggcatg gcccggggct cggcgctccc gcggcggccg
121 ctgctgtgca tcccggccgt ctgggcggcc gccgcgcttc tgctctcagt gtcccggact
181 tcaggtgaag tggaggttct ggatccgaac gaccctttag gaccccttga tgggcaggac
241 ggcccgattc caactctgaa aggttacttt ctgaattttc tggagccagt aaacaatatc
301 accattgtcc aaggccagac ggcaattctg cactgcaagg tggcaggaaa cccaccccct
361 aacgtgcggt ggctaaagaa tgatgccccg gtggtgcagg agccgcggcg gatcatcatc
421 cggaagacag aatatggttc acgactgcga atccaggacc tggacacgac agacactggc
481 tactaccagt gcgtggccac caacgggatg aagaccatta ccgccactgg cgtcctgttt
541 gtgcggctgg gtccaacgca cagcccaaat cataactttc aggatgatta ccacgaggat
601 gggttctgcc agccttaccg gggaattgcc tgtgcacgct tcattggcaa ccggaccatt
661 tatgtggact cgcttcagat gcagggggag attgaaaacc gaatcacagc ggccttcacc
721 atgatcggca cgtctacgca cctgtcggac cagtgctcac agttcgccat cccatccttc
781 tgccacttcg tgtttcctct gtgcgacgcg cgctcccggg cacccaagcc gcgtgagctg
841 tgccgcgacg agtgcgaggt gctggagagc gacctgtgcc gccaggagta caccatcgcc
901 cgctccaacc cgctcatcct catgcggctt cagctgccca agtgtgaggc gctgcccatg
961 cctgagagcc ccgacgctgc caactgcatg cgcattggca tcccagccga gaggctgggc
1021 cgctaccatc agtgctataa cggctcaggc atggattaca gaggaacggc aagcaccacc
1081 aagtcaggcc accagtgcca gccgtgggcc ctgcagcacc cccacagcca ccacctgtcc
1141 agcacagact tccctgagct tggagggggg cacgcctact gccggaaccc cggaggccag
1201 atggagggcc cctggtgctt tacgcagaat aaaaacgtac gcatggaact gtgtgacgta
1261 ccctcgtgta gtccccgaga cagcagcaag atggggattc tgtacatctt ggtccccagc
1321 atcgcaattc cactggtcat cgcttgcctt ttcttcttgg tttgcatgtg ccggaataag
1381 cagaaggcat ctgcgtccac accgcagcgg cgacagctga tggcctcgcc cagccaagac
1441 atggaaatgc ccctcattaa ccagcacaaa caggccaaac tcaaagagat cagcctgtct
1501 gcggtgaggt tcatggagga gctgggagag gaccggtttg ggaaagtcta caaaggtcac
1561 ctgttcggcc ctgccccggg ggagcagacc caggctgtgg ccatcaaaac gctgaaggac
1621 aaagcggagg ggcccctgcg ggaggagttc cggcatgagg ctatgctgcg agcacggctg
1681 caacacccca acgtcgtctg cctgctgggc gtggtgacca aggaccagcc cctgagcatg
1741 atcttcagct actgttcgca cggcgacctc cacgaattcc tggtcatgcg ctcgccgcac
1801 tcggacgtgg gcagcaccga tgatgaccgc acggtgaagt ccgccctgga gccccccgac
1861 ttcgtgcacc ttgtggcaca gatcgcggcg gggatggagt acctatccag ccaccacgtg
1921 gttcacaagg acctggccac ccgcaatgtg ctagtgtacg acaagctgaa cgtgaagatc
1981 tcagacttgg gcctcttccg agaggtgtat gccgccgatt actacaagct gctggggaac
2041 tcgctgctgc ctatccgctg gatggcccca gaggccatca tgtacggcaa gttctccatc
2101 gactcagaca tctggtccta cggtgtggtc ctgtgggagg tcttcagcta cggcctgcag
2161 ccctactgcg ggtattccaa ccaggatgtg gtggagatga tccggaaccg gcaggtgctg
2221 ccttgccccg atgactgtcc cgcctgggtg tatgccctca tgatcgagtg ctggaacgag
2281 ttccccagcc ggcggccccg cttcaaggac atccacagcc ggctccgagc ctggggcaac
2341 ctttccaact acaacagctc ggcgcagacc tcgggggcca gcaacaccac gcagaccagc
2401 tccctgagca ccagcccagt gagcaatgtg agcaacgccc gctacgtggg gcccaagcag
2461 aaggccccgc ccttcccaca gccccagttc atccccatga agggccagat cagacccatg
2521 gtgcccccgc cgcagctcta catccccgtc aacggctacc agccggtgcc ggcctatggg
2581 gcctacctgc ccaacttcta cccggtgcag atcccaatgc agatggcccc gcagcaggtg
2641 cctcctcaga tggtccccaa gcccagctca caccacagtg gcagtggctc caccagcaca
2701 ggctacgtca ccacggcccc ctccaacaca tccatggcag acagggcagc cctgctctca
2761 gagggcgctg atgacacaca gaacgcccca gaagatgggg cccagagcac cgtgcaggaa
2821 gcagaggagg aggaggaagg ctctgtccca gagactgagc tgctggggga ctgtgacact
2881 ctgcaggtgg acgaggccca agtccagctg gaagcttgag tggcaccagg gcccagggtt
2941 cggggataga agccccgccg agaccccaca gggacctcag tcacctttga gaagacacca
3001 tactcagcaa tcacaagagc ccgccggcca gtgggcttgt ttgcagactg ggtgaggtgg
3061 agccctgctc ctctctgtcc tctgacacag ctgccctgcc taggagcacc caagccaggc
3121 agggggtctg gcagcacggc gtcctgggga gcaggacaca tggtcatccc cagggctgta
3181 tacattgatt ctggtggtag actggtagtg agcagcaaat gcctttcaag aaaataggtg
3241 gcagcttcac tccatgtcat atatggagtg aatatttcaa aacgttggga ataagggcct
3301 gcaaaaggca
//