LOCUS BC130476 2649 bp mRNA linear HUM 04-JAN-2007
DEFINITION Homo sapiens myeloperoxidase, mRNA (cDNA clone MGC:163348
IMAGE:40146507), complete cds.
ACCESSION BC130476
VERSION BC130476.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2649)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2649)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (04-JAN-2007) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 8 Row: I Column: 11.
FEATURES Location/Qualifiers
source 1..2649
/db_xref="H-InvDB:HIT000390266"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:163348 IMAGE:40146507"
/tissue_type="Pooled, cerebellum, kidney, placenta,
testis, lung, colon, liver, heart, thyroid, bladder,
uterus, PCR rescued clones"
/clone_lib="NIH_MGC_362"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: TATTGCAT"
gene 1..2649
/gene="MPO"
/db_xref="GeneID:4353"
/db_xref="HGNC:HGNC:7218"
/db_xref="MIM:606989"
CDS 52..2289
/gene="MPO"
/codon_start=1
/product="myeloperoxidase"
/protein_id="AAI30477.1"
/db_xref="GeneID:4353"
/db_xref="HGNC:HGNC:7218"
/db_xref="MIM:606989"
/translation="MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQ
PSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRESIKQRLRSGSASPMELLSYF
KQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAY
QDVGVTCPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVK
RNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFV
TGVNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALT
SFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNR
SARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIV
GAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPF
MFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVD
EIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNL
KLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWEN
EGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLAS
WREAS"
BASE COUNT 525 a 813 c 785 g 526 t
ORIGIN
1 tgaggtgggg ctgaggtaca aagggggatt gagcagccca ggagaagaga gatgggggtt
61 cccttcttct cttctctcag atgcatggtg gacttaggac cttgctgggc tgggggtctc
121 actgcagaga tgaagctgct tctggcccta gcagggctcc tggccattct ggccacgccc
181 cagccctctg aaggtgctgc tccagctgtc ctgggggagg tggacacctc gttggtgctg
241 agctccatgg aggaggccaa gcagctggtg gacaaggcct acaaggagcg gcgggaaagc
301 atcaagcagc ggcttcgcag cggctcagcc agccccatgg aactcctatc ctacttcaag
361 cagccggtgg cagccaccag gacggcggtg agggccgctg actacctgca cgtggctcta
421 gacctgctgg agaggaagct gcggtccctg tggcgaaggc cattcaatgt cactgatgtg
481 ctgacgcccg cccagctgaa tgtgttgtcc aagtcaagcg gctgcgccta ccaggacgtg
541 ggggtgactt gcccggagca ggacaaatac cgcaccatca ccgggatgtg caacaacaga
601 cgcagcccca cgctgggggc ctccaaccgt gcctttgtgc gctggctgcc ggcggagtat
661 gaggacggct tctctcttcc ctacggctgg acgcccgggg tcaagcgcaa cggcttcccg
721 gtggctctgg ctcgcgcggt ctccaacgag atcgtgcgct tccccactga tcagctgact
781 ccggaccagg agcgctcact catgttcatg caatggggcc agctgttgga ccacgacctc
841 gacttcaccc ctgagccggc cgcccgggcc tccttcgtca ctggcgtcaa ctgcgagacc
901 agctgcgttc agcagccgcc ctgcttcccg ctcaagatcc cgcccaatga cccccgcatc
961 aagaaccaag ccgactgcat cccgttcttc cgctcctgcc cggcttgccc cgggagcaac
1021 atcaccatcc gcaaccagat caacgcgctc acttccttcg tggacgccag catggtgtac
1081 ggcagcgagg agcccctggc caggaacctg cgcaacatgt ccaaccagct ggggctgctg
1141 gccgtcaacc agcgcttcca agacaacggc cgggccctgc tgccctttga caacctgcac
1201 gatgacccct gtctcctcac caaccgctca gcgcgcatcc cctgcttcct ggcaggggac
1261 acccgttcca gtgagatgcc cgagctcacc tccatgcaca ccctcttact tcgggagcac
1321 aaccggctgg ccacagagct caagagcctg aaccctaggt gggatgggga gaggctctac
1381 caggaagccc ggaagatcgt gggggccatg gtccagatca tcacttaccg ggactacctg
1441 cccctggtgc tggggccaac ggccatgagg aagtacctgc ccacgtaccg ttcctacaat
1501 gactcagtgg acccacgcat cgccaacgtc ttcaccaatg ccttccgcta cggccacacc
1561 ctcatccaac ccttcatgtt ccgcctggac aatcggtacc agcccatgga acccaacccc
1621 cgtgtccccc tcagcagggt cttttttgcc tcctggaggg tcgtgctgga aggtggcatt
1681 gaccccatcc tccggggcct catggccacc cctgccaagc tgaatcgtca gaaccaaatt
1741 gcagtggatg agatccggga gcgattgttt gagcaggtca tgaggattgg gctggacctg
1801 cctgctctga acatgcagcg cagcagggac cacggcctcc caggatacaa tgcctggagg
1861 cgcttctgtg ggctcccgca gcctgaaact gtgggccagc tgggcacggt gctgaggaac
1921 ctgaaattgg cgaggaaact gatggagcag tatggcacgc ccaacaacat cgacatctgg
1981 atgggcggcg tgtccgagcc tctgaagcgc aaaggccgcg tgggcccact cctcgcctgc
2041 atcatcggta cccagttcag gaagctccgg gatggtgatc ggttttggtg ggagaacgag
2101 ggtgtgttca gcatgcagca gcgacaggcc ctggcccaga tctcattgcc ccggatcatc
2161 tgcgacaaca caggcatcac caccgtgtct aagaacaaca tcttcatgtc caactcatat
2221 ccccgggact ttgtcaactg cagtacactt cctgcattga acctggcttc ctggagggaa
2281 gcctcctaga ggccaggtaa gggggtgcag cagtgagggg tatatctggg ctggccagtt
2341 ggaaccacgg agatctcctt gccctagatg agcccagccc tgttctgggt gcagctgaga
2401 aaatgagtga ctagacgttc atttgtgtgc tcatgtatgt gcgaagtata taaattggct
2461 tttcatgcgt gtgtgttgtc tgaacatggg gagtgtttca tgggttatgt gtatgtgcca
2521 tttatgtgag tgtgtgtttg tgctgatgag aatactgagt atgtggaagg cagcagagcg
2581 gactggtgag gagcacagct caggaactag actgcctggg ttccaatcct ggctctgtgg
2641 cttgctagc
//