LOCUS BC129948 3988 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens tetratricopeptide repeat domain 21A, mRNA (cDNA clone
MGC:156293 IMAGE:40126472), complete cds.
ACCESSION BC129948
VERSION BC129948.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3988)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3988)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-DEC-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 30 Row: p Column: 7
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..3988
/db_xref="H-InvDB:HIT000390021"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:156293 IMAGE:40126472"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: TTATTTTT sequenced from the reverse primer"
gene 1..3988
/gene="TTC21A"
/gene_synonym="STI2"
/db_xref="GeneID:199223"
/db_xref="HGNC:HGNC:30761"
/db_xref="MIM:611430"
CDS 110..3541
/gene="TTC21A"
/gene_synonym="STI2"
/codon_start=1
/product="TTC21A protein"
/protein_id="AAI29949.1"
/db_xref="GeneID:199223"
/db_xref="HGNC:HGNC:30761"
/db_xref="MIM:611430"
/translation="MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFF
KAYGVLKEEHIQDAISDLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLK
EIRKTVSGTALYYAGLFLWLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKP
HTAKKAIEYLEQGIQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALV
LKMQLFLARQDWEQTVEMGHRILEKDESNIDACQILTVHELAREGNMTTATNHVRNLI
KALETREPENPSLHLKKIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGY
LFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKS
LGKSEVLIFLQALLMSRKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFL
VCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSG
ELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPL
YHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELVE
ALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPK
QSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPEKA
LEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLGKLL
LKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKAL
DLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPT
DNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINL
YHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIY
CWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVVGGEAFENQGAESNYM
EKKELEQQGVSTAEKLLQGQRPCPAGLGTSLRVPEADPQGAYAVEAPGQDPLGAE"
BASE COUNT 1065 a 1028 c 1063 g 832 t
ORIGIN
1 tgtaacgcct tcaaccgccc gccgcgatag agtgcccacg accctgcctc gggaatcccg
61 ctctgcaccg ccccaccaga cccggactcg gagccgcgag cggcccgaga tgagcagcaa
121 tgactcctcc cttatggctg ggatcattta ctatagccag gaaaagtact tccaccatgt
181 gcagcaggct gcagctgtgg gcctggaaaa attcagcaat gaccctgtgt tgaagttctt
241 taaagcctat ggagtcctca aagaagagca catccaggat gccatcagtg acctggaaag
301 catcaggcat cacccagacg tgtccctgtg ctccaccatg gccctcattt atgctcacaa
361 aagatgtgaa atcattgacc gagaagcaat tcaggagctt gagtacagcc tgaaggaaat
421 acgcaagaca gtcagtggga ctgcactgta ctatgctggc cttttcctct ggctcatagg
481 ccgccatgac aaggccaaag agtacattga ccgcatgctg aagatttcta gaggcttcag
541 agaggcctat gtgctcagag gctgggtgga cctgacctca gacaagcccc acactgcgaa
601 gaaagccatt gagtacctgg aacaaggaat tcaggacacc aaagatgtgc tggggctgat
661 gggaaaggca atgtacttca tgatgcagca gaactactca gaggccctgg aggtggtgaa
721 ccagatcact gtgacttcag ggagcttcct gccagccctc gtcctgaaga tgcagctgtt
781 cttagctcgg caggactggg agcagacagt agaaatggga cacagaatcc tagaaaaaga
841 tgagagcaat attgatgcct gccaaattct aaccgtgcat gagcttgcaa gagaaggaaa
901 catgaccaca gctaccaatc acgttagaaa tctgattaag gcactagaga caagggaacc
961 cgaaaatcca agcctccatc ttaaaaaaat tattgtggtt agccgactgt gtgggagtca
1021 ccaggtgatt ctagggctag tgtgtagttt catcgagcgc accttcatgg ccaccccctc
1081 gtatgtccat gtggccacag aactgggcta tctcttcatc ctgaagaacc aagtgaaaga
1141 ggccttgctg tggtattcag aagccatgaa actggacaag gatggcatgg ctggtttgac
1201 agggatcatc ttgtgtcata tcttagaagg ccacctggag gaagctgagt accggctgga
1261 attcctgaag gaggtgcaga agtcccttgg gaagtctgag gtgctaattt tcctccaagc
1321 cctcctgatg tccaggaagc acaaggggga ggaagagacc acagcgctcc tgaaggaggc
1381 agtggagctt cacttctcca gcatgcaagg catccctctt ggctctgagt actttgaaaa
1441 gctggacccg tacttcctgg tctgcattgc taaggagtac ttgctcttct gccccaagca
1501 gcccaggtta ccaggccaga tcgtgtctcc acttcttaaa caagtcgccg tgatcttgaa
1561 tcctgtagtc aaagcagcac cagctctgat cgaccccctg tatttgatgg ctcaggtcag
1621 gtattactca ggagagctag agaatgccca gagcatcctg cagcgttgcc tggagctgga
1681 ccccgcctcc gtggatgccc atctcctcat gtgtcagatc tacttggctc agggcaactt
1741 tggcatgtgc ttccactgct tagagctggg tgtcagccac aacttccagg tccgagatca
1801 ccccctctac cacctcatca aggccagggc cctcaacaag gctggagact atccagaggc
1861 cataaagacg ctgaaaatgg tcatcaaatt gccagctctg aagaaggaag aaggcagaaa
1921 gttcctcagg ccctctgtgc agcctagcca gcgggcatcc atcttattgg aactggtgga
1981 ggccctccgg ctgaatgggg agctacatga ggccaccaag gtcatgcagg acaccatcaa
2041 tgagttcggt ggcacaccag aagagaaccg catcaccatt gccaacgtgg acttggtcct
2101 gagcaagggc aatgtggacg tggcgctgaa catgctaagg aacatcttgc ccaagcagtc
2161 ctgctatatg gaagccagag agaagatggc caacatctac ctgcagaccc tcagagacag
2221 gcgcctctac atcagatgct accgtgagct ctgtgaacat ctgcctggcc cccacaccag
2281 cctgctactg ggcgatgcct taatgagcat tctggagccc gagaaggccc tggaggtcta
2341 tgatgaggcc tatagacaga acccacatga cgcctccctg gccagcagaa ttgggcacgc
2401 ttatgtgaag gcccaccagt atactgaggc aattgagtat tatgaggctg cccagaagat
2461 taatggacag gactttctgt gctgcgatct gggcaaactg ctcctgaagt taaagaaggt
2521 caataaagca gaaaaagttt tgaagcaggc actggaacat gacattgtcc aagacatccc
2581 atccatgatg aatgatgtta agtgcctgct tttgctggca aaggtttaca agagccataa
2641 aaaagaagct gtgatagaaa ctttgaacaa ggccttggac ctccagtctc ggatactgaa
2701 gcgagttcca ctggagcaac cagaaatgat tccctcccag aagcaactgg cagcctctat
2761 ctgcatccaa tttgcagagc actacctggc agagaaagag tatgacaagg cggtacagtc
2821 ttataaggat gtcttctcct acttgccaac tgacaataag gtgatgctgg agctggcgca
2881 gctctacctg ctccaggggc acctggacct gtgtgagcag cactgtgcca tcctcctgca
2941 gactgagcag aaccatgaga ccgcttctgt gttgatggct gacctgatgt ttagaaaaca
3001 gaaacatgaa gcggccatca atctttacca ccaagtcttg gagaaagcgc cagacaattt
3061 tttggtattg cataaattaa tcgatctgct aagaagaagt ggaaaacttg aagacattcc
3121 tgccttcttt gaattggcca agaaggtgtc tagccgggtg cctttggaac cagggttcaa
3181 ttactgcaga ggtatctact gctggcacat agggcagccc aacgaagcct taaagttcct
3241 gaacaaggca cgcaaggaca gcacttgggg ccagagcgcc atctaccaca tggtgcagat
3301 ctgtctgaat ccagacaacg aggttgtggg cggagaggct tttgagaacc agggagctga
3361 gagcaactac atggagaaga aggagttgga gcagcagggt gtgagcaccg ccgagaaact
3421 gctgcaagga cagcgtccct gccctgctgg ccttggcaca agcctacgtg ttcctgaagc
3481 agatccccaa ggcgcgtatg cagttgaagc gcctggccaa gaccccctgg gtgctgagtg
3541 aggctgagga cctggagaag agctggctcc tgctggctga catttactgc cagggcagca
3601 agttcgacct cgccttagaa ctgctgcggc gctgtgtgca atacaacaag tcctgctaca
3661 aggcctatga gtacatgggc ttcatcatgg agaaggagca gtcctacaag gatgcagtca
3721 ccaactacaa actggcctgg aagtacagtc atcacgccaa ccctgccatt ggcttcaaac
3781 ttgctttcaa ctacctgaag gacaagaaat ttgtggaggc catcgaaatc tgcaacgatg
3841 tcctcaggga gcaccccgac taccccaaga tcagggagga aattttggaa aaggcccgaa
3901 ggtccctgag gccctagctg gggtcaaggg gcctggacca gtagaagcca tcaacctact
3961 gaagttgtgt ggagggatgg aaagtggg
//