LOCUS BC129927 4698 bp mRNA linear HUM 02-JAN-2007
DEFINITION Homo sapiens PH domain and leucine rich repeat protein
phosphatase-like, mRNA (cDNA clone MGC:150693 IMAGE:40124720),
complete cds.
ACCESSION BC129927
VERSION BC129927.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4698)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4698)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-DEC-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 30 Row: p Column: 1.
FEATURES Location/Qualifiers
source 1..4698
/db_xref="H-InvDB:HIT000390000"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:150693 IMAGE:40124720"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: GTTTATC sequenced from the reverse primer"
gene 1..4698
/gene="PHLPPL"
/db_xref="GeneID:23035"
/db_xref="HGNC:HGNC:29149"
CDS 7..3978
/gene="PHLPPL"
/codon_start=1
/product="PH domain and leucine rich repeat protein
phosphatase-like"
/protein_id="AAI29928.1"
/db_xref="GeneID:23035"
/db_xref="HGNC:HGNC:29149"
/translation="MKRNGSRNCLNRRSRFGSRERDWLREDVKRGCVYLYGADTTTAT
TTTTTSSSSSSSSSSSDLHLVLCTVETPASEICAGEGRESLYLQLHGDLVRRLEPTER
PLQIVYDYLSRLGFDDPVRIQEEATNPDLGCMIRFYGEKPCHMDRLDRILLSGIYNVR
KGKTQLHKWAERLVVLCGTCLIVSSVKDCQTGKMHILPLVGGKIEEVKRRQYSLAFSS
AGAQAQTYHVSFETLAEYQRWQRQASKVVSQRISTVDLSCYSLEEVPEHLFYSQDITY
LNLRHNFMQLERPGGLDTLYKFSQLKGLNLSHNKLGLFPILLCEISTLTELNLSCNGF
HDLPSQIGNLLNLQTLCLDGNFLTTLPEELGNLQQLSSLGISFNNFSQIPEVYEKLTM
LDRVVMAGNCLEVLNLGVLNRMNHIKHVDLRMNHLKTMVIENLEGNKHITHVDLRDNR
LTDLDLSSLCSLEQLHCGRNQLRELTLSGFSLRTLYASSNRLTAVNVYPVPSLLTFLD
LSRNLLECVPDWACEAKKIEVLDVSYNLLTEVPVRILSSLSLRKLMLGHNHVQNLPTL
VEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNASANSLESLPSACTGEESLSMLQL
LYLTNNLLTDQCIPVLVGHLHLRILHLANNQLQTFPASKLNKLEQLEELNLSGNKLKT
IPTTIANCKRLHTLVAHSNNISIFPEILQLPQIQFVDLSCNDLTEILIPEALPATLQD
LDLTGNTNLVLEHKTLDIFSHITTLKIDQKPLPTTDSTVTSTFWSHGLAEMAGQRNKL
CVSALAMDSFAEGVGAVYGMFDGDRNEELPRLLQCTMADVLLEEVQQSTNDTVFMANT
FLVSHRKLGMAGQKLGSSALLCYIRPDTADPASSFSLTVANVGTCQAVLCRGGKPVPL
SKVFSLEQDPEEAQRVKDQKAIITEDNKVNGVTCCTRMLGCTYLYPWILPKPHISSTP
LTIQDELLILGNKALWEHLSYTEAVNAVRHVQDPLAAAKKLCTLAQSYGCQDNVGAMV
VYLNIGEEGCTCEMNGLTLPGPVGFASTTTIKDAPKPATPSSSSGIASEFSSEMSTSE
VSSEVGSTASDEHNAGGLDTALLPRPERRCSLHPTPTSGLFQRQPSSATFSSNQSDNG
LDSDDDQPVEGVITNGSKVEVEVDIHCCRGRDLENSPPLIESSPTLCSEEHARGSCFG
IRRQNSVNSGMLLPMSKDRMELQKSPSTSCLYGKKLSNGSIVPLEDSLNLIEVATEVP
KRKTGYFAAPTQMEPEDQFVVPHDLEEEVKEQMKQHQDSRLEPEPHEEDQTEPPEEFD
TAL"
BASE COUNT 1200 a 1163 c 1150 g 1185 t
ORIGIN
1 agaaatatga aacgcaatgg gagcagaaat tgtttgaata ggagaagtag gtttggttct
61 cgagaaagag actggctaag agaagatgta aagagaggct gtgtttacct ttatggagca
121 gacactacca ctgccactac aaccaccacc acctcctctt cctcttcctc ctcctcctct
181 tcctctgact tacatctcgt cctttgcact gtagagacac cagcatcaga aatatgtgct
241 ggagagggaa gagaaagtct ttatttacag cttcatggag acctggtcag gagactggaa
301 cctactgaac gacctcttca gatcgtttat gattacttat ccaggctggg atttgatgat
361 cctgtgcgca tacaggagga ggctacaaat cctgacctcg gctgtatgat tcgattttat
421 ggtgaaaaac catgccacat ggatcgtttg gatcgaatcc tattgtctgg catctataat
481 gtacgcaagg gaaagaccca gctgcataag tgggctgagc gcctagttgt cctctgtggt
541 acctgcctta tcgtttcctc agtgaaggat tgtcaaactg gaaagatgca cattttgcct
601 ctggttggtg gaaagataga agaagtgaag cgacggcaat actcccttgc tttcagctca
661 gcaggagccc aagctcagac ctatcatgtc agcttcgaga ctttggccga gtaccagcga
721 tggcaacggc aagcatccaa ggtggtgtcc cagcgaatca gtaccgtgga tctctcgtgt
781 tacagcctcg aggaggttcc tgagcatctc ttctatagtc aagatattac ctacctcaac
841 ttgcgacaca acttcatgca gttagaaaga cccggaggcc tcgatacact ctacaaattt
901 tctcaactga agggcctgaa cttgtcccat aataaacttg ggttgtttcc tatattgtta
961 tgcgagatct ctaccctgac tgagctcaac ctttcctgta atggatttca tgacctacca
1021 agtcaaattg gcaatctgct aaatcttcaa accctctgtc ttgatggcaa ctttctgact
1081 actttacctg aagaattggg aaatctacaa cagctttcct ccttgggaat ttccttcaac
1141 aactttagtc aaattcctga ggtttatgag aaactcacta tgttagatag agtggttatg
1201 gcaggaaatt gcctggaagt cctgaactta ggggtgctga ataggatgaa ccatatcaag
1261 catgtggatt taaggatgaa ccatttgaaa accatggtta ttgaaaatct ggagggaaat
1321 aaacacatca cccacgtgga tctgcgggac aaccgactga ctgacttgga tcttagctcc
1381 ttatgcagct tggaacagct gcactgtggg cggaatcagc tgagggagct aacactcagt
1441 ggcttttccc ttcggaccct ctatgccagt tccaacaggc tgacagcagt gaacgtctat
1501 ccagtaccca gcctgctcac tttcttggat ctctcccgaa acctgctaga gtgtgtccct
1561 gactgggcct gtgaagcaaa gaagatagaa gtattagatg tgagctataa tcttctcaca
1621 gaggttcccg tgagaattct gagtagcttg agtcttagaa aactgatgct gggacacaat
1681 catgtgcaaa accttccaac actggtagag cacatccccc tcgaggtgct ggatcttcag
1741 cataatgcac tcacgaggct gccagacacc ctcttctcca aggccttaaa tctcagatac
1801 ttgaatgcat ctgcaaatag tctggagtct ttaccatccg cctgcactgg agaggagagt
1861 ttgagtatgc tgcagctgct ttatctgacc aacaatctcc tgacggatca gtgcatacct
1921 gtcctggtag ggcacctgca cctgcgaatc ttgcaccttg caaacaatca gttacagacc
1981 tttcctgcaa gcaaactaaa taaattggag caattggagg aactgaacct aagtggcaac
2041 aagcttaaaa ccattcccac aaccatagca aactgtaaaa ggctgcacac ccttgttgca
2101 cactccaaca acatcagcat tttcccagaa atactgcagt tgcctcagat ccagtttgta
2161 gacctaagtt gcaacgactt gacagaaatc ctgattccag aggctttgcc tgctacatta
2221 caagaccttg acctgactgg aaatacaaat ctggttctgg aacacaagac actggacata
2281 tttagccata tcacaaccct gaaaattgat cagaaacctt tgccaaccac agattctaca
2341 gttacgtcaa ccttctggag ccatggactg gctgagatgg cagggcagag aaataagctg
2401 tgtgtctcag cacttgctat ggatagcttt gcagaggggg tgggagctgt gtatggcatg
2461 tttgatggag accgaaatga ggagctcccg cgcctgctgc agtgtacgat ggcagatgtg
2521 cttttagaag aggtacagca gtcaactaat gacacagttt tcatggctaa caccttcttg
2581 gtatctcaca ggaaattagg aatggctggc cagaagttgg gctcctccgc tctcctgtgc
2641 tacatccgcc ctgacactgc cgatccagca agtagcttta gcttgactgt agccaatgtt
2701 ggcacgtgcc aagcagtcct gtgccgaggt gggaagccag tgcccctctc taaagtcttc
2761 agcctggagc aggacccaga ggaggctcaa agggtgaagg accaaaaagc catcatcaca
2821 gaggacaaca aagtgaatgg ggtaacctgc tgtacccgga tgctgggctg tacatacctc
2881 tacccttgga tcctccccaa gccccacata tcttccactc cgctgaccat tcaagatgag
2941 ttgctgattc tgggaaacaa agcattgtgg gaacacttgt cctacacaga agctgtcaat
3001 gctgtacgtc acgtacaaga cccattagca gctgctaaga agctgtgcac attagcgcag
3061 agctatggct gtcaggacaa tgtaggggcg atggtagttt atttgaatat tggtgaggaa
3121 ggctgcactt gtgaaatgaa tgggctcacc ctcccaggtc ctgtgggatt tgcttcaacc
3181 accactatca aggatgcccc taagccagcc actccatcct ctagcagtgg gattgcctct
3241 gagttcagca gtgagatgtc cacctcagag gtgagcagtg aagtggggtc cactgcttct
3301 gatgagcata atgctggggg cctggacact gccttgcttc cgaggccaga gcggcgctgc
3361 agcctccacc caacacccac ctctgggctg tttcagcgcc agccttcttc tgctaccttc
3421 tccagtaacc agtctgacaa cggcctggac agtgatgatg accagcccgt tgagggggtc
3481 ataaccaatg gcagcaaggt agaggtggaa gtagacatcc actgctgcag ggggagggat
3541 ctggagaact caccccctct catagagagt tctcctaccc tgtgttctga ggaacatgct
3601 agagggtcgt gttttgggat ccgaagacag aacagtgtga atagtggcat gctcctgcca
3661 atgagcaagg acaggatgga gttacagaag tctccctcca cctcctgcct ctatgggaag
3721 aaactctcca atggctctat tgtgccccta gaggacagcc tgaacctcat tgaagtggcc
3781 acagaagtgc ccaagaggaa aactggctat tttgctgccc ccactcagat ggaaccagag
3841 gaccagtttg ttgtgcctca tgacctggaa gaagaagtga aggaacaaat gaaacagcac
3901 caggacagcc ggctcgagcc tgagccccat gaagaggatc agaccgagcc cccggaggag
3961 ttcgacacag cactgtgact gccccactgg gcacagtgtg ggaggaggct gtgcagggtt
4021 ggggtaggga cttgctagag gcattctgcc tctacatttc tttttgtttg ttcgtttttt
4081 ttttgtttgt ttgttttgag acggagtctt gctcagtcgc tcaggctgga gtgcaatggt
4141 ggggtctcgg gtcactgcag cctctgtccc tgggttcaag ccattctcct gtctcagcct
4201 cccgagtagc tgggattaca ggcacctgcc attatgcccg gctaagtttt attttttttt
4261 ttagagacgg ggtttcacca tgttggccag gctggtgttg aactcttgac ctcaggtgat
4321 ccaccctcct ctgcctccca aagtgctgtg attacaggcc tcagccacca tgcccagccc
4381 tgcgtctaca tttctaaacc atagctgtgt ggggttgaac tcggagccaa aaagtgtgag
4441 agccatcagg ggctggctct ggataaactg gtagccacta tcagtgttaa gtttcacatt
4501 taacctgcat tggaattccc aggggtactg ggaagaaagc agctgttctg tatcagtcct
4561 accacctgcc attaaccctt tctctcctag gatcattttg agaatttgcc tgcctgggca
4621 ggaaagggac tatttctgtg gaggaaaaaa gtgaagattg attctcttta ctagttgctg
4681 ctgatggatc tctgtgat
//