LOCUS BC126428 2459 bp mRNA linear HUM 23-OCT-2006
DEFINITION Homo sapiens BRCA1 associated RING domain 1, mRNA (cDNA clone
MGC:161706 IMAGE:8992144), complete cds.
ACCESSION BC126428
VERSION BC126428.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2459)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2459)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 7 Row: N Column: 14.
FEATURES Location/Qualifiers
source 1..2459
/db_xref="H-InvDB:HIT000389020"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:161706 IMAGE:8992144"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: ACTTATTG"
gene 1..2459
/gene="BARD1"
/db_xref="GeneID:580"
/db_xref="HGNC:HGNC:952"
/db_xref="MIM:601593"
CDS 71..2404
/gene="BARD1"
/codon_start=1
/product="BRCA1 associated RING domain 1"
/protein_id="AAI26429.1"
/db_xref="GeneID:580"
/db_xref="HGNC:HGNC:952"
/db_xref="MIM:601593"
/translation="MPDNRQPRNRQPRIRSGNEPRSASAMEPDGRGAWAHSRAALDRL
EKLLRCSRCTNILREPVCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLD
SMIQLCSKLRNLLHDNELSDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSK
ASVQTQPAIKKDASAQQDSYEFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKW
NLEAEKEDGEFDSKEESKQKLVSFCSQPSVISSPQINGEIDLLASGSLTESECFGSLT
EVSLPLAEQIESPDTKSRNEVVTPEKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISK
RCRTSILSTSGDFVKQTVPSENIPLPECSSPPSCKRKVGGTSGSKNSNMSDEFISLSP
GTPPSTLSSSSYRRVMSSPSAMKLLPNMAVKRNHRGETLLHIASIKGDIPSVEYLLQN
GSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHMD
IVKLLLSYGASRNAVNIFGLRPVDYTDDESMKSLLLLPEKNESSSASHCSVMNTGQRR
DGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEFDSTVTHVVVPGDAVQSTLKCMLGI
LNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRSRLNREQLLPKLFDGCYFYLWGT
FKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTVAYHARPDSDQRFCTQYIIYE
DLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS"
BASE COUNT 743 a 513 c 575 g 628 t
ORIGIN
1 cttccctgtg gtttcccgag gcctccttgc ttcccgctct ccgaggagcc tttcatccga
61 aggcgggacg atgccggata atcggcagcc gaggaaccgg cagccgagga tccgctccgg
121 gaacgagcct cgttccgcgt ccgccatgga acctgatggt cgcggtgcct gggcccacag
181 tcgcgccgcg ctcgaccgcc tggagaagct gctgcgctgc tcgcgttgta ctaacattct
241 gagagagcct gtgtgtttag gaggatgtga gcacatcttc tgtagtaatt gtgtaagtga
301 ctgcattgga actggatgtc cagtgtgtta caccccggcc tggatacaag acttgaagat
361 aaatagacaa ctggacagca tgattcaact ttgtagtaag cttcgaaatt tgctacatga
421 caatgagctg tcagatttga aagaagataa acctaggaaa agtttgttta atgatgcagg
481 aaacaagaag aattcaatta aaatgtggtt tagccctcga agtaagaaag tcagatatgt
541 tgtgagtaaa gcttcagtgc aaacccagcc tgcaataaaa aaagatgcaa gtgctcagca
601 agactcatat gaatttgttt ccccaagtcc tcctgcagat gtttctgaga gggctaaaaa
661 ggcttctgca agatctggaa aaaagcaaaa aaagaaaact ttagctgaaa tcaaccaaaa
721 atggaattta gaggcagaaa aagaagatgg tgaatttgac tccaaagagg aatctaagca
781 aaagctggta tccttctgta gccaaccatc tgttatctcc agtcctcaga taaatggtga
841 aatagactta ctagcaagtg gctccttgac agaatctgaa tgttttggaa gtttaactga
901 agtctcttta ccattggctg agcaaataga gtctccagac actaagagca ggaatgaagt
961 agtgactcct gagaaggtct gcaaaaatta tcttacatct aagaaatctt tgccattaga
1021 aaataatgga aaacgtggcc atcacaatag actttccagt cccatttcta agagatgtag
1081 aaccagcatt ctgagcacca gtggagattt tgttaagcaa acggtgccct cagaaaatat
1141 accattgcct gaatgttctt caccaccttc atgcaaacgt aaagttggtg gtacatcagg
1201 gagcaaaaac agtaacatgt ccgatgaatt cattagtctt tcaccaggta caccaccttc
1261 tacattaagt agttcaagtt acaggcgagt gatgtctagt ccctcagcaa tgaagctgtt
1321 gcccaatatg gctgtgaaaa gaaatcatag aggagagact ttgctccata ttgcttctat
1381 taagggcgac ataccttctg ttgaatacct tttacaaaat ggaagtgatc caaatgttaa
1441 agaccatgct ggatggacac cattgcatga agcttgcaat catgggcacc tgaaggtagt
1501 ggaattattg ctccagcata aggcattggt gaacaccacc gggtatcaaa atgactcacc
1561 acttcacgat gcagccaaga atgggcacat ggatatagtc aagctgttac tttcctatgg
1621 agcctccaga aatgctgtta atatatttgg tctgcggcct gtcgattata cagatgatga
1681 aagtatgaaa tcgctattgc tgctaccaga gaagaatgaa tcatcctcag ctagccactg
1741 ctcagtaatg aacactgggc agcgtaggga tggacctctt gtacttatag gcagtgggct
1801 gtcttcagaa caacagaaaa tgctcagtga gcttgcagta attcttaagg ctaaaaaata
1861 tactgagttt gacagtacag taactcatgt tgttgttcct ggtgatgcag ttcaaagtac
1921 cttgaagtgt atgcttggga ttctcaatgg atgctggatt ctaaaatttg aatgggtaaa
1981 agcatgtcta cgaagaaaag tatgtgaaca ggaagaaaag tatgaaattc ctgaaggtcc
2041 acgcagaagc aggctcaaca gagaacagct gttgccaaag ctgtttgatg gatgctactt
2101 ctatttgtgg ggaaccttca aacaccatcc aaaggacaac cttattaagc tcgtcactgc
2161 aggtgggggc cagatcctca gtagaaagcc caagccagac agtgacgtga ctcagaccat
2221 caatacagtc gcataccatg cgagacccga ttctgatcag cgcttctgca cacagtatat
2281 catctatgaa gatttgtgta attatcaccc agagagggtt cggcagggca aagtctggaa
2341 ggctccttcg agctggttta tagactgtgt gatgtccttt gagttgcttc ctcttgacag
2401 ctgaatatta taccagatga acatttcaaa ttgaatttgc acggtttgtg agagcccag
//