LOCUS BC126275 4701 bp mRNA linear HUM 23-OCT-2006
DEFINITION Homo sapiens glutamyl-prolyl-tRNA synthetase, mRNA (cDNA clone
MGC:161553 IMAGE:8991991), complete cds.
ACCESSION BC126275
VERSION BC126275.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4701)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4701)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 7 Row: H Column: 5.
FEATURES Location/Qualifiers
source 1..4701
/db_xref="H-InvDB:HIT000388867"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:161553 IMAGE:8991991"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_313"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: GTTTGGCA"
gene 1..4701
/gene="EPRS"
/gene_synonym="EARS"
/gene_synonym="PARS"
/gene_synonym="PIG32"
/db_xref="GeneID:2058"
/db_xref="HGNC:HGNC:3418"
/db_xref="MIM:138295"
CDS 139..4677
/gene="EPRS"
/gene_synonym="EARS"
/gene_synonym="PARS"
/gene_synonym="PIG32"
/codon_start=1
/product="EPRS protein"
/protein_id="AAI26276.1"
/db_xref="GeneID:2058"
/db_xref="HGNC:HGNC:3418"
/db_xref="MIM:138295"
/translation="MATLSLTVNSGDPPLGALLAVEHVKDDVSISVEEGKENILHVSE
NVIFTDVNSILRYLARVATTAGLYGSNLMEHTEIDHWLEFSATKLSSCDSFTSTINEL
NHCLSLRTYLVGNSLSLADLCVWATLKGNAAWQEQLKQKKAPVHVKRWFGFLEAQQAF
QSVGTKWDVSTTKARVAPEKKQDVGKFVELPGAEMGKVTVRFPPEASGYLHIGHAKAA
LLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIKPDQFTYTSDHFETI
MKYAEKLIQEGKAYVDDTPAEQMKAEREQRIDSKHRKNPIEKNLQMWEEMKKGSQFGQ
SCCLRAKIDMSSNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTH
ALRTTEYHDRDEQFYWIIEALGIRKPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGW
DDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNMEWDKIWAFNKKVIDPVAPRYV
ALLKKEVIPVNVPEAQEEMKEVAKHPKNPEVGLKPVWYSPKVFIEGADAETFSEGEMV
TFINWGNLNITKIHKNADGKIISLDAKLNLENKDYKKTTKVTWLAETTHALPIPVICV
TYEHLITKPVLGKDEDFKQYVNKNSKHEELMLGDPCLKDLKKGDIIQLQRRGFFICDQ
PYEPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVEATKNETSAPFKERPTPSL
NNNCTTSEDSLVLYNRVAVQGDVVRELKAKKAPKEDVDAAVKQLLSLKAEYKEKTGQE
YKPGNPPAEIGQNISSNSSASILESKSLYDEVAAQGEVVRKLKAEKSPKAKINEAVEC
LLSLKAQYKEKTGKEYIPGQPPLSQSSDSSPTRNSEPAGLETPEAKVLFDKVASQGEV
VRKLKTEKAPKDQVDIAVQELLQLKAQYKSLIGVEYKPVSATGAEDKDKKKKEKENKS
EKQNKPQKQNDGQRKDPSKNQGGGLSSSGAGEGQGPKKQTRLGLEAKKEENLADWYSQ
VITKSEMIEYHDISGCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALE
KEKTHVADFAPEVAWVTRSGKTELAEPIAIRPTSETVMYPAYAKWVQSHRDLPIKLNQ
WCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQILDLYAQVYEELLAIP
VVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPKIP
GEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDK
EALIAKCNDYRRRLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQ
FVAVRRDTGEKLTVAENEAETKLQAILEDIQVTLFTRASEDLKTHMVVANTMEDFQKI
LDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGAKSLCIPFKPLCELQPGAK
CVCGKNPAKYYTLFGRSY"
BASE COUNT 1519 a 896 c 1121 g 1165 t
ORIGIN
1 ccaggcgtac tgacaggtgg ccaggcgtac tgacaggtgg ccaggcgtac tgacaggtgg
61 ccaggcgtac tgacaggtgg ccaggcgtac tgacaggtgg ccaggcgtac tgacaggtgg
121 accagcggac tggtggagat ggcgacgctc tctctgaccg tgaattcagg agaccctccg
181 ctaggagctt tgctggcagt agaacacgtg aaagacgatg tcagcatttc cgttgaagaa
241 gggaaagaga atattcttca tgtttctgaa aatgtgatat tcacagatgt gaattctata
301 cttcgctact tggctagagt tgcaactaca gctgggttat atggctctaa tctgatggaa
361 catactgaga ttgatcactg gttggagttc agtgctacaa aattatcttc atgtgattcc
421 tttacttcta caattaatga actcaatcat tgcctgtctc tgagaacata cttagttgga
481 aactccttga gtttagcaga tttatgtgtt tgggccaccc taaaaggaaa tgctgcctgg
541 caagaacagt tgaaacagaa gaaagctcca gttcatgtaa aacgttggtt tggctttctt
601 gaagcccagc aggccttcca gtcagtaggt accaagtggg atgtttcaac aaccaaagct
661 cgagtggcac ctgagaaaaa gcaagatgtt gggaaatttg ttgagcttcc aggtgcggag
721 atgggaaagg ttaccgtcag atttcctcca gaggccagtg gttacttaca cattgggcat
781 gcaaaagctg ctcttctgaa ccagcactac caggttaact ttaaagggaa actgatcatg
841 agatttgatg acacaaatcc tgaaaaagaa aaggaagatt ttgagaaggt tatcttggaa
901 gatgttgcaa tgttgcatat caaaccagat caatttactt atacttcgga tcattttgaa
961 actataatga agtatgcaga gaagctaatt caagaaggga aggcttatgt ggatgatact
1021 cctgctgaac agatgaaagc agaacgtgag cagaggatag actctaaaca tagaaaaaac
1081 cctattgaga agaatctaca aatgtgggaa gaaatgaaaa aagggagcca gtttggtcag
1141 tcctgttgtt tgcgagcaaa aattgacatg agtagtaaca atggatgcat gagagatcca
1201 accctttatc gctgcaaaat tcaaccacat ccaagaactg gaaataaata caatgtttat
1261 ccaacatatg attttgcctg ccccatagtt gacagcatcg aaggtgttac acatgccctg
1321 agaacaacag aataccatga cagagatgag cagttttact ggattattga agctttaggc
1381 ataagaaaac catatatttg ggaatatagt cggctaaatc tcaacaacac agtgctatcc
1441 aaaagaaaac tcacatggtt tgtcaatgaa ggactagtag atggatggga tgacccaaga
1501 tttcctacgg ttcgtggtgt actgagaaga gggatgacag ttgaaggact gaaacagttt
1561 attgctgctc agggctcctc acgttcagtc gtgaacatgg agtgggacaa aatctgggcg
1621 tttaacaaaa aggttattga cccagtggct ccacgatatg ttgcattact gaagaaagaa
1681 gtgatcccag tgaatgtacc tgaagctcag gaggagatga aagaagtagc caaacaccca
1741 aagaatcctg aggttggctt gaagcctgtg tggtatagtc ccaaagtttt cattgaaggt
1801 gctgatgcag agactttttc ggagggtgag atggttacat ttataaattg gggcaacctc
1861 aacattacaa aaatacacaa aaatgcagat ggaaaaatca tatctcttga tgcaaagttg
1921 aatttggaaa acaaagacta caagaaaacc actaaggtca cttggcttgc agagactaca
1981 catgctcttc ctattccagt aatctgtgtc acttatgagc acttgatcac aaagccagtg
2041 ctaggaaaag acgaggactt taagcagtat gtcaacaaga acagtaagca tgaagagcta
2101 atgctagggg atccctgcct taaggatttg aaaaaaggag atattataca actccagaga
2161 agaggattct tcatatgtga tcaaccttat gaacctgtta gcccatatag ttgcaaggaa
2221 gccccgtgtg ttttgatata cattcctgat gggcacacaa aggaaatgcc aacatcaggg
2281 tcaaaggaaa agaccaaagt agaagccaca aaaaatgaga cctctgctcc ttttaaggaa
2341 agaccaacac cttctctgaa taataattgt actacatctg aggattcctt ggtcctttac
2401 aatagagtgg ctgttcaagg agatgtggtt cgtgaattaa aagccaagaa agcaccaaag
2461 gaagatgtag atgcagctgt aaaacagctt ttgtctttga aagctgaata taaggagaaa
2521 actggccagg aatataaacc tggaaaccct cctgctgaaa taggacagaa tatttcttct
2581 aattcctcag caagtattct ggaaagtaaa tctctgtatg atgaagttgc tgcacaaggg
2641 gaggtggttc gtaagctaaa agctgaaaaa tcccctaagg ctaaaataaa tgaagctgta
2701 gaatgcttac tgtccctgaa ggctcagtat aaagaaaaaa ctgggaagga gtacatacct
2761 ggtcagcccc cattatctca aagttcggat tcaagcccaa ccagaaattc tgaacctgct
2821 ggtttagaaa caccagaagc gaaagtactt tttgacaaag tagcttctca aggggaagta
2881 gttcggaaac ttaaaactga aaaagcccct aaggatcaag tagatatagc tgttcaagaa
2941 ctccttcagc taaaggcaca gtacaagtct ttgataggag tagagtataa gcctgtgtcg
3001 gccactggag ctgaggacaa agataagaag aagaaagaaa aagaaaataa atctgaaaag
3061 cagaataagc ctcagaaaca aaatgatggc caaaggaaag acccttctaa aaaccaagga
3121 ggtgggctct catcaagtgg agcaggagaa gggcaggggc ctaagaaaca gaccaggttg
3181 ggtcttgagg caaaaaaaga agaaaatctt gctgattggt attctcaggt catcacaaag
3241 tcagaaatga ttgaatacca tgacataagt ggctgttata ttcttcgtcc ctgggcctat
3301 gccatttggg aagccatcaa ggactttttt gatgctgaga tcaagaaact tggtgttgaa
3361 aactgctact tccccatgtt tgtgtctcaa agtgcattag agaaagagaa gactcatgtt
3421 gctgactttg ccccagaggt tgcttgggtt acaagatctg gcaaaaccga gctggcagaa
3481 ccaattgcca ttcgtcctac tagtgaaaca gtaatgtatc ctgcatatgc aaaatgggta
3541 cagtcacaca gagacctgcc catcaagctc aatcagtggt gcaatgtggt gcgttgggaa
3601 ttcaagcatc ctcagccttt cctacgtact cgtgaatttc tttggcagga agggcacagt
3661 gcttttgcta ccatggaaga ggcagcggaa gaggtcttgc agatacttga cttatatgct
3721 caggtatatg aagaactcct ggcaattcct gttgttaaag gaagaaagac ggaaaaggaa
3781 aaatttgcag gaggagacta tacaactaca atagaagcat ttatatctgc tagtggaaga
3841 gctatccagg gaggaacatc acatcattta gggcagaatt tttccaaaat gtttgaaatc
3901 gtttttgaag atccaaagat accaggagag aagcaatttg cctatcaaaa ctcctggggc
3961 ctgacaactc gaactattgg tgttatgacc atggttcatg gggacaacat gggtttagta
4021 ttaccacccc gtgtagcatg tgttcaggtg gtgattattc cttgtggcat taccaatgca
4081 ctttctgaag aagacaaaga agcgctgatt gcaaaatgca atgattatcg aaggcgatta
4141 ctcagtgtta acatccgcgt tagagctgat ttacgagata attattctcc aggttggaaa
4201 ttcaatcact gggagctcaa gggagttccc attagacttg aagttgggcc acgtgatatg
4261 aagagctgtc agtttgtagc cgtcagacga gatactggag aaaagctgac agttgctgaa
4321 aatgaggcag agactaaact tcaagctatt ttggaagaca tccaggtcac ccttttcaca
4381 agggcttctg aagaccttaa gactcatatg gttgtggcta atacaatgga agactttcag
4441 aagatactag attctggaaa gattgttcag attccattct gtggggaaat tgactgtgag
4501 gactggatca aaaagaccac tgccagggat caagatcttg aacctggtgc tccatccatg
4561 ggagctaaaa gcctttgcat ccccttcaaa ccactctgtg aactgcagcc tggagccaaa
4621 tgtgtctgtg gcaagaaccc tgccaagtac tacaccttat ttggtcgcag ctactgaggg
4681 atgaacgaaa gccccctctt c
//