LOCUS BC126201 5147 bp mRNA linear HUM 23-OCT-2006
DEFINITION Homo sapiens protein tyrosine phosphatase, receptor type, O, mRNA
(cDNA clone MGC:161479 IMAGE:8991917), complete cds.
ACCESSION BC126201
VERSION BC126201.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5147)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5147)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 7 Row: E Column: 3.
FEATURES Location/Qualifiers
source 1..5147
/db_xref="H-InvDB:HIT000388793"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:161479 IMAGE:8991917"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_312"
/note="Vector: pCR-XL-TOPO; Clone identification sequence
tag: TGGGTTGA"
gene 1..5147
/gene="PTPRO"
/gene_synonym="GLEPP1"
/gene_synonym="PTP-U2"
/gene_synonym="PTPU2"
/db_xref="GeneID:5800"
/db_xref="HGNC:HGNC:9678"
/db_xref="MIM:600579"
CDS 171..3821
/gene="PTPRO"
/gene_synonym="GLEPP1"
/gene_synonym="PTP-U2"
/gene_synonym="PTPU2"
/codon_start=1
/product="protein tyrosine phosphatase, receptor type, O"
/protein_id="AAI26202.1"
/db_xref="GeneID:5800"
/db_xref="HGNC:HGNC:9678"
/db_xref="MIM:600579"
/translation="MGHLPTGIHGARRLLPLLWLFVLFKNATAFHVTVQDDNNIVVSL
EASDVISPASVYVVKITGESKNYFFEFEEFNSTLPPPVIFKASYHGLYYIITLVVVNG
NVVTKPSRSITVLTKPLPVTSVSIYDYKPSPETGVLFEIHYPEKYNVFTRVNISYWEG
KDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQH
RTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPS
GNISSGWPDFNSSDYETTSQPYWWDSASAAPESEDEFVSVLPMEYENNSTLSETEKST
SGSFSFFPVQMILTWLPPKPPTAFDGFHIHIEREENFTEYLMVDEEAHEFVAELKEPG
KYKLSVTTFSSSGSCETRKSQSAKSLSFYISPSGEWIEELTEKPQHVSVHVLSSTTAL
MSWTSSQENYNSTIVSVVSLTCQKQKESQRLEKQYCTQVNSSKPIIENLVPGAQYQVV
IYLRKGPLIGPPSDPVTFAIVPTGIKDLMLYPLGPTAVVLSWTRPYLGVFRKYVVEMF
YFNPATMTSEWTTYYEIAATVSLTASVRIANLLPAWYYNFRVTMVTWGDPELSCCDSS
TISFITAPVAPEITSVEYFNSLLYISWTYGDDTTDLSHSRMLHWMVVAEGKKKIKKSV
TRNVMTAILSLPPGDIYNLSVTACTERGSNTSMLRLVKLEPAPPKSLFAVNKTQTSVT
LLWVEEGVADFFEVFCQQVGSSQKTKLQEPVAVSSHVVTISSLLPATAYNCSVTSFSH
DSPSVPTFIAVSTMVTEMNPNVVVISVLAILSTLLIGLLLVTLIILRKKHLQMARECG
AGTFVNFASLERDGKLPYNWRRSIFAFLTLLPSCLWTDYLLAFYINPWSKNGLKKRKL
TNPVQLDDFDAYIKDMAKDSDYKFSLQFEELKLIGLDIPHFAADLPLNRCKNRYTNIL
PYDFSRVRLVSMNEEEGADYINANYIPGYNSPQEYIATQGPLPETRNDFWKMVLQQKS
QIIVMLTQCNEKRRVKCDHYWPFTEEPIAYGDITVEMISEEEQDDWACRHFRINYADE
MQDVMHFNYTAWPDHGVPTANAAESILQFVHMVRQQATKSKGPMIIHCSAGVGRTGTF
IALDRLLQHIRDHEFVDILGLVSEMRSYRMSMVQTEEQYIFIHQCVQLMWMKKKQQFC
ISDVIYENVSKS"
BASE COUNT 1440 a 1115 c 1141 g 1451 t
ORIGIN
1 gcagaggagg aaagggagca ggcgcagggg gactggaaag gcagcatgcg ctcgccagga
61 gcaacctcgg cgcccagggt ctgaggctgc agccccagtt cgccattgtg agccgccgcc
121 gggggagtcc gctagcgcag ccgtgccccc gagtccccgt ccgcgcagcg atggggcacc
181 tgcccacggg gatacacggc gcccgccgcc tcctgcctct gctctggctc tttgtgctgt
241 tcaagaatgc tacagctttc catgtaactg tccaagatga taataacatc gttgtctcat
301 tagaagcttc agacgtcatc agtccagcat ctgtgtatgt tgtgaagata actggtgaat
361 ccaaaaatta tttcttcgaa tttgaggaat tcaacagcac tttgcctcct cctgttattt
421 tcaaggccag ttatcatggc ctttattata taatcactct ggtagtggta aatggaaatg
481 tggtgaccaa gccatccaga tcaatcactg tgttaacaaa acctctacct gtaaccagtg
541 tttccatata tgactataaa ccttctcctg aaacaggagt cctgtttgaa atacattatc
601 cagaaaaata taacgttttc acaagagtga acattagcta ctgggaaggt aaagacttcc
661 ggacaatgct atataaagat ttctttaagg gaaaaacagt atttaatcac tggctgccag
721 gaatgtgtta tagtaatatc acctttcagc tggtatctga ggcaactttt aataaaagta
781 cccttgttga gtacagtggt gtcagtcacg aacccaaaca gcacagaact gccccttatc
841 cacctcaaaa tatttccgtt cgtatcgtaa acttgaacaa aaacaactgg gaagaacaga
901 gtggcaattt cccagaagaa tccttcatga gatcacaaga tacaatagga aaagaaaaac
961 tcttccattt tacagaagaa acccctgaaa ttccctcggg caacatttct tccggttggc
1021 ctgattttaa tagcagtgac tatgaaacta cgtctcagcc atattggtgg gacagtgcat
1081 ctgcagctcc tgaaagtgaa gatgaatttg tcagcgtact tcccatggaa tacgaaaata
1141 acagtacact cagtgagaca gagaagtcaa catcaggctc tttctccttt ttccctgtgc
1201 aaatgatatt gacctggtta ccacccaaac cacccactgc ttttgatggg ttccatatcc
1261 atattgaacg agaagagaac tttactgaat atttgatggt ggatgaagaa gcacatgaat
1321 ttgttgcaga actgaaggaa cctgggaaat ataagttatc tgtgacaacc tttagttcct
1381 caggatcttg tgaaactcga aaaagtcagt cagcaaaatc actcagcttt tatatcagtc
1441 cttcaggaga gtggattgaa gaactgaccg agaagccgca gcacgtgagt gtccacgttt
1501 taagctcaac cactgccttg atgtcctgga catcttccca agagaactac aacagcacca
1561 ttgtgtctgt ggtgtcgctg acctgccaga aacaaaagga gagccagagg cttgaaaagc
1621 agtactgcac tcaggtgaac tcaagcaaac ctattattga aaatctggtt cctggtgccc
1681 agtaccaggt tgtaatatac ctaaggaaag gccctttgat tggaccacct tcagatcctg
1741 tgacatttgc tattgttccc acaggaataa aggatttaat gctctatcct ttgggtccta
1801 cggccgtggt tctgagctgg accagacctt atttaggcgt gttcagaaaa tacgtggttg
1861 aaatgtttta tttcaaccct gctacaatga catcagagtg gaccacctac tatgaaatag
1921 cagcaactgt ttccttaact gcatccgtga gaatagctaa tctgctgcca gcatggtact
1981 acaacttccg ggttaccatg gtgacgtggg gagatccaga attgagctgc tgtgacagct
2041 ctaccatcag cttcataaca gccccagtgg ctccggaaat cacttctgtg gaatatttca
2101 acagtctgtt atatatcagt tggacatatg gggatgatac aacggacttg tcccattcta
2161 gaatgcttca ctggatggtg gttgcagaag gaaaaaagaa aattaaaaag agtgtaacac
2221 gcaatgtcat gactgcaatt ctcagcttgc ctccaggcga catctataac ctctcagtaa
2281 ctgcttgtac tgaaagagga agtaatacct ccatgctccg ccttgtcaag ctagaaccag
2341 ctccacccaa atcactcttc gcagtgaaca aaacccagac ttcagtgact ttgctgtggg
2401 tggaagaggg agtagctgat ttctttgaag ttttctgtca acaagttggc tccagtcaga
2461 aaaccaaact tcaggaacca gttgctgttt cttcccatgt cgtgaccatc tccagccttc
2521 ttcctgccac tgcctacaat tgtagtgtca ccagctttag ccatgacagc cccagtgtcc
2581 ctacgttcat agccgtctca acaatggtta cagagatgaa tcccaatgtg gtagtgatct
2641 ccgtgctggc catccttagc acacttttaa ttggactgtt gcttgttacc ctcattattc
2701 ttaggaaaaa gcatctgcag atggctaggg agtgtggagc tggtacattt gtcaattttg
2761 catccttaga gagggatgga aagcttccat acaactggcg taggagtata tttgctttct
2821 taaccctgct accctcatgt ctttggactg attatctttt ggcattttat attaatcctt
2881 ggagtaaaaa tggtttaaag aagaggaaac tgacaaaccc ggttcaactg gatgactttg
2941 atgcctatat taaggatatg gccaaagact ctgactataa attttctctt cagtttgagg
3001 agttgaaatt gattggactg gatatcccac actttgctgc agatcttcca ctgaatcgat
3061 gtaaaaaccg ttacacaaac atcctaccat atgacttcag ccgtgtgaga ttagtctcca
3121 tgaatgaaga ggaaggtgca gactacatca atgccaacta tattcctgga tacaactcac
3181 cccaggagta tattgccacc caggggccac tgcctgaaac cagaaatgac ttctggaaga
3241 tggtcctgca acaaaagtct cagattattg tcatgctcac tcagtgtaat gagaaaagga
3301 gggtgaaatg tgaccattac tggccattca cggaagaacc tatagcctat ggagacatca
3361 ctgtggagat gatttcagag gaagagcagg acgactgggc ctgtagacac ttccggatca
3421 actatgctga cgagatgcag gatgtgatgc attttaacta cactgcatgg cctgatcatg
3481 gtgtgcccac agcaaatgct gcagaaagta tcctgcagtt tgtacacatg gtccgacagc
3541 aagctaccaa gagcaaaggt cccatgatca ttcactgcag tgctggcgtg ggacggacag
3601 gaacattcat tgccctggac aggctcttgc agcacattcg ggatcatgag tttgttgaca
3661 tcttagggct ggtgtcagaa atgaggtcat accggatgtc tatggtacag acagaggagc
3721 agtacatttt tatccatcag tgtgtgcaac tgatgtggat gaagaagaag cagcagttct
3781 gcatcagtga tgtcatatac gagaatgtta gcaagtccta gttcagaatc cggagcagag
3841 aggacatgat gtgcgcccat cctcccttgc ttccagattg ttttagtggg ccctgatggt
3901 catttttcta aacagaggcc ctgctttgta atatgtggcc aaggagataa tttatctcac
3961 agaagcaccg ggaagactta gccttaaaga gcctacagtg tccttttgga ctctttcact
4021 tcgggacatt taataatgga ccaaattcaa cagaacacca ggaaggtcaa gacgctctcc
4081 aaagggcagg aagtacagca cttccgaaga gtttagttgg ccctttgctg gttgggctga
4141 gttttttatt tttaagtgtt tgtttttcag tgcaataatt tttgtgtgtg tgtgattctt
4201 atcagaaagt tgaattgttt tctgcctaca ccgttcatca gccccataac ccaggaagga
4261 acaggcattg ttagcatcag attatacctc attattaaaa ggaggcatgg ccacacatga
4321 agaaatggtc attctacttc aaagaaattg agccagcact atctgtactc caacattacc
4381 ggatctggat tggggaggtt ggtcagggaa gagaggggtt ctacccacag atcaactgtg
4441 taatctttta ctattcaagc tataattcag cttcaaagta gagtagaaaa aaaattgtct
4501 taactgttct agttcttgat ggttttcttc cttattaaca gttggtgttt cttccttggc
4561 ccttttggac taatgttact gtccaagttc tttctcaaga aaccacatct ggttcagaag
4621 agtgtcaagt tggactcttt gaactctgtt gctgtctgag caatcgtggt gcctagactt
4681 tgcattcctt gttctgttga cctgcataca tgtgagagct atttctttaa gaactatata
4741 ggctgtgaaa acgcactttc tttcccccaa agagctggga atttatgaag ttatggcaat
4801 gaactgcagc atgctgggac aattatttga ctactttttt ttgtaatatt gtcaaatgtc
4861 tctatggatt ctgacagaga tttctttttg ttttgttatt cttttggttg tcagtttcat
4921 tttaacgagt gtaactagta acattttatt ctttggattt tgtataatta cagtacatga
4981 ttgtgtattg tgacatgaat gctgtcaaaa tgacattgat ggcattgtga agcctgttac
5041 tttgtgtcac ttcctgataa ataagaggtg atgacatgga tatacaacag aaaacacttt
5101 gagttgaaag taaacacaag ctggctgctt ccctgtggca actgtgg
//