LOCUS BC126199 2764 bp mRNA linear HUM 23-OCT-2006
DEFINITION Homo sapiens plakophilin 2, mRNA (cDNA clone MGC:161477
IMAGE:8991915), complete cds.
ACCESSION BC126199
VERSION BC126199.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2764)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2764)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 7 Row: E Column: 1.
FEATURES Location/Qualifiers
source 1..2764
/db_xref="H-InvDB:HIT000388791"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:161477 IMAGE:8991915"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: TGAAGGTT"
gene 1..2764
/gene="PKP2"
/gene_synonym="ARVD9"
/db_xref="GeneID:5318"
/db_xref="HGNC:HGNC:9024"
/db_xref="MIM:602861"
CDS 45..2558
/gene="PKP2"
/gene_synonym="ARVD9"
/codon_start=1
/product="plakophilin 2"
/protein_id="AAI26200.1"
/db_xref="GeneID:5318"
/db_xref="HGNC:HGNC:9024"
/db_xref="MIM:602861"
/translation="MAAPGAPAEYGYIRTVLGQQILGQLDSSSLALPSEAKLKLAGSS
GRGGQTVKSLRIQEQVQQTLARKGRSSVGNGNLHRTSSVPEYVYNLHLVENDFVGGRS
PVPKTYDMLKAGTTATYEGRWGRGTAQYSSQKSVEERSLRHPLRRLEISPDSSPERAH
YTHSDYQYSQRSQAGHTLHHQESRRAALLVPPRYARSEIVGVSRAGTTSRQRHFDTYH
RQYQHGSVSDTVFDSIPANPALLTYPRPGTSRSMGNLLEKENYLTAGLTVGQVRPLVP
LQPVTQNRASRSSWHQSSFHSTRTLREAGPSVAVDSSGRRAHLTVGQAAAGGSGNLLT
ERSTFTDSQLGNADMEMTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVN
QLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTR
DLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDF
DIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCI
LHNLSYQLEAELPEKYSQNIYIQNRNIQTDNNKSIGCFGSRSRKVKEQYQDVPMPEEK
SNPKGVEWLWHSIVIRMYLSLIAKSVRNYTQEASLGALQNLTAGSGPMPTSVAQTVVQ
KESGLQHTRKMLHVGDPSVKKTAISLLRNLSRNLSLQNEIAKETLPDLVSIIPDTVPS
TDLLIETTASACYTLNNIIQNSYQNARDLLNTGGIQKIMAISAGDAYASNKASKAASV
LLYSLWAHTELHHAYKKAQFKKTDFVNSRTAKAYHSLKD"
BASE COUNT 749 a 753 c 708 g 554 t
ORIGIN
1 gagtccagag gcaggcgagc agctcggtcg cccccaccgg ccccatggca gcccccggcg
61 ccccagctga gtacggctac atccggaccg tcctgggcca gcagatcctg ggacaactgg
121 acagctccag cctggcgctg ccctccgagg ccaagctgaa gctggcgggg agcagcggcc
181 gcggcggcca gacagtcaag agcctgcgga tccaggagca ggtgcagcag accctcgccc
241 ggaagggccg cagctccgtg ggcaacggaa atcttcaccg aaccagcagt gttcctgagt
301 atgtctacaa cctacacttg gttgaaaatg attttgttgg aggccgttcc cctgttccta
361 aaacctatga catgctaaag gctggcacaa ctgccactta tgaaggtcgc tggggaagag
421 gaacagcaca gtacagctcc cagaagtccg tggaagaaag gtccttgagg catcctctga
481 ggagactgga gatttctcct gacagcagcc cggagagggc tcactacacg cacagcgatt
541 accagtacag ccagagaagc caggctgggc acaccctgca ccaccaagaa agcaggcggg
601 ccgccctcct agtgccaccg agatatgctc gttccgagat cgtgggggtc agccgtgctg
661 gcaccacaag caggcagcgc cactttgaca cataccacag acagtaccag catggctctg
721 ttagcgacac cgtttttgac agcatccctg ccaacccggc cctgctcacg taccccaggc
781 cagggaccag ccgcagcatg ggcaacctct tggagaagga gaactacctg acggcagggc
841 tcactgtcgg gcaggtcagg ccgctggtgc ccctgcagcc cgtcactcag aacagggctt
901 ccaggtcctc ctggcatcag agctccttcc acagcacccg cacgctgagg gaagctgggc
961 ccagtgtcgc cgtggattcc agcgggagga gagcgcactt gactgtcggc caggcggccg
1021 cagggggaag tgggaatctg ctcactgaga gaagcacttt cactgactcc cagctgggga
1081 atgcagacat ggagatgact ctggagcgag cagtgagtat gctcgaggca gaccacatgc
1141 tgccatccag gatttctgct gcagctactt tcatacagca cgagtgcttc cagaaatctg
1201 aagctcggaa gagggttaac cagcttcgtg gcatcctcaa gcttctgcag ctcctaaaag
1261 ttcagaatga agacgttcag cgagctgtgt gtggggcctt gagaaactta gtatttgaag
1321 acaatgacaa caaattggag gtggctgaac taaatggggt acctcggctg ctccaggtgc
1381 tgaagcaaac cagagacttg gagactaaaa aacaaataac aggtttgctg tggaatttgt
1441 catctaatga caaactcaag aatctcatga taacagaagc attgcttacg ctgacggaga
1501 atatcatcat ccccttttct gggtggcctg aaggagacta cccaaaagca aatggtttgc
1561 tcgattttga catattctac aacgtcactg gatgcctaag aaacatgagt tctgctggcg
1621 ctgatgggag aaaagcgatg agaagatgtg acggactcat tgactcactg gtccattatg
1681 tcagaggaac cattgcagat taccagccag atgacaaggc cacggagaat tgtgtgtgca
1741 ttcttcataa cctctcctac cagctggagg cagagctccc agagaaatat tcccagaata
1801 tctatattca aaaccggaat atccagactg acaacaacaa aagtattgga tgttttggca
1861 gtcgaagcag gaaagtaaaa gagcaatacc aggacgtgcc gatgccggag gaaaagagca
1921 accccaaggg cgtggagtgg ctgtggcatt ccattgttat aaggatgtat ctgtccttga
1981 tcgccaaaag tgtccgcaac tacacacaag aagcatcctt aggagctctg cagaacctca
2041 cggccggaag tggaccaatg ccgacatcag tggctcagac agttgtccag aaggaaagtg
2101 gcctgcagca cacccgaaag atgctgcatg ttggtgaccc aagtgtgaaa aagacagcca
2161 tctcgctgct gaggaatctg tcccggaatc tttctctgca gaatgaaatt gccaaagaaa
2221 ctctccctga tttggtttcc atcattcctg acacagtccc gagtactgac cttctcattg
2281 aaactacagc ctctgcctgt tacacattga acaacataat ccaaaacagt taccagaatg
2341 cacgcgacct tctaaacacc gggggcatcc agaaaattat ggccattagt gcaggcgatg
2401 cctatgcctc caacaaagca agtaaagctg cttccgtcct tctgtattct ctgtgggcac
2461 acacggaact gcatcatgcc tacaagaagg ctcagtttaa gaagacagat tttgtcaaca
2521 gccggactgc caaagcctac cactccctta aagactgagg aaaatgacaa agtattctcg
2581 gctgcaaaaa tccccaaagg aaaacaccta tttttctact acccagccca agaaacctca
2641 aaagcatgcc ttgtttctat ccttctctat ttccgtggtc ccctgaatcc agaaaacaaa
2701 tagaacataa ttttatgagt cttccagaag acctttgcaa gtttgccacc agtagatacc
2761 ggcc
//