LOCUS BC126121 3235 bp mRNA linear HUM 23-OCT-2006
DEFINITION Homo sapiens connector enhancer of kinase suppressor of Ras 2, mRNA
(cDNA clone MGC:161399 IMAGE:8991837), complete cds.
ACCESSION BC126121
VERSION BC126121.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3235)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3235)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (22-OCT-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 7 Row: A Column: 19.
FEATURES Location/Qualifiers
source 1..3235
/db_xref="H-InvDB:HIT000388713"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:161399 IMAGE:8991837"
/tissue_type="Brain, cerebellum, PCR rescued clones"
/clone_lib="NIH_MGC_311"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: CCTCTAAT"
gene 1..3235
/gene="CNKSR2"
/gene_synonym="CNK2"
/gene_synonym="KIAA0902"
/gene_synonym="KSR2"
/db_xref="GeneID:22866"
/db_xref="HGNC:HGNC:19701"
CDS 36..3140
/gene="CNKSR2"
/gene_synonym="CNK2"
/gene_synonym="KIAA0902"
/gene_synonym="KSR2"
/codon_start=1
/product="connector enhancer of kinase suppressor of Ras
2"
/protein_id="AAI26122.1"
/db_xref="GeneID:22866"
/db_xref="HGNC:HGNC:19701"
/translation="MALIMEPVSKWSPSQVVDWMKGLDDCLQQYIKNFEREKISGDQL
LRITHQELEDLGVSRIGHQELILEAVDLLCALNYGLETENLKTLSHKLNASAKNLQNF
ITGRRRSGHYDGRTSRKLPNDFLTSVVDLIGAAKSLLAWLDRSPFAAVTDYSVTRNNV
IQLCLELTTIVQQDCTVYETENKILHVCKTLSGVCDHIISLSSDPLVSQSAHLEVIQL
ANIKPSEGLGMYIKSTYDGLHVITGTTENSPADRCKKIHAGDEVIQVNHQTVVGWQLK
NLVNALREDPSGVILTLKKRPQSMLTSAPALLKNMRWKPLALQPLIPRSPTSSVATPS
STISTPTKRDSSALQDLYIPPPPAEPYIPRDEKGNLPCEDLRGHMVGKPVHKGSESPN
SFLDQEYRKRFNIVEEDTVLYCYEYEKGRSSSQGRRESTPTYGKLRPISMPVEYNWVG
DYEDPNKMKRDSRRENSLLRYMSNEKIAQEEYMFQRNSKKDTGKKSKKKGDKSNSPTH
YSLLPSLQMDALRQDIMGTPVPETTLYHTFQQSSLQHKSKKKNKGPIAGKSKRRISCK
DLGRGDCEGWLWKKKDAKSYFSQKWKKYWFVLKDASLYWYINEEDEKAEGFISLPEFK
IDRASECRKKYAFKACHPKIKSFYFAAEHLDDMNRWLNRINMLTAGYAERERIKQEQD
YWSESDKEEADTPSTPKQDSPPPPYDTYPRPPSMSCASPYVEAKHSRLSSTETSQSQS
SHEEFRQEVTGSSAVSPIRKTASQRRSWQDLIETPLTSSGLHYLQTLPLEDSVFSDSA
AISPEHRRQSTLPTQKCHLQDHYGPYPLAESERMQVLNGNGGKPRSFTLPRDSGFNHC
CLNAPVSACDPQDDVQPPEVEEEEEEEEEEGEAAGENIGEKSESREEKLGDSLQDLYR
ALEQASLSPLGEHRISTKMEYKLSFIKRCNDPVMNEKLHRLRILKSTLKAREGEVAII
DKVLDNPDLTSKEFQQWKQMYLDLFLDICQNTTSNDPLSISSEVDVITSSLAHTHSYI
ETHV"
BASE COUNT 1039 a 690 c 748 g 758 t
ORIGIN
1 agctctgcgc tctgcacgga accgaccccg tacccatggc tctgataatg gaaccggtga
61 gcaaatggtc tccgagtcaa gtagtggact ggatgaaagg tcttgatgac tgtttgcagc
121 agtatattaa gaactttgag agggagaaga tcagtgggga ccagctgctg cgcattacac
181 atcaggagct agaagatctg ggggtcagcc gcattggcca tcaggaactg atcttggaag
241 cagttgacct tctgtgtgca ttgaattatg gcttggaaac agaaaatcta aaaacccttt
301 ctcacaagtt gaatgcatct gccaaaaatc tgcagaattt tataacagga aggagaagga
361 gtggccatta tgatgggagg accagccgaa aattgccaaa cgactttctg acctcagttg
421 tggatctgat tggagcagcc aagagtctgc ttgcctggtt ggacaggtca ccatttgctg
481 ctgtgacaga ctattcagtt acaagaaata atgtcataca actctgcctg gagttaacaa
541 caattgtgca acaggattgt actgtatatg aaacagagaa taaaattctt cacgtgtgta
601 aaactctttc tggagtctgt gaccacatca tatccctgtc gtcagatcct ctggtttcac
661 agtctgctca cctggaagtg attcaactgg caaacattaa accaagcgaa gggctgggta
721 tgtatattaa atctacatat gatggcctcc atgtaattac tggaaccaca gaaaattcac
781 ctgcagatcg gtgcaagaaa atccatgctg gcgatgaagt gattcaagtt aatcatcaga
841 ctgtggtggg gtggcagttg aaaaatttgg tgaatgcact acgagaggac ccgagtggtg
901 ttatcttaac tttgaaaaag cgacctcaga gcatgcttac ctcagcacca gctttactga
961 aaaatatgag atggaagccc cttgctctgc agcctcttat acctagaagt cccacaagca
1021 gcgttgccac gccttccagc accatcagta cacccaccaa aagagacagt tctgccctcc
1081 aggatctcta cattccccct cctcctgcag aaccatatat tcccagggat gaaaaaggaa
1141 accttccttg tgaagacctc agaggacata tggtgggcaa gccagtgcat aagggatctg
1201 aatcaccaaa ttcatttctg gatcaggaat atcgaaagag atttaatatt gtcgaagaag
1261 atactgtctt atattgctat gaatatgaaa aaggaagatc aagtagtcaa ggaagacgag
1321 aaagcacccc aacttatggc aagctacgac ctatatctat gccagtggaa tataattggg
1381 tgggggacta tgaagatcca aataagatga agagagatag tagaagagaa aactctctac
1441 ttcggtatat gagcaatgaa aagattgctc aagaagaata catgtttcag agaaacagca
1501 aaaaggacac agggaagaag tcaaaaaaga agggtgataa gagtaatagc ccaactcact
1561 attcattgct acctagttta caaatggatg cactgagaca agacatcatg ggcactcctg
1621 tgccagagac cacactatac catacatttc agcagtcctc actgcagcac aaatcaaaga
1681 agaaaaacaa aggtcctata gcaggcaaga gcaaaagacg aatttcttgc aaagatcttg
1741 gccgtggtga ctgtgagggc tggctttgga aaaagaaaga tgcgaagagt tacttttcac
1801 agaaatggaa aaaatattgg tttgtcctaa aggatgcatc cctttattgg tatattaatg
1861 aggaggatga aaaagcagaa ggattcatta gcctgcctga atttaaaatt gatagagcca
1921 gtgaatgccg caaaaaatat gcattcaaag cctgtcatcc taaaatcaaa agcttttatt
1981 ttgctgctga acatcttgat gatatgaaca ggtggcttaa cagaattaat atgctgactg
2041 caggatatgc agaaagagag aggattaagc aggaacaaga ttactggagt gagagtgaca
2101 aggaagaagc agatactcca tcaacaccaa aacaagatag ccctccaccc ccatatgata
2161 catacccacg acctccctcg atgagttgcg ccagtcctta tgtggaagca aaacatagcc
2221 gactttcctc cacggagact tctcagtctc agtcttctca tgaggagttt cgccaggaag
2281 taactgggag cagtgcagtg tctcccattc gcaagacagc cagtcagcgc cgctcctggc
2341 aggatttaat tgagacgcca ctgacaagtt caggcttaca ctatcttcag actctgcccc
2401 tggaggattc tgtcttctct gactccgcgg ccatctcccc agagcacagg cggcagtcta
2461 ccctgccaac tcagaaatgc cacctgcagg atcactatgg gccatacccc ttagctgaga
2521 gtgagaggat gcaagtgcta aatggaaatg ggggcaagcc tcgaagtttt actctgcctc
2581 gagatagcgg gttcaaccat tgctgtctga atgctccagt tagtgcctgt gacccacagg
2641 atgacgtgca acccccagag gtggaggaag aggaggagga ggaggaggag gaaggggagg
2701 cagcagggga aaacatagga gaaaaaagtg aaagcagaga agaaaagtta ggagactcat
2761 tgcaagattt atacagggca ctggagcagg ccagtctgtc accactagga gaacatcgta
2821 tttcaaccaa gatggaatac aagctatcat ttataaaaag atgtaatgat cctgtaatga
2881 atgaaaaact acaccggctg agaattctca aaagcacttt aaaggccaga gaaggggaag
2941 tagccattat cgataaagtc ctagacaatc cagacttgac atctaaagaa ttccaacaat
3001 ggaagcagat gtacctcgac cttttcttgg atatctgtca aaataccacc tcaaatgacc
3061 cactgagtat ttcttctgaa gtagatgtaa tcacttcctc tctagcacac actcattcat
3121 acattgaaac gcatgtctaa atgtattctg ccttcagacc atctagtacc tgctggtact
3181 ctgaacaagt atataaggta gtttttatat caatgtgtgg aacacttgac aagct
//