LOCUS BC121046 1886 bp mRNA linear HUM 04-OCT-2006
DEFINITION Homo sapiens ADAM metallopeptidase domain 18, mRNA (cDNA clone
IMAGE:40117921), complete cds.
ACCESSION BC121046
VERSION BC121046.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1886)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1886)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (02-AUG-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 27 Row: k Column: 12
This clone has the following problem: The cds is short compared to
the longest cds in the locus.
FEATURES Location/Qualifiers
source 1..1886
/db_xref="H-InvDB:HIT000388243"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40117921"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: AATATATT sequenced from the reverse primer"
gene 1..1886
/gene="ADAM18"
/gene_synonym="ADAM27"
/gene_synonym="tMDCIII"
/db_xref="GeneID:8749"
/db_xref="HGNC:HGNC:196"
CDS 1397..1858
/gene="ADAM18"
/gene_synonym="ADAM27"
/gene_synonym="tMDCIII"
/codon_start=1
/product="ADAM18 protein"
/protein_id="AAI21047.1"
/db_xref="GeneID:8749"
/db_xref="HGNC:HGNC:196"
/translation="MRSDGTDNAYVADGTMCGPEMYCVNKTCRKVHLMGYNCNATTKC
KGKGICNNFGNCQCFPGHRPPDCKFQFGSPGGSIDDGNFQKSGDFYTEKGYNTHWNNW
FILSFCIFLPFFIVFTTVIFKRNEISKSCNRENAEYNRNSSVVSESDDVGH"
BASE COUNT 590 a 337 c 380 g 579 t
ORIGIN
1 atgttccttc tcctcgccct cctcactgag cttggaagac tgcaagccca cgaaggttct
61 gaaggaatat ttctgcatgt cacagttcca cggaagatta agtcaaatga cagtgaagtt
121 tcagagagga agatgattta catcattaca attgatggac aaccttacac tctacatctc
181 ggaaaacaat cattcttacc ccagaacttt ttggtttata catataatga aactggatct
241 ttgcattctg tgtctccata ttttatgatg cattgccatt accaaggata tgctgccgaa
301 tttccaaatt catttgtgac actcagtata tgttctggtc tcagataaaa aatctttcaa
361 aactattacc ccaatatctg gaaatataca ttatagtgga aaaagctttg tatgattata
421 tgggatctga aatgatggct gtaacacaaa aaattgtcca ggttattggg cttgtcaaca
481 ctatgtttac ccagttcaaa ttgactgtta tactgtcttc cttggaattg tggtcaaatg
541 aaaaccagat ttccaccagt ggggatgctg atgatatatt acaaagattt ttggcatgga
601 aacgggacta tctcatccta cggccccatg acatagcata cttacttgtt tacaggaaac
661 atcctaaata tgtgggagca acatttcctg gcactgtatg caataaaagc tatgatgcag
721 gtattgctat gtatccagat gcaataggtt tggagggatt ttcggttatt atagctcaac
781 tgcttggcct taatgtagga ttaacatatg atgacatcac tcagtgtttc tgtctgagag
841 ctacatgcat catgaatcat gaagcagtga atgtcaattt aagaagtgct gtgattataa
901 cacatgtaaa ctgaagggct cagtaaaatg tggttctgga ccatgttgta catcaaagtg
961 tgagttgtca atagcaggca ctccatgtag aaagagtatt gatccagagt gtgattttac
1021 agagtactgc aatggaacct ctagtaattg tgttcctgac acttatgcat tgaatggccg
1081 tttgtgcaag ttgggaactg cctattgcta taacggacaa tgtcaaacta ctgataacca
1141 gtgtgccaag atatttggaa aaggtgctca aggtgctcca tttgcctgtt ttaaagaagt
1201 taattctctg catgaaagat ctgaaaactg tggttttaaa aattcacaac cattaccttg
1261 tgaacggaag gatgttctct gtggaaaatt agcttgtgtt cagccacata aaaatgctaa
1321 taaaagtgac gctcaatcta cagtttattc atatattcaa gaccatgtat gtgtatctat
1381 agccactggt tcctccatga gatcagatgg aacagacaat gcctatgtgg ctgatggcac
1441 catgtgtggt ccagaaatgt actgtgtaaa taaaacctgc agaaaagttc atttaatggg
1501 atataactgt aatgccacca caaaatgcaa agggaaaggg atatgtaata attttggtaa
1561 ttgtcaatgc ttccctggac atagacctcc agattgtaaa ttccagtttg gttccccagg
1621 gggtagtatt gatgatggaa attttcagaa atctggtgac ttttatactg aaaaaggcta
1681 caatacacac tggaacaact ggtttattct gagtttctgc atttttctgc cgtttttcat
1741 agttttcacc actgtgatct ttaaaagaaa tgaaataagt aaatcatgta acagagagaa
1801 tgcagagtat aatcgtaatt catccgttgt atcagaaagc gatgacgtgg gacattaata
1861 ttgcacagaa cttccatagc aaataa
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