LOCUS BC118587 2063 bp mRNA linear HUM 01-JUL-2006
DEFINITION Homo sapiens protein inhibitor of activated STAT, 1, mRNA (cDNA
clone MGC:141879 IMAGE:40085010), complete cds.
ACCESSION BC118587
VERSION BC118587.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2063)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2063)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (30-JUN-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 26 Row: i Column: 17.
FEATURES Location/Qualifiers
source 1..2063
/db_xref="H-InvDB:HIT000387865"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:141879 IMAGE:40085010"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: GTGGAGCG"
gene 1..2063
/gene="PIAS1"
/gene_synonym="GBP"
/gene_synonym="GU/RH-II"
/db_xref="GeneID:8554"
/db_xref="HGNC:HGNC:2752"
/db_xref="MIM:603566"
CDS 51..2006
/gene="PIAS1"
/gene_synonym="GBP"
/gene_synonym="GU/RH-II"
/codon_start=1
/product="protein inhibitor of activated STAT, 1"
/protein_id="AAI18588.1"
/db_xref="GeneID:8554"
/db_xref="HGNC:HGNC:2752"
/db_xref="MIM:603566"
/translation="MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHL
LKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGH
PASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDN
SQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPN
LCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGR
NYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLL
CPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLF
MEILKYCTDCDEIQFKEDGTWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQS
SNKNKKVEVIDLTIDSSSDEEEEEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRT
PSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAA
AVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRES
HSHTVTNRSSTDTASIFGIIPDIISLD"
BASE COUNT 608 a 541 c 400 g 514 t
ORIGIN
1 tagcggcggc ccccggcgaa gttcactgcg cttgcgctga cagacgcaag atggcggaca
61 gtgcggaact aaagcaaatg gttatgagcc ttagagtttc tgaactccaa gtactgttgg
121 gctacgccgg gagaaacaag cacggacgca aacacgaact tctcacaaaa gccctgcatt
181 tgctaaaggc tggctgtagt cctgctgtgc aaatgaaaat taaggaactc tataggcggc
241 ggttcccaca gaaaatcatg acgcctgcag acttgtccat ccccaacgta cattcaagtc
301 ctatgccagc aactttgtct ccatctacca ttccacaact cacttacgat ggtcaccctg
361 catcatcgcc attactccct gtttctcttc tgggacctaa acatgaactg gaactcccac
421 atcttacatc agctcttcac ccagtccatc cggatataaa acttcaaaaa ttaccatttt
481 atgatttact ggatgaactg ataaaaccca ccagtctagc atcagacaac agtcagcgct
541 ttcgagaaac ctgttttgca tttgccttga caccacaaca agtgcagcaa atcagtagtt
601 ccatggatat ttctgggacc aaatgtgact tcacagtaca ggtccagtta aggttttgtt
661 tatcagaaac cagttgtcca caagaagatc acttcccacc caatctttgt gtgaaagtga
721 atacaaaacc ttgcagcctt ccaggttacc ttccacctac aaaaaatggc gtggaaccaa
781 agcgacccag ccgaccaatt aatatcacct cacttgtccg actgtccaca acagtaccaa
841 acacgattgt tgtttcttgg actgcagaaa ttggaagaaa ctattccatg gcagtatatc
901 ttgtaaaaca gttgtcctca acagttcttc ttcagaggtt acgagcaaag ggaataagga
961 atccggatca ttctagagct ttaattaaag agaagttgac tgcggatcca gacagtgaaa
1021 tagctacaac cagcctaagg gtttctctac tatgtccact tggtaaaatg cggctgacaa
1081 ttccgtgtcg ggcccttaca tgttctcatc tacaatgttt tgacgcaact ctttacattc
1141 agatgaatga gaaaaaacca acctgggttt gtcctgtctg tgataagaag gctccatatg
1201 aacaccttat tattgatggc ttgtttatgg aaatcctaaa gtactgtaca gactgtgatg
1261 aaatacaatt taaggaggat ggcacttggg caccgatgag atcaaaaaag gaagtacagg
1321 aagtttctgc ctcttacaat ggagtcgatg gatgcttgag ctccacattg gagcatcagg
1381 tagcgtctca ccaccagtcc tcaaataaaa acaagaaagt agaagtgatt gacctaacca
1441 tagacagttc atctgatgaa gaggaagaag agccatctgc caagaggacc tgtccttccc
1501 tatctcccac atcaccacta aataataaag gcattttaag tcttccacat caagcatctc
1561 cagtatcccg caccccaagc cttcctgctg tagacacaag ctacattaat acctccctca
1621 tccaagacta taggcatcct ttccacatga cacccatgcc ttacgactta caaggattag
1681 atttctttcc tttcttatca ggagacaatc agcattacaa cacctccttg cttgccgctg
1741 cagcagcagc agtttcagat gatcaagacc tcctacactc gtctcggttt ttcccgtata
1801 cctcctcaca gatgtttctt gatcagttaa gtgcaggagg cagtacttct ctgccaacca
1861 ccaatggaag cagtagtggc agtaacagca gcctggtttc ttccaacagc ctaagggaaa
1921 gccatagcca caccgtcaca aacaggagca gcacggacac ggcatccatc tttggcatca
1981 taccagacat tatttcattg gactgattcc caggccctgc tgctcccatc cccaccccag
2041 atcgaatgaa cttggcagaa aga
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