LOCUS BC117465 1740 bp mRNA linear HUM 26-JUN-2006
DEFINITION Homo sapiens keratin, hair, basic, 1, mRNA (cDNA clone MGC:151074
IMAGE:40126016), complete cds.
ACCESSION BC117465
VERSION BC117465.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1740)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1740)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 6 Row: O Column: 17.
FEATURES Location/Qualifiers
source 1..1740
/db_xref="H-InvDB:HIT000387753"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:151074 IMAGE:40126016"
/tissue_type="Brain, cerebral cortex and lung, PCR rescued
clones"
/clone_lib="NIH_MGC_322"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: GTAGTGAT"
gene 1..1740
/gene="KRTHB1"
/gene_synonym="ghHkb1"
/gene_synonym="Hb-1"
/gene_synonym="HB1"
/gene_synonym="hHAKB2-1"
/gene_synonym="MLN137"
/db_xref="GeneID:3887"
/db_xref="HGNC:HGNC:6458"
/db_xref="MIM:602153"
CDS 22..1539
/gene="KRTHB1"
/gene_synonym="ghHkb1"
/gene_synonym="Hb-1"
/gene_synonym="HB1"
/gene_synonym="hHAKB2-1"
/gene_synonym="MLN137"
/codon_start=1
/product="keratin, hair, basic, 1"
/protein_id="AAI17466.1"
/db_xref="GeneID:3887"
/db_xref="HGNC:HGNC:6458"
/db_xref="MIM:602153"
/translation="MTCGSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGG
FGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV
KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLPFYQNRECCQSNLEPLFEGYIE
TLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCA
YLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIIA
EIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA
EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEV
MNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTG
SVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRKC"
BASE COUNT 342 a 530 c 572 g 296 t
ORIGIN
1 acccaaacgt ccaggaggat catgacctgc ggatcaggat ttggtgggcg cgccttcagc
61 tgcatctcgg cctgcgggcc gcggcccggc cgctgctgca tcaccgccgc cccctaccgt
121 ggcatctcct gctaccgcgg cctcaccggg ggcttcggca gccacagcgt gtgcggaggc
181 tttcgggccg gctcctgcgg acgcagcttc ggctaccgct ccgggggcgt gtgcgggccc
241 agtcccccat gcatcaccac cgtgtcggtc aacgagagcc tcctcacgcc cctcaacctg
301 gagatcgacc ccaacgcgca gtgcgtgaag caggaggaga aggagcagat caagtccctc
361 aacagcaggt tcgcggcctt catcgacaag gtgcgcttcc tggagcagca gaacaaactg
421 ctggagacaa agctgccgtt ctaccagaac cgcgagtgtt gccagagcaa cctggagccc
481 ctgtttgagg gctacatcga gactctgcgg cgggaggccg agtgcgtgga ggccgacagc
541 gggaggctgg cctcagagct taaccacgtg caggaggtgc tggagggcta caagaagaag
601 tatgaggagg aggtttctct gagagcaaca gctgagaacg agtttgtggc tctgaagaag
661 gatgtggact gcgcctacct ccgcaagtca gacctggagg ccaacgtgga ggccctgatc
721 caggagatcg acttcctgag gcggctgtat gaggaggaga tccgcattct ccagtcgcac
781 atctcagaca cctccgtggt tgtcaagctg gacaacagcc gggacctgaa catggactgc
841 atcattgccg agattaaggc acagtatgac gacattgtca cccgcagccg ggccgaggcc
901 gagtcctggt accgcagcaa gtgtgaggag atgaaggcca cggtgatcag gcacggggag
961 accctgcgcc gcaccaagga ggagatcaac gagctgaacc gcatgatcca gaggctgacg
1021 gccgaggtgg agaatgccaa gtgccagaac tccaagctgg aggccgcggt ggcccagtct
1081 gagcagcagg gtgaggcggc cctcagtgat gcccgctgca agctggccga gctggagggc
1141 gccctgcaga aggccaagca ggacatggcc tgcctgatca gggagtacca ggaggtgatg
1201 aactccaagc tgggcctgga catcgagatc gccacctaca ggcgcctgct ggagggcgag
1261 gagcagaggc tatgtgaagg cattggggct gtgaatgtct gtgtcagcag ctcccggggc
1321 ggggtcgtgt gcggggacct ctgcgtgtca ggctcccggc cagtgactgg cagtgtctgc
1381 agcgctccgt gcaacgggaa cgtggcggtg agcaccggcc tgtgtgcgcc ctgcggccaa
1441 ttgaacacca cctgcggagg gggttcctgc ggcgtgggct cctgtggtat cagctccctg
1501 ggtgtggggt cttgcggcag cagctgccgg aaatgttagg caccccaact caagtcccag
1561 gccccaggcg tctttcctgc cctgccttgc ttggcccatc cagtccaggc gcctggagca
1621 agtgctcagc tacttctcct ccactttgaa agacccctcc cactcctggc ctcacatttc
1681 tctgtgtgat cccccacttc tgggctctgc caccccacag tgggaaaggc caccctagaa
//