LOCUS BC117443 3275 bp mRNA linear HUM 26-JUN-2006
DEFINITION Homo sapiens integrin, alpha 2b (platelet glycoprotein IIb of
IIb/IIIa complex, antigen CD41), mRNA (cDNA clone MGC:151052
IMAGE:40125994), complete cds.
ACCESSION BC117443
VERSION BC117443.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3275)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3275)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 6 Row: N Column: 19.
FEATURES Location/Qualifiers
source 1..3275
/db_xref="H-InvDB:HIT000387731"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:151052 IMAGE:40125994"
/tissue_type="Lung, PCR rescued clones"
/clone_lib="NIH_MGC_298"
/note="Vector: pCR4-TOPO; Clone identification sequence
tag: TGGAACTA"
gene 1..3275
/gene="ITGA2B"
/gene_synonym="CD41"
/gene_synonym="CD41B"
/gene_synonym="GPIIb"
/gene_synonym="GTA"
/gene_synonym="HPA3"
/db_xref="GeneID:3674"
/db_xref="HGNC:HGNC:6138"
/db_xref="MIM:607759"
CDS 27..3146
/gene="ITGA2B"
/gene_synonym="CD41"
/gene_synonym="CD41B"
/gene_synonym="GPIIb"
/gene_synonym="GTA"
/gene_synonym="HPA3"
/codon_start=1
/product="integrin, alpha 2b (platelet glycoprotein IIb of
IIb/IIIa complex, antigen CD41)"
/protein_id="AAI17444.1"
/db_xref="GeneID:3674"
/db_xref="HGNC:HGNC:6138"
/db_xref="MIM:607759"
/translation="MARALCPLQALWLLEWVLLLLGPCAAPPAWALNLDPVQLTFYAG
PNGSQFGFSLDFHKDSHGRVAIVVGAPRTLGPSQEETGGVFLCPWRAEGGQCPSLLFD
LRDETRNVGSQTLQTFKARQGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGS
CFLAQPESGRRAEYSPCRGNTLSRIYVENDFSWDKRYCEAGFSSVVTQAGELVLGAPG
GYYFLGLLAQAPVADIFSSYRPGILLWHVSSQSLSFDSSNPEYFDGYWGYSVAVGEFD
GDLNTTEYVVGAPTWSWTLGAVEILDSYYQRLHRLRGEQMASYFGHSVAVTDVNGDGR
HDLLVGAPLYMESRADRKLAEVGRVYLFLQPRGPHALGAPSLLLTGTQLYGRFGSAIA
PLGDLDRDGYNDIAVAAPYGGPSGRGQVLVFLGQSEGLRSRPSQVLDSPFPTGSAFGF
SLRGAVDIDDNGYPDLIVGAYGANQVAVYRAQPVVKASVQLLVQDSLNPAVKSCVLPQ
TKTPVSCFNIQMCVGATGHNIPQKLSLNAELQLDRQKPRQGRRVLLLGSQQAGTTLNL
DLGGKHSPICHTTMAFLRDEADFRDKLSPIVLSLNVSLPPTEAGMAPAVVLHGDTHVQ
EQTRIVLDCGEDDVCVPQLQLTASVTGSPLLVGADNVLELQMDAANEGEGAYEAELAV
HLPQGAHYMRALSNVEGFERLICNQKKENETRVVLCELGNPMKKNAQIGIAMLVSVGN
LEEAGESVSFQLQIRSKNSQNPNSKIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGE
REQNSLDSWGPKVEHTYELHNNGPGTVNGLHLSIHLPGQSQPSDLLYILDIQPQGGLQ
CFPQPPVNPLKVDWGLPIPSPSPIHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCDSA
PCTVVQCDLQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPP
LSLPRGEAQVWTQLLRALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPP
LEEDDEEGE"
BASE COUNT 612 a 978 c 1028 g 657 t
ORIGIN
1 gcctgggagg ttgtggaaga aggaagatgg ccagagcttt gtgtccactg caagccctct
61 ggcttctgga gtgggtgctg ctgctcttgg gaccttgtgc tgcccctcca gcctgggcct
121 tgaacctgga cccagtgcag ctcaccttct atgcaggccc caatggcagc cagtttggat
181 tttcactgga cttccacaag gacagccatg ggagagtggc catcgtggtg ggcgccccgc
241 ggaccctggg ccccagccag gaggagacgg gcggcgtgtt cctgtgcccc tggagggccg
301 agggcggcca gtgcccctcg ctgctctttg acctccgtga tgagacccga aatgtaggct
361 cccaaacttt acaaaccttc aaggcccgcc aaggactggg ggcgtcggtc gtcagctgga
421 gcgacgtcat tgtggcctgc gccccctggc agcactggaa cgtcctagaa aagactgagg
481 aggctgagaa gacgcccgta ggtagctgct ttttggctca gccagagagc ggccgccgcg
541 ccgagtactc cccctgtcgc gggaacaccc tgagccgcat ttacgtggaa aatgatttta
601 gctgggacaa gcgttactgt gaagcgggct tcagctccgt ggtcactcag gccggagagc
661 tggtgcttgg ggctcctggc ggctattatt tcttaggtct cctggcccag gctccagttg
721 cggatatttt ctcgagttac cgcccaggca tccttttgtg gcacgtgtcc tcccagagcc
781 tctcctttga ctccagcaac ccagagtact tcgacggcta ctgggggtac tcggtggccg
841 tgggcgagtt cgacggggat ctcaacacta cagaatatgt cgtcggtgcc cccacttgga
901 gctggaccct gggagcggtg gaaattttgg attcctacta ccagaggctg catcggctgc
961 gcggagagca gatggcgtcg tattttgggc attcagtggc tgtcactgac gtcaacgggg
1021 atgggaggca tgatctgctg gtgggcgctc cactgtatat ggagagccgg gcagaccgaa
1081 aactggccga agtggggcgt gtgtatttgt tcctgcagcc gcgaggcccc cacgcgctgg
1141 gtgcccccag cctcctgctg actggcacac agctctatgg gcgattcggc tctgccatcg
1201 cacccctggg cgacctcgac cgggatggct acaatgacat tgcagtggct gccccctacg
1261 ggggtcccag tggccggggc caagtgctgg tgttcctggg tcagagtgag gggctgaggt
1321 cacgtccctc ccaggtcctg gacagcccct tccccacagg ctctgccttt ggcttctccc
1381 ttcgaggtgc cgtagacatc gatgacaacg gatacccaga cctgatcgtg ggagcttacg
1441 gggccaacca ggtggctgtg tacagagctc agccagtggt gaaggcctct gtccagctac
1501 tggtgcaaga ttcactgaat cctgctgtga agagctgtgt cctacctcag accaagacac
1561 ccgtgagctg cttcaacatc cagatgtgtg ttggagccac tgggcacaac attcctcaga
1621 agctatccct aaatgccgag ctgcagctgg accggcagaa gccccgccag ggccggcggg
1681 tgctgctgct gggctctcaa caggcaggca ccaccctgaa cctggatctg ggcggaaagc
1741 acagccccat ctgccacacc accatggcct tccttcgaga tgaggcagac ttccgggaca
1801 agctgagccc cattgtgctc agcctcaatg tgtccctacc gcccacggag gctggaatgg
1861 cccctgctgt cgtgctgcat ggagacaccc atgtgcagga gcagacacga atcgtcctgg
1921 actgtgggga agatgacgta tgtgtgcccc agcttcagct cactgccagc gtgacgggct
1981 ccccgctcct agttggggca gataatgtcc tggagctgca gatggacgca gccaacgagg
2041 gcgagggggc ctatgaagca gagctggccg tgcacctgcc ccagggcgcc cactacatgc
2101 gggccctaag caatgtcgag ggctttgaga gactcatctg taatcagaag aaggagaatg
2161 agaccagggt ggtgctgtgt gagctgggca accccatgaa gaagaacgcc cagataggaa
2221 tcgcgatgtt ggtgagcgtg gggaatctgg aagaggctgg ggagtctgtg tccttccagc
2281 tgcagatacg gagcaagaac agccagaatc caaacagcaa gattgtgctg ctggacgtgc
2341 cggtccgggc agaggcccaa gtggagctgc gagggaactc ctttccagcc tccctggtgg
2401 tggcagcaga agaaggtgag agggagcaga acagcttgga cagctgggga cccaaagtgg
2461 agcacaccta tgagctccac aacaatggcc ctgggactgt gaatggtctt cacctcagca
2521 tccaccttcc gggacagtcc cagccctccg acctgctcta catcctggat atacagcccc
2581 aggggggcct tcagtgcttc ccacagcctc ctgtcaaccc tctcaaggtg gactgggggc
2641 tgcccatccc cagcccctcc cccattcacc cggcccatca caagcgggat cgcagacaga
2701 tcttcctgcc agagcccgag cagccctcga ggcttcagga tccagttctc gtaagctgcg
2761 actcggcgcc ctgtactgtg gtgcagtgtg acctgcagga gatggcgcgc gggcagcggg
2821 ccatggtcac ggtgctggcc ttcctgtggc tgcccagcct ctaccagagg cctctggatc
2881 agtttgtgct gcagtcgcac gcatggttca acgtgtcctc cctcccctat gcggtgcccc
2941 cgctcagcct gccccgaggg gaagctcagg tgtggacaca gctgctccgg gccttggagg
3001 agagggccat tccaatctgg tgggtgctgg tgggtgtgct gggtggcctg ctgctgctca
3061 ccatcctggt cctggccatg tggaaggtcg gcttcttcaa gcggaaccgg ccacccctgg
3121 aagaagatga tgaagagggg gagtgatggt gcagcctaca ctattctagc aggagggttg
3181 ggcgtgctac ctgcaccgcc ccttctccaa caagttgcct ccaagctttg ggttggagct
3241 gttccattgg gtcctcttgg tgtcgtttcc ctccc
//