LOCUS BC117417 3725 bp mRNA linear HUM 26-JUN-2006
DEFINITION Homo sapiens sortilin-related VPS10 domain containing receptor 3,
mRNA (cDNA clone MGC:151026 IMAGE:40125968), complete cds.
ACCESSION BC117417
VERSION BC117417.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3725)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3725)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 6 Row: M Column: 17.
FEATURES Location/Qualifiers
source 1..3725
/db_xref="H-InvDB:HIT000387707"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:151026 IMAGE:40125968"
/tissue_type="Brain, cerebral cortex and lung, PCR rescued
clones"
/clone_lib="NIH_MGC_323"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: CGTGGTCA"
gene 1..3725
/gene="SORCS3"
/gene_synonym="RP11-107L7.1"
/gene_synonym="SORCS"
/db_xref="GeneID:22986"
/db_xref="HGNC:HGNC:16699"
/db_xref="MIM:606285"
CDS 44..3712
/gene="SORCS3"
/gene_synonym="RP11-107L7.1"
/gene_synonym="SORCS"
/codon_start=1
/product="sortilin-related VPS10 domain containing
receptor 3"
/protein_id="AAI17418.1"
/db_xref="GeneID:22986"
/db_xref="HGNC:HGNC:16699"
/db_xref="MIM:606285"
/translation="MEAARTERPAGRPGAPLVRTGLLLLSTWVLAGAEITWDATGGPG
RPAAPASRPPALSPLSPRAVASQWPEELASARRAAVLGRRAGPELLPQQGGGRGSEMQ
VEAGGTSPAGERRGRGIPAPAKLGGARRSRRAQPPITQERGDAWATAPADGSRGSRPL
AKGSREEVKAPRAGGSAAEDLRLPSTSFALTGDSAHNQAMVHWSGHNSSVILILTKLY
DFNLGSVTESSLWRSTDYGTTYEKLNDKVGLKTVLSYLYVNPTNKRKIMLLSDPEMES
SILISSDEGATYQKYRLTFYIQSLLFHPKQEDWVLAYSLDQKLYSSMDFGRRWQLMHE
RITPNRFYWSVAGLDKEADLVHMEVRTTDGYAHYLTCRIQECAETTRSGPFARSIDIS
SLVVQDEYIFIQVTTSGRASYYVSYRREAFAQIKLPKYSLPKDMHIISTDENQVFAAV
QEWNQNDTYNLYISDTRGIYFTLAMENIKSSRGLMGNIIIELYEVAGIKGIFLANKKV
DDQVKTYITYNKGRDWRLLQAPDVDLRGSPVHCLLPFCSLHLHLQLSENPYSSGRISS
KETAPGLVVATGNIGPELSYTDIGVFISSDGGNTWRQIFDEEYNVWFLDWGGALVAMK
HTPLPVRHLWVSFDEGHSWDKYGFTSVPLFVDGALVEAGMETHIMTVFGHFSLRSEWQ
LVKVDYKSIFSRHCTKEDYQTWHLLNQGEPCVMGERKIFKKRKPGAQCALGRDHSGSV
VSEPCVCANWDFECDYGYERHGESQCVPAFWYNPASPSKDCSLGQSYLNSTGYRRIVS
NNCTDGLREKYTAKAQMCPGKAPRGLHVVTTDGRLVAEQGHNATFIILMEEGDLQRTN
IQLDFGDGIAVSYANFSPIEDGIKHVYKSAGIFQVTAYAENNLGSDTAVLFLHVVCPV
EHVHLRVPFVAIRNKEVNISAVVWPSQLGTLTYFWWFGNSTKPLITLDSSISFTFLAE
GTDTITVQVAAGNALIQDTKEIAVHEYFQSQLLSFSPNLDYHNPDIPEWRKDIGNVIK
RALVKVTSVPEDQILIAVFPGLPTSAELFILPPKNLTERRKGNEGDLEQIVETLFNAL
NQNLVQFELKPGVQVIVYVTQLTLAPLVDSSAGHSSSAMLMLLSVVFVGLAVFLIYKF
KRKIPWINIYAQVQHDKEQEMIGSVSQSENAPKITLSDFTEPEELLDKELDTRVIGGI
ATIANSESTKEIPNCTSV"
BASE COUNT 911 a 973 c 1055 g 786 t
ORIGIN
1 gcgccacaca ctcggcagcc cgagccgcgg tagccgcagc gggatggagg cggcgcgcac
61 ggagcgcccc gcaggcaggc cgggggcgcc gcttgtccgg acggggctcc tactcttgtc
121 gacgtgggtc ctggccggcg ccgagatcac ttgggacgcg acaggcggtc ccggacgccc
181 ggcggccccg gcttcgcggc caccggcgtt gtctccactc tcgccgcggg cagtggccag
241 ccagtggccg gaggagctgg cgtcggcgcg gagagccgcc gtgctggggc gccgggccgg
301 accagagctg ctgccccagc agggcggcgg cagaggcagt gagatgcagg tggaagccgg
361 agggacatca ccggcaggcg agcggcgggg ccggggcatc ccagctcctg ccaagcttgg
421 cggcgcgagg aggagtcgcc gggcgcagcc cccaatcacc caggaacgcg gggacgcctg
481 ggccactgct ccggccgatg gttccagagg aagccgtccc cttgctaagg gttcccggga
541 ggaggtgaag gcgccgcggg ctggggggtc ggcggctgaa gacctccggc tgcccagcac
601 ctccttcgcg ctgaccgggg actcggccca caaccaagcc atggtgcact ggtcgggaca
661 caacagcagc gtcatactta tcctgacgaa gctgtatgac ttcaacctgg gcagcgtgac
721 tgagagttca ctatggaggt cgacagatta tggcaccacc tatgaaaagc tgaatgacaa
781 agtgggtttg aagactgtcc tcagttacct ctatgtcaat ccaaccaaca aaaggaagat
841 tatgcttctc agtgatcctg agatggagag cagcatattg atcagctcag acgaaggggc
901 gacctatcag aagtatcggc tcaccttcta tatccagagc ctgctctttc atcccaagca
961 agaggactgg gtgctggcct acagtttgga tcaaaagctc tacagctcca tggactttgg
1021 aagacggtgg caactcatgc atgaacgcat cacacccaac aggttttatt ggtcggtggc
1081 cggattggat aaggaggcgg acctggtgca catggaggtg cggaccacgg atggatatgc
1141 tcactacctc acctgcagga tccaggaatg tgccgagaca actagaagtg ggccttttgc
1201 ccgctccatt gacatcagtt ccctggttgt ccaggatgaa tatatcttca ttcaggtaac
1261 aactagtgga agagccagct actacgtgtc ttatcgaaga gaggcctttg ctcagataaa
1321 gctgcctaag tactcgttgc caaaggacat gcacatcatc agtacagacg agaaccaagt
1381 atttgctgcg gtccaagaat ggaaccagaa tgacacgtac aacctctaca tctcagacac
1441 gcgtgggatt tacttcactc tggccatgga gaacatcaag agcagcagag gtctaatggg
1501 gaacatcatt attgaattgt atgaggtagc aggtatcaaa gggatatttc tggcaaacaa
1561 gaaggtggac gaccaggtga agacatacat cacttacaac aaaggcaggg attggcgcct
1621 gctgcaagct ccggatgtgg acctgagagg aagcccagtg cactgcctgc tgcccttctg
1681 ttccttacat ctgcacctgc aactctctga aaatccatat tcctcaggaa gaatctctag
1741 caaggagaca gccccaggac ttgtggtggc tacaggcaac attggcccgg agctctcata
1801 tactgatatt ggtgtgttca tctcctccga tgggggcaac acatggagac agatctttga
1861 tgaagagtac aatgtctggt tcctagactg gggtggtgcc ctcgtggcca tgaaacacac
1921 acctctgcca gtcaggcatt tgtgggtgag ttttgatgag ggccactctt gggacaagta
1981 tggtttcact tcggttcctc tctttgttga cggggctctg gtggaggcag gaatggagac
2041 ccacatcatg acagtttttg gccacttcag cctccgctcc gaatggcaat tggtgaaagt
2101 ggactacaaa tctatcttca gccggcattg caccaaggag gactatcaga cctggcacct
2161 gctcaatcag ggagagcctt gtgtcatggg agaaaggaaa atattcaaga aacgtaagcc
2221 aggagctcag tgtgccctgg gccgagacca ctcaggatca gtggtctcag aaccctgtgt
2281 ctgtgccaat tgggacttcg agtgtgacta tgggtatgag agacatgggg agagccagtg
2341 tgtcccagct ttctggtaca atccagcatc cccatcaaag gactgcagcc ttggtcaaag
2401 ctaccttaac agcactgggt atcggcggat tgtgtccaac aactgcacag atgggctaag
2461 ggagaagtac accgccaagg cccagatgtg ccctggaaaa gcccctcggg gcctccatgt
2521 ggtgacgacc gatgggcggc tggtggcaga gcaggggcac aatgcaactt tcatcatcct
2581 catggaggag ggtgatctac aaaggacaaa catccagctt gactttgggg atgggattgc
2641 tgtgtcctac gcaaacttca gccccatcga ggacggcatc aagcacgtgt ataagagtgc
2701 ggggatcttc caggtgacag cctatgcaga gaacaacctt ggctcagaca cagctgtcct
2761 cttcctgcat gtggtttgtc ctgtggagca tgttcatctc cgagttccat ttgttgccat
2821 aagaaataag gaggtcaaca tcagtgcagt cgtgtggccc agtcaactgg ggacccttac
2881 ctatttctgg tggttcggca atagcacaaa gcctctcatc actttggaca gcagcatttc
2941 cttcacattc cttgcagaag gaaccgacac catcacagtc caggtggctg ctgggaatgc
3001 cctcatccag gacacaaaag agattgcagt tcatgaatat ttccagtccc agcttttatc
3061 attctctcct aatctggatt accacaatcc tgacattcct gagtggagaa aagatattgg
3121 caatgtcatc aagcgagctc tggttaaagt aaccagtgtc ccagaggacc agatcctcat
3181 tgccgtgttt cctggtctcc ccacttcagc agagcttttc attcttccac ccaagaacct
3241 gacagagagg aggaaaggca atgaagggga cctggaacaa attgtagaaa cactgtttaa
3301 tgctctcaac caaaatttgg tccagtttga gctgaagccg ggggtacaag tcattgtgta
3361 tgtcacacag ctgacgttag ctccattggt ggactccagt gctgggcaca gcagctcagc
3421 catgcttatg ctattatcag tggtatttgt tggcctggct gtgtttttga tctacaagtt
3481 taaaaggaaa atcccttgga ttaacatcta tgctcaagtc caacacgaca aggagcagga
3541 gatgattggg tcagtgagcc aaagtgaaaa cgcccccaaa atcacactca gtgactttac
3601 ggagcctgag gagctgctgg acaaagagct ggacacgcgg gtcataggag gcattgccac
3661 tattgcaaac agcgaaagca caaaggagat ccccaactgc actagtgttt aataccagca
3721 agcca
//