LOCUS BC117257 3859 bp mRNA linear HUM 03-NOV-2008
DEFINITION Homo sapiens diaphanous homolog 1 (Drosophila), mRNA (cDNA clone
MGC:150866 IMAGE:40125808), complete cds.
ACCESSION BC117257
VERSION BC117257.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3859)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3859)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 6 Row: G Column: 1.
FEATURES Location/Qualifiers
source 1..3859
/db_xref="H-InvDB:HIT000387547"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:150866 IMAGE:40125808"
/tissue_type="Lung and heart, PCR rescued clones"
/clone_lib="NIH_MGC_317"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: CATGTCCA"
gene 1..3859
/gene="DIAPH1"
/gene_synonym="DIA1"
/gene_synonym="DRF1"
/gene_synonym="hDIA1"
/gene_synonym="LFHL1"
/db_xref="GeneID:1729"
/db_xref="HGNC:HGNC:2876"
/db_xref="MIM:602121"
CDS 19..3807
/gene="DIAPH1"
/gene_synonym="DIA1"
/gene_synonym="DRF1"
/gene_synonym="hDIA1"
/gene_synonym="LFHL1"
/codon_start=1
/product="DIAPH1 protein"
/protein_id="AAI17258.1"
/db_xref="GeneID:1729"
/db_xref="HGNC:HGNC:2876"
/db_xref="MIM:602121"
/translation="MEPPGGSLGPGRGTRDKKKGRSPDELPSAGGDGGKSKKFLERFT
SMRIKKEKEKPNSAHRNSSASYGDDPTAQSLQDVSDEQVLVLFEQMLLDMNLNEEKQQ
PLREKDIIIKREMVSQYLYTSKAGMSQKESSKSAMMYIQELRSGLRDMPLLSCLESLR
VSLNNNPVSWVQTFGAEGLASLLDILKRLHDEKEETAGSYDSRNKHEIIRCLKAFMNN
KFGIKTMLETEEGILLLVRAMDPAVPNMMIDAAKLLSALCILPQPEDMNERVLEAMTE
RAEMDEVERFQPLLDGLKSGTTIALKVGCLQLINALITPAEELDFRVHIRSELMRLGL
HQVLQDLREIENEDMRVQLNVFDEQGEEDSYDLKGRLDDIRMEMDDFNEVFQILLNTV
KDSKAEPHFLSILQHLLLVRNDYEARPQYYKLIEECISQIVLHKNGADPDFKCRHLQI
EIEGLIDQMIDKTKVEKSEAKAAELEKKLDSELTARHELQVEMKKMESDFEQKLQDLQ
GEKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPS
VPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPLPGGVCISSPPSLP
GGTAISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPP
PLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGIPPPPPGMGMPPP
PPFGFGVPAAPVLPFGLTPKKLYKPEVQLRRPNWSKLVAEDLSQDCFWTKVKEDRFEN
NELFAKLTLTFSAQTKTSKAKKDQEGGEEKKSVQKKKVKELKVLDSKTAQNLSIFLGS
FRMPYQEIKNVILEVNEAVLTESMIQNLIKQMPEPEQLKMLSELKDEYDDLAESEQFG
VVMGTVPRLRPRLNAILFKLQFSEQVENIKPEIVSVTAACEELRKSESFSNLLEITLL
VGNYMNAGSRNAGAFGFNISFLCKLRDTKSTDQKMTLLHFLAELCENDYPDVLKFPDE
LAHVEKASRVSAENLQKNLDQMKKQISDVERDVQNFPAATDEKDKFVEKMTSFVKDAQ
EQYNKLRMMHSNMETLYKELGEYFLFDPKKLSVEEFFMDLHNFRNMFLQAVKENQKRR
ETEEKMRRAKLAKEKAEKERLEKQQKREQLIDMNAEGDETGVMDSLLEALQSGAAFRR
KRGPRQANRKAGCAVTSLLASELTKDDAMAAVPAKVSKNSETFPTILEEAKELVGRAS
"
BASE COUNT 1037 a 939 c 986 g 897 t
ORIGIN
1 gccagcgtga accgggacat ggagccgccc ggcgggagcc tggggcccgg ccgcgggacc
61 cgggacaaga agaagggccg gagcccagat gagctgccct cggcgggcgg cgacggcggc
121 aaatctaaga aatttctgga gagatttacc agcatgagaa ttaagaagga gaaggaaaag
181 cccaattctg ctcatagaaa ttcttctgca tcatatgggg atgatcccac agcacagtca
241 ttgcaagatg tttcagatga acaagtgctg gttctctttg aacagatgct gctggatatg
301 aacctgaatg aggagaaaca gcaacctttg agggagaagg acatcatcat caagagggag
361 atggtgtccc aatacttgta cacctccaag gctggcatga gccagaagga gagctctaag
421 tctgccatga tgtatattca ggagttgagg tcaggcttgc gggatatgcc tctgctcagc
481 tgcctggagt cccttcgtgt gtctctcaac aacaaccctg tcagttgggt gcaaacattt
541 ggtgctgaag gcttggcctc cttattggac attcttaaac gacttcatga tgagaaagaa
601 gagactgctg ggagttacga tagccggaac aagcatgaga tcattcgctg cttgaaagct
661 tttatgaaca acaagtttgg aatcaagacc atgttggaga cagaagaagg aatcctactg
721 ctggtcagag ccatggatcc tgctgttccc aacatgatga ttgatgcagc taagctgctt
781 tctgctcttt gtattctacc gcagccagag gacatgaatg aaagggtttt ggaggcaatg
841 acagaaagag ctgagatgga tgaagtggaa cgtttccagc cgctgctgga tggattaaaa
901 agtggaacca ctattgcact gaaggttgga tgcctacagc tgatcaatgc tctcatcaca
961 ccagcggagg aacttgactt ccgagttcac atcagaagtg aactgatgcg tttggggcta
1021 catcaggtgt tgcaggacct tcgagagatt gaaaatgaag atatgagagt gcaactaaat
1081 gtgtttgatg aacaagggga agaggattcc tatgacctga agggacggct ggatgacatt
1141 cgcatggaga tggatgactt taatgaagtc tttcagattc tcttaaacac agtgaaggat
1201 tcaaaggcag agccacactt cctttccatc ctgcagcact tactcttggt ccgaaatgac
1261 tatgaggcca gacctcagta ctataagttg attgaagaat gtatttccca gatagttctg
1321 cacaagaacg gggctgatcc tgacttcaag tgccggcacc tccagattga gattgaggga
1381 ttaattgatc aaatgattga taagacaaag gtggagaaat ctgaagccaa agctgcagag
1441 ctggaaaaga agttggactc agagttaaca gcccgacatg agctacaggt ggaaatgaaa
1501 aagatggaaa gtgactttga gcagaagctt caagatcttc agggagaaaa agatgcactg
1561 cattctgaaa agcagcaaat tgccacagag aaacaggacc tggaagcaga ggtgtcccag
1621 ctcacaggag aggttgccaa gctgacaaag gaactggaag atgccaagaa agaaatggct
1681 tccctctctg cggcagctat tactgtacct ccttctgttc ctagtcgtgc tcctgttccc
1741 cctgcccctc ctttacctgg tgactctggc actattattc caccaccacc tgctcctggg
1801 gatagtacca ctcctcctcc tcctcctcct cctcctcctc cacctccttt gcctgggggt
1861 gtttgcatct cctcaccccc ttctttacct ggaggtactg ctatctctcc accccctcct
1921 ttgtctgggg atgctaccat ccctccaccc cctcctttgc ctgagggtgt tggcatccct
1981 tcaccctctt ctttgcctgg aggtactgcc atccccccac ctcctccttt gcctgggagt
2041 gctagaatcc ccccaccacc acctcctttg cctgggagtg ctggaattcc ccccccacct
2101 cctcccttgc ctggagaagc aggaatgcca cctcctcctc cccctcttcc tggtggtcct
2161 ggaatccctc cacctcctcc atttcccgga ggccctggca ttcctccacc tccacccgga
2221 atgggtatgc ctccacctcc cccatttgga tttggagttc ctgcagcccc agttctgcca
2281 tttggattaa cccccaaaaa gctttataag ccagaggtgc agctccggag gccaaactgg
2341 tccaagcttg tggctgagga cctctcccag gactgcttct ggacaaaggt gaaggaggac
2401 cgctttgaga acaatgaact tttcgccaaa cttaccctta ccttctctgc ccagaccaag
2461 acttccaaag ccaagaagga tcaagaaggt ggagaagaaa agaaatctgt gcaaaagaaa
2521 aaagtaaaag agttaaaggt gttggattca aagacagccc agaatctctc aatctttttg
2581 ggttccttcc gcatgcccta tcaagagatt aagaatgtca tcctggaggt gaatgaggct
2641 gttctgactg agtctatgat ccagaacctc attaagcaaa tgccagagcc agagcagtta
2701 aaaatgcttt ctgaactgaa ggatgaatat gatgacctgg ctgagtcaga gcagtttggc
2761 gtggtgatgg gcactgtgcc ccgactgcgg cctcgcctca atgccattct cttcaagcta
2821 caattcagcg agcaagtgga gaatatcaag ccagagattg tgtctgtcac tgctgcatgt
2881 gaggagttac gtaagagtga gagcttttcc aatctcctag agattacctt gcttgttgga
2941 aattacatga atgctggctc cagaaatgct ggtgcttttg gcttcaatat cagcttcctc
3001 tgtaagcttc gagacaccaa gtccacagat cagaagatga cgttgttaca cttcttggct
3061 gagttgtgtg agaatgacta tcccgatgtc ctcaagtttc cagacgagct tgcccatgtg
3121 gagaaagcca gccgagtttc tgctgaaaac ttgcaaaaga acctagatca gatgaagaaa
3181 caaatttctg atgtggaacg tgatgttcag aatttcccag ctgccacaga tgaaaaagac
3241 aagtttgttg aaaaaatgac cagctttgtg aaggatgcac aggaacagta taacaagctg
3301 cggatgatgc attctaacat ggagaccctc tataaggagc tgggcgagta cttcctcttt
3361 gaccccaaga agttgtctgt tgaagaattt ttcatggatc ttcacaattt tcggaatatg
3421 tttttgcaag cagtcaagga gaaccagaag cggcgggaga cagaagaaaa gatgaggcga
3481 gcaaaactag ccaaggagaa ggcagagaag gagcggctag agaagcagca gaagagagag
3541 caactcatag acatgaatgc agagggcgat gagacaggtg tgatggacag tcttctagaa
3601 gccctgcagt caggggcagc attccgacgg aagagagggc cccgtcaagc caacaggaag
3661 gccgggtgtg cagtcacatc tctgctagct tcggagctga ccaaggatga tgccatggct
3721 gctgttcctg ccaaggtgtc caagaacagt gagacattcc ccacaatcct tgaggaagcc
3781 aaggagttgg ttggccgtgc aagctaatgt gggtcctgtg accgcggcag ctcctcagcg
3841 gagccgcaga ctgtcctgc
//