LOCUS BC117216 2011 bp mRNA linear HUM 01-SEP-2006
DEFINITION Homo sapiens mitogen-activated protein kinase 4, mRNA (cDNA clone
MGC:150825 IMAGE:40125767), complete cds.
ACCESSION BC117216
VERSION BC117216.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2011)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2011)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 6 Row: E Column: 8.
FEATURES Location/Qualifiers
source 1..2011
/db_xref="H-InvDB:HIT000387506"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:150825 IMAGE:40125767"
/tissue_type="Cerebellum, Lung, PCR rescued clones"
/clone_lib="NIH_MGC_346"
/lab_host="DH10B"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: CGTACGGC"
gene 1..2011
/gene="MAPK4"
/gene_synonym="ERK3"
/gene_synonym="Erk4"
/gene_synonym="p63MAPK"
/db_xref="GeneID:5596"
/db_xref="HGNC:HGNC:6878"
/db_xref="MIM:176949"
CDS 55..1818
/gene="MAPK4"
/gene_synonym="ERK3"
/gene_synonym="Erk4"
/gene_synonym="p63MAPK"
/codon_start=1
/product="mitogen-activated protein kinase 4"
/protein_id="AAI17217.1"
/db_xref="GeneID:5596"
/db_xref="HGNC:HGNC:6878"
/db_xref="MIM:176949"
/translation="MAEKGDCIASVYGYDLGGRFVDFQPLGFGVNGLVLSAVDSRACR
KVAVKKIALSDARSMKHALREIKIIRRLDHDNIVKVYEVLGPKGTDLQGELFKFSVAY
IVQEYMETDLARLLEQGTLAEEHAKLFMYQLLRGLKYIHSANVLHRDLKPANIFISTE
DLVLKIGDFGLARIVDQHYSHKGYLSEGLVTKWYRSPRLLLSPNNYTKAIDMWAAGCI
LAEMLTGRMLFAGAHELEQMQLILETIPVIREEDKDELLRVMPSFVSSTWEVKRPLRK
LLPEVNSEAIDFLEKILTFNPMDRLTAEMGLQHPYMSPYSCPEDEPTSQHPFRIEDEI
DDIVLMAANQSQLSNWDTCSSRYPVSLSSDLEWRPDRCQDASEVQRDPRAGSAPLAED
VQVDPRKDSHSSSERFLEQSHSSMERAFEADYGRSCDYKVGSPSYLDKLLWRDNKPHH
YSEPKLILDLSHWKQAAGAPPTATGLADTGAREDEPASLFLEIAQWVKSTQGGPEHAS
PPADDPERRLSASPPGRPAPVDGGASPQFDLDVFISRALKLCTKPEDLPDNKLGDLNG
ACIPEHPGDLVQTEAFSKERW"
BASE COUNT 404 a 642 c 619 g 346 t
ORIGIN
1 cctttcctga ctgcccctgt gttacctggg cagctccaga tcactgagcc cacaatggct
61 gagaagggtg actgcatcgc cagtgtctat gggtatgacc tcggtgggcg ctttgttgac
121 ttccaacccc tgggcttcgg tgtcaatggt ttggtgctgt cggccgtgga cagccgggcc
181 tgccggaagg tcgctgtgaa gaagattgcc ctgagcgatg cccgcagcat gaagcacgcg
241 ctccgagaga tcaagatcat tcggcgcctg gaccacgaca acatcgtcaa agtgtacgag
301 gtgctcggtc ccaagggcac tgacctgcag ggtgagctgt tcaagttcag cgtggcgtac
361 atcgtccagg agtacatgga gaccgacctg gcacgcctgc tggagcaggg cacgctggca
421 gaagagcatg ccaagctgtt catgtaccag ctgctccgcg ggctcaagta catccactcc
481 gccaacgtgc tgcacaggga cctgaagccc gccaacatct tcatcagcac agaggacctc
541 gtgctcaaga ttggggattt cgggttggca aggatcgttg atcagcatta ctcccacaag
601 ggttatctgt cagaagggtt ggtaacaaag tggtaccgtt ccccacgact gctcctttcc
661 cccaataact acaccaaagc catcgacatg tgggccgccg gctgcatcct ggctgagatg
721 cttacgggga gaatgctctt tgctggggcc catgagctgg agcagatgca actcatcctg
781 gagaccatcc ctgtaatccg ggaggaagac aaggacgagc tgctcagggt gatgccttcc
841 tttgtcagca gcacctggga ggtgaagagg cctctgcgca agctgctccc tgaagtgaac
901 agtgaagcca tcgactttct ggagaagatc ctgaccttta accccatgga tcgcctaaca
961 gctgagatgg ggctgcaaca cccctacatg agcccatact cgtgccctga ggacgagccc
1021 acctcacaac accccttccg cattgaggat gagatcgacg acatcgtgct gatggccgct
1081 aaccagagcc agctgtccaa ctgggacacg tgcagttcca ggtaccctgt gagcctgtcg
1141 tcggacctgg agtggcggcc tgaccggtgc caggacgcca gcgaggtaca gcgcgacccg
1201 cgcgcgggtt cggcgccact ggctgaggac gtgcaggtgg acccgcgcaa ggactcgcac
1261 agcagctccg agcgcttcct agagcagtcg cactcgtcca tggagcgcgc cttcgaggcc
1321 gactacgggc gctcctgcga ctacaaggtg gggtcgccgt cctacctgga caagctgctg
1381 tggcgcgaca acaagccgca ccactactcg gagcccaagc tcatcctgga cctgtcgcac
1441 tggaagcagg cggccggcgc gccccccacg gccacggggc tggcggacac gggggcgcgc
1501 gaggacgagc cggccagcct cttcctggag atcgcgcagt gggtcaagag cacgcagggc
1561 ggcccagagc acgccagccc gcccgccgac gaccccgagc gccgcttgtc tgcctcgccc
1621 cccggccgcc cggccccggt ggacggcggc gccagccccc agttcgacct ggacgtgttc
1681 atctcccgcg ccctgaagct ctgcaccaag cccgaggacc tgccggacaa taaactgggc
1741 gacctcaatg gtgcgtgcat ccccgagcac cctggcgacc tcgtgcagac cgaggccttc
1801 tccaaagaaa ggtggtgagg gcggaggggc cgctccaggc cccacagagc aggagacccc
1861 cagagaaagc cggggctggc aggaggcggc cgcccttccc gcccctctct gctgccttgg
1921 ggttggcaga acacgtgaag gatccgagga gcgagaggaa tgtccatttc ttaaactgcc
1981 ttaataacta gcctttaacc tgtgggagcg g
//