LOCUS BC117129 3196 bp mRNA linear HUM 21-AUG-2007
DEFINITION Homo sapiens MMS19 nucleotide excision repair homolog (S.
cerevisiae), mRNA (cDNA clone MGC:150738 IMAGE:40125680), complete
cds.
ACCESSION BC117129
VERSION BC117129.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3196)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3196)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 6 Row: A Column: 17.
FEATURES Location/Qualifiers
source 1..3196
/db_xref="H-InvDB:HIT000387419"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:150738 IMAGE:40125680"
/tissue_type="Brain, cerebral cortex, PCR rescued clones"
/clone_lib="NIH_MGC_287"
/note="Vector: pCR4-TOPO with reversed insert; Clone
identification sequence tag: GTGTGGTT"
gene 1..3196
/gene="MMS19"
/gene_synonym="hMMS19"
/gene_synonym="MET18"
/db_xref="GeneID:64210"
/db_xref="HGNC:HGNC:13824"
CDS 24..3116
/gene="MMS19"
/gene_synonym="hMMS19"
/gene_synonym="MET18"
/codon_start=1
/product="MMS19 nucleotide excision repair homolog (S.
cerevisiae)"
/protein_id="AAI17130.1"
/db_xref="GeneID:64210"
/db_xref="HGNC:HGNC:13824"
/translation="MAAAAAVEAAAPMGALWGLVHDFVVGQQEGPADQVAADVKSGNY
TVLQVVEALGSSLENPEPRTRARGIQLLSQVLLHCHTLLLEKEVVHLILFYENRLKDH
HLVIPSVLQGLKALSLCVALPPGLAVSVLKAIFQEVHVQSLPQVDRHTVYNIITNFMR
TREEELKSLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISRDYSLGPFVEELFEVT
SCYFPIDFTPPPNDPHGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEVLSAKL
DSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERVEAEGLAALHSLTACLSR
SVLRADAEDLLDSFLSNILQDCRHHLCEPDMKLVWPSAKLLQAAAGASARACDSVTSN
VLPLLLEQFHKHSQSSQRRTILEMLLGFLKLQQKWSYEDKDQRPLNGFKDQLCSLVFM
ALTDPSTQLQLVGIRTLTVLGAQPDLLSYEDLELAVGHLYRLSFLKEDSQSCRVAALE
ASGTLAALYPVAFSSHLVPKLAEELRVGESNLTNGDEPTQCSRHLCCLQALSAVSTHP
SIVKETLPLLLQHLWQVNRGNMVAQSSDVIAVCQSLRQMAEKCQQDPESCWYFHQTAI
PCLLALAVQASMPEKEPSVLRKVLLEDEVLAAMVSVIGTATTHLSPELAAQSVTHIVP
LFLDGNVSFLPENSFPSRFQPFQDGSSGQRRLIALLMAFVCSLPRNVEIPQLNQLMRE
LLELSCCHSCPFSSTAAAKCFAGLLNKHPAGQQLDEFLQLAVDKVEAGLDSGPCRSQA
FTLLLWVTKALVLRYHPLSSCLTARLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAG
HAEVRIMFRQRFFTDNVPALVQGFHAAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTL
LSLLLEALSCPDCVVQLSTLSCLQPLLLEAPQVMSLHVDTLVTKFLNLSSSPSMAVRI
AALQCMHALTRLPTPVLLPYKPQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS
"
BASE COUNT 657 a 916 c 845 g 778 t
ORIGIN
1 tcccacggtc tctagttcgc gttatggccg ctgccgcggc tgtggaggcg gcggcgccta
61 tgggtgccct atggggcctc gtgcacgact tcgtcgtggg tcagcaagag ggccccgctg
121 accaggtggc tgcagatgtg aaatctggca actatacagt gttacaagtt gtggaagccc
181 ttgggtcctc tctagagaat ccagaacccc gaactcgggc acgaggaatc cagcttttgt
241 cacaggtgct actccactgt cacaccttgc tcctggagaa ggaagtggta cacctgatac
301 tgttctatga gaaccggctg aaggaccatc atcttgtgat cccatctgtc ctgcagggtt
361 tgaaggcact tagcctgtgt gtggccctgc ccccagggct ggctgtttct gtgcttaaag
421 ccatcttcca ggaagtgcat gtacagtccc tgccacaggt ggaccgacac acagtctaca
481 atatcatcac caattttatg cgaacccggg aagaagagct aaagagccta ggagctgact
541 tcacctttgg cttcatccag gtgatggatg gggaaaagga tccccgtaat cttctggtgg
601 ccttccgcat cgtccatgac ctcatctcca gggactatag cctgggaccc tttgtggagg
661 agttgtttga agtgacatcc tgttatttcc ctatcgattt tacccctcca cctaatgatc
721 cccatggtat ccagagagaa gacctcatcc tgagtcttcg cgctgtgctg gcttctacac
781 cacgatttgc tgagtttctg ctgcccctgt tgattgagaa agtggattct gaggttctga
841 gtgccaagtt ggattctcta cagactctga atgcttgctg tgctgtgtat ggacagaagg
901 aactgaagga cttcctcccc agcctttggg cttctatccg cagagaggtg ttccagacgg
961 caagtgagcg ggtggaggca gagggcctgg cggccctcca ctccctgact gcgtgtttgt
1021 ctcgctctgt gctgagggct gatgctgagg acctccttga ctccttcctt agcaacattc
1081 tacaggactg caggcaccac ctgtgtgaac cggacatgaa actggtgtgg cctagtgcca
1141 agctgttgca ggcagctgca ggtgcatctg cccgggcctg tgactctgtc accagcaatg
1201 tactgccttt actgctggaa cagttccaca agcacagtca gagcagccag cggcggacaa
1261 tccttgaaat gctcctgggt ttcttgaagc tgcagcagaa atggagctat gaagacaaag
1321 atcaaaggcc tctgaatggc ttcaaggacc agctgtgctc actggtattc atggctctaa
1381 cagaccccag cacccagctt cagcttgttg gcatccgtac actgacagtc ttgggtgccc
1441 agccagatct cctatcttat gaggacttgg agctggcagt gggtcacctg tacagactga
1501 gcttcctgaa ggaggattcc cagagttgca gggtggcagc actggaagca tcaggaaccc
1561 tggctgctct ctaccctgtg gccttcagca gccacctcgt acccaagctc gctgaggagc
1621 tgcgtgtagg ggagtcaaat ttgactaacg gagatgagcc cacccaatgc tcccggcatc
1681 tgtgctgtct gcaagccttg tcagctgtat caacacatcc cagcatcgtc aaggagacac
1741 tgcctctgct gctgcagcat ctctggcaag tgaacagagg gaatatggtt gcacaatcca
1801 gtgacgttat tgctgtctgt cagagcctca gacagatggc agaaaaatgt cagcaggacc
1861 ctgagagttg ctggtatttc caccagacag ctataccttg cctgcttgcc ttggctgtgc
1921 aggcctctat gccagagaag gagccctcag ttctgagaaa agtactattg gaggatgagg
1981 tgttggctgc catggtgtct gtcattggca ctgctacaac ccacctgagc cctgagttag
2041 ctgcccagag tgtgacacac attgtgcccc tcttcttgga tggcaacgtg tcctttctgc
2101 ctgaaaacag cttcccgagc agattccagc cattccagga tggctcctca gggcagaggc
2161 ggctgattgc actgcttatg gcctttgtct gctccctgcc tcgaaatgtg gaaatccctc
2221 agctgaacca actcatgcgg gagcttttgg aactgagctg ctgccacagc tgcccctttt
2281 cttccaccgc tgctgccaag tgctttgcag gactcctcaa caagcaccct gcagggcagc
2341 agctggatga attcctacag ctagctgtgg acaaagtgga ggctggcctg gactctgggc
2401 cctgtcgtag tcaggccttc actcttcttc tctgggtaac aaaggcccta gtgctcagat
2461 accatcctct cagctcctgc cttacagccc ggctcatggg cctcctgagt gacccagaat
2521 taggtccagc agcagctgat ggcttctctc tgctcatgtc tgactgcact gatgtgctga
2581 ctcgtgctgg ccatgccgaa gtgcggatca tgttccgcca gcggttcttc acagataatg
2641 tgcctgcttt ggtccagggc ttccatgctg ctccccaaga tgtgaagcca aactacttga
2701 agggtctttc tcatgtactt aacaggctgc ccaagcctgt actcttgcca gagctgccca
2761 cgcttctttc cttgctgctg gaggccctgt cctgccctga ctgtgtggtg cagctctcca
2821 ccctcagctg ccttcagcct cttctactgg aagcacccca agtcatgagt cttcacgtgg
2881 acaccctcgt caccaagttt ctgaacctca gctctagccc ttccatggct gtccggatcg
2941 ccgcactgca gtgcatgcat gctctcactc gcctgcccac ccctgtgctg ctgccgtaca
3001 aaccacaggt gattcgggcc ttagccaaac ccctggatga caagaagaga ctggtgcgca
3061 aggaagcagt gtcagccaga ggggagtggt ttctgttggg gagccctggc agctgagccc
3121 tcagtcctgg cctagactgt tctgacaatc taacctggga ttactaactg ttgagccatc
3181 ttccccaaag caggga
//