LOCUS BC115737 4939 bp mRNA linear HUM 29-JUN-2006
DEFINITION Homo sapiens UPF2 regulator of nonsense transcripts homolog
(yeast), mRNA (cDNA clone MGC:138834 IMAGE:40082728), complete cds.
ACCESSION BC115737
VERSION BC115737.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4939)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4939)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (14-APR-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 19 Row: n Column: 9.
FEATURES Location/Qualifiers
source 1..4939
/db_xref="H-InvDB:HIT000387391"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:138834 IMAGE:40082728"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: ATGGAAAA"
gene 1..4939
/gene="UPF2"
/gene_synonym="DKFZP434D222"
/gene_synonym="HUPF2"
/gene_synonym="KIAA1408"
/gene_synonym="RENT2"
/db_xref="GeneID:26019"
/db_xref="HGNC:HGNC:17854"
/db_xref="MIM:605529"
CDS 70..3888
/gene="UPF2"
/gene_synonym="DKFZP434D222"
/gene_synonym="HUPF2"
/gene_synonym="KIAA1408"
/gene_synonym="RENT2"
/codon_start=1
/product="UPF2 regulator of nonsense transcripts homolog
(yeast)"
/protein_id="AAI15738.1"
/db_xref="GeneID:26019"
/db_xref="HGNC:HGNC:17854"
/db_xref="MIM:605529"
/translation="MPAERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLT
AKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEER
KKQEEQAKRQQEEEAAAQMKEKEESIQLHQEAWERHHLRKELRSKNQNAPDSRPEENF
FSRLDSSLKKNTAFVKKLKTITEQQRDSLSHDFNGLNLSKYIAEAVASIVEAKLKISD
VNCAVHLCSLFHQRYADFAPSLLQVWKKHFEARKEEKTPNITKLRTDLRFIAELTIVG
IFTDKEGLSLIYEQLKNIINADRESHTHVSVVISFCRHCGDDIAGLVPRKVKSAAEKF
NLSFPPSEIISPEKQQPFQNLLKEYFTSLTKHLKRDHRELQNTERQNRRILHSKGELS
EDRHKQYEEFAMSYQKLLANSQSLADLLDENMPDLPQDKPTPEEHGPGIDIFTPGKPG
EYDLEGGIWEDEDARNFYENLIDLKAFVPAILFKDNEKSCQNKESNKDDTKEAKESKE
NKEVSSPDDLELELENLEINDDTLELEGGDEAEDLTKKLLDEQEQEDEEASTGSHLKL
IVDAFLQQLPNCVNRDLIDKAAMDFCMNMNTKANRKKLVRALFIVPRQRLDLLPFYAR
LVATLHPCMSDVAEDLCSMLRGDFRFHVRKKDQINIETKNKTVRFIGELTKFKMFTKN
DTLHCLKMLLSDFSHHHIEMACTLLETCGRFLFRSPESHLRTSVLLEQMMRKKQAMHL
DARYVTMVENAYYYCNPPPAEKTVKKKRPPLQEYVRKLLYKDLSKVTTEKVLRQMRKL
PWQDQEVKDYVICCMINIWNVKYNSIHCVANLLAGLVLYQEDVGIHVVDGVLEDIRLG
MEVNQPKFNQRRISSAKFLGELYNYRMVESAVIFRTLYSFTSFGVNPDGSPSSLDPPE
HLFRIRLVCTILDTCGQYFDRGSSKRKLDCFLVYFQRYVWWKKSLEVWTKDHPFPIDI
DYMISDTLELLRPKIKLCNSLEESIRQVQDLEREFLIKLGLVNDKDSKDSMTEGENLE
EDEEEEEGGAETEEQSGNESEVNEPEEEEGSDNDDDEGEEEEEENTDYLTDSNKENET
DEENTEVMIKGGGLKHVPCVEDEDFIQALDKMMLENLQQRSGESVKVHQLDVAIPLHL
KSQLRKGPPLGGGEGEAESADTMPFVMLTRKGNKQQFKILNVPMSSQLAANHWNQQQA
EQEERMRMKKLTLDINERQEQEDYQEMLQSLAQRPAPANTNRERRPRYQHPKGAPNAD
LIFKTGGRRR"
BASE COUNT 1695 a 893 c 1160 g 1191 t
ORIGIN
1 gctggagttg gtgctgggaa acccggggct aatgttgaca acaggctcga gattgtcctg
61 ggtcacataa tgccagctga gcgtaaaaag ccagcaagta tggaagaaaa agactcttta
121 ccaaacaaca aggaaaaaga ctgcagtgaa aggcggacag tgagcagcaa ggagaggcca
181 aaagacgata tcaagctcac tgccaagaag gaggtcagca aggcccctga agacaagaag
241 aagagactgg aagatgataa gagaaaaaag gaagacaagg aacgcaagaa aaaagacgaa
301 gaaaaggtga aggcagagga agaatcaaag aaaaaagaag aggaagaaaa aaagaaacat
361 caagaggaag agagaaagaa gcaagaagag caggccaaac gtcagcaaga agaagaagca
421 gctgctcaga tgaaagaaaa agaagaatcc attcagcttc atcaggaagc ttgggaacga
481 catcatttaa gaaaggaact tcgtagcaaa aaccaaaatg ctccggacag ccgaccagag
541 gaaaacttct tcagccgcct cgactcaagt ttgaagaaaa atactgcttt tgtcaagaaa
601 ctaaaaacta ttacagaaca acagagagac tccttgtccc atgattttaa tggcctaaat
661 ttaagcaaat acattgcaga agctgtagct tccatcgtgg aagcaaaact aaaaatctct
721 gatgtgaact gtgctgtgca cctctgctct ctctttcacc agcgttatgc tgactttgcc
781 ccatcacttc ttcaggtctg gaaaaaacat tttgaagcaa ggaaagagga gaaaacacct
841 aacatcacca agttaagaac tgatttgcgt tttattgcag aattgacaat agttgggatt
901 ttcactgaca aggaaggtct ttccttaatc tatgaacagc taaaaaatat tattaatgct
961 gatcgggagt cccacactca tgtctctgta gtgattagtt tctgtcgaca ttgtggagat
1021 gatattgctg gacttgtacc aaggaaagta aagagtgctg cagagaagtt taatttgagt
1081 tttcctccta gtgagataat tagtccagag aaacaacagc ccttccagaa tcttttaaaa
1141 gagtacttta cgtctttgac caaacacctg aaaagggacc acagggagct ccagaatact
1201 gagagacaaa acaggcgcat tctacattct aaaggggagc tcagtgaaga tagacataaa
1261 cagtatgagg aatttgctat gtcttaccag aagctgctgg caaattctca atccttagca
1321 gaccttttgg atgaaaatat gccagatctt cctcaagaca aaccaacacc agaagaacat
1381 gggcctggaa ttgatatatt cacacctggt aaacctggag aatatgactt ggaaggtggt
1441 atatgggaag atgaagatgc tcggaatttt tatgagaacc tcattgattt gaaggctttt
1501 gtcccagcca tcttgtttaa agacaatgaa aaaagttgtc agaataaaga gtccaacaaa
1561 gatgatacca aagaggcaaa agaatctaag gagaataagg aggtatcaag tcccgatgat
1621 ttggaacttg agttggagaa tctagaaatt aatgatgaca ccttagaatt agagggtgga
1681 gatgaagctg aagatcttac aaagaaactt cttgatgaac aagaacaaga agatgaggaa
1741 gccagcactg gatctcatct caagctcata gtagatgctt tcctacagca gttacccaac
1801 tgtgtcaacc gagatctgat agacaaggca gcaatggatt tttgcatgaa catgaacaca
1861 aaagcaaaca ggaagaagtt ggtacgggca ctcttcatag ttcctagaca aaggttggat
1921 ttgctaccat tttatgcaag attggttgct acattgcatc cctgcatgtc tgatgtagca
1981 gaggatcttt gttccatgct gaggggggat ttcagatttc atgtacggaa aaaggaccag
2041 atcaatattg aaacaaagaa taaaactgtt cgttttatag gagaactaac taagtttaag
2101 atgttcacca aaaatgacac actgcattgt ttaaagatgc ttctgtcaga cttctctcat
2161 caccatattg aaatggcatg caccctgctg gagacatgtg gacggtttct tttcagatct
2221 ccagaatctc acctgaggac cagtgtactt ttggagcaaa tgatgagaaa gaagcaagca
2281 atgcatcttg atgcgagata cgtcacaatg gtagagaatg catattacta ctgcaaccca
2341 cctccagctg aaaaaaccgt gaaaaagaaa cgtcctcctc tccaggaata tgtccggaaa
2401 cttttgtaca aggatctctc taaggttacc accgagaagg ttttgagaca gatgcgaaag
2461 ctgccctggc aggaccaaga agtgaaagac tatgttattt gttgtatgat aaacatctgg
2521 aatgtgaaat ataatagtat tcattgtgta gccaacctct tagcaggact agtgctctac
2581 caagaggatg ttgggatcca cgttgtggat ggagtgttag aagatattcg attaggaatg
2641 gaggttaatc aacctaaatt taatcagagg cgcatcagca gtgccaagtt cttaggagaa
2701 ctttacaatt accgaatggt ggaatcagct gttattttca gaactctgta ttcttttacc
2761 tcatttggtg ttaatcctga tggctctcca agttccctgg acccacctga gcatcttttc
2821 agaattagac tcgtatgcac tattctggac acatgtggcc agtactttga cagaggttcc
2881 agtaaacgaa aacttgattg tttccttgta tattttcagc gttatgtttg gtggaagaaa
2941 agtttggagg tttggacaaa agaccatcca tttcctattg atatagatta catgatcagt
3001 gatacactag aactgctaag accaaagatc aaactctgta attctctgga agaatccatc
3061 aggcaggtac aagacttgga acgagaattc ttaataaaac taggcctagt aaatgacaaa
3121 gactcaaaag attctatgac agaaggagaa aatcttgaag aggatgaaga agaagaagaa
3181 ggtggggctg aaacagaaga acaatctgga aatgaaagtg aagtaaatga gccagaagaa
3241 gaggagggtt ctgataatga tgatgatgag ggagaagaag aggaggaaga gaatacagat
3301 taccttacag attccaataa ggaaaatgaa accgatgaag agaatactga ggtaatgatt
3361 aaaggcggtg gacttaagca tgtaccttgt gtagaagatg aggacttcat tcaagctctg
3421 gataaaatga tgctagaaaa tctacagcaa cgaagtggtg aatctgttaa agtgcaccaa
3481 ctagatgttg ccattccttt gcatctcaaa agccagctga ggaaagggcc cccactggga
3541 ggtggggaag gagaggctga gtctgcagac acaatgccgt ttgtcatgtt aacaagaaaa
3601 ggcaataaac agcagtttaa gatccttaat gtacccatgt cctctcaact tgctgcaaat
3661 cactggaacc agcaacaggc agaacaagaa gagaggatga gaatgaaaaa gctcacacta
3721 gatatcaatg aacggcaaga acaagaagat tatcaagaaa tgttgcagtc tcttgcacag
3781 cgcccagctc cagcaaacac caatcgtgag aggcggcctc gctaccaaca tccgaaggga
3841 gcacctaatg cagatctaat ctttaagact ggtgggagga gacgttgatc cagcagcacg
3901 tgtcatttca ttaggtcctg tatctgatgt tgtggttagt ggagtcctcc agcaattgaa
3961 tgagagcagt ggacacatct cagcaggtcg gtctagagag ttgcgaatct aaacctggga
4021 caggctgggg ccaggaggca gaaacaccag cctctgccaa caccggaaca agccgacgct
4081 tccagacaag gcggaaaagg ccttttgtaa tggaaatctc gcgagggtta atcttctctt
4141 gagaatggca gtcaagaaat gagatggttc acttgactac tgagcagtta caccaaggag
4201 agcgtgaagg agatgattga gccagagaag aaacgggttg tgatggtaat ggtgtggggg
4261 aaatgaactt gagctttaaa cttgatttga gtttcagtgt ctctgaattg aacatcccac
4321 gttggaagaa gatacatttg ggggctccag gactacagta gaaaagtata gagcaagcag
4381 gaaaatcttc tagtaaaact tacatgcagg acaacaaaat gatgaaagat atccaaatac
4441 cagataatcc accaggaagg cttttgttta ggaatttgtt tcaagaggaa caagggatga
4501 gggagaaaaa tccgttttat ccatcagagt cagtgctata aaattgccta ttaaggtaaa
4561 agaaaaatgt ggagactatt ttactataca gagagcatta attcagatgg cttagaaaag
4621 tgataccagc ccaagaacag ggatctaggt gagcccattg taagtatcat tgaaaacaaa
4681 acatgcccgt caacatgtca cagaaaacga acgaaggaca acaagaagtg gatgagaata
4741 ttttgttgac cttcatgggt ttacagcctc tgtctctaaa caaagtatgg aaacaagtag
4801 agcttttatt ttgcttttgt ttttgttttg tttttttttt gttttccccc actaaataga
4861 aatgagggtc cttagtctgt ttctgacaat ctgttaattt cttaggacag ctgtctttgg
4921 tttgctttcc agcaggcgt
//