LOCUS BC114950 1928 bp mRNA linear HUM 19-MAR-2009
DEFINITION Homo sapiens dachshund homolog 2 (Drosophila), mRNA (cDNA clone
MGC:138545 IMAGE:40006598), complete cds.
ACCESSION BC114950
VERSION BC114950.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1928)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1928)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (13-APR-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 19 Row: b Column: 14
The stop codon of the CDS annotated on this record is located > 55
bases upstream of a splice junction, and therefore the mRNA is
predicted to be subject to nonsense-mediated mRNA decay (NMD).
FEATURES Location/Qualifiers
source 1..1928
/db_xref="H-InvDB:HIT000340773"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:138545 IMAGE:40006598"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: TTTTGTC"
gene 1..1928
/gene="DACH2"
/db_xref="GeneID:117154"
/db_xref="HGNC:HGNC:16814"
/db_xref="MIM:300608"
CDS 482..1879
/gene="DACH2"
/codon_start=1
/product="DACH2 protein"
/protein_id="AAI14951.1"
/db_xref="GeneID:117154"
/db_xref="HGNC:HGNC:16814"
/db_xref="MIM:300608"
/translation="MPEFRSVAQAAVQWCDLGSLQLPPPRFKGFLCLSLPSSWNYSSR
PGRPPKRSLGVLQENARLLTHAVPGLLSPGLITPTGITAAAMAEAMKLQKMKLMAMNT
LQGNGSQNGTESEPDDLNSNTGGSESSWDKDKMQSPFAAPGPQHGIAHAALAGQPGIG
GAPTLNPLQQNHLLTNRLDLPFMMMPHPLLPVSLPPASVAMAMNQMNHLNTIANMAAA
AQIHSPLSRAGTSVIKERIPESPSPAPSLEENHRPGSQTSSHTSSSVSSSPSQMDHHL
ERMEEVPVQIPIMKSPLDKIQLTPGQALPAGFPGPFIFADSLSSVETLLTNIQGLLKV
ALDNARIQEKQIQQEKKELRLELYREREIRENLERQLAVELQSRTTMQKRLKKEKKTK
RKLQEALEFESKRREQVEQALKQATTSDSGLRMLKDTGIPDIEIENNGTPHDSAAMQG
GNYYCLEMAQQLYSA"
BASE COUNT 508 a 503 c 477 g 440 t
ORIGIN
1 atggctgtct ccgcatctcc agtgatctct gcaacttcca gcggcgccgg cgtcccgggg
61 ggcttattcc gggccgaacc cctgtactcg actcccagag agccccctcg tcttactcct
121 aatatgatca atagtttcgt ggttaataac cacagcaaca gtgccggagg cggcggcagg
181 ggcaacacca acaccaacga gtgccgcatg gtcgacatgc acgggatgaa ggtggcttcg
241 ttcctgatgg acggccagga actgatctgc ctgccgcaag tctttgatct ttttctcaag
301 cacctggtgg gaggcttgca cactgtgtac accaagctga agagactgga tatatccccc
361 gtggtgtgta ctgttgagca ggtccggatc ctccgcgggc tgggggccat ccagcccggg
421 gtaaaccgct gcaaactcat caccaggaaa gacttcgaaa ctttgttcac cgattgcacc
481 aatgccagag tttcgctctg ttgcccaggc tgcagtgcag tggtgtgatc ttggctcgct
541 gcaacttccg cctcccaggt tcaagggatt cttgtgcctc agcctcccga gtagctggaa
601 ttacagttca agacccggca ggccccctaa gcgttctttg ggagtgttgc aggaaaatgc
661 ccgccttctg acccatgcag tcccaggcct cttatcgcca ggacttatca ctccgacagg
721 tataacagct gcagcgatgg ctgaggcgat gaaacttcag aagatgaagc ttatggctat
781 gaacactctt cagggaaatg gaagccaaaa tgggaccgaa tcagagcctg atgatcttaa
841 ttctaacaca ggtggaagtg aatcctcctg ggataaagat aagatgcagt ctccatttgc
901 tgcacctgga ccccaacatg gaattgctca tgcagcccta gctggccagc caggcattgg
961 gggtgctcca accctcaatc cactgcagca gaaccacctg ctaaccaata gactggatct
1021 gccatttatg atgatgcctc atcccctact tccagtcagc ttacctcctg catcagttgc
1081 catggcaatg aatcagatga accatctcaa tactattgcc aacatggctg ctgcagcaca
1141 gattcacagt ccactctcca gagctggtac ctctgttata aaggagcgga tcccagagag
1201 tccttctcct gctccttctc tagaagagaa tcatcgtcct gggagccaga cctcttccca
1261 caccagcagc agtgtgtcca gctctccctc tcagatggat catcatttgg aaagaatgga
1321 agaggtacca gttcaaattc caataatgaa gtcacccttg gacaagatac agctgactcc
1381 tgggcaggca ttgcccgctg gattccctgg accattcatt tttgctgata gtctgtcctc
1441 cgtggagact ctgttgacca acattcaggg tctgctgaaa gttgctttgg ataatgctcg
1501 catccaggag aagcagattc aacaagaaaa gaaggagctg cgactggagc tctatagaga
1561 gagagaaatt agagaaaacc ttgaaagaca acttgcagtt gagcttcaaa gcagaactac
1621 tatgcaaaag cgcctgaaga aggagaaaaa aaccaagaga aaattgcagg aagccttgga
1681 atttgaatca aagcgccggg agcaagtgga gcaggcactt aagcaagcca ccactagtga
1741 cagtggcctg aggatgttaa aagatactgg aattccagat attgaaatag aaaacaatgg
1801 gactcctcat gatagtgctg ctatgcaagg aggtaactat tactgtttag aaatggcaca
1861 acagttgtat tcagcctgaa aggtcctcgc tggctttaca taaatgaaga tgcttgtgat
1921 tccagtta
//