LOCUS BC114622 4247 bp mRNA linear HUM 29-JUN-2006
DEFINITION Homo sapiens frizzled homolog 4 (Drosophila), mRNA (cDNA clone
MGC:138777 IMAGE:40082091), complete cds.
ACCESSION BC114622
VERSION BC114622.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 4247)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 4247)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-MAR-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 19 Row: l Column: 3.
FEATURES Location/Qualifiers
source 1..4247
/db_xref="H-InvDB:HIT000387286"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:138777 IMAGE:40082091"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: AGTGTTCC"
gene 1..4247
/gene="FZD4"
/gene_synonym="FEVR"
/gene_synonym="Fz-4"
/gene_synonym="FZD4S"
/gene_synonym="FzE4"
/gene_synonym="GPCR"
/gene_synonym="MGC34390"
/db_xref="GeneID:8322"
/db_xref="HGNC:HGNC:4042"
/db_xref="MIM:604579"
CDS 175..1788
/gene="FZD4"
/gene_synonym="FEVR"
/gene_synonym="Fz-4"
/gene_synonym="FZD4S"
/gene_synonym="FzE4"
/gene_synonym="GPCR"
/gene_synonym="MGC34390"
/codon_start=1
/product="frizzled homolog 4 (Drosophila)"
/protein_id="AAI14623.1"
/db_xref="GeneID:8322"
/db_xref="HGNC:HGNC:4042"
/db_xref="MIM:604579"
/translation="MAWRGAGPSVPGAPGGVGLSLGLLLQLLLLLGPARGFGDEEERR
CDPIRISMCQNLGYNVTKMPNLVGHELQTDAELQLTTFTPLIQYGCSSQLQFFLCSVY
VPMCTEKINIPIGPCGGMCLSVKRRCEPVLKEFGFAWPESLNCSKFPPQNDHNHMCME
GPGDEEVPLPHKTPIQPGEECHSVGTNSDQYIWVKRSLNCVLKCGYDAGLYSRSAKEF
TDIWMAVWASLCFISTAFTVLTFLIDSSRFSYPERPIIFLSMCYNIYSIAYIVRLTVG
RERISCDFEEAAEPVLIQEGLKNTGCAIIFLLMYFFGMASSIWWVILTLTWFLAAGLK
WGHEAIEMHSSYFHIAAWAIPAVKTIVILIMRLVDADELTGLCYVGNQNLDALTGFVV
APLFTYLVIGTLFIAAGLVALFKIRSNLQKDGTKTDKLERLMVKIGVFSVLYTVPATC
VIACYFYEISNWALFRYSADDSNMAVEMLKIFMSLLVGITSGMWIWSAKTLHTWQKCS
NRLVNSGKVKREKRGNGWVKPGKGSETVV"
BASE COUNT 1073 a 933 c 1017 g 1224 t
ORIGIN
1 aatcccacac agtcgcgcgc agctgctgga gagccggccg ctgccccctc gtcgccgcat
61 cacactcccg tcccgggagc tgggagcagc gcgggcagcc ggcgcccccg tgcaaactgg
121 gggtgtctgc cagagcagcc ccagccgttg ccgctgctac ccccgatgct ggccatggcc
181 tggcggggcg cagggccgag cgtcccgggg gcgcccgggg gcgtcggtct cagtctgggg
241 ttgctcctgc agttgctgct gctcctgggg ccggcgcggg gcttcgggga cgaggaagag
301 cggcgctgcg accccatccg catctccatg tgccagaacc tcggctacaa cgtgaccaag
361 atgcccaacc tggttgggca cgagctgcag acggacgccg agctgcagct gacaactttc
421 acaccgctca tccagtacgg ctgctccagc cagctgcagt tcttcctttg ttctgtttat
481 gtgccaatgt gcacagagaa gatcaacatc cccattggcc catgcggcgg catgtgtctt
541 tcagtcaaga gacgctgtga acccgtcctg aaggaatttg gatttgcctg gccagagagt
601 ctgaactgca gcaaattccc accacagaac gaccacaacc acatgtgcat ggaagggcca
661 ggtgatgaag aggtgccctt acctcacaaa acccccatcc agcctgggga agagtgtcac
721 tctgtgggaa ccaattctga tcagtacatc tgggtgaaaa ggagcctgaa ctgtgtgctc
781 aagtgtggct atgatgctgg cttatacagc cgctcagcca aggagttcac tgatatctgg
841 atggctgtgt gggccagcct gtgtttcatc tccactgcct tcacagtact gaccttcctg
901 atcgattctt ctaggttttc ctaccctgag cgccccatca tatttctcag tatgtgctat
961 aatatttata gcattgctta tattgtcagg ctgactgtag gccgggaaag gatatcctgt
1021 gattttgaag aggcagcaga acctgttctc atccaagaag gacttaagaa cacaggatgt
1081 gcaataattt tcttgctgat gtactttttt ggaatggcca gctccatttg gtgggttatt
1141 ctgacactca cttggttttt ggcagcagga ctcaaatggg gtcatgaagc cattgaaatg
1201 cacagctctt atttccacat tgcagcctgg gccatccccg cagtgaaaac cattgtcatc
1261 ttgattatga gactggtgga tgcagatgaa ctgactggct tgtgctatgt tggaaaccaa
1321 aatctcgatg ccctcaccgg gttcgtggtg gctcccctct ttacttattt ggtcattgga
1381 actttgttca ttgctgcagg tttggtggcc ttgttcaaaa ttcggtcaaa tcttcaaaag
1441 gatgggacaa agacagacaa gttagaaaga ctgatggtca agattggggt gttctcagta
1501 ctgtacacag ttcctgcaac gtgtgtgatt gcctgttatt tttatgaaat ctccaactgg
1561 gcactttttc ggtattctgc agatgattcc aacatggctg ttgaaatgtt gaaaattttt
1621 atgtctttgt tggtgggcat cacttcaggc atgtggattt ggtctgccaa aactcttcac
1681 acgtggcaga agtgttccaa cagattggtg aattctggaa aggtaaagag agagaagaga
1741 ggaaatggtt gggtgaagcc tggaaaaggc agtgagactg tggtataagg ctagtcagcc
1801 tccatgcttt cttcattttg aaggggggaa tgccagcatt ttggaggaaa ttctactaaa
1861 agttttatgc agtgaatctc agtttgaaca aactagcaac aattaagtga cccccgtcaa
1921 cccactgcct cccaccccga ccccagcatc aaaaaaccaa tgattttgct gcagactttg
1981 gaatgatcca aaatggaaaa gccagttaga ggctttcaaa gctgtgaaaa atcaaaacgt
2041 tgatcacttt agcaggttgc agcttggagc gtggaggtcc tgcctagatt ccaggaagtc
2101 cagggcgata ctgttttccc ctgcagggtg ggatttgagc tgtgagttgg taactagcag
2161 ggagaaatat taactttttt aaccctttac cattttaaat actaactggg tctttcagat
2221 agcaaagcaa tctataaaca ctggaaacgc tgggttcaga aaagtgttac aagagtttta
2281 tagtttggct gatgtaacat aaacatcttc tgtggtgcgc tgtctgctgt ttagaacttt
2341 gtggactgca ctcccaagaa gtggtgttag aatctttcag tgcctttgtc ataaaacagt
2401 tatttgaaca aacaaaagta ctgtactcac acacataagg tatccagtgg atttttcttc
2461 tctgtcttcc tctcttaaat ttcaacatct ctcttcttgg ctgctgctgt tttcttcatt
2521 ttatgttaat gactcaaaaa aggtattttt atagaatttt tgtactgcag catgcttaaa
2581 gaggggaaaa ggaagggtga ttcactttct gacaatcact taattcagag gaaaatgaga
2641 tttactaagt tgacttacct gacggacccc agagacctat tgcattgagc agtggggact
2701 taatatattt tacttgtgtg attgcatcta tgcagacgcc agtctggaag agctgaaatg
2761 ttaagtttct tggcaacttt gcattcacac agattagctg tgtaattttt gtgtgtcaat
2821 tacaattaaa agcacattgt tggaccatga catagtatac tcaactgact ttaaaactat
2881 ggtcaacttc aacttgcatt ctcagaatga tagtgccttt aaaaattttt ttatttttta
2941 aagcataaga atgttatcag aatctggtct acttaggaca atggagactt tttcagtttt
3001 ataaagggaa ctgaggacag ctaatccaac tacttggtgc gtaattgttt cctagtaatt
3061 ggcaaaggct ccttgtaaga tttcattgga ggcagtgtgg cctggagtat ttatatggtg
3121 cttaatgaat ctccagaatg ccagccagaa gcctgattgg ttagtaggga ataaagtgta
3181 gaccatatga aatgaactgc aaactctaat agcccaggtc ttaattgcct ttagcagagg
3241 tatccaaagc ttttaaaatt tatgcatacg ttcttcacaa gggggtaccc ccagcagcct
3301 ctcgaaaatt gcacttctct taaaactgta actggccttt ctcttacctt gccttaggcc
3361 ttctaatcat gagatcttgg ggacaaattg actatgtcac aggttgctct ccttgtaact
3421 catacctgtc tgcttcagca actgctttgc aatgacattt atttattaat tcatgcctta
3481 aaaaaatagg aagggaagct tttttttttc tttttttttt ttcaatcaca ctttgtggaa
3541 aaacatttcc agggactcaa aattccaaaa aggtggtcaa attctggaag taagcatttc
3601 ctctttttta aaaatttggt ttgagcctta tgcccatagt ttgacatttc cctttcttct
3661 ttcctttttg tttttgtgtg gttcttgagc tctctgacat caagatgcat gtaaagtcga
3721 ttgtatgttt tggaaggcaa agtcttggct tttgagactg aagttaagtg ggcacaggtg
3781 gcccctgctg ctgtgcccag tctgagtacc ttggctagac tctaggtcag gctccaggag
3841 catgagaatt gatccccaga agaaccattt taactccatc tgatactcca ttgcctatga
3901 aatgtaaaat gtgaactccc tgtgctgctt gtagacagtt cccataactg tccacggccc
3961 tggagcacgc acccaggggc agagcctgcc cttactcacg ctctgctctg gtgtcttggg
4021 agttgtgcag ggactctggc ccaggcaggg gaaggaagac caggcggtag gggactggtc
4081 ttgctgttag agtatagagg tttgtaatgc agttttcttc ataatgtgtc agtgattgtg
4141 tgaccaaggc agcatctagc agaaagccag gcatggagta ggtgatcgat acttgtcaat
4201 gactaaataa taacaataaa agagcacttg ggtgaatctg ggcacct
//