LOCUS BC114620 5435 bp mRNA linear HUM 08-DEC-2006
DEFINITION Homo sapiens periplakin, mRNA (cDNA clone MGC:134872
IMAGE:40070172), complete cds.
ACCESSION BC114620
VERSION BC114620.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5435)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5435)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-MAR-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Sequencing Group at the Stanford Human Genome
Center, Stanford University School of Medicine, Stanford, CA 94305
Web site: http://www-shgc.stanford.edu
Contact: (Dickson, Mark) mcd@paxil.stanford.edu
Dickson, M., Schmutz, J., Grimwood, J., Rodriquez, A., and Myers,
R. M.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCG Plate: 2 Row: h Column: 10.
FEATURES Location/Qualifiers
source 1..5435
/db_xref="H-InvDB:HIT000387285"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:134872 IMAGE:40070172"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: AGTATGCC"
gene 1..5435
/gene="PPL"
/gene_synonym="KIAA0568"
/db_xref="GeneID:5493"
/db_xref="HGNC:HGNC:9273"
/db_xref="MIM:602871"
CDS 51..5321
/gene="PPL"
/gene_synonym="KIAA0568"
/codon_start=1
/product="periplakin"
/protein_id="AAI14621.1"
/db_xref="GeneID:5493"
/db_xref="HGNC:HGNC:9273"
/db_xref="MIM:602871"
/translation="MNSLFRKRNKGKYSPTVQTRSISNKELSELIEQLQKNADQVEKN
IVDTEAKMQSDLARLQEGRQPEHRDVTLQKVLDSEKLLYVLEADAAIAKHMKHPQGDM
IAEDIRQLKERVTNLRGKHKQIYRLAVKEVDPQVNWAALVEEKLDKLNNQSFGTDLPL
VDHQVEEHNIFHNEVKAIGPHLAKDGDKEQNSELRAKYQKLLAASQARQQHLSSLQDY
MQRCTNELYWLDQQAKGRMQYDWSDRNLDYPSRRRQYENFINRNLEAKEERINKLHSE
GDQLLAAEHPGRNSIEAHMEAVHADWKEYLNLLICEESHLKYMEDYHQFHEDVKDAQE
LLRKVDSDLNQKYGPDFKDRYQIELLLRELDDQEKVLDKYEDVVQGLQKRGQQVVPLK
YRRETPLKPIPVEALCDFEGEQGLISRGYSYTLQKNNGESWELMDSAGNKLIAPAVCF
VIPPTDPEALALADSLGSQYRSVRQKAAGSKRTLQQRYEVLKTENPGDASDLQGRQLL
AGLDKVASDLDRQEKAITGILRPPLEQGRAVQDSAERAKDLKNITNELLRIEPEKTRS
TAEGEAFIQALPGSGTTPLLRTQVEDTNRKYEHLLQLLDLAQEKVDVANRLEKSLQQS
WELLATHENHLNQDDTVPESSRVLDSKGQELAAMACELQAQKSLLGEVEQNLQAAKQC
SSTLASRFQEHCPDLERQEAEVHKLGQRFNNLRQQVERRAQSLQSAKAAYEHFHRGHD
HVLQFLVSIPSYEPQETDSLSQMETKLKNQKNLLDEIASREQEVQKICANSQQYQQAV
KDYELEAEKLRSLLDLENGRSSHVSKRARLQSPATKVKEEEAALAAKFTEVYAINRQR
LQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELDEETERRRQLENEVK
STQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEEQHKNQLLQEELE
ALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEALRRQKGAREAE
VLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQDQLREKQE
EELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDEAAKARA
SQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQERKYRG
AEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTRLI
ERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQK
KQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVE
LRQIDKLRAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAE
AREKVTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAE
VKEKVVLSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNS
KSSKELDFLREENHKLQLERENLQLETRRLQSEINMAATETRDLRNMTVADSGTNHDS
RLWSLERELDDLKRLSKDKDLEIDELQKRLGSVAVKREQRENHLRRSIVVIHPDTGRE
LSPEEAHRAGLIDWNMFVKLRSQECDWEEISVKGPNGESSVIHDRKSGKKFSIEEALQ
SGRLTPAQYDRYVNKDMSIQELAVLVSGQK"
BASE COUNT 1395 a 1444 c 1858 g 738 t
ORIGIN
1 ggtgcgcgcc cggcccgcca gccgccgccg cccgcacccc gagcgccacc atgaactcgc
61 tcttcaggaa gagaaacaaa ggcaaataca gccccactgt gcagacccgg agcatctcta
121 acaaggagct ctcggagctg atcgagcagc tgcagaagaa tgccgaccag gtggagaaga
181 acatcgtgga cacagaggcc aagatgcaga gtgacctggc tcggctgcag gagggtcggc
241 agcctgagca ccgggacgtg accctgcaga aggtgttgga ctctgagaag ctgctctatg
301 tgctagaggc ggatgcggcc attgccaagc acatgaagca cccacagggg gacatgatcg
361 ccgaggatat ccgccagctg aaggagcgtg tgaccaacct gcgcgggaaa cacaagcaga
421 tctacaggct ggcggtgaag gaagtggatc cacaggtcaa ctgggcggca ctggtggagg
481 agaagctgga caagctgaac aaccagagct ttgggactga cctgccgctg gtggaccacc
541 aagtggagga gcataacatc ttccacaatg aggtcaaggc catcgggccc cacctggcca
601 aggacgggga caaggagcag aacagcgaac tccgggccaa gtaccagaaa ctgctggcag
661 catcacaggc ccggcagcag cacctgagtt cgctgcagga ctacatgcag cgctgcacca
721 atgagctgta ctggctggac cagcaggcca agggccgcat gcagtacgac tggagtgacc
781 gcaacctcga ctaccccagc cgccggcgcc agtatgagaa tttcatcaac cggaacctgg
841 aggccaaaga ggagagaatc aacaaactgc acagcgaggg cgaccagctg ctggcggccg
901 agcaccccgg gaggaactcc attgaggcgc acatggaggc tgtgcacgca gactggaagg
961 agtacctgaa cctgctcatc tgcgaggaga gccacctcaa gtacatggag gactaccacc
1021 agtttcacga agacgtgaag gacgctcagg agctgctgcg caaggtggac tcggacctga
1081 accagaagta tggccctgac ttcaaggacc ggtaccagat tgagctgctg ctgcgggagc
1141 tggatgacca ggagaaggtg ctggacaagt atgaggacgt ggtgcagggg ctgcagaagc
1201 gaggccagca ggtggtgccc ctcaagtacc gccgggagac tccgctcaag cccatccccg
1261 tggaggcact ctgtgacttt gagggggagc agggcctgat ctcgcggggc tacagctaca
1321 ccctgcagaa gaacaacggg gagagctggg agctcatgga cagcgctggg aacaagctga
1381 ttgctccggc cgtctgtttt gtgatccccc ccacagaccc tgaggccctg gctctggctg
1441 acagcctggg cagccagtac cggagcgtgc ggcagaaggc agctgggagc aaacgcacgc
1501 tgcagcagcg gtatgaggtg ctgaagaccg agaatcccgg agatgcctct gacctacagg
1561 ggcggcagct gctggctggc ttggacaagg tggccagcga cctggaccgg caggagaagg
1621 ccatcacagg gatcctgcgg ccaccactgg agcaaggccg ggctgtgcag gacagtgccg
1681 agcgggccaa ggacctcaag aacatcacca acgagctact gcggattgaa cctgagaaga
1741 cgcggagcac ggctgagggc gaagccttca tccaggccct cccaggcagt ggcaccacac
1801 ccctgctgag gacccaggtg gaggacacca accggaaata cgagcacctc ctgcagctgc
1861 tggacttggc ccaggagaag gttgatgtgg ccaaccgcct ggagaagagc ctgcagcaga
1921 gctgggagtt gctggccaca cacgagaacc atctgaatca ggatgacaca gtgcctgaga
1981 gcagccgtgt cctggacagc aaggggcagg agctggcggc catggcctgt gagttacagg
2041 cccagaagtc cctcctgggt gaggtggagc agaacttgca ggcggccaag cagtgctcga
2101 gcacactggc cagccgcttc caggagcact gcccggacct ggagcgccag gaggccgagg
2161 tgcacaagct gggccagcgt ttcaacaacc tgcgccagca ggtggaacgc agggcgcaga
2221 gcctacagag cgccaaggca gcctacgagc acttccaccg cggccatgac cacgtgctgc
2281 agttcctagt cagcatcccc agttacgagc cccaggagac agacagcctc agccagatgg
2341 agaccaagct gaagaaccag aagaacctgc tagatgagat agcaagtagg gagcaggaag
2401 tacagaagat ctgtgccaat tcccagcagt accagcaagc tgtaaaggac tatgagttag
2461 aagcagaaaa actaaggtct cttctcgact tggagaatgg aaggagcagc cacgtgagca
2521 agagagccag gctccaatct cctgccacca aagtgaagga agaggaagca gcacttgccg
2581 ccaagttcac tgaagtttat gccatcaaca gacagaggct gcagaatctg gagtttgctc
2641 tgaatctcct cagacagcag ccggaagtag aagtgaccca tgagaccctg caaaggaata
2701 ggccggactc tggagtggag gaggcgtgga agatcaggaa ggaactggat gaggagactg
2761 agcggaggcg gcagctggag aacgaggtca agagcaccca ggaagaaatc tggaccttga
2821 ggaatcaggg gcctcaggaa tcggtggtga ggaaggaggt gctcaagaag gtgccggatc
2881 ccgtgctgga ggagagcttc cagcagctgc agcggacgct ggcagaggag cagcacaaga
2941 accagctgct gcaggaggag ctggaggcac tgcagctgca gctgcgtgcc ctggagcagg
3001 agaccagaga cggggggcag gagtacgtgg tcaaggaggt cctgcgcatc gagcctgaca
3061 gggcccaggc ggatgaggtc ttgcagctgc gggaggagct ggaggcactg aggcggcaga
3121 agggcgcccg ggaggcagag gtgctcctcc tgcagcagcg tgtggccgcc ctggctgaag
3181 agaagagccg ggcgcaggag aaggtcacag agaaagaggt ggtgaaactg cagaatgacc
3241 cccagctgga ggcagagtac cagcagctgc aggaggacca ccagcgccag gaccagctca
3301 gggagaagca ggaggaggag ctgagcttcc tccaggacaa gctcaagagg ctagagaagg
3361 agcgggccat ggccgagggc aagatcaccg tcaaggaggt gctcaaggtg gagaaggacg
3421 cggccaccga gagggaggtc agcgatctca cccgccaata tgaggacgag gctgccaagg
3481 ctcgcgctag ccagagggag aagacggagc tgctccgaaa gatatgggcc ttggaggagg
3541 agaacgccaa agtggtggtg caggagaagg tgcgggagat cgtgcggcca gaccccaagg
3601 cggaaagtga agtggcgaac ctccgcctgg agcttgtgga gcaggagcga aagtaccggg
3661 gtgccgagga gcagctccgg agctaccaga gtgagctgga ggccctcagg aggcgaggcc
3721 cccaggtgga agtcaaagag gtgactaagg aagtcattaa gtacaagact gaccctgaga
3781 tggagaagga gcttcagcgg ctcagggagg agatcgtgga caagaccaga ctgatcgaaa
3841 ggtgtgattt agagatctac cagctgaaaa aggaaatcca ggccctgaaa gacaccaaac
3901 cccaggtcca gaccaaagag gtggtccagg agatcctcca attccaagaa gaccctcaaa
3961 ccaaggagga ggtggcgtct ctgagggcaa agctctcaga ggagcagaag aaacaagtgg
4021 atctggagag ggaaagagct tcccaggaag agcagatcgc ccggaaagag gaggagctct
4081 cgcgggtgaa ggaaagggtg gtgcagcagg aggtggtcag gtatgaggag gagccaggcc
4141 tccgggccga ggcgagtgcc tttgccgaga gcatcgatgt ggagctgcgg cagattgaca
4201 agctgcgggc agagctgcgg cggctgcagc gccggcgcac cgagcttgag cggcagctgg
4261 aggagctaga gcgcgagcgg caggcccgca gggaggccga gcgcgaggta cagcggttgc
4321 agcagcggct ggcagcgctg gagcaggaag aagctgaggc ccgtgagaag gtaacccata
4381 cgcagaaggt ggtgctgcag caggacccgc agcaggcgcg agagcatgcc ctgctccgac
4441 tccagctgga agaagagcag caccggcggc agctcctgga gggggagctc gagaccctcc
4501 ggaggaaact ggctgcactg gagaaggcgg aggtcaagga gaaggtggtg ctctccgaga
4561 gtgtccaggt ggagaagggc gacaccgagc aagagatcca gaggctcaag agcagcctgg
4621 aggaggagag ccgcagcaag cgcgagctgg acgtcgaggt gagccggctg gaagccaggc
4681 tttcggagct ggaattccat aactccaagt catccaagga actagacttt ctgagggaag
4741 agaaccacaa attacagctg gagagggaaa acctgcagct ggagacccga aggctccaat
4801 cggaaatcaa catggcagcg acggaaacac gagacctgcg gaacatgacc gtggcggact
4861 ctgggaccaa ccatgactcc agactgtggt ccctggagag ggaactggat gacctcaaga
4921 ggctctccaa ggacaaagac ctcgagatcg acgagctgca gaagcgcctg ggctccgtgg
4981 ccgtcaagcg ggagcagcgg gagaaccacc tgcggcgctc catcgtagtc atccaccctg
5041 acacaggccg cgagctgtcc ccggaggaag cccaccgtgc cgggctcatt gactggaaca
5101 tgttcgtgaa actcagaagc caggagtgcg actgggagga gatctcagtg aagggtccca
5161 atggggagtc ctcagtgata cacgacagga agtctggcaa gaagttctcc atcgaagagg
5221 ccctgcagag tggcaggctg acccctgctc agtatgaccg ctatgtcaac aaggatatgt
5281 ccatccagga gctggcggtc ttggtatctg ggcagaagta ggcacagctc ttgcaactct
5341 tcgtaacggc agacgctggc cctctcctac gacgcagtga cctccttggt gtcgtcctct
5401 ccctagccct ggtgcaggcc aagcatttta tacat
//