LOCUS BC114475 1647 bp mRNA linear HUM 18-AUG-2006
DEFINITION Homo sapiens apolipoprotein L, 1, mRNA (cDNA clone IMAGE:40034501),
partial cds.
ACCESSION BC114475
VERSION BC114475.1
KEYWORDS .
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 1647)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 1647)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (10-MAR-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 19 Row: g Column: 20.
FEATURES Location/Qualifiers
source 1..1647
/db_xref="H-InvDB:HIT000340702"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="IMAGE:40034501"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: TATGAAAC"
gene <1..1647
/gene="APOL1"
/gene_synonym="APO-L"
/gene_synonym="APOL-I"
/db_xref="GeneID:8542"
/db_xref="HGNC:HGNC:618"
/db_xref="MIM:603743"
CDS <1..1295
/gene="APOL1"
/gene_synonym="APO-L"
/gene_synonym="APOL-I"
/codon_start=3
/product="APOL1 protein"
/protein_id="AAI14476.1"
/db_xref="GeneID:8542"
/db_xref="HGNC:HGNC:618"
/db_xref="MIM:603743"
/translation="RITGGGIHTAQNSWILLSLCQGKIPWRRPCSDMEGAALLRVSVL
CIWMSALFLGVGVRAEEAGARVQQNVPSGTDTGDPQSKPLGDWAAGTMDPESSIFIED
AIKYFKEKVSTQNLLLLLTDNEAWNGFVAAAELPRNEADELRKALDNLARQMIMKDKN
WHDKGQQYRNWFLKEFPRLKSKLEDNIRRLRALADGVQKVHKGTTIANVVSGSLSISS
GILTLVGMGLAPFTEGGSLVLLEPGMELGITAALTGITSSTIDYGKKWWTQAQAHDLV
IKSLDKLKEVKEFLGENISNFLSLAGNTYQLTRGIGKDIRALRRARANLQSVPHASAS
RPRVTEPISAESGEQVERVNEPSILEMSRGVKLTDVAPVSFFLVLDVVYLVYESKHLH
EGAKSETAEELKKVAQELEEKLNILNNNYKILQADQEL"
BASE COUNT 477 a 378 c 462 g 330 t
ORIGIN
1 gacgcataac tggaggtggg atccacacag ctcagaacag ctggatcttg ctcagtctct
61 gccaggggaa gattccttgg aggaggccct gcagcgacat ggagggagct gctttgctga
121 gagtctctgt cctctgcatc tggatgagtg cacttttcct tggtgtggga gtgagggcag
181 aggaagctgg agcgagggtg caacaaaacg ttccaagtgg gacagatact ggagatcctc
241 aaagtaagcc cctcggtgac tgggctgctg gcaccatgga cccagagagc agtatcttta
301 ttgaggatgc cattaagtat ttcaaggaaa aagtgagcac acagaatctg ctactcctgc
361 tgactgataa tgaggcctgg aacggattcg tggctgctgc tgaactgccc aggaatgagg
421 cagatgagct ccgtaaagct ctggacaacc ttgcaagaca aatgatcatg aaagacaaaa
481 actggcacga taaaggccag cagtacagaa actggtttct gaaagagttt cctcggttga
541 aaagtaagct tgaggataac ataagaaggc tccgtgccct tgcagatggg gttcagaagg
601 tccacaaagg caccaccatc gccaatgtgg tgtctggctc tctcagcatt tcctctggca
661 tcctgaccct cgtcggcatg ggtctggcac ccttcacaga gggaggcagc cttgtactct
721 tggaacctgg gatggagttg ggaatcacag cagctttgac cgggattacc agcagtacca
781 tagactacgg aaagaagtgg tggacacaag cccaagccca cgacctggtc atcaaaagcc
841 ttgacaaatt gaaggaggtg aaggagtttt tgggtgagaa catatccaac tttctttcct
901 tagctggcaa tacttaccaa ctcacacgag gcattgggaa ggacatccgt gccctcagac
961 gagccagagc caatcttcag tcagtaccgc atgcctcagc ctcacgcccc cgggtcactg
1021 agccaatctc agctgaaagc ggtgaacagg tggagagagt taatgaaccc agcatcctgg
1081 aaatgagcag aggagtcaag ctcacggatg tggcccctgt aagcttcttt cttgtgctgg
1141 atgtagtcta cctcgtgtac gaatcaaagc acttacatga gggggcaaag tcagagacag
1201 ctgaggagct gaagaaggtg gctcaggagc tggaggagaa gctaaacatt ctcaacaata
1261 attataagat tctgcaggcg gaccaagaac tgtgaccaca gggcagggca gccaccagga
1321 gagatatgcc tggcaggggc caggacaaaa tgcaaacttt ttttttttct gagacggagt
1381 cttgctctgt cgccaagttg gagcttgcag tgagccgaga tatcgccact gcactccagc
1441 ctgggtgaca gagcgagact ccatctcaaa aaaaaaaaaa aaaaagaata tattgacgga
1501 agaatagaga ggaggcttga aggaaccagc aatgagaagg ccaggaaaag aaagagctga
1561 aaatggagaa agcccaagag ttagaacagt tggatacagg agaagaaaca gcggctccac
1621 tacagaccca gccccaggtt caatgtc
//