LOCUS BC114376 2232 bp mRNA linear HUM 06-JUN-2006
DEFINITION Homo sapiens solute carrier organic anion transporter family,
member 1B1, mRNA (cDNA clone MGC:133282 IMAGE:40037364), complete
cds.
ACCESSION BC114376
VERSION BC114376.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 2232)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 2232)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (03-MAR-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 17 Row: l Column: 8.
FEATURES Location/Qualifiers
source 1..2232
/db_xref="H-InvDB:HIT000340665"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:133282 IMAGE:40037364"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: GATAGTTC"
gene 1..2232
/gene="SLCO1B1"
/gene_synonym="LST-1"
/gene_synonym="OATP-C"
/gene_synonym="OATP1B1"
/gene_synonym="OATP2"
/db_xref="GeneID:10599"
/db_xref="HGNC:HGNC:10959"
/db_xref="MIM:604843"
CDS 100..2175
/gene="SLCO1B1"
/gene_synonym="LST-1"
/gene_synonym="OATP-C"
/gene_synonym="OATP1B1"
/gene_synonym="OATP2"
/codon_start=1
/product="solute carrier organic anion transporter family,
member 1B1"
/protein_id="AAI14377.1"
/db_xref="GeneID:10599"
/db_xref="HGNC:HGNC:10959"
/db_xref="MIM:604843"
/translation="MDQNQHLNKTAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLG
AIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCF
IMGIGGVLTALPHFFMGYYRYSKETNIDSSENSTSTLSTCLINQILSLNRASTEIVGK
GCLKESGSYMWIYVFMGNMLRGIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMI
GPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPF
FFLPQTPNKPQKERKASLSLHVLETNDEKDQTANLTNQGKNITKNVTGFFQSFKSILT
NPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFL
GGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTS
HRDVPLSYCNSDCNCDESQWEPVCGNNGITYISPCLAGCKSSSGNKKPIVFYNCSCLE
VTGLQNRNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPE
LKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRV
YLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASENGSVMDEANLESLNKNKHFVPS
AGADSETHC"
BASE COUNT 689 a 391 c 420 g 732 t
ORIGIN
1 tccgacttgt tgcagttgct gtaggattct aaatccaggt gattgtttca aactgagcat
61 caacaacaaa aacatttgta tgatatctat atttcaatca tggaccaaaa tcaacatttg
121 aataaaacag cagaggcaca accttcagag aataagaaaa caagatactg caatggattg
181 aagatgttct tggcagctct gtcactcagc tttattgcta agacactagg tgcaattatt
241 atgaaaagtt ccatcattca tatagaacgg agatttgaga tatcctcttc tcttgttggt
301 tttattgacg gaagctttga aattggaaat ttgcttgtga ttgtatttgt gagttacttt
361 ggatccaaac tacatagacc aaagttaatt ggaatcggtt gtttcattat gggaattgga
421 ggtgttttga ctgctttgcc acatttcttc atgggatatt acaggtattc taaagaaact
481 aatatcgatt catcagaaaa ttcaacatca accttatcca cttgtttaat taatcaaatt
541 ttatcactca atagagcatc aactgagata gtgggaaaag gttgtttaaa ggaatctggg
601 tcatacatgt ggatatatgt gttcatgggt aatatgcttc gtggaatagg ggagactccc
661 atagtaccac tggggctttc ttacattgat gattttgcta aagaaggaca ttcttctttg
721 tatttaggta tattgaatgc aatagcaatg attggtccaa tcattggctt taccctggga
781 tctctgtttt ctaaaatgta cgtggatatt ggatatgtag atctaagcac tatcaggata
841 actcctactg attctcgatg ggttggagct tggtggctta atttccttgt gtctggacta
901 ttctccatta tttcttccat accattcttt ttcttgcccc aaactccaaa taaaccacaa
961 aaagaaagaa aagcttcact gtctttgcat gtgctggaaa caaatgatga aaaggatcaa
1021 acagctaatt tgaccaatca aggaaaaaat attaccaaaa atgtgactgg ttttttccag
1081 tcttttaaaa gcatccttac taatcccctg tatgttatgt ttgtgctttt gacgttgtta
1141 caagtaagca gctatattgg tgcttttact tatgtcttca aatacgtaga gcaacagtat
1201 ggtcagcctt catctaaggc taacatctta ttgggagtca taaccatacc tatttttgca
1261 agtggaatgt ttttaggagg atatatcatt aaaaaattca aactgaacac cgttggaatt
1321 gccaaattct catgttttac tgctgtgatg tcattgtcct tttacctatt atattttttc
1381 atactctgtg aaaacaaatc agttgccgga ctaaccatga cctatgatgg aaataatcca
1441 gtgacatctc atagagatgt accactttct tattgcaact cagactgcaa ttgtgatgaa
1501 agtcaatggg aaccagtctg tggaaacaat ggaataactt acatctcacc ctgtctagca
1561 ggttgcaaat cttcaagtgg caataaaaag cctatagtgt tttacaactg cagttgtttg
1621 gaagtaactg gtctccagaa cagaaattac tcagcccatt tgggtgaatg cccaagagat
1681 gatgcttgta caaggaaatt ttactttttt gttgcaatac aagtcttgaa tttatttttc
1741 tctgcacttg gaggcacctc acatgtcatg ctgattgtta aaattgttca acctgaattg
1801 aaatcacttg cactgggttt ccactcaatg gttatacgag cactaggagg aattctagct
1861 ccaatatatt ttggggctct gattgataca acgtgtataa agtggtccac caacaactgt
1921 ggcacacgtg ggtcatgtag gacatataat tccacatcat tttcaagggt ctacttgggc
1981 ttgtcttcaa tgttaagagt ctcatcactt gttttatata ttatattaat ttatgccatg
2041 aagaaaaaat atcaagagaa agatatcaat gcatcagaaa atggaagtgt catggatgaa
2101 gcaaacttag aatccttaaa taaaaataaa cattttgtcc cttctgctgg ggcagatagt
2161 gaaacacatt gttaagggga gaaaaaaagc cacttctgct tctgtgtttc caaacagcat
2221 tgcattgatt ca
//