LOCUS BC113953 3617 bp mRNA linear HUM 29-JUN-2006
DEFINITION Homo sapiens transient receptor potential cation channel, subfamily
C, member 1, mRNA (cDNA clone MGC:133335 IMAGE:40067811), complete
cds.
ACCESSION BC113953
VERSION BC113953.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 3617)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 3617)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-FEB-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 17 Row: n Column: 4.
FEATURES Location/Qualifiers
source 1..3617
/db_xref="H-InvDB:HIT000387225"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:133335 IMAGE:40067811"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_283"
/note="Vector: pCR-Blunt II-TOPO with reversed insert;
Clone identification sequence tag: TTGTGGTC"
gene 1..3617
/gene="TRPC1"
/gene_synonym="HTRP-1"
/gene_synonym="TRP1"
/db_xref="GeneID:7220"
/db_xref="HGNC:HGNC:12333"
/db_xref="MIM:602343"
CDS 54..2333
/gene="TRPC1"
/gene_synonym="HTRP-1"
/gene_synonym="TRP1"
/codon_start=1
/product="TRPC1 protein"
/protein_id="AAI13954.1"
/db_xref="GeneID:7220"
/db_xref="HGNC:HGNC:12333"
/db_xref="MIM:602343"
/translation="MMAALYPSTDLSGASSSSLPSSPSSSSPNEVMALKDVREVKEEN
TLNEKLFLLACDKGDYYMVKKILEENSSGDLNINCVDVLGRNAVTITIENENLDILQL
LLDYGCQKLMERIQNPEYSTTMDVAPVILAAHRNNYEILTMLLKQDVSLPKPHAVGCE
CTLCSAKNKKDSLRHSRFRLDIYRCLASPALIMLTEEDPILRAFELSADLKELSLVEV
EFRNDYEELARQCKMFAKDLLAQARNSRELEVILNHTSSDEPLDKRGLLEERMNLSRL
KLAIKYNQKEFVSQSNCQQFLNTVWFGQMSGYRRKPTCKKIMTVLTVGIFWPVLSLCY
LIAPKSQFGRIIHTPFMKFIIHGASYFTFLLLLNLYSLVYNEDKKNTMGPALERIDYL
LILWIIGMIWSDIKRLWYEGLEDFLEESRNQLSFVMNSLYLATFALKVVAHNKFHDFA
DRKDWDAFHPTLVAEGLFAFANVLSYLRLFFMYTTSSILGPLQISMGQMLQDFGKFLG
MFLLVLFSFTIGLTQLYDKGYTSKEQKDCVGIFCEQQSNDTFHSFIGTCFALFWYIFS
LAHVAIFVTRFSYGEELQSFVGAVIVGTYNVVVVIVLTKLLVAMLHKSFQLIANHEDK
EWKFARAKLWLSYFDDKCTLPPPFNIIPSPKTICYMISSLSKWICSHTSKGKVKRQNS
LKEWRNLKQKRDENYQKVMCCLVHRYLTSMRQKMQSTDQATVENLNELRQDLSKFRNE
IRDLLGFRTSKYAMFYPRN"
BASE COUNT 1071 a 604 c 700 g 1242 t
ORIGIN
1 ccgaggcagc agtgggaacg actcatcctt tttccagccc ttcatgggcc gcgatgatgg
61 cggccctgta cccgagcacg gacctctcgg gcgcctcctc ctcctccctg ccttcctctc
121 catcctcttc ctcgccgaac gaggtgatgg cgctgaagga tgtgcgggag gtgaaggagg
181 agaatacgct gaatgagaag cttttcttgc tggcgtgcga caagggtgac tattatatgg
241 ttaaaaagat tttggaggaa aacagttcag gtgacttgaa cataaattgc gtagatgtgc
301 ttgggagaaa tgctgttacc ataactattg aaaacgaaaa cttggatata ctgcagcttc
361 ttttggacta cggttgtcag aaactaatgg aacgaattca gaatcctgag tattcaacaa
421 ctatggatgt tgcacctgtc attttagctg ctcatcgtaa caactatgaa attcttacaa
481 tgctcttaaa acaggatgta tctctaccca agccccatgc agttggctgt gaatgcacat
541 tgtgttctgc aaaaaacaaa aaggatagcc tccggcattc caggtttcgt cttgatatat
601 atcgatgttt ggccagtcca gctctaataa tgttaacaga ggaggatcca attctgagag
661 catttgaact tagtgctgat ttaaaagaac taagtcttgt ggaggtggaa ttcaggaatg
721 attatgagga actagcccgg caatgtaaaa tgtttgctaa ggatttactt gcacaagccc
781 ggaattctcg tgaattggaa gttattctaa accatacgtc tagtgacgag cctcttgaca
841 aacggggatt attagaagaa agaatgaatt taagtcgtct aaaacttgct atcaaatata
901 accagaaaga gtttgtctcc cagtctaact gccagcagtt cctgaacact gtttggtttg
961 gacagatgtc gggttaccga cgcaagccca cctgtaagaa gataatgact gttttgacag
1021 taggcatctt ttggccagtt ttgtcacttt gttatttgat agctcccaaa tctcagtttg
1081 gcagaatcat tcacacacct tttatgaaat ttatcattca tggagcatca tatttcacat
1141 ttctgctgtt gcttaatcta tactctcttg tctacaatga ggataagaaa aacacaatgg
1201 ggccagccct tgaaagaata gactatcttc ttattctgtg gattattggg atgatttggt
1261 cagacattaa aagactctgg tatgaagggt tggaagactt tttagaagaa tctcgtaatc
1321 aactcagttt tgtcatgaat tctctttatt tggcaacctt tgccctcaaa gtggttgctc
1381 acaacaagtt tcatgatttt gctgatcgga aggattggga tgcattccat cctacactgg
1441 tggcagaagg gctttttgca tttgcaaatg ttctaagtta tcttcgtctc ttttttatgt
1501 atacaaccag ctctatcttg ggtccattac agatttcaat gggacagatg ttacaagatt
1561 ttggaaaatt tcttgggatg tttcttcttg ttttgttttc tttcacaatt ggactgacac
1621 aactgtatga taaaggatat acttcaaagg agcagaagga ctgtgtaggc atcttctgtg
1681 aacagcaaag caatgatacc ttccattcgt tcattggcac ctgctttgct ttgttctggt
1741 atattttctc cttagcgcat gtggcaatct ttgtcacaag atttagctat ggagaagaac
1801 tgcagtcctt tgtgggagct gtcattgttg gtacatacaa tgtcgtggtt gtgattgtgc
1861 ttaccaaact gctggtggca atgcttcata aaagctttca gttgatagca aatcatgaag
1921 acaaagaatg gaagtttgct cgagcaaaat tatggcttag ctactttgat gacaaatgta
1981 cgttacctcc acctttcaac atcattccct caccaaagac tatctgctat atgattagta
2041 gcctcagtaa gtggatttgc tctcatacat caaaaggcaa ggtcaaacgg caaaacagtt
2101 taaaggaatg gaggaatttg aaacagaaga gagatgaaaa ctatcaaaaa gtgatgtgct
2161 gcctagtgca tcgttacttg acttccatga gacagaagat gcaaagtaca gatcaggcaa
2221 ctgtggaaaa tctaaacgaa ctgcgccaag atctgtcaaa attccgaaat gaaataaggg
2281 atttacttgg ctttcggact tctaaatatg ctatgtttta tccaagaaat taaccatttt
2341 ctaaatcatg gagcgaataa ttttcaataa cagatccaaa agactatatt gcataacttg
2401 caatgaaatt aatgagatat atattgaaat aaagaattat gtaaaagcca ttctttaaaa
2461 tatttatagc ataaatatat gttatgtaaa gtgtgtatat agaattagtt ttttaaacct
2521 tctgttagtg gctttttgca gaagcaaaac agattaagta gatagatttt gttagcatgc
2581 tgcttggttt tcttacttag tgctttaaaa tgtttttttt atgtttaaga ggggcagtta
2641 taaatggaca cattgcccag aatgttttgt aaaatgaaga ccagcaaatg taggctgatc
2701 tccttcacag gatacacttg aaatatagaa gttatgtttt aaatatctct gttttaggag
2761 ttcacatata gttcagcatt tattgtttag gagtataatt ttattttatc taaaataata
2821 gtctattttt tcttttgtat tttgttataa tcttaagcaa caaagaaaaa accctaatat
2881 ttgaatctat ttatgtcttt caatttaaat tcacttcagt ttttgttatt gtaatatatt
2941 tacttttaca tggttataat cactttatat ttttaatgtt tttttcactt aatattttat
3001 atatacattt ccatgtattg atgtagttag tccacattta aatttttata gaattatata
3061 gtttttgaaa aatacagtca gtagatgttt tattttttag ctattcagtt atgtttataa
3121 gtttgcatag ctacttctcg acatttggtt tgttttaatt tttttgtatc ataatagtcc
3181 tatttttttt tcaagttgga gtgaatgttt ttagttttaa gatagatagg agacactttt
3241 ttatcacatg tagtcacaac ctgttttgtt tttgtaaaac ataggaagtc tctttaatgc
3301 aatgatttgt tttatatttg gactaaggtt cttgagctta tctcccaagg tactttccat
3361 aatttaacac agcttctata aaagtgactt catgcttact tgtggatcat tcttgctgct
3421 taagatgaaa agcattggtt ttttaaaatt agagaataaa atatgtattt aaatttttgg
3481 tgtgttcaca taaagggatg tagctaaaat gttttcatag gctattatat attctcgcag
3541 catttccagt taagaggata ttaggtatat aattctcttc ttaaccgaat gtcagatggt
3601 cttacgccac agggtgc
//