LOCUS BC113950 5806 bp mRNA linear HUM 15-JUL-2006
DEFINITION Homo sapiens phospholipase C, eta 1, mRNA (cDNA clone MGC:117152
IMAGE:5501480), complete cds.
ACCESSION BC113950
VERSION BC113950.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5806)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5806)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (24-FEB-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: ATCC
cDNA Library Preparation: Life Technologies, Inc.
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAK Plate: 233 Row: j Column: 23
This clone was selected for full length sequencing because it
passed the following selection criteria: matched mRNA gi: 57863297.
FEATURES Location/Qualifiers
source 1..5806
/db_xref="H-InvDB:HIT000340616"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:117152 IMAGE:5501480"
/tissue_type="Eye, retinoblastoma"
/clone_lib="NIH_MGC_67"
/lab_host="DH10B"
/note="Vector: pCMV-SPORT6"
gene 1..5806
/gene="PLCH1"
/gene_synonym="MGC117152"
/gene_synonym="PLCeta1"
/db_xref="GeneID:23007"
/db_xref="HGNC:HGNC:29185"
CDS 75..5042
/gene="PLCH1"
/gene_synonym="MGC117152"
/gene_synonym="PLCeta1"
/codon_start=1
/product="phospholipase C, eta 1"
/protein_id="AAI13951.1"
/db_xref="GeneID:23007"
/db_xref="HGNC:HGNC:29185"
/translation="MSVMQSGTQMIKLKRGTKGLVRLFYLDEHRTRLRWRPSRKSEKA
KILIDSIYKVTEGRQSEIFHRQAEGNFDPSCCFTIYHGNHMESLDLITSNPEEARTWI
TGLKYLMAGISDEDSLAKRQRTHDQWVKQTFEEADKNGDGLLNIEEIHQLMHKLNVNL
PRRKVRQMFQEADTDENQGTLTFEEFCVFYKMMSLRRDLYLLLLSYSDKKDHLTVEEL
AQFLKVEQKMNNVTTDYCLDIIKKFEVSEENKVKNVLGIEGFTNFMRSPACDIFNPLH
HEVYQDMDQPLCNYYIASSHNTYLTGDQLLSQSKVDMYARVLQEGCRCVEVDCWDGPD
GEPVVHHGYTLTSKILFRDVVETINKHAFVKNEFPVILSIENHCSIQQQRKIAQYLKG
IFGDKLDLSSVDTGECKQLPSPQSLKGKILVKGKKLPYHLGDDAEEGEVSDEDSADEI
EDECKFKLHYSNGTTEHQVESFIRKKLESLLKESQIRDKEDPDSFTVRALLKATHEGL
NAHLKQSPDVKESGKKSHGRSLMTNFGKHKKTTKSRSKSYSTDDEEDTQQSTGKEGGQ
LYRLGRRRKTMKLCRELSDLVVYTNSVAAQDIVDDGTTGNVLSFSETRAHQVVQQKSE
QFMIYNQKQLTRIYPSAYRIDSSNFNPLPYWNAGCQLVALNYQSEGRMMQLNRAKFKA
NGNCGYVLKPQQMCKGTFNPFSGDPLPANPKKQLILKVISGQQLPKPPDSMFGDRGEI
IDPFVEVEIIGLPVDCCKDQTRVVDDNGFNPVWEETLTFTVHMPEIALVRFLVWDHDP
IGRDFVGQRTVTFSSLVPGYRHVYLEGLTEASIFVHITINEIYGKNRQLQGLKGLFNK
NPRHSSSENNSHYVRKRSIGDRILRRTASAPAKGRKKSKMGFQEMVEIKDSVSEATRD
QDGVLRRTTRSLQARPVSMPVDRNLLGALSLPVSETAKDIEGKENSLAEDKDGRRKGK
ASIKDPHFLNFNKKLSSSSSALLHKDTSQGDTIVSTAHMSVTGEQLGMSSPRGGRTTS
NATSNCQENPCPSKSLSPKQHLAPDPVVNPTQDLHGVKIKEKGNPEDFVEGKSILSGS
VLSHSNLEIKNLEGNRGKGRAATSFSLSDVSMLCSDIPDLHSTAILQESVISHLIDNV
TLTNENEPGSSISALIGQFDETNNQALTVVSHLHNTSVMSGHCPLPSLGLKMPIKHGF
CKGKSKSSFLCSSPELIALSSSETTKHATNTVYETTCTPISKTKPDDDLSSKAKTAAL
ESNLPGSPNTSRGWLPKSPTKGEDWETLKSCSPASSPDLTLEDVIADPTLCFNSGESS
LVEIDGESENLSLTTCEYRREGTSQLASPLKLKYNQGVVEHFQRGLRNGYCKETLRPS
VPEIFNNIQDVKTQSISYLAYQGAGFVHNHFSDSDAKMFQTCVPQQSSAQDMHVPVPK
QLAHLPLPALKLPSPCKSKSLGDLTSEDIACNFESKYQCISKSFVTTGIRDKKGVTVK
TKSLEPIDALTEQLRKLVSFDQEDNCQVLYSKQDANQLPRALVRKLSSRSQSRVRNIA
SRAKEKQEANKQKVPNPSNGAGVVLRNKPSAPTPAVNRHSTGSYIAGYLKNTKGGGLE
GRGIPEGACTALHYGHVDQFCSDNSVLQTEPSSDDKPEIYFLLRL"
BASE COUNT 1743 a 1280 c 1314 g 1469 t
ORIGIN
1 tggaaaaaag gaactgtgtg cagtaccgca ggcattttct ggtggacaac agtgtgtttc
61 atgttgaaag atgcatgagt gtgatgcagt ccgggacaca gatgatcaag ctgaaacgtg
121 gaaccaaagg gcttgtccgc ctcttttacc tggatgagca ccggacacgc ctccgatggc
181 gaccctctag gaagagcgag aaggcaaaaa tacttattga ttccatttac aaagtgactg
241 agggccggca gtctgaaata ttccacagac aagctgaggg gaacttcgac cccagctgct
301 gcttcaccat ctaccatggc aaccacatgg agtccctgga cctcatcacc tccaaccccg
361 aggaggcccg cacctggatc acaggcctca agtacctgat ggctggcatc agtgatgaag
421 actcccttgc caaaaggcag aggacccatg accaatgggt gaagcagacc tttgaggaag
481 ctgataagaa tggtgacggc ttgctgaata ttgaagagat acatcagctg atgcataaac
541 tgaatgttaa tctgccccga agaaaagtca gacaaatgtt tcaggaagcc gacacagatg
601 agaatcaggg aactttgaca tttgaagagt tctgtgtttt ttacaaaatg atgtctttga
661 gacgagacct ttatttgtta cttttgagct acagtgacaa gaaagatcac ctaactgtgg
721 aagaactggc tcagtttttg aaggtggagc aaaagatgaa taatgtgaca acggactatt
781 gtcttgacat cataaagaag tttgaagttt cagaagaaaa taaggtgaaa aatgttcttg
841 gcatagaagg cttcacgaac ttcatgcgta gtcctgcctg tgacatattt aacccattgc
901 accatgaagt gtaccaagac atggatcagc ccctctgcaa ctactacatt gcttcctctc
961 acaatacata cctgactgga gaccagctcc tttctcagtc caaagtggat atgtatgcac
1021 gggtgctgca agagggctgt cgctgtgtgg aagttgactg ttgggatggc ccagatggag
1081 agccagtagt acatcatggt tacactctca cttcaaaaat tctcttcaga gatgttgtgg
1141 agaccatcaa caagcatgcc tttgtgaaga atgagtttcc tgttatattg tctatcgaga
1201 atcactgcag tatccagcag caaaggaaga ttgctcagta cctgaaagga atattcggag
1261 acaaactgga cctgtcatct gttgatacag gggagtgcaa gcagcttcca agccctcaaa
1321 gtttgaaagg caaaattcta gtgaagggta agaagttgcc ttatcacctt ggggatgatg
1381 cagaggaagg ggaagtttct gatgaggaca gtgcagatga aattgaagac gagtgcaaat
1441 tcaagctcca ttatagtaat gggaccactg agcatcaggt ggaatctttc ataaggaaaa
1501 aactggagtc actgttaaaa gaatctcaaa ttcgagataa agaagatcct gatagtttca
1561 cagtgcgggc actactgaag gccacgcatg aaggcttaaa tgcacacctg aagcagagtc
1621 cagatgtaaa ggaaagtgga aagaaatcac atggacgatc cctcatgacc aactttggaa
1681 aacataagaa aactacaaaa tcacggtcta aatcttacag tactgatgat gaggaagaca
1741 cacagcagag tactggcaag gagggtggcc agctgtacag attgggtcgc cgaaggaaaa
1801 ccatgaagct ctgccgagaa ctctctgatt tggttgtgta cacaaactcc gtggccgctc
1861 aggacattgt ggatgacgga accacaggaa atgtgttatc attcagtgaa acaagagcac
1921 atcaggttgt tcagcaaaaa tcagagcagt tcatgattta taatcaaaag caactcacga
1981 ggatttaccc ctctgcctac cgcattgatt ccagtaactt caaccctctc ccctactgga
2041 acgcaggctg ccagctagtg gcactgaatt atcaatctga aggacgaatg atgcagttaa
2101 accgagccaa attcaaggca aatggcaatt gtggctatgt cctcaaaccc cagcaaatgt
2161 gcaaaggtac tttcaaccct ttctctggtg accctcttcc tgccaacccc aaaaagcagc
2221 tcatcctgaa agttatcagt ggacagcaac tccccaaacc tccagactcc atgtttggag
2281 atcgaggcga gatcattgac ccttttgttg aagttgaaat tattggattg ccagtagatt
2341 gttgtaaaga tcaaacccgt gtggtagatg acaatggatt taaccctgtg tgggaagaaa
2401 cactgacatt tacagtacac atgccagaaa tagctttggt tcggttcctt gtgtgggatc
2461 acgatcccat tggacgagac tttgttggac aaagaactgt gaccttcagc agcttagtgc
2521 ctggctaccg gcatgtctat ttggaaggac tgacagaagc atccatattt gtacacataa
2581 ccatcaatga aatctatgga aagaacagac aactccaggg tctgaaggga ctgttcaata
2641 agaatcctag gcacagttct tcagaaaaca attcccatta tgtacggaag cgatccattg
2701 gagatagaat tctgcgacgc acagctagcg ccccagccaa aggcaggaaa aagagcaaaa
2761 tgggcttcca agaaatggtg gagataaagg attctgtgtc cgaggccaca agagatcaag
2821 atggcgtgct gaggaggacc acacgcagtt tgcaagcacg ccctgtctct atgcctgttg
2881 acagaaacct tctgggagct ttgtcgctgc ctgtatctga aacagcaaaa gacattgaag
2941 gaaaagaaaa ctctctagca gaagataaag atggcagaag aaaagggaaa gcaagtataa
3001 aagatccaca ttttctaaat ttcaacaaaa agttatcatc ctcctccagt gctctgctcc
3061 acaaagatac cagccaaggg gacaccattg tatctactgc ccacatgtca gtcacaggag
3121 aacagctggg catgtcaagt cctaggggtg ggagaaccac atcaaatgcc acaagcaatt
3181 gccaggaaaa cccctgtccc agcaagtctc tctccccaaa gcagcatttg gctcccgatc
3241 ctgtagttaa ccccacacaa gatctgcatg gtgtgaaaat caaggaaaag ggtaatcctg
3301 aggactttgt ggaagggaaa agcatcttgt caggaagcgt cctttctcat agcaacctag
3361 aaattaagaa cctggaaggt aataggggta agggccgagc tgcaacatcc ttttctttgt
3421 cagacgtctc catgctctgt tctgacatac ctgacctaca ttcaactgca attctgcagg
3481 agagtgtaat ttcccatctt attgacaatg tcactttaac aaatgagaat gagccgggca
3541 gttccatctc agccctgatt ggccagtttg atgagaccaa caatcaggct ctcacagttg
3601 tttctcatct tcataatacc agtgtgatgt caggccattg tcccttgcct agcctgggcc
3661 taaaaatgcc catcaagcat ggtttttgca agggaaaatc caagtcttcc ttcctgtgct
3721 catctccgga gctgatagca ctctcgagtt ctgagaccac caaacatgca acgaacacag
3781 tttatgaaac tacctgcact cccatctcta aaaccaaacc agatgatgac ctttctagta
3841 aggccaagac agcggcctta gaaagcaacc tgcctggatc ccctaatact tctcgtggct
3901 ggttaccaaa aagtcctacc aagggagaag actgggaaac actgaagagc tgcagccctg
3961 cctcttcccc tgatttgacc ctggaggatg taatagctga tcccactctc tgtttcaatt
4021 ctggggagag cagccttgtg gaaattgatg gagaatcaga aaatctttct ctaacaacct
4081 gtgaatatag gagagagggc acaagtcaac ttgcttctcc tttaaaactc aagtacaatc
4141 agggtgtggt agaacacttt caaagaggtt tgagaaacgg ctactgtaaa gagaccctcc
4201 gcccttctgt ccctgaaata ttcaacaata ttcaagatgt caaaactcaa agtatttctt
4261 atctagccta tcagggtgct ggctttgtgc ataatcattt ctcagattca gatgcaaaaa
4321 tgttccagac ctgtgtgccc cagcaatcta gtgctcaaga tatgcatgtc cctgtaccca
4381 agcagttggc acatcttcct ttgcctgctc tgaaactgcc tagtccttgc aaatccaaaa
4441 gtctggggga cttaacatca gaggacattg cctgcaattt tgagagcaag taccagtgta
4501 ttagtaagag ttttgttaca actggcatta gagacaagaa gggcgtgact gtgaagacaa
4561 agtcgttaga gcctatagat gccctgaccg agcagcttcg gaagcttgtg tcctttgacc
4621 aggaagacaa ctgccaagtg ctatattcaa agcaggatgc caatcagctc ccccgggcac
4681 tggtcaggaa gttgtcatcc agaagtcaga gcagagtgcg caatattgct agtcgtgcca
4741 aggagaaaca ggaagccaac aagcagaaag ttccaaaccc cagcaatggg gcaggagtgg
4801 ttcttagaaa caaaccctca gcacccaccc ctgcagtgaa tcgccactcc accggctcct
4861 acatcgcagg ctacctgaag aacacgaaag ggggtggcct tgaaggccgg ggcatcccag
4921 agggggcatg cacggctctt cactatggcc acgttgacca gttttgttca gataattctg
4981 ttttgcagac tgagccaagc agtgatgata aaccagaaat ttattttctt ttgagactgt
5041 gaattattta aaactgcatt cttaaggttt tcaaggtatt ctgtagaatg tcagagtttt
5101 cagtaaataa gttccttggc tttggaatga ttttcaaatg tatttttaaa cttgtatttg
5161 ggtctccctt tgacttcatg tgttctccct gttaatgcgt ttgtatatag atttggtgac
5221 atttcccatg tacctattat gatctttctc ccttgagttg ttgtaaactg tatcagtatg
5281 aaatatgtgc atgccctaga tgtgaaactc ctcagcagct cgggttataa tgtgtgtgtg
5341 tttcaccaag atgtccttta ctgtgtcctc agattgcagt cacaaatgta gtcattttta
5401 ctctctaact gttgagttga ttaagagact ttgcaaacga caaagggatg aattccttac
5461 tttaatctgt tatcattttt cctatgtttc cctctttgtt cagaagccca gatgcatttt
5521 tataactcag ttttaaaaac tttaaaatag ttaccttgcc ttttaggatg ttcttatccc
5581 acccataatg agagttgaaa ggggatggat agctgctccc catgcccttc ccactttttg
5641 gaataggccg tgagggtgtg aggaagaagg ctgtcttttg tacataagga caaaattgtt
5701 tgttttacat aaattttgtt acatattttt gctaatggct ttgtatgtaa caagaagcga
5761 gttgccaaac taaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaa
//