LOCUS BC113668 5304 bp mRNA linear HUM 29-JUN-2006
DEFINITION Homo sapiens proteasome (prosome, macropain) activator subunit 4,
mRNA (cDNA clone MGC:142228 IMAGE:8322720), complete cds.
ACCESSION BC113668
VERSION BC113668.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5304)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5304)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (21-FEB-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Mike Brownstein, NIMH
cDNA Library Preparation: British Columbia Cancer Research Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: Genome Sequence Centre,
BC Cancer Agency, Vancouver, BC, Canada
info@bcgsc.bc.ca
Martin Hirst, Thomas Zeng, Ryan Morin, Michelle Moksa, Johnson
Pang, Diana Mah, Jing Wang, Kieth Fichter, Eric Chuah, Allen
Delaney, Rob Kirkpatrick, Agnes Baross, Sarah Barber, Mabel
Brown-John, Steve S. Chand, William Chow, Ryan Babakaiff, Dave
Wong, Corey Matsuo, Jaclyn Beland, Susan Gibson, Luis delRio, Ruth
Featherstone, Malachi Griffith, Obi Griffith, Ran Guin, Nancy Liao,
Kim MacDonald, Mike R. Mayo, Josh Moran, Diana Palmquist, JR
Santos, Duane Smailus, Jeff Stott, Miranda Tsai, George Yang,
Jacquie Schein, Asim Siddiqui,Steven Jones, Rob Holt, Marco Marra.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRCB Plate: 5 Row: m Column: 22.
FEATURES Location/Qualifiers
source 1..5304
/db_xref="H-InvDB:HIT000387121"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:142228 IMAGE:8322720"
/tissue_type="Brain, cerebral cortex and lung, PCR rescued
clones"
/clone_lib="NIH_MGC_325"
/note="Vector: pCR-XL-TOPO with reversed insert; Clone
identification sequence tag: CTTGGCAC"
gene 1..5304
/gene="PSME4"
/gene_synonym="KIAA0077"
/gene_synonym="PA200"
/db_xref="GeneID:23198"
/db_xref="HGNC:HGNC:20635"
/db_xref="MIM:607705"
CDS 35..5224
/gene="PSME4"
/gene_synonym="KIAA0077"
/gene_synonym="PA200"
/codon_start=1
/product="proteasome (prosome, macropain) activator
subunit 4"
/protein_id="AAI13669.1"
/db_xref="GeneID:23198"
/db_xref="HGNC:HGNC:20635"
/db_xref="MIM:607705"
/translation="MMQGFARLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTE
HLGLNWFPNSVENILKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEI
FLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDP
YVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIGHAVIWITAMMGGPSKLVQKHLAG
LFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERYKKPSWLTPVPDSHKLTD
QDVTDFVQCIIQPVLLAMFSKTGSLEAAQALQNLALMRPELVIPPVLERTYPALETLT
EPHQLTATLSCVIGVARSLVSGGRWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQF
IATFSTLVPLVDCSSVLQERNDLTEVERELCSATAEFEDFVLQFMDRCFGLIESSTLE
QTREETETEKMTHLESLVELGLSSTFSTILTQCSKEIFMVALQKVFNFSTSHIFETRV
AGRMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMNDDVLNDEELDKELLWNLQLL
SEITRVDGRKLLLYREQLVKILQRTLHLTCKQGYTLSCNLLHHLLRSTTLIYPTEYCS
VPGGFDKPPSEYFPIKDWGKPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELVKLQ
HCGDGKLEMSRDDILQSLTIVHNCLIGSGNLLPPLKGEPVTNLVPSMVSLEETKLYTG
LEYDLSRENHREVIATVIRKLLNHILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFD
SRWKSFNLVKKSMENRLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKKIHQDMIRD
LLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVTQQQFKGAL
YCLLGNHSGVCLANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHRQ
YETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADALRNYE
NLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLPLRAIRFFVENLNHDAIVVRK
MAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQIIAGDRPDNHWLHYDSKTIPRTK
KEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKF
VEQLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHESTQ
RCVAEIIAGLIRGSKHWTFEKVEKLWELLCPLLRTALSNITVETYNDWGACIATSCES
RDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEP
KLTQVYKNVRERIGSVLTYIFMIDVSLPNTTPTISPHVPEFTARILEKLKPLMDVDEE
IQNHVMEENGIGEEDERTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAP
VENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQ
TMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPM
QIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSPYDVPTWMP
QLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPC
YYA"
BASE COUNT 1600 a 1067 c 1127 g 1510 t
ORIGIN
1 tgagctggta tcaattccaa aactggaaat cagcatgatg cagggatttg cccgcctttt
61 gatcaacttg ttaaagaaaa aggaacttct ttcaagagct gatttggagt taccctggag
121 accactttat gacatggtag aaagaatatt atattccaag acagagcacc taggattaaa
181 ttggtttcct aattctgtag aaaatattct caaaacactc gtgaaaagct gccgaccata
241 ttttccagca gatgccaccg ctgagatgct agaagaatgg cgacctttaa tgtgcccttt
301 tgatgtaacc atgcaaaagg ccatcactta ttttgaaata tttcttccta cctcccttcc
361 tccagaactt catcataaag gttttaaact ttggtttgat gaattaattg gcctttgggt
421 ttcagtgcaa aatctcccac aatgggaggg gcaactagta aatctctttg ctcgattggc
481 tacagataat atagggtaca tagattggga tccatatgta ccaaagatat ttacaagaat
541 tctgagaagc ttgaacctcc cagtgggaag cagtcaagtg ttagtcccaa gatttttaac
601 aaatgcttat gatataggac atgctgtaat atggatcacc gccatgatgg gtggaccaag
661 taagctagtg caaaaacact tagctggttt gtttaacagc atcacatctt tttaccatcc
721 ttcaaataat gggcgctggc tgaacaagtt aatgaaacta cttcagcggt tgccaaacag
781 tgttgttaga agattgcatc gtgaaagata caagaagccc tcttggttaa ctcctgtgcc
841 tgatagccac aagcttactg atcaagatgt tacagacttt gtacaatgca ttattcagcc
901 tgtcctcttg gctatgttta gcaaaaccgg tagtctagaa gcagcccagg ctttgcagaa
961 tcttgcactc atgagacctg aattggtaat accccctgta cttgaaagaa catatcctgc
1021 attagagaca ttaacagaac ctcaccagct cacagctact ttaagttgtg taattggagt
1081 agcccgcagt ttggtatcag gaggcagatg gtttcctgaa ggtcctacac atatgctacc
1141 tctgttgatg agagcattgc ctggggtgga tccaaatgac tttagtaaat gcatgatcac
1201 attccagttc atagcaacat tttctactct ggtgccttta gtagattgtt catctgtact
1261 acaagaaaga aatgacctca cagaagtgga acgagaactt tgttcagcca cagctgaatt
1321 tgaggatttc gtcttacagt ttatggacag atgttttgga cttatagaaa gtagcacatt
1381 ggagcaaaca agagaagaga cagaaactga gaaaatgaca cacttggaga gtttggtcga
1441 attaggtctg tcttctacgt ttagtacaat cctcacccaa tgttccaaag aaatatttat
1501 ggtggccctt cagaaggttt ttaatttttc tacttcacat atatttgaaa caagagtagc
1561 aggtcgcatg gtggcagaca tgtgccgcgc tgctgtaaag tgctgcccag aagaatcttt
1621 gaagctcttt gttccccact gctgcagtgt tataactcag cttacaatga atgatgatgt
1681 attaaatgat gaagagctag acaaggaatt actatggaat cttcaacttt tgtctgagat
1741 tactcgagtg gatggaagga agttgcttct ttatagggag cagcttgtaa agattctcca
1801 aagaacccta catttaacct gtaagcaggg ttacactctg tcttgtaacc ttttgcatca
1861 tcttctccgt tctaccacac ttatctaccc tacagaatac tgcagtgtgc caggtggctt
1921 tgacaagcct ccttctgaat actttcctat caaggactgg ggcaaacccg gggacttgtg
1981 gaatctggga atccagtggc atgttccttc ttcagaagaa gtgtcttttg ccttttatct
2041 tttggactcc tttcttcagc ctgagctcgt caaactccag cattgtgggg atggaaaact
2101 tgaaatgtct agagatgata ttctacagag tctgactata gtgcacaact gtttaattgg
2161 ctctggaaac ctcctacctc cgttgaaagg agagccagtt actaacttag taccaagtat
2221 ggtgtccttg gaagagacaa agttgtatac tggacttgaa tatgatctgt ctcgagagaa
2281 ccaccgagaa gtaattgcta cagttataag gaaacttctt aaccacatac ttgataattc
2341 agaagatgat actaagtcat tgtttcttat tataaagatt attggagacc ttttacaatt
2401 ccaaggatct cacaagcatg aatttgactc ccgatggaaa agcttcaact tagtaaagaa
2461 atcaatggaa aatcggctcc atgggaaaaa acaacatatc agagcactgt tgattgatag
2521 agtaatgtta cagcatgagc tacggacact aactgttgag ggttgtgaat acaaaaagat
2581 acatcaagat atgatcagag atcttcttcg tttatctaca agttcataca gtcaggtgag
2641 aaataaggct cagcaaacat tttttgctgc cttgggagca tataacttct gttgcagaga
2701 tatcattccc ttggttttgg agttcttaag gcctgataga caaggtgtta cacagcaaca
2761 attcaagggt gccttgtact gtctccttgg aaatcacagt ggtgtgtgct tggcaaacct
2821 tcatgattgg gactgtattg tacagacgtg gccagcgatt gtttcttcag ggcttagcca
2881 agcaatgtcc ctggaaaagc catcaatagt gagattgttt gatgatcttg cagaaaagat
2941 tcataggcag tatgaaacaa ttggcttgga cttcacaatt ccaaagtcat gtgttgaaat
3001 agcggaatta cttcaacagt caaaaaaccc ctctatcaac cagatattgc ttagcccaga
3061 aaaaattaag gaaggaatta aacgccaaca ggaaaagaat gccgatgccc taaggaacta
3121 tgaaaatttg gtagacacct tgctagatgg tgtggagcaa agaaacctgc cctggaaatt
3181 tgaacatata ggcattgggc ttctgtctct actgctgaga gatgaccgag tgttgcctct
3241 tcgtgccata cggttttttg ttgagaatct caaccatgat gcaattgtag ttcgaaagat
3301 ggctatctca gctgttgctg gtatccttaa acagctaaaa agaacccaca aaaagctgac
3361 cattaacccc tgtgaaatca gtggatgccc taaacccacc caaattattg ctggtgatag
3421 gcctgataat cattggttgc attatgacag caaaactata ccaagaacta aaaaagaatg
3481 ggagtcaagt tgctttgtgg aaaaaactca ctggggatac tacacctggc caaagaatat
3541 ggttgtttat gctggtgtgg aagagcagcc taagcttggc agaagcaggg aggatatgac
3601 agaggcagaa cagattatat ttgatcattt ttctgatcct aaatttgttg agcagttaat
3661 tacttttcta tcattagaag acagaaaagg aaaagataag tttaatccac gacgtttttg
3721 cctctttaag ggtatattca ggaattttga tgatgccttc ctgccagttc tgaagcccca
3781 tttagaacat ttggttgcag attcacatga aagcacccag cgatgtgttg cagaaattat
3841 agctggttta atcagaggtt ctaagcactg gacatttgaa aaggtggaga agctttggga
3901 gcttctgtgc cctctgctta gaacagcact gtccaatatt accgtagaaa cttataatga
3961 ctggggagct tgtatagcaa catcctgtga aagcagagat ccccggaaac ttcactggct
4021 ttttgaactg ctgttggaat caccattgag tggtgaagga ggatcctttg tagatgcatg
4081 tcgactttat gtactacaag gtggccttgc ccagcaagaa tggagagtgc ctgaactatt
4141 gcacagacta ctgaagtact tggaacccaa actcacccag gtttacaaaa atgtcagaga
4201 aagaatagga agtgtgctga cctacatatt catgatagat gtatctttgc caaataccac
4261 accaaccata tcgcctcatg tccctgagtt tactgctcga attctggaga aattgaaacc
4321 tctcatggat gtggatgaag aaattcagaa ccatgttatg gaagaaaatg gaattggtga
4381 agaagatgag cgaactcagg gcattaaact cttgaaaacc atattgaaat ggctgatggc
4441 aagtgcagga agatcctttt ctacagcagt tacagaacaa cttcagcttc tacctttgtt
4501 tttcaagatt gccccagtgg aaaatgacaa tagctacgat gaactgaaaa gagatgcaaa
4561 gttatgttta tcattaatgt ctcaggggtt gctttaccct catcaagtgc ctttggtact
4621 tcaggtgcta aaacaaacag caagaagcag ttcttggcat gcacgataca cagtactgac
4681 ctacctccag accatggtat tttataacct ctttattttc ctaaacaatg aagatgcagt
4741 taaagatatc aggtggctgg ttataagtct tttggaggac gaacaactgg aggttcgaga
4801 aatggctgct actaccttaa gcggtctgct acagtgtaac tttcttacca tggacagtcc
4861 tatgcagatt cattttgagc aactttgcaa aacaaaacta cctaagaaaa gaaagcgaga
4921 ccctggttct gtaggagata ccattccttc tgcagagttg gtcaaacgcc atgctggggt
4981 gctaggactt ggtgcatgtg ttctttctag tccttacgat gttcccacct ggatgcccca
5041 gctcctcatg aatctcagtg cacatctaaa tgatcctcag cctattgaga tgactgtaaa
5101 aaaaacctta tccaatttcc gaaggactca ccatgacaac tggcaggaac ataaacagca
5161 attcactgat gaccaactgc ttgttctcac cgatcttctt gtgtcaccat gctattatgc
5221 atagaaagat gactagtcct cacttcaggc tcttttcatc aaaaattcca caccctcagg
5281 taccatctgt ggtggctctc tgca
//