LOCUS BC112342 5216 bp mRNA linear HUM 29-JUN-2006
DEFINITION Homo sapiens transient receptor potential cation channel, subfamily
M, member 2, mRNA (cDNA clone MGC:133383 IMAGE:40069893), complete
cds.
ACCESSION BC112342
VERSION BC112342.1
KEYWORDS MGC.
SOURCE Homo sapiens (human)
ORGANISM Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
Catarrhini; Hominidae; Homo.
REFERENCE 1 (bases 1 to 5216)
AUTHORS Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G.,
Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D.,
Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K.,
Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F.,
Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L.,
Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L.,
Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S.,
Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J.,
Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J.,
McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S.,
Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W.,
Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A.,
Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S.,
Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y.,
Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D.,
Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M.,
Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E.,
Schnerch,A., Schein,J.E., Jones,S.J. and Marra,M.A.
CONSRTM Mammalian Gene Collection Program Team
TITLE Generation and initial analysis of more than 15,000 full-length
human and mouse cDNA sequences
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002)
PUBMED 12477932
REFERENCE 2 (bases 1 to 5216)
CONSRTM NIH MGC Project
TITLE Direct Submission
JOURNAL Submitted (20-JAN-2006) National Institutes of Health, Mammalian
Gene Collection (MGC), Bethesda, MD 20892-2590, USA
REMARK NIH-MGC Project URL: http://mgc.nci.nih.gov
COMMENT Contact: MGC help desk
Email: cgapbs-r@mail.nih.gov
Tissue Procurement: Baylor Human Genome Sequencing Center
cDNA Library Preparation: Baylor Human Genome Sequencing Center
cDNA Library Arrayed by: The I.M.A.G.E. Consortium (LLNL)
DNA Sequencing by: National Institutes of Health Intramural
Sequencing Center (NISC),
Gaithersburg, Maryland;
Web site: http://www.nisc.nih.gov/
Contact: nisc_mgc@nhgri.nih.gov
Akhter,N., Ayele,K., Beckstrom-Sternberg,S.M., Benjamin,B.,
Blakesley,R.W., Bouffard,G.G., Breen,K., Brinkley,C., Brooks,S.,
Dietrich,N.L., Granite,S., Guan,X., Gupta,J., Haghighi,P.,
Hansen,N., Ho,S.-L., Karlins,E., Kwong,P., Laric,P., Legaspi,R.,
Maduro,Q.L., Masiello,C., Maskeri,B., Mastrian,S.D.,McCloskey,J.C.,
McDowell,J., Pearson,R., Stantripop,S., Thomas,P.J., Touchman,J.W.,
Tsurgeon,C., Vogt,J.L., Walker,M.A., Wetherby,K.D., Wiggins,L.,
Young,A., Zhang,L.-H. and Green,E.D.
Clone distribution: MGC clone distribution information can be found
through the I.M.A.G.E. Consortium/LLNL at: http://image.llnl.gov
Series: IRAM Plate: 17 Row: p Column: 3.
FEATURES Location/Qualifiers
source 1..5216
/db_xref="H-InvDB:HIT000386663"
/organism="Homo sapiens"
/mol_type="mRNA"
/db_xref="taxon:9606"
/clone="MGC:133383 IMAGE:40069893"
/tissue_type="PCR rescued clones"
/clone_lib="NIH_MGC_282"
/note="Vector: pCR-Blunt II-TOPO; Clone identification
sequence tag: TAATAT"
gene 1..5216
/gene="TRPM2"
/gene_synonym="EREG1"
/gene_synonym="KNP3"
/gene_synonym="LTRPC2"
/gene_synonym="NUDT9H"
/gene_synonym="NUDT9L1"
/db_xref="GeneID:7226"
/db_xref="HGNC:HGNC:12339"
/db_xref="MIM:603749"
CDS 14..4675
/gene="TRPM2"
/gene_synonym="EREG1"
/gene_synonym="KNP3"
/gene_synonym="LTRPC2"
/gene_synonym="NUDT9H"
/gene_synonym="NUDT9L1"
/codon_start=1
/product="TRPM2 protein"
/protein_id="AAI12343.1"
/db_xref="GeneID:7226"
/db_xref="HGNC:HGNC:12339"
/db_xref="MIM:603749"
/translation="MEPSALRKAGSEQEEGFEGLPRRVTDLGMVSNLRRSNSSLFKSW
RLQCPFGNNDKQESLSSWIPENIKKKECVYFVESSKLSDAGKVVCQCGYTHEQHLEEA
TKPHTFQGTQWDPKKHVQEMPTDAFGDIVFTGLSQKVKKYVRVSQDTPSSVIYHLMTQ
HWGLDVPNLLISVTGGAKNFNMKPRLKSIFRRGLVKVAQTTGAWIITGGSHTGVMKQV
GEAVRDFSLSSSYKEGELITIGVATWGTVHRREGLIHPTGSFPAEYILDEDGQGNLTC
LDSNHSHFILVDDGTHGQYGVEIPLRTRLEKFISEQTKERGGVAIKIPIVCVVLEGGP
GTLHTIDNATTNGTPCVVVEGSGRVADVIAQVANLPVSDITISLIQQKLSVFFQEMFE
TFTESRIVEWTKKIQDIVRRRQLLTVFREGKDGQQDVDVAILQALLKASRSQDHFGHE
NWDHQLKLAVAWNRVDIARSEIFMDEWQWKPSDLHPTMTAALISNKPEFVKLFLENGV
QLKEFVTWDTLLYLYENLDPSCLFHSKLQKVLVEDPERPACAPAAPRLQMHHVAQVLR
ELLGDFTQPLYPRPRHNDRLRLLLPVPHVKLNVQGVSLRSLYKRSSGHVTFTMDPIRD
LLIWAIVQNRRELAGIIWAQSQDCIAAALACSKILKELSKEEEDTDSSEEMLALAEEY
EHRAIGVFTECYRKDEERAQKLLTRVSEAWGKTTCLQLALEAKDMKFVSHGGIQAFLT
KVWWGQLSVDNGLWRVTLCMLAFPLLLTGLISFREKRLQDVGTPAARARAFFTAPVVV
FHLNILSYFAFLCLFAYVLMVDFQPVPSWCECAIYLWLFSLVCEEMRQLFYDPDECGL
MKKAALYFSDFWNKLDVGAILLFVAGLTCRLIPATLYPGRVILSLDFILFCLRLMHIF
TISKTLGPKIIIVKRMMKDVFFFLFLLAVWVVSFGVAKQAILIHNERRVDWLFRGAVY
HSYLTIFGQIPGYIDGVNFNPEHCSPNGTDPYKPKCPESDATQQRPAFPEWLTVLLLC
LYLLFTNILLLNLLIAMFNYTFQQVQEHTDQIWKFQRHDLIEEYHGRPAAPPPFILLS
HLQLFIKRVVLKTPAKRHKQLKNKLEKNEEAALLSWEIYLKENYLQNRQFQQKQRPEQ
KIEDISNKAGLELWGSRTSSVCKSRQFLHLTVVESRGSEKAPVTTLACLQGCLGKHGR
VDAMVDLLDLDPLKRSGSMEQRLASLEEQVAQTARALHWIVRTLRASGFSSEADVPTL
ASQKAAEEPDAEPGGRKKTEEPGDSYHVNARHLLYPNCPVTRFPVPNEKVPWETEFLI
YDPPFYTAERKDAAAMDPMGDTLEPLSTIQYNVVDGLRDRRSFHGPYTVQAGLPLNPM
GRTGLRGRGSLSCFGPNHTLYPMVTRWRRNEDGAICRKSIKKMLEVLVVKLPLSEHWA
LPGGSREPGEMLPRKLKRILRQEHWPSFENLLKCGMEVYKGYMDDPRNTDNAWIETVA
VSVHFQDQNDVELNRLNSNLHACDSGASIRWQVVDRRIPLYANHKTLLQKAAAEFGAH
Y"
BASE COUNT 1066 a 1605 c 1598 g 947 t
ORIGIN
1 tgggggtctc agaatggagc cctcagccct gaggaaagct ggctcggagc aggaggaggg
61 ctttgagggg ctgcccagaa gggtcactga cctggggatg gtctccaatc tccggcgcag
121 caacagcagc ctcttcaaga gctggaggct acagtgcccc ttcggcaaca atgacaagca
181 agaaagcctc agttcgtgga ttcctgaaaa catcaagaag aaagaatgcg tgtattttgt
241 ggaaagttcc aaactgtctg atgctgggaa ggtggtgtgt cagtgtggct acacgcatga
301 gcagcacttg gaggaggcta ccaagcccca caccttccag ggcacacagt gggacccaaa
361 gaaacatgtc caggagatgc caaccgatgc ctttggcgac atcgtcttca cgggcctgag
421 ccagaaggtg aaaaagtacg tccgagtctc ccaggacacg ccctccagcg tgatctacca
481 cctcatgacc cagcactggg ggctggacgt ccccaatctc ttgatctcgg tgaccggggg
541 ggccaagaac ttcaacatga agccgcggct gaagagcatt ttccgcagag gcctggtcaa
601 ggtggctcag accacagggg cctggatcat cacagggggg tcccacaccg gcgtcatgaa
661 gcaggtaggc gaggcggtgc gggacttcag cctgagcagc agctacaagg aaggcgagct
721 catcaccatc ggagtcgcca cctggggcac tgtccaccgc cgcgagggcc tgatccatcc
781 cacgggcagc ttccccgccg agtacatact ggatgaggat ggccaaggga acctgacctg
841 cctagacagc aaccactctc acttcatcct cgtggacgac gggacccacg gccagtacgg
901 ggtggagatt cctctgagga ccaggctgga gaagttcata tcggagcaga ccaaggaaag
961 aggaggtgtg gccatcaaga tccccatcgt gtgcgtggtg ctggagggcg gcccgggcac
1021 gttgcacacc atcgacaacg ccaccaccaa cggcaccccc tgtgtggttg tggagggctc
1081 gggccgcgtg gccgacgtca ttgcccaggt ggccaacctg cctgtctcgg acatcactat
1141 ctccctgatc cagcagaaac tgagcgtgtt cttccaggag atgtttgaga ccttcacgga
1201 aagcaggatt gtcgagtgga ccaaaaagat ccaagatatc gtccggaggc ggcagctgct
1261 gactgtcttc cgggaaggca aggatggtca gcaggacgtg gatgtggcca tcttgcaggc
1321 cttgctgaaa gcctcacgga gccaagacca ctttggccac gagaactggg accaccagct
1381 gaaactggca gtggcatgga atcgcgtgga cattgcccgc agtgagatct tcatggatga
1441 gtggcagtgg aagccttcag atctgcaccc cacgatgaca gctgcactca tctccaacaa
1501 gcctgagttt gtgaagctct tcctggagaa cggggtgcag ctgaaggagt ttgtcacctg
1561 ggacaccttg ctctacctgt acgagaacct ggacccctcc tgcctgttcc acagcaagct
1621 gcagaaggtg ctggtggagg atcccgagcg cccggcttgc gcgcccgcgg cgccccgcct
1681 gcagatgcac cacgtggccc aggtgctgcg ggagctgctg ggggacttca cgcagccgct
1741 ttatccccgg ccccggcaca acgaccggct gcggctcctg ctgcccgttc cccacgtcaa
1801 gctcaacgtg cagggagtga gcctccggtc cctctacaag cgttcctcag gccatgtgac
1861 cttcaccatg gaccccatcc gtgaccttct catttgggcc attgtccaga accgtcggga
1921 gctggcagga atcatctggg ctcagagcca ggactgcatc gcagcggcct tggcctgcag
1981 caagatcctg aaggaactgt ccaaggagga ggaggacacg gacagctcgg aggagatgct
2041 ggcgctggcg gaggagtatg agcacagagc catcggggtc ttcaccgagt gctaccggaa
2101 ggacgaagag agagcccaga aactgctcac ccgcgtgtcc gaggcctggg ggaagaccac
2161 ctgcctgcag ctcgccctgg aggccaagga catgaagttt gtgtctcacg ggggcatcca
2221 ggccttcctg accaaggtgt ggtggggcca gctctccgtg gacaatgggc tgtggcgtgt
2281 gaccctgtgc atgctggcct tcccgctgct cctcaccggc ctcatctcct tcagggagaa
2341 gaggctgcag gatgtgggca cccccgcggc ccgcgcccgt gccttcttca ccgcacccgt
2401 ggtggtcttc cacctgaaca tcctctccta cttcgccttc ctctgcctgt tcgcctacgt
2461 gctcatggtg gacttccagc ctgtgccctc ctggtgcgag tgtgccatct acctctggct
2521 cttctccttg gtgtgcgagg agatgcggca gctcttctat gaccctgacg agtgcgggct
2581 gatgaagaag gcagccttgt acttcagtga cttctggaat aagctggacg tcggcgcaat
2641 cttgctcttc gtggcagggc tgacctgcag gctcatcccg gcgacgctgt accccgggcg
2701 cgtcatcctc tctctggact tcatcctgtt ctgcctccgg ctcatgcaca tttttaccat
2761 cagtaagacg ctggggccca agatcatcat tgtgaagcgg atgatgaagg acgtcttctt
2821 cttcctcttc ctgctggctg tgtgggtggt gtccttcggg gtggccaagc aggccatcct
2881 catccacaac gagcgccggg tggactggct gttccgaggg gccgtctacc actcctacct
2941 caccatcttc gggcagatcc cgggctacat cgacggtgtg aacttcaacc cggagcactg
3001 cagccccaat ggcaccgacc cctacaagcc taagtgcccc gagagcgacg cgacgcagca
3061 gaggccggcc ttccctgagt ggctgacggt cctcctactc tgcctctacc tgctcttcac
3121 caacatcctg ctgctcaacc tcctcatcgc catgttcaac tacaccttcc agcaggtgca
3181 ggagcacacg gaccagattt ggaagttcca gcgccatgac ctgatcgagg agtaccacgg
3241 ccgccccgcc gcgccgcccc ccttcatcct cctcagccac ctgcagctct tcatcaagag
3301 ggtggtcctg aagactccgg ccaagaggca caagcagctc aagaacaagc tggagaagaa
3361 cgaggaggcg gccctgctat cctgggagat ctacctgaag gagaactacc tccagaaccg
3421 acagttccag caaaagcagc ggcccgagca gaagatcgag gacatcagca ataaggcagg
3481 gctggagctt tgggggtcaa ggacaagctc tgtctgcaaa tctagacagt tcctgcatct
3541 cacggtggtg gaatcacgcg ggtccgagaa ggctccagta accaccctcg catgtttgca
3601 aggctgtctg ggaaaacatg gcagggttga cgccatggtg gacctgctgg acctggaccc
3661 actgaagagg tcgggctcca tggagcagag gttggcctcc ctggaggagc aggtggccca
3721 gacagcccga gccctgcact ggatcgtgag gacgctgcgg gccagcggct tcagctcgga
3781 ggcggacgtc cccactctgg cctcccagaa ggccgcggag gagccggatg ctgagccggg
3841 aggcaggaag aagacggagg agccgggcga cagctaccac gtgaatgccc ggcacctcct
3901 ctaccccaac tgccctgtca cgcgcttccc cgtgcccaac gagaaggtgc cctgggagac
3961 ggagttcctg atctatgacc caccctttta cacggcagag aggaaggacg cggccgccat
4021 ggaccccatg ggagacaccc tggagccact gtccacgatc cagtacaacg tggtggatgg
4081 cctgagggac cgccggagct tccacgggcc gtacacagtg caggccgggt tgcccctgaa
4141 ccccatgggc cgcacaggac tgcgtgggcg cgggagcctc agctgcttcg gacccaacca
4201 cacgctgtac cccatggtca cgcggtggag gcggaacgag gatggagcca tctgcaggaa
4261 gagcataaag aagatgctgg aagtgctggt ggtgaagctc cctctctccg agcactgggc
4321 cctgcctggg ggctcccggg agccagggga gatgctacct cggaagctga agcggatcct
4381 ccggcaggag cactggccgt cttttgaaaa cttgctgaag tgcggcatgg aggtgtacaa
4441 aggctacatg gatgacccga ggaacacgga caatgcctgg atcgagacgg tggccgtcag
4501 cgtccacttc caggaccaga atgacgtgga gctgaacagg ctgaactcta acctgcacgc
4561 ctgcgactcg ggggcctcca tccgatggca ggtggtggac aggcgcatcc cactctatgc
4621 gaaccacaag accctcctcc agaaggcagc cgctgagttc ggggctcact actgactgtg
4681 ccctcaggct gggcggctcc agtccataga cgtttccccc agaaaccagg gcttctctct
4741 cctgagcctg gccaggactc aggctgttcc tgggccctgc acatgatggg gtttggtgga
4801 cccagtgccc ctcacggctg ccgcaagtct gctgcagatg acctcatgaa ctggaagggg
4861 tcaaggtgac ccgggaggag agctcaagac agggcacagg ctactcagag ctgaggggcc
4921 cctgggaccc ttggccatca ggcgaggggc tgggcctgtg cagctgggcc cttggccaga
4981 gtccactccc ttcctggctg tgtcaccccg agcagctcat ccaccatgga ggtcatcggc
5041 ctgaggcaag ttccccggag agtcggggtc ccctgtggcc ccctcaggcc tatgtctgtg
5101 aggaaggggc cctgccactc tccccaagag ggcctccatg tttcgaggtg cctcaacatg
5161 gagccttgcc tggcctgggc taggggcact gtctgaactc ctgactgtca ggataa
//